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Adam Pickrum

@apickrum.bsky.social
603 followers 344 following 22 posts

Postdoc at St. Jude with the Torres lab. Staphylococcal infection biology. Continuously pondering why bacteria win all the time.

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Reposted by Adam Pickrum
Contagion® @contagionlive.bsky.social · 25/09/2026
Listen to our conversation with Joseph Zackular, PhD, who provides insights around his work including how the colonization reshapes gut development, as well as some potential intervention strategies to shield neonates. #IDsky #Medsky www.contagionlive.com/view/asympto...
contagionlive.com
Asymptomatic C difficile Colonization in Infants Doesn’t Mean Benign | Contagion Live
A new study in infants challenges the long-standing belief about the pathogen’s effects in the youngest pediatric population. Senior author Joseph Zackular, PhD, provides insights around his work incl...
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Brian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 19/08/2026
Midwest Microbial Pathogenesis Conference Sepember 25-27, 2026 Minneapolis, MN #MicroSky 🦠🧫🧪🧬
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Heran Darwin, PhD @heran.bsky.social · 10/08/2026
BlueSky doesn't seem to spread the word around as effectively as that other app so I'm reposting this incredible opportunity again (and again!). Please repost and spread the word to strong candidates. Thank you!
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Andrew Darwin @durkdarwin.bsky.social · 22/07/2026
After a bit of a rough patch my lab's funding situation has taken a significant upturn, so if you're looking for a Postdoc position please keep us in mind...Pseudomonas aeruginosa genetics, regulation, and physiology - with a focus on the cell envelope. Please repost. andrewdarwinlab.org
andrewdarwinlab.org
Microbiology | Andrew Darwin Lab | United States
Andrew Darwin Laboratory website. Academic Microbiology research laboratory at NYU School of Medicine. New York, NY, USA.
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Stella Hurtley @smhsci.bsky.social · 26/06/2026
Out now in @science.org Antibiotics stimulate protein transfer to persister cells | Science www.science.org/doi/10.1126/...
science.org
Antibiotics stimulate protein transfer to persister cells
The exchange of biological matter between bacterial cells drives adaptation and evolution. However, whether bacteria can exchange functional proteins remains unclear. In this work, we found that antib...
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Valeria Reyes Ruiz @reyesruiz.bsky.social · 25/06/2026
Our lab is hiring an enthusiastic and motivated research specialist to study host-pathogen interactions in the context of S. aureus infection. For more information, see below: Lab website: www.reyesruizlab.org jobs.wisc.edu/jobs/researc...
jobs.wisc.edu
Research Specialist - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:Academic StaffEmployment Type...
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Adam Pickrum @apickrum.bsky.social · 18/06/2026
Missing the parade but my tubes get #knicks colors today! Maybe some of that championship energy will rub off onto my experiment.
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The New Yorker @newyorker.com · 14/06/2026
A fan’s late-night notes. www.newyorker.com/sports/sport...
newyorker.com
The Knicks Take the Series—Seize the Joy!
A fan’s late-night notes.
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Salvador Almagro-Moreno @bioetry.bsky.social · 17/05/2026
Thinking of doing a PhD with a focus on infectious diseases? My lab is seeking enthusiastic students to investigate the emergence and transmission of pathogenic Vibrios. Join us at St. Jude Children's Research Hospital, an extraordinary research center! www.stjude.org/education-tr...
stjude.org
Biomedical Sciences PhD Program
St. Jude offers a unique biomedical PhD program at one of the world’s premier pediatric research centers. Find out about admissions, courses, faculty and more.
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Erin Green @erinrgreen.bsky.social · 29/04/2026
Excited to share the final part of my postdoc work, where we investigate the impact of antimicrobial treatment on susceptibility to hospital-acquired Acinetobacter baumannii pneumonia. Thanks to our amazing group of collaborators for their contributions to this study! www.pnas.org/doi/10.1073/...
pnas.org
The intestinal microbiota impacts nutritional immunity and resistance to Acinetobacter baumannii pneumonia | PNAS
Broad-spectrum antibiotics are frequently administered to intensive care unit patients as part of empiric care. This treatment has been associated ...
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Andreas Peschel @andreaspeschel.bsky.social · 27/04/2026
Commensal bacteria are crucial for microbiome interactions and pathogen exclusion but are often very difficult to tackle genetically. Our new paper describes an intriguing advance: @cmfi.bsky.social @dzif.bsky.social @spp2330.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Genetic modification of intractable bacterial clones by heat shock-facilitated phage transduction
Increasing recognition of commensal bacteria as essential for microbiome integrity and pathogen exclusion underscores the urgency of molecularly chara…
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The New York Times @nytimes.com · 26/04/2026
The Trump administration on Friday dismissed members of an independent board that oversees the National Science Foundation, which finances much of the public scientific research in the U.S.
nyti.ms
Trump Fires Board Members of Group That Oversees U.S. Science Funding
The dismissals from an independent board that oversees the National Science Foundation marked the president’s latest assault on scientific research organizations.
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Melanie Blokesch @mblokesch.bsky.social · 10/04/2026
Excited to share our new paper out today in @science.org 🎉 We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩 Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/ #microsky #phagesky www.science.org/doi/10.1126/...
science.org
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Nature @nature.com · 02/03/2026
Nature research paper: Convergent MurJ flippase inhibition by phage lysis proteins go.nature.com/4aAWHKb
go.nature.com
Convergent MurJ flippase inhibition by phage lysis proteins - Nature
A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial development.
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Molecular Microbiology @molmicrounihoh.bsky.social · 31/01/2026
🫴 Fantastic work: DNA recognition-mimicry switch governs induction in arbitrium phages: www.sciencedirect.com/science/arti... @spp2330.bsky.social #subtiwiki @cp-cellhostmicrobe.bsky.social
sciencedirect.com
A DNA recognition-mimicry switch governs induction in arbitrium phages
Temperate phages integrate multiple information sources to regulate lysis-lysogeny transitions. SPbeta-like phages use arbitrium signaling and DNA dam…
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Kranzusch Lab @kranzuschlab.bsky.social · 28/01/2026
Great new story from Sophie Helaine and Molly Sargen! www.helainelab.com
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Victor J. Torres @torreslab.bsky.social · 24/01/2026
Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by @sunnyshinlab.bsky.social www.grc.org/microbial-to...
grc.org
2026 Microbial Toxins and Pathogenicity Conference GRC
The 2026 Gordon Research Conference on Microbial Toxins and Pathogenicity will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.
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Emmanuele Severi @emmseveri.bsky.social · 24/01/2026
#microsky #phagesky #phage defence www.science.org/doi/10.1126/...
science.org
Bacteriophages mobilize bacterial defense systems via lateral transduction
Bacteriophages and PICIs spread bacterial defenses via lateral transduction, shaping microbial immunity and pathogen evolution.
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Aaron Whiteley @aaronwhiteley.bsky.social · 18/01/2026
I’m thrilled to share our work on phage triggers of the bacterial immune system in its final form @natmicrobiol.nature.com www.nature.com/articles/s41...
nature.com
A phage protein screen identifies triggers of the bacterial innate immune system - Nature Microbiology
A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.
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Kimberly Kline 🏔 @kimingeneva.bsky.social · 17/01/2026
Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.
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Salvador Almagro-Moreno @bioetry.bsky.social · 06/01/2026
Registration and abstract submission for Vibrio 2026 is now open! The preliminary program, featuring an exceptional speaker lineup, is also available. Please share! ♻️
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Joe Zackular @joeyzacks.bsky.social · 05/01/2026
Really happy to have this study led by @ashleyweiss.bsky.social and Jilarie Santos-Santiago published in the Journal of Bacteriology (@asm.org) over the holiday break!! Always awesome to team up with the amazing @ritatamayo.bsky.social lab! #Cdiff #enterococci journals.asm.org/doi/10.1128/...
journals.asm.org
Enterococcus faecalis modulates phase variation in Clostridioides difficile | Journal of Bacteriology
Clostridioides difficile is an enteric pathogen with critical implications for public health. The microbial ecosystem in which C. difficile resides shapes the behavior and fitness of C. difficile; how...
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Chris Peritore-Galve @fcperitore.bsky.social · 31/12/2025
The Peritore Lab officially opens its doors in 2026! I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j... #MicroSky
peritorelab.com
Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center
Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center
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emggroupucph.bsky.social @emggroupucph.bsky.social · 29/12/2025
[1/3] Is your favorite bacterial isolate hiding a surprise lytic virus with a VERY different lifestyle? Finally I can proudly say that our paper on persistent phages is out in Nature Microbiology. rdcu.be/eWJEp. Well done @peterdoug.bsky.social
rdcu.be
Persistent virulent phages exist across bacterial isolates
Nature Microbiology - The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical...
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Heran Darwin, PhD @heran.bsky.social · 22/12/2025
While everyone is hustling for the holidays, hopefully folks will have time to submit abstracts or register for #ASMMicrobe2026 in DC! Please repost!
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Jan-Willem Veening @veeninglab.com · 19/12/2025
Now online @natmicrobiol.nature.com! www.nature.com/articles/s41...
nature.com
Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials - Nature Microbiology
Streptococcal S protein activates a peptidoglycan cell wall repair and modification complex to promote resistance of Streptococcus pneumoniae to lysozyme and LL-37, and increase virulence during infec...
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Tania Wong @taniawong.bsky.social · 23/11/2025
🚨 New review out from our lab! We’re pleased to share our latest article @cp-cellreports.bsky.social exploring the airway immunometabolic response to common bacterial and viral pathogens. Shout out to @ridhimaw.bsky.social, Eric Tang and Roy Wong. 👉 Read it here: www.cell.com/cell-reports...
cell.com
Airway immunometabolic responses during pulmonary bacterial and viral infections
Wadhwa et al. examine how respiratory bacterial and viral pathogens exploit host metabolism to evade immune responses and influence disease outcomes. They underscore the need for deeper insight into i...
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Joe Zackular @joeyzacks.bsky.social · 19/11/2025
Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
keysym.us
Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection | Keystone Symposia
Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!
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Adam Pickrum @apickrum.bsky.social · 12/10/2025
#Gopackgo !!
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Roni Odai @rodai.bsky.social · 02/10/2025
Viral AlphaFold Database (VAD) is live in Science Advances ~27,000 predicted viral protein monomers & homodimers Conserved folds across bacteria, archaea & eukaryotic viruses New toxin–antitoxin system KreTA uncovered Vast “functional darkness” remains uncharted www.science.org/doi/10.1126/...
science.org
The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes
VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.
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Heran Darwin, PhD @heran.bsky.social · 07/10/2025
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Shabaana Khader @khadershabaana.bsky.social · 05/10/2025
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu Apply here apply.interfolio.com/174404
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Erin Green @erinrgreen.bsky.social · 04/10/2025
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
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Jordan Jastrab @jordanjastrab.bsky.social · 26/09/2025
Thrilled to share my work from the @jkagan1.bsky.social lab! TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection! www.biorxiv.org/content/10.1... #microsky #immunosky
biorxiv.org
Wall teichoic acid is required for DNA-triggered innate immune receptor activation by Staphylococcus aureus
Receptors that stimulate inflammation are commonly activated by ligands that are buried within microbial cells. The mechanisms that facilitate immunostimulatory ligand release from microbes during inf...
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Tominaga K. (tomiken) @pacyc184.bsky.social · 26/09/2025
Dual transposon sequencing profiles the genetic interaction landscape in bacteria | Science www.science.org/doi/full/10.1126/sc…
science.org
Dual transposon sequencing profiles the genetic interaction landscape in bacteria
Gene redundancy complicates systematic characterization of gene function as single-gene deletions may not produce discernible phenotypes. We report dual transposon sequencing (dual Tn-seq), a platform for assaying the fitness of a comprehensive double ...
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Joe Bondy-Denomy @jbdsf.bsky.social · 25/09/2025
Our Department of Microbiology & Immunology at UCSF is running a faculty search this year for a new Assistant Professor! Please see the ad below for details. Searching for a great colleague, mentor, and scientist! aprecruit.ucsf.edu/JPF05807
aprecruit.ucsf.edu
Microbiology and Immunology – Faculty Position (Ladder Rank) – Assistant Professor
University of California, San Francisco is hiring. Apply now!
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Kyle T. Enriquez @kyletenriquez.bsky.social · 23/09/2025
Last month I attended the #GRS and #GRC on Staphylococcal Diseases. The conference was an excellent opportunity to meet new colleagues, learn with and about the vibrant #Staphylococcal community, and get ideas on #Zinc #ZNG1 research, coming soon
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Vaughn Cooper @vscooper.micropopbio.org · 23/09/2025
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine. 1) MMG (my dept): fundamental research in med micro 2) Peds ID / I4Kids institute 3) Center for Vaccine Research 🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
linkedin.com
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...
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Salvador Almagro-Moreno @bioetry.bsky.social · 18/09/2025
Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year! Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists! event.fourwaves.com/vibrio2026/p...
event.fourwaves.com
Vibrio2026: The International Meeting on the Biology of Vibrios
Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios
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Adam Pickrum @apickrum.bsky.social · 12/09/2025
Wrapped up another great #cshlhost25 meeting! Such a special place to share the awesome science going on around the world.
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Salvador Almagro-Moreno @bioetry.bsky.social · 23/08/2025
Interview with yours truly on what to do to protect yourself against the flesh-eating pathogen Vibrio vulnificus for the Associated Press apnews.com/article/vibr...
apnews.com
How to protect yourself from Vibrio vulnificus, the bacteria found in some coastal waters
States are warning beachgoers about a summertime surge in infections from a frightening, flesh-eating bacteria found in coastal waters.
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Kevin Forsberg @kvnforsberg.bsky.social · 18/08/2025
Come be my colleague! I've been very happy at UTSW Micro. Why? Its a supportive environment full of excellent people. There's strong ambition, reflexive empathy, and excellent resources.
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Adam Pickrum @apickrum.bsky.social · 02/08/2025
After some time in sunny Barcelona, I’m excited to kick off the #staphGRC this week! Ready for some awesome science.
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Francis Alonzo @francisalonzo12.bsky.social · 01/08/2025
Happy to share Iván’s first-author pub from the lab! www.cell.com/cell-reports...
cell.com
Staphylococcus aureus exploits lipoic acid salvage to combat host oxidative stress
Acosta et al. find that ADP-ribosylation of the lipoic acid carrier protein GcvH-L promotes Staphylococcus aureus resistance to oxidative burst and facilitates infection. ADP-ribosylation leads to a s...
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Andreas Peschel @andreaspeschel.bsky.social · 28/07/2025
"Among all bacterial species, S. aureus ranks second only to E. coli in the number of scientific publications." It was a pleasure to contribute to this review, with @pinholab.bsky.social and Friedrich Götz journals.asm.org/doi/10.1128/...
journals.asm.org
Staphylococcus aureus: a model for bacterial cell biology and pathogenesis | Journal of Bacteriology
When talking about Staphylococcus aureus, one usually has in mind the diseases that can be caused by this bacterium, ranging from mild skin and soft tissue infections, such as abscesses and furuncles,...
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Joe Zackular @joeyzacks.bsky.social · 26/07/2025
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
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Andreas Bäumler @abaumler.bsky.social · 22/07/2025
Infection and Immunity is now welcoming nominations for highly promising scientists at the assistant professor level (or equivalent) to submit research to the next New Voices in Microbiology Collection! Please nominate by the August 18 deadline using the below link: app.asm.org/account/logi...
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Science Magazine @science.org · 21/07/2025
"I can’t predict the next hiring cycle or the next election. But I can keep doing the science I love while I still have a bench." #ScienceWorkingLife scim.ag/4lXUwDa
An illustration of a woman standing at a dead end looking at different roads and buildings. Text reads: My academic job offer was rescinded. I’ll keep going—but U.S. researchers are running out of road.
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Cell Host & Microbe @cp-cellhostmicrobe.bsky.social · 16/07/2025
Methylglyoxal: antibacterial effector Methylglyoxal produced by infected macrophages upon transition to aerobic glycolysis acts as an innate immune antimicrobial effector that bacteria must detoxify for virulence and to prevent mutations www.cell.com/cell-host-mi...
cell.com
Methylglyoxal is an antibacterial effector produced by macrophages during infection
Infected macrophages that transition to aerobic glycolysis produce the reactive aldehyde methylglyoxal. In this study, Anaya-Sanchez et al. use both host and bacterial genetics to show that methylglyo...
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Kim Davis @davislabjhu.bsky.social · 10/07/2025
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !
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