iiinova — where your digital self keeps evolving

Reposted by Tania Wong

Gaia Trincucci @gaiajexpmed.bsky.social · 21/12/2025

Today’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress. www.nature.com/articles/s41...

nature.com

Neutrophils preserve energy storage in sympathetically activated adipocytes - Nature

Neutrophil-derived IL-1β has a role in preserving lipid stores during metabolic stress.

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Tania Wong @taniawong.bsky.social · 07/12/2025

🚀 We’re hiring a Postdoc! Seeking expertise in spatial metabolite imaging and/or mass spectrometry to study how host metabolism shapes immune responses. If you're creative, collegial, and excited to push boundaries, we’d love to hear from you. Please share! 🔗 www.nature.com/naturecareer...

nature.com

Postdoctoral Research Scientist - Newark, New Jersey (US) job with Dr Tania Wong | 12848863

Rutgers is currently seeking a Postdoc Research Scientist to join the Center for Immunity and Inflammation (CII) at the New Jersey Medical School.

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Tania Wong @taniawong.bsky.social · 08/08/2025

Truly honored and thankful to receive an R35 MIRA grant from NIGMS - grateful for the support and the opportunity to pursue our research on diet-mediated immunometabolic responses in the context of infectious diseases.

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Tania Wong @taniawong.bsky.social · 01/08/2025

Pleased to share our latest study @natcomms.nature.com! We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work! www.nature.com/articles/s41...

nature.com

Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia - Nature Communications

This study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC, to support its metabolic fi...

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Tania Wong @taniawong.bsky.social · 29/07/2025

Appreciate the Rutgers News feature on this year’s i3D Symposium. It was a great opportunity to bring together researchers across multiple disciplines. Thanks to everyone who contributed to a successful event. www.rutgers.edu/news/expandi...

rutgers.edu

Expanding Institute, Growing Reach: i3D’s Symposium Shows Its Momentum

The Rutgers Health Institute for Infectious and Inflammatory Diseases uses a fast-expanding conference to trade fresh data, forge collaborations and spotlight new talent.

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Reposted by Tania Wong

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 14/06/2025

🄰🅆🄴🅂🄾🄼🄴 Stubbusch et al 𝘚𝘊𝘐𝘌𝘕𝘊𝘌 Bacteria 🦠 repurpose Type VI Secretion Systems based on environmental cues: Nutrient-rich environments ➜ kill competitors Under starvation ➜ lyse neighbors to scavenge their nutrients Even “non-pathogens” shift from competition to predation as a survival strategy

science.org

Antagonism as a foraging strategy in microbial communities

In natural habitats, nutrient availability limits bacterial growth. We discovered that bacteria can overcome this limitation by acquiring nutrients by lysing neighboring cells through contact-dependen...

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Tania Wong @taniawong.bsky.social · 23/05/2025

Congratulations @daneparkerlab.com! Rutgers NJ Medical School Faculty of the Year Award! Well deserved!

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Tania Wong @taniawong.bsky.social · 19/04/2025

Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇 www.biorxiv.org/content/10.1...

biorxiv.org

Regulation of airway fumarate by host and pathogen promotes S. aureus pneumonia

Staphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ...

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Reposted by Tania Wong

Waggoner Lab @labwaggoner.bsky.social · 18/04/2025

Systemic inflammation impairs myelopoiesis and interferon type I responses in humans www.nature.com/articles/s41... @natimmunol.bsky.social

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Reposted by Tania Wong

Waggoner Lab @labwaggoner.bsky.social · 17/04/2025

Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes @cp-cellreports.bsky.social www.cell.com/cell-reports...

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Tania Wong @taniawong.bsky.social · 12/04/2025

Thrilled to present my lab’s work at @escmid.bsky.social. Also chuffed to have bumped into fellow @klebclub.bsky.social member, Renee @fleemanlab.bsky.social!

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Tania Wong @taniawong.bsky.social · 21/02/2025

🎉 It's official! Our lab website is LIVE! Come check it out to learn about our research, meet the team, and see what exciting things we're working on! www.taniawonglabrutgers.com

taniawonglabrutgers.com

Tania Wong Laboratory - Rutgers Center for Immunity and Inflammation

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Reposted by Tania Wong

Victor J. Torres @torreslab.bsky.social · 17/01/2025

Come and join our team at St. Jude Children's Research Hospital! We are seeking a Sr Scientist to advance our research on immune responses to infection/vaccination. This is a financially stable position offering a highly competitive salary and excellent benefits. talent.stjude.org/careers/jobs...

talent.stjude.org

Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee | St. Jude Careers

St. Jude Careers is hiring a Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee. Review all of the job details and apply today!

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Reposted by Tania Wong

Christian Frezza @frezzalab.bsky.social · 16/01/2025

Thanks to @cp-trendsendomet.bsky.social for giving us the opportunity to write about our favourite metabolite, fumarate. www.sciencedirect.com/science/arti...

sciencedirect.com

Fumarate

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Reposted by Tania Wong

Science Magazine @science.org · 10/01/2025

Scientists have identified functional differences between human and mouse PD-1, which could impact preclinical research on cancer immunotherapies. Read more in #ScienceImmunology:

scim.ag

Functional differences between rodent and human PD-1 linked to evolutionary divergence

A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.

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Reposted by Tania Wong

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 27/11/2024

Important stuff Immune checkpoint inhibitors that block PD-1 pathway effective vs. many cancers New @IMMUNITY: impaired memory B cell development and IgG/A responses in humans and mice deficient in PD-1 signaling This dysregulation may explain ⬆️ risk of infection or autoimmunity in these patients

cell.com

Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling

Ogishi, Kitaoka, et al. examine humans deficient in PD-1 and PD-L1 as well as associated mouse models and find that PD-1 and PD-L1 promote B cell memory and antibody responses through both T cell-depe...

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Reposted by Tania Wong

David Finlay @davidfinlaytcd.bsky.social · 23/11/2024

Interesting, a fluorescent biosensors to illuminate arginine metabolism in cells, mice, and clinical samples. #Arginine #biosensor Lighting up arginine metabolism reveals its functional diversity in physiology and pathology: Cell Metabolism www.cell.com/cell-metabol...

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