Endogenous mechanisms that restrain inflammation remain incompletely understood. Colussi et al. identify membrane phospholipids as reservoirs of endogenous nitrated fatty acids that are rapidly mobilized during inflammatory stress. Release of NO2-CLA suppresses inflammatory signaling and preserves vascular homeostasis, revealing a previously unrecognized anti-inflammatory reserve that becomes depleted during disease.

Large networks are particularly beneficial to researchers in under-represented groups.

Popular vendors’ catalogs feature more than 18,000 manipulated images

Modulating the intracellular labile iron pool (LIP) has emerged as a promising strategy to induce ferroptosis in cancer cells, offering a way to overcome resistance to apoptosis-based therapies. One o...

Modulating the intracellular labile iron pool (LIP) has emerged as a promising strategy to induce ferroptosis in cancer cells, offering a way to overcome resistance to apoptosis-based therapies. One o...

This Review examines the chemical complexity of selenium biology and the tools available to study it. Defining current limitations in detecting selenium species outlines pathways toward a more precise...

This Review examines the chemical complexity of selenium biology and the tools available to study it. Defining current limitations in detecting selenium species outlines pathways toward a more precise...

O pesquisador brasileiro José Pedro Friedmann Angeli foi premiado por avanços na ferroptose, mecanismo que pode combater tumores agressivos e resistentes.

The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge, wishes to appoint two post-doctoral Research Associates to join the research group of Prof. Mike Murphy at t...

The Heidelberg Medical Faculty of the University of Excellence Heidelberg is an outstanding location for innovative research, both nationally and i...

A multi-institute research team, led by Prof. José Pedro Friedmann Angeli, examined the activity of ferroptosis suppressor protein 1 (FSP1) in protecting against phospholipid peroxidation and ferropto...

Hinshaw et al. determine the molecular basis for TRIM21 recruitment to the nuclear pore protein NUP98, showing that an induced protein-protein interface drives the potency and selectivity of the molecular glue mechanism.

Oncogenesis - Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma

Clause says those aged up to 45 may need permission from armed forces to leave country for more than three months

The 2026 Gordon Research Conference on Thiol-Based Redox Regulation and Signaling will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.

After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...

The following full-time (38.5 hours/week) position is to be filled as soon as possible in the Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Fri...

After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...

Nature Structural & Molecular Biology, Published online: 13 March 2026; doi:10.1038/s41594-026-01760-4The oxidoreductase FSP1 recycles radical-trapping antioxidants that suppress oxidative lipid damage and ferroptosis. A series of genetic screens reveal a key role for the vitamin B2 metabolite flavin adenine dinucleotide in stabilizing FSP1, preventing its proteasomal degradation and promoting ferroptosis suppression.

The 2026 Gordon Research Conference on Cell Death will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

The two federal immigration agents who fired on Minneapolis protester Alex Pretti are identified in government records as Border Patrol agent Jesus Ochoa and Customs and Border Protection officer Raym...

For the past 10 years the dissident artist has lived in Germany, the UK and now Portugal, never once setting foot in his native country, where people with far less controversial pasts have faced arbit...

A large-scale analysis of 117 mammal species found that preventing reproduction is associated with longer lifespans, suggesting a strong link between reproductive activity and life expectancy. Why do ...