Karagiannis and Theodorou et al. show that excess lipids in obesity impair adipose ILC2s via acetyl-CoA carboxylase 1 (ACC1). Deletion of ACC1 disrupts the citrate shuttle and the NAD+/NADH balance, i...

The following full-time (38.5 hours/week) position is to be filled as soon as possible in the Institute of Clinical Chemistry and Clinical Pharmacology at the Faculty of Medicine of the Rheinische Fri...

The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…

Tuft cells constitutively express IL-25 to sustain ILC2 homeostasis in the intestine, but mechanisms driving IL-25 secretion have been unclear. Here, Feng et al. find that tuft cells express IL-17RB, ...

Sprenger et al. used a systematic approach to identify how mitochondria remodel their metabolome in response to exercise. The diet-derived, atypical amino acid ergothioneine (EGT) accumulates in muscl...

Der neue US-Präsident zerstört Institutionen, Wissenschaft, die eigene Zukunft.

Ambroziak, Nencini, Pohle and colleagues identify a slowly emerging plasticity mechanism in a discrete set of hypothalamic preoptic neurons that is triggered by long-term heat exposure and that drives...

Liver X receptor drives epithelial Areg-mediated intestinal regeneration, while preventing tumour growth through adaptive immune responses.

The ketone body β-hydroxybutyrate can be used as an alternative carbon source by T cells to maintain their function during severe respiratory viral infections, including infection with&...