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Amelia Randich

@ameliarandich.bsky.social
1.3K followers 525 following 117 posts

Molecular evolution of cell morphology and growth mechanisms in alphaproteobacteria 👾 Assoc Prof of Biology at The U of Scranton 🥟

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Reposted by Amelia Randich
Typas Lab @typaslab.bsky.social · 19h
How does a single methyl group activate bacterial defence? Our new preprint, led by @pspatharas.bsky.social in collaboration with the group of @matthiaswilmanns.bsky.social, explains how a single DNA methylation event activates large retron assemblies. www.biorxiv.org/content/10.6...
biorxiv.org
Single-site DNA methylation activates retron defence by enabling effector tetramerisation
Retrons are unique among bacterial defence systems in using DNA to sense phage infection. They achieve this by producing multicopy single-stranded DNA (msDNA) that monitors the activity of DNA-targeti...
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Botanical Society of America @botsocamerica.bsky.social · 13/10/2026
Dreaming of a faculty job at a PUI? Join the #Botany360 "Interviewing and Preparing for a Career at a PUI" with Kalina Manoylov (Georgia College & State U.) and other PUI faculty. All career levels welcome. Oct. 30, 2026 9:00-10:30 am ET Free on Zoom Register: us02web.zoom.us/meeting/regi...
Flyer for a Botany360 event titled “Interviewing and Preparing for a Career at a PUI.” Date and time: October 30th, 2026, 9:00 to 10:30 am ET. Bullet points: “Get tips for interviewing for a faculty position at a primarily undergraduate institution” and “Network with a community of people with shared career goals.” A QR code is labeled “Register now!” Presenter: Kalina Manoylov, Georgia College & State University. Presented by the PUI section of the Botanical Society of America. The Botany360 and Botanical Society of America logos are shown.
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Reposted by Amelia Randich
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 02/10/2026
New in JB: Baker, Nizet et al. explore the role of monounsaturated fatty acid biosynthesis in the ability of Streptococcus to deal with envelope homeostasis and stress - highlighting species and context dependence. pubmed.ncbi.nlm.nih.gov/42565831/ @asm.org #JBacteriol @microsky.bsky.social
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Baylink Lab @baylinklab.bsky.social · 02/10/2026
Call for manuscripts on bacterial chemotaxis and swimming! I'm partnering with JoVE to assemble a new collection of method, reviews, and research. ➡️Abstracts due Nov. 23rd. I invite you to share your love (and knowledge) of swimming bacteria! www.jove.com/topical-coll... 🧪 🦠 🧫 #microsky
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DEI Virologist @kyt-thatsme.bsky.social · 01/10/2026
Hey Microbiology folks, 🦠🧫 Have thoughts about the new NIH Policy For Research Involving Biohazards? They are accepting comments! grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-112: Request for Comment: Draft NIH Biosafety Policy for Research Involving Biohazards
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Comment: Draft NIH Biosafety Policy for Research Involving Biohazards NOT-OD-26-112. NIH
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Will Ratcliff @wcratcliff.bsky.social · 30/09/2026
Application review for the GRC in Microbial Population Biology will start October 15th! Please apply before then if you are keen on coming. www.grc.org/microbial-po...
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Çağrı Çevrim @cagricevrim.bsky.social · 01/10/2026
Your favorite website for illustrations of almost all organisms is looking for donations to help cover its running costs! Please consider donating to help keep this open-source platform running: www.phylopic.org/images
phylopic.org
All Silhouette Images on PhyloPic
Browse all the free silhouette images in PhyloPic.
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Malcolm White @mfwhite2.bsky.social · 01/10/2026
Nicely executed study on phage anti-defence rdcu.be/M7mrq41uU7Ma
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Philipp Radler @radler92.bsky.social · 01/10/2026
The first paper of my PostDoc in Christa Schlepers group (@archaea-vienna.bsky.social) on the dynamics of Asgard archaea is now out in Nature! www.nature.com/articles/s41... This was a great team effort and I am looking forward to uncover the complex behavior of these cells further!
nature.com
Dynamic protrusions mediate crawling motility in Asgard archaea - Nature
Anoxic live-cell imaging shows actin-dependent crawling motility and dynamic protrusions in Asgard archaea, providing insights into cellular innovations that may have contributed to eukaryotic evoluti...
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Thibaut Brunet @thibautbrunet.bsky.social · 01/10/2026
Pre-eukaryotic ancestry of actin-based cell crawling 🤯 An instant must read
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Ákos T Kovács @evolvedbiofilm.bsky.social · 30/09/2026
The phenotypic landscape of the model firmicute Bacillus subtilis PNAS from Carol A. Gross www.pnas.org/doi/10.1073/...
pnas.org
The phenotypic landscape of the model firmicute Bacillus subtilis | PNAS
Firmicutes are gram-positive bacteria with important roles in human health, disease, and industry. However, more than a quarter of genes in the mod...
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Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 30/09/2026
When people in power deliver bad news to you, they expect you to just take punch, accept it, and move on. In these situations, we need to empower ourselves to reject the premise. I want you to look at three time points in the fight to save the academy of natural sciences with me. (Thread)
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Tanmay Bharat @tbharat-lab.bsky.social · 30/09/2026
Diverse S-layer anchoring mechanisms create an epiplasmic space in prokaryotic cell envelopes. Our review with @bupbuse.bsky.social and @vikramalva.bsky.social discussing a cellular compartment created by the S-layer out in Current Opinion in Microbiology. www.sciencedirect.com/science/arti...
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Vivek Mutalik @vivekmutalik.bsky.social · 29/09/2026
In our brand new 🥳 review, @hemaa-selvakumar.bsky.social & team pull a scattered literature in phage biology into a coherent framework for scaling up to engineering complex communities. We poured our hearts into this to share challenges & future opportunities for the nextGen!
Next generation application space with systematic characterization of phage-host interaction landscapes.
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Rich Meisel @richmeisel.bsky.social · 24/09/2026
We're hiring an Assistant or Associate Professor in Evolutionary Biology in my department at the university of Houston @uh-ecoevo.bsky.social Come be my colleague careers.uh.edu/jobs/assista...
careers.uh.edu
Assistant or Associate Professor - Evolutionary Biology - Houston, Texas, United States
Department: Biology and Biochemistry Salary: Commensurate with experience Description: The Department of Biology and Biochemistry at the University of Houston seeks to hire an evolutionary biolog...
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Maya Voichek @mayavoichek.bsky.social · 24/09/2026
Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)
AI-generated illustration of the soma-to-germline transmission of retrotransposons described in our work
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Anouk Willemsen @willemsenanouk.bsky.social · 24/09/2026
Why did some #viruses #evolve to be giants while others did not? ".. #giantViruses are typical viruses that evolved from smaller ones via accretion of genes recruited from the hosts." doi.org/10.1073/pnas... @mkrupovic.bsky.social & E. Koonin
doi.org
Why did some viruses evolve to be giants while others did not? | PNAS
Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The ...
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Reposted by Amelia Randich
Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 24/09/2026
Not read this in detail yet…but looks interesting and thought provoking….will it help or add fuel to fires on discussions around lab releases of organisms? Language-Model-Based Detection of Genetic Editing in Bacteria www.biorxiv.org/content/10.6...
biorxiv.org
Language-Model-Based Detection of Genetic Editing in Bacteria
Recent advances in genome editing allow easy genetic manipulation of bacteria, providing them with new traits, some of which could be hazardous, e.g. enhanced virulence or extended resistance to antib...
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Simonetta Gribaldo @sgribaldo.bsky.social · 23/09/2026
Interested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇
nature.com
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Manuel Kleiner @manuelkleiner.bsky.social · 08/09/2026
We are looking to hire a microbiology laboratory research technician here at NC State in Raleigh, NC. If you have experience in microbiology and/or LC-MS/MS please consider applying. Please repost! jobs.ncsu.edu/postings/234...
jobs.ncsu.edu
Microbiology Laboratory Research Technician
The Kleiner Lab at North Carolina State University is seeking a Research Technician to support research focused on complex microbial communities, microbial symbioses, and metaproteomics. Reporting to ...
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Julian Parkhill @julianparkhill.bsky.social · 08/09/2026
Chair in Bacteriology in Cambridge Department of Medicine. A great opportunity. Please circulate. www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Professor in the field of Bacteriology
Strengthening Cambridge's leadership in bacteriology research Bacterial infection and antimicrobial resistance remain among the most pressing global health challenges of our time. At Cambridge, the De...
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c0nc0rdance @c0nc0rdance.bsky.social · 07/09/2026
Kurt Füchslin captured this video of frozen methane bubbles in Sihlsee (Lake Sihl) in Switzerland. Deep in the depths, bacteria break down decaying organic matter, producing bubbles of methane. As they reach the thickening surface ice, they're trapped as flammable fart pancakes/ice art.
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Molecular Microbiology @molmicrounihoh.bsky.social · 03/09/2026
Wow: Flagellar toxicity: Flagellar synthesis is lytic for Bacillus subtilis in the absence of PBP1! 👇 www.pnas.org/doi/10.1073/... @pnas.org #subtiwiki #subtilis
pnas.org
Flagellar toxicity: Flagellar synthesis is lytic for Bacillus subtilis in the absence of PBP1 | PNAS
Flagella are large transenvelope nanomachines but how they transit the peptidoglycan in gram-positive bacteria is poorly understood. A recent model...
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Evgenii Protasov @evgenii-protasov.bsky.social · 07/09/2026
Defining the order of assembly of the Clostridioides difficile divisome complex #microbiology #Clostridia #MicroSky @asm.org journals.asm.org/doi/10.1128/...
journals.asm.org
Defining the order of assembly of the Clostridioides difficile divisome complex | Journal of Bacteriology
Bacterial cell division has been extensively studied in model systems, but little is known about how this essential process occurs in the clinically important pathogen Clostridioides difficile. Studie...
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Paul Rainey @paulbrainey.bsky.social · 07/09/2026
A beautiful piece of detective work by @honour.bsky.social + colleagues revealing the origins of Ralstonia disease of bananas on Martinique. As so often, ICEs (ICERs!) prove to be extraordinary capacitors for evolutionary change. Evolution for evolution's sake 🤔 doi.org/10.1093/gbe/...
doi.org
Interspecies Exchange of Mobile Genetic Elements During a Plant Disease Outbreak
Abstract. Outbreak sequencing provides insight into the origin and evolutionary processes acting on emerging pathogens. Sequencing a historic multihost out
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Ben Pascoe @benizao.bsky.social · 28/08/2026
🧫 In 1886, Theodor Escherich was studying bacteria from children with diarrhoea. Among the organisms he saw were strange, curved bacteria. He could see them under the microscope. But he couldn't grow them. It would take almost a century before we understood quite how important they were. 🧵
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Prof Jenny Rohn @jennyrohn.bsky.social · 29/08/2026
Cool study – #Mtb is notoriously slow growing, but inside macrophages, a subpopulation replicates fast and in doing so, actually evade #antibiotics better than the slow-growers - which is counter-intuitive (multiple theories discussed) #MicroSky #Tuberculosis #Tb www.nature.com/articles/s41...
nature.com
Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment - Nature Communications
The slow growth displayed by Mycobacterium tuberculosis has been historically associated with pathogen’s persistence and drug tolerance. Unexpectedly, here the authors identify a rare subpopulation of...
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Anthony M. Bonacolta @ambonacolta.bsky.social · 31/08/2026
My final PhD chapter is now published in Microbiome (@microbiomej.bsky.social)! Using metabarcoding, photochemical measurements, and the first scRNAseq of a bleaching coral, we examined the microbial ecology of coral bleaching at the single-cell level! 🪸🔥 #CoralReefs 🔗 rdcu.be/zWHQ92WqZQUa
link.springer.com
Single-cell ecology of coral-algal symbiosis breakdown - Microbiome
Background The symbiosis between corals and dinoflagellate algae is disrupted by heat stress, leading to bleaching and subsequent coral mortality, devastating reef habitats. Despite its planetary-scal...
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Evgenii Protasov @evgenii-protasov.bsky.social · 01/09/2026
Rethinking the origin of life at seafloor hydrothermal vents #evolution #OriginOfLife #MicroSky @pnas.org www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Edel Pérez-López 🇨🇦 @edelplopez.bsky.social · 31/07/2026
🚨🪲🧬🦠 We have a new preprint out! Link: doi.org/10.64898/202... Insects and microbes are more connected than we realize. Some insects owe part of their ability to feed on plants to genes acquired from bacteria millions of years ago 🤯 See what we found about glycoside hydrolases in leafhoppers.
representation of the study
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Teresa O'Meara @teresaomeara.bsky.social · 29/07/2026
Bacteriology-Focused Assistant Professor Position in Microbiology and Immunology at the University of Michigan Application deadline: August 15, 2026 Come be my colleague!
Bacteriology-Focused Assistant Professor Position in Microbiology and Immunology at the University of Michigan

Application deadline: August 15, 2026

Applicants are requested to send
1) A cover letter (up to 1 page)
2) A CV
3) A description of research interests and goals (up to 2 pages)
4) A description of teaching experience and philosophy (up to 1 page)
5) Contact information including email to solicit 3 letters of recommendation.
Application materials should be combined into one PDF and addressed to the department chair, Dr. Bethany Moore, and sent via email to Sheryl Smith - sherylhs@umich.edu
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Jacquelyn Gill @jacquelyngill.bsky.social · 28/07/2026
My alma mater (College of the Atlantic) is hiring faculty in Field Ecology, Agroecology, and Chemistry. If you're looking for a very cool small liberal arts college on the coast of Maine with a strong environmental focus, check it out (happy to answer questions!): www.coa.edu/human-resour...
coa.edu
Career Opportunities | College of the Atlantic
Career opportunities at the College of the Atlantic in Bar Harbor Maine.
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Carl T. Bergstrom @carlbergstrom.com · 21/07/2026
1. We—@eduede.bsky.social, @mjcrockett.bsky.social, Kevin Gross, and I—have a new preprint on the arXiv today, based on ideas that emerged during an @sfiscience.bsky.social workshop in November 2024: The unintended consequences of large language models as a labor-augmenting technology in science.
arxiv.org
The unintended consequences of large language models as a labor-augmenting technology in science
As a labor-augmenting technology, large language models (LLMs) have the potential to accelerate scientific activity across the research pipeline. But even if LLMs perform on par with human experts at ...
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realkarlklose.bsky.social @realkarlklose.bsky.social · 14/05/2026
Vibriophiles! Achtung! Come to Berlin Sept 13-16 to learn the latest about your favorite bacteria. Great speakers, great venue, great topics, great location (home of Robert Koch). Oral abstract deadline June 15. Please share. @asm.org @rki-de.bsky.social #Vibrio26 #VIS
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Wiep Klaas Smits (ExpBac/CMAT) @smitslab.bsky.social · 15/05/2026
Development and Evaluation of Exosporium-Anchored Bioluminescent and Fluorescent Reporters for Tracking Clostridioides difficile Spores Formed In Vivo | ACS Synthetic Biology pubs.acs.org/doi/10.1021/... #teamluciferase
pubs.acs.org
Development and Evaluation of Exosporium-Anchored Bioluminescent and Fluorescent Reporters for Tracking Clostridioides difficile Spores Formed In Vivo
Clostridioides difficile is an anaerobic spore-forming pathogen and a major cause of hospital-acquired and antibiotic-associated colitis. C. difficile spores are key for persistence and transmission o...
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Amelia Randich @ameliarandich.bsky.social · 27/04/2026
Just don’t call it “death phase” 🙃
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Asher Leeks @asherleeks.bsky.social · 14/04/2026
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
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Ben Engel @cellarchlab.com · 14/04/2026
Across scales from cells🦠 to atoms⚛️ – We reveal how anaerobic #bacteria break down very stable aromatic compounds found e.g. in oil spills 🛢️ #Bioremediation #TeamTomo 🧪 🧶🧬 🔬 Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 14/04/2026
My latest for @sciam.bsky.social is all about the real biology, ecology, and climate science that is used to create the world of Pokémon, and how scientists use it to teach science in the real world. This is just about the most fun I’ve ever had interviewing anyone, and I hope you enjoy! 🧪🌎
scientificamerican.com
The Pokémon universe goes hard on ecology and climate science
The Pokémon franchise, including its recent game Pokémon Pokopia, is inspired by real animals and their ecology. It’s no surprise that so many scientists love to try and “catch ’em all”
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Vaughn Cooper @vscooper.micropopbio.org · 13/04/2026
🆒 new pub! Rapid evolution of Klebsiella pneumoniae biofilms in vitro -> adaptations selected during infection by @gretazabo.bsky.social & Linus Sandegren *hypermucoidy evolves via 📈c-di-GMP, overlaps w/ mutations in UTI and wound isolates. *pleasure to advise this! www.nature.com/articles/s41...
nature.com
Rapid evolution of Klebsiella pneumoniae biofilms in vitro delineates adaptive changes selected during infection - Nature Communications
Biofilm formation on implanted medical devices facilitates infection by the pathogen Klebsiella pneumoniae. Here, Zaborskytė et al. use experimental evolution to show that the bacteria rapidly evolve ...
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Tominaga K. (tomiken) @pacyc184.bsky.social · 08/04/2026
Molecular kinetics dictate population dynamics in CRISPR-based plasmid defense | PNAS www.pnas.org/doi/10.1073/pnas.25254…
pnas.org
Molecular kinetics dictate population dynamics in CRISPR-based plasmid defense | PNAS
Understanding and manipulating the spread of mobile genetic elements represents a great challenge with potential benefits across synthetic biology,...
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Eduardo Rocha @epcrocha.bsky.social · 08/04/2026
Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...
nature.com
Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system - Nature Communications
It remains unclear how viral genomes remain relatively stable over time, given the rapid co-evolution seen within hosts. Here, authors explore complex marine phage-bacteria dynamics using over 1000 ph...
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Harmit Singh Malik @harmitmalik.bsky.social · 07/04/2026
A star scientist showed that better genetics lessons could reduce racism. It was the death knell for his career The loss of Brian Donovan’s grants and job speak volumes about federal funding priorities — and academia www.statnews.com/2026/04/07/b...
statnews.com
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Nature Microbiology @natmicrobiol.nature.com · 07/04/2026
Out Now! Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae #MicroSky
go.nature.com
Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae
Nature Microbiology, Published online: 07 April 2026; doi:10.1038/s41564-026-02322-6Sequential peptidoglycan carboxylase activity of DacA and DacB generates a local peptidoglycan signature that recruits MapZ and establishes the division site at the Streptococcus pneumoniae cell equator.
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Katie Mack @astrokatie.com · 02/04/2026
"The real threat is a slow, comfortable drift toward not understanding what you're doing. Not a dramatic collapse. Not Skynet. Just a generation of researchers who can produce results but can't produce understanding."
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Diez Lab @ TU Dresden @stefandiezlab.bsky.social · 02/04/2026
🥳 Excited to share our #diatom work out in @pnas.org. In a great collaboration with @nic-poulsen.bsky.social and @ulrichschwarz.bsky.social we show that diatoms modulate the curvature of their paths by dynamic switching of their cell–substrate contact sites. doi.org/10.1073/pnas.2506122123
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Vivek Mutalik @vivekmutalik.bsky.social · 03/04/2026
📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.
Phage receptor prediction from genome sequencing alone. Bacterial receptor (blue) interacting with phage proteins (purple) is shown here
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Martin Thanbichler @thanbichlerlab.bsky.social · 03/04/2026
Now available as a Version of Record. Thanks a lot again to everyone involved in this project! doi.org/10.7554/eLif...
doi.org
Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in Caulobacter crescentus
Peptidoglycan recycling is essential for proper cell growth and intrinsic ampicillin resistance in Caulobacter crescentus, highlighting PG recycling enzymes as potential antibacterial targets.
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Nat Clarke @natclarke.bsky.social · 01/04/2026
I'm hiring! I have 2 open positions: 🔬 Postdoc 🧪 Research associate We study how animal multicellularity evolved by exploring the molecular logic of cell adhesion using cell biology, 'omics, and tool-building in non-model organisms. Come join us! Details and application links 👇 Please repost
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Amelia Randich @ameliarandich.bsky.social · 27/03/2026
Congrats!
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