For ten years, baltic (Backronymed Adaptable Lightweight Tree vIsualization Code) has been used to make annotated phylogeny figures in molecular epidemiology, including during the West African Ebola e...

Human interferon-β (IFN-β), a type I IFN, is critical for effective innate immunity and is also an approved disease-modifying therapeutic. While genetic variations in several components of the type I ...

Human interferon-β (IFN-β), a type I IFN, is critical for effective innate immunity and is also an approved disease-modifying therapeutic. While genetic variations in several components of the type I ...

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We study how host alternative splicing shapes the outcome of influenza virus infection — from cryptic isoforms that antagonize the polymerase to the ANP32 proteins that support it.

Since late 2021, highly pathogenic avian influenza viruses (HPAI) of the H5 subtype clade 2.3.4.4b have spread across the Americas, devastating wildlife, agricultural animals, and resulting in dozens ...

Staffers complain that Salk allowed circadian rhythms researcher Satchidananda Panda to depart quietly, while the allegations and findings remain under wraps

López and colleagues review recent evidence of RNA virus persistence and the associated consequences in terms of post-acute sequelae or chronic inflammatory syndromes.

Gutierrez et al. show that cholera toxin induces epithelial LDHA-dependent L-lactate production in the small intestine, creating a nutrient niche that Vibrio cholerae exploits through LldD-mediated L-...

Influenza A is a major human pathogen, which poses risks through both the continuous circulation of “seasonal” influenza viruses (H1N1 and H3N2 subtypes) as well as the emergence of novel pandemic str...

PhD Project - FULLY FUNDED PhD - Visualising avian influenza virus tropism and co-infection in avian hosts at University of Glasgow, listed on FindAPhD.com

Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...

Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Quitting projects in science is hard, but we should be doing a lot more of it.

Cardiac complications are among the most common and severe extrapulmonary manifestations of influenza virus infection, yet they are rarely recapitulated in mouse models without immunodeficiency. We fo...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...

Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...