Coding agents have made data analysis far easier to produce. The hard part now is verifying what comes out. Here’s the scaffolding I built to help.

The mechanical process of cell division exerts powerful, if microscopic, forces. How do the molecular machines that power it manage the strain?

Computational biology is in a period of upheaval that is both exhilarating and terrifying.

Mon, Mar 23, 2026 We’re happy to announce the release of napari 0.7.0! napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing…

Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.

We are very pleased to announce that this year’s Waddington medal winner is James Briscoe. His fundamental discoveries have helped shape our understanding of of how morphogens work, and he has played ...

Cellular responses to stimuli can involve learned behaviors through memory formation. Here, the authors show that cancer cells encode gene expression into cellular memories during therapy resistance v...

Live molecular-scale imaging in fly embryos shows that a single RNA Polymerase II cluster stays bound to active genes during transcription. Cluster formation requires initiation, and intensity represe...

Taking a radical new approach to the publication process resulted in eLife losing its impact factor, but authors, reviewers, editors and funders support the journal and its efforts to reform scientifi...

Computational biology is in a period of upheaval that is both exhilarating and terrifying.

In defense of the role of theory in innovation

The original wooden jigsaw puzzle maker. Established in 2005, all of our 1000+ puzzles are handmade in Boulder, CO with exquisite quality & craftsmanship. Full of odd-shaped "whimsy" pieces, our woode...

In defense of the role of theory in innovation

Quitting projects in science is hard, but we should be doing a lot more of it.

Enhancers control tissue-specific gene expression across metazoans. Although deep learning has enabled enhancer prediction and design in mammalian cell lines and invertebrate systems, it remains uncle...

Deep learning models that predict functional genomic measurements from DNA sequence are powerful tools for deciphering the genetic regulatory code. Existing methods trade off between input sequence le...

To what extent regeneration recapitulates embryonic development is a longstanding question. Here, they show that embryonic gene modules are re-used, rewired, and interconnected to specific injury-indu...

Benzinger et al. develop a chemo-optogenetic system for precise spatiotemporal control of morphogen production in vitro. Using light-controlled Sonic hedgehog expression, they recapitulate neural tube...