We study how host alternative splicing shapes the outcome of influenza virus infection — from cryptic isoforms that antagonize the polymerase to the ANP32 proteins that support it.

Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...

Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.

Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.

With encouragement from the Journal of Bacteriology Editor in Chief, George O’Toole, I have written this short essay in a style different than Journal of Bacteriology articles on model organisms. It i...

Quantitative flow virometry assay to measure the shape of viral particles under various conditions reveals that influenza virus infections dynamically tune shape distribution of progeny particles depe...

Cell-to-cell heterogeneity is a common feature of viral infection that can generate enormous complexity, complicating understanding of infection progression and interpretation of differences between v...

Influenza A virus (IAV) non-canonical replication products can be bound by various host pathogen sensors, including retinoic acid-inducible gene I (RIG-I). However, it is not clear why non-canonical I...

The 44th Annual Meeting of the American Society for Virology! Dates: July 14 – 17, 2025 (Monday – Thursday) Palais des congrès de Montréal Host: McGill University *TEACHER TRAVEL GRANTS: Applications…