Little Lab Coats Podcast · Episode

An overarching goal in microbiome research is to understand how the complex communities in our bodies contribute to health and disease, and ultimately, we aim to leverage and control these communities to promote health. To continue advancing this work, we need conceptual frameworks that aid in understanding the relationships between us and our microbiota. Conceptual frameworks can ensure that we avoid doing our science in silos by unifying work across disciplines, and they can help form hypotheses and questions for future research. In human microbiome research, there have been various conceptual frameworks that have advanced our science (1–4). In this perspective, we highlight the symbiosis framework and definitions in connection to microbiome research, with the hope that adoption of this framework will advance our ability to study the human microbiome.

Marker-gene microbiome surveys systematically under-sample rare taxa, causing alpha diversity metrics to reflect dominance rather than true richness. This conceptual mismatch can lead to misleading e...

Egan et al. report the discovery of a new trophic interaction in nature whereby a parasitic plant attacks multiple species of insects that manipulate plant tissue when the two co-occur on a shared pri...

Abstract. Environmental pollutants can profoundly influence host-associated microbiomes, with cascading effects on host health and susceptibility to diseas

Here, the authors identify widespread disease associations of gut archaea, particularly in colorectal cancer, with further experiments revealing Methanobrevibacter smithii cooperation with cancer-asso...

Herbivorous insects can shape the epidemiology of disease in plants by vectoring numerous phytopathogens. While the consequences of infection are often well-characterized in the host plant, the extent...

Abstract. The gut microbiome plays a fundamental role in host ecophysiology. Numerous studies have examined microbiome composition and functionality to und

The study shows that nitrogenase enzymes have maintained stable isotope signatures over billions of years, revealing how ancient microbes shaped Earth’s nitrogen cycle and offering a new experimental ...

Oceans cover over 70% of the earth’s surface and house a dizzying array of organisms, including five species of the peppercorn-sized ocean-skater Halobates, which live exclusively at the ocean surface...

Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to ...

Mammals have developed some unusual eating habits over the past 100 million years, but a new study has uncovered the surprising lengths to which some have gone to satisfy one of the more peculiar—a ta...

Active solids combine internal active driving with elasticity to realize states with nonequilibrium mechanics and autonomous motion. They are often studied in overdamped settings, e.g., in soft materi...

Viruses are the most abundant biological entities on Earth and play central roles in shaping microbiomes and influencing ecosystem functions. Yet, most viral genes remain uncharacterized, comprising w...

dplyr but make it bussin fr fr no cap. Contribute to hadley/genzplyr development by creating an account on GitHub.

A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell types and widespread co-expres...

Abstract. Microbes coordinate homeostasis in host-associated and environmental ecosystems alike, but the connectivity of these biomes is seldom considered.

Nature Communications - Here, the authors present evidence that the gut microbiome alone, without changes in the host genome, can shape how animals respond to selection, identifying a bacterium and...

Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

Microbial communities play critical roles in ecosystem functioning across a wide range of environmental conditions. The physiological stress imposed by temperature, pH and resource levels can shape t...

eLife has announced a policy which enables authors, editors and reviewers to retroactively change their name in published papers and accompanying decision letters.

Transgender and gender nonconforming (TGnC) people are a primary target of the Trump administration. Multiple executive orders seek to erase TGnC protections; mandate denial of gender identity; and ba...

Through two grassroots efforts, more than 80 op eds have been published in news outlets across the country

MIT - Postdoctoral Associate - Cambridge MA 02139