We are excited to announce and provide RSVP details for the next International Soil Virus Conference that will be held in Saint Loup Lamairé, France on June 16 – 18, 2026. The aim of the conference…

On Saturday, May 2nd the University of South Florida Marine Science Lab (MSL)… Bella Iannotta needs your support for USF Marine Science: Fire Recovery Support

Viruses found in peatlands could play a more important role in carbon storage than previously thought and become indicators of ecosystem health, a study says.

Viruses are omnipresent and the most abundant biological entities on the planet. They play a critical role in shaping the ecology and evolution of all life forms. This chapter provides methods to perf...

Abstract. Estuaries are highly productive ecosystems where microbial communities drive nutrient and carbon cycling, supporting complex food webs. With inte

Metagenomics shows that viral diversity and community structure are shaped by geography and ecosystem health status, positioning viruses as unexpected players in peatland restoration.

Abstract. Viruses are ubiquitous in all environments and impact host metabolism, evolution, and ecology, although our knowledge of their biodiversity is st

Viruses are the most abundant biological entities on Earth and play central roles in shaping microbiomes and influencing ecosystem functions. Yet, most viral genes remain uncharacterized, comprising w...

Viruses are key players in diverse ecosystems, but studying their impacts is technically and taxonomically challenging. Taxonomic complexities derive from undersampling, diverse DNA and RNA genomes wi...

From the human gut to the deep ocean, diverse microbial communities underpin essential ecosystem processes. Limited understanding of the dynamics and …

This Perspective discusses virus-encoded auxiliary metabolic genes and provides a framework for the biological interpretation of these genes.

Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents. Here we introduce Phold, an annotation framework utilis...

Accurate genome annotation is fundamental to decoding viral diversity and understanding bacteriophage biology; yet, the majority of bacteriophage genes remain functionally uncharacterised. Bacteriopha...

Soils harbor diverse microbial communities crucial for ecosystem functioning, but poor genomic representation of many uncultured soil microorganisms limits the utility of existing databases to address...

Nature Reviews Genetics, Published online: 21 July 2025; doi:10.1038/s41576-025-00871-wIn this Review, Roux and Coclet outline current viromics approaches and discuss how they have contributed to our growing understanding of viral genomic diversity, focusing on uncultivated viruses of microorganisms.

An abundance of microbial genomes have been sequenced in the past two decades. For fundamental comparative genomic investigations, where the goal is to determine the major gain and loss events shaping...

In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.

Understanding host-range determinants in temperate bacteriophages is critical for elucidating phage-host co-evolution and advancing phage therapies. We analysed 3,900 Klebsiella genomes from diverse e...

Viruses are pivotal players in deep-sea hydrothermal vents, shaping microbiomes by preying on key hosts. Through a global-scale analysis of vent viruses and their interactions, this study reveals that...

We unlock the potential encoded in phage metagenomes to engineer phages to change host range and kill pathogenic bacteria.

On April 14, 2025, CLS Chair Jo Handelsman and Exec Director Adrienne Hallett sent a letter outlining the tremendous consequences of terminating research and asking that it be reinstated.

Young researchers are choosing between staying in science and staying in the United States.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Abstract. Many universally and conditionally important genes are genomically aggregated within clusters. Here, we introduce fai and zol, which together ena

Three different studies in this issue use metagenomics to study the bacterial and viral dynamics of freshwater microbiomes, highlighting the ecological and environmental drivers of these ecosystems.