Już po raz dwudziesty pierwszy Miasto przyznało nagrody za najlepsze prace doktorskie i magisterskie obronione na poznańskich uczelniach i w instytucjach naukowych. W tym roku wyróżnienia odebrało 13 ...

Schärfen et al. develop a method to measure the structure of nascent RNAs during their synthesis by RNA polymerases. Base pairing occurs rapidly in cells, revealing the strong regulatory potential of ...

Myelin deficiency in the central nervous system leads to severe neurological dysfunctions. Sztachera et al. probe RNA-protein interactions in the myelin-deficient mouse brain in a high-throughput mann...

Approaches are needed to explore regulatory RNA motifs in plants. An interpretable RNA foundation model is developed, trained on thousands of plant transcriptomes, which achieves superior performance ...

New1 is a homologue of the essential yeast translation elongation factor eEF3. Lack of New1 has previously been shown to induce queueing of ribosomes upstream of the stop codon on mRNAs encoding speci...

Dimethyl sulfate (DMS) chemical mapping is widely used for probing RNA structure, with low reactivity interpreted as Watson-Crick (WC) base pairs and high reactivity as unpaired nucleotides. Despite i...

RNA begins to fold as the nascent transcript emerges from a transcribing RNA polymerase. Here, the authors develop a concise method for mapping RNA folding pathways that couples in vitro transcription...

Abstract. Two-dimensional drawing of nucleic acid structures, particularly RNA structures, is fundamental to the communication of nucleic acids research. H

RhoFold+ is an end-to-end language model-based deep learning method to predict RNA three-dimensional structures of single-chain RNAs from sequences.