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Matt Simon

@mattdsimon.bsky.social

532 followers 583 following 0 posts

Chemical biologist studying chromatin & RNA biology at Yale University.

Reposted by Matt Simon

Yale MB&B @yalembb.bsky.social · 26/11/2025

We are excited to announce a tenure-track or tenured faculty position in Computational Biophysics and Biochemistry, exploring the intricate molecular and cellular processes and the complex interactions of their macromolecular components! apply.interfolio.com/177120

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Reposted by Matt Simon

Lisa Racki @lisaracki.bsky.social · 05/04/2025

There is still time to submit an abstract - join us in Nashville!

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Reposted by Matt Simon

Leo Schärfen @leoschaerfen.bsky.social · 26/03/2025

Here is our paper showing in vivo folding of nascent RNA right after synthesis, published now in @cp-molcell.bsky.social! With @karlaneugebauer.bsky.social, @isaac-vock.bsky.social, @mattdsimon.bsky.social www.cell.com/molecular-ce...

cell.com

Rapid folding of nascent RNA regulates eukaryotic RNA biogenesis

Schärfen et al. develop a method to measure the structure of nascent RNAs during their synthesis by RNA polymerases. Base pairing occurs rapidly in cells, revealing the strong regulatory potential of ...

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Reposted by Matt Simon

Science Friday @scifri.bsky.social · 04/03/2025

Are you a scientist or student heading to a @standupforscience.bsky.social ‬rally this Friday? We want to hear from you. Tell us about yourself and why you’re going, how far you’re traveling, why you’re fired up, and whether there will be car snacks. Call or text us at (646) 767-6532.

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Reposted by Matt Simon

Karla Neugebauer @karlaneugebauer.bsky.social · 27/11/2024

We are happy to share the development of Co-transcriptional Structure Tracking by @leoschaerfen.bsky.social, which measures RNA structure formation during its synthesis in vivo. We are excited to discover the activity of helicases on nascent rRNA! www.biorxiv.org/content/10.1...

biorxiv.org

Rapid folding of nascent RNA regulates eukaryotic RNA biogenesis

An RNA′s catalytic, regulatory, or coding potential depends on RNA structure formation. Because base pairing occurs during transcription, early structural states can govern RNA processing events and d...

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