About the team/job We are recruiting a Project Leader to spearhead the development of the RNAcentral and Rfam databases. Rfam and RNAcentral are key resources for RNA Biology that serve tens of thousa...

About the team/job We are recruiting a Project Leader to spearhead the development of the RNAcentral and Rfam databases. Rfam and RNAcentral are key resources for RNA Biology that serve tens of thousa...

AbstractMotivation. Whole Genome and Proteome Alignments, represented by the Multiple Alignment File (MAF) format, have become a standard approach in compa

Abstract. Small molecule chemical probes that covalently bond atoms of flexible nucleotides are widely employed in RNA structure determination. Atomistic m

Recently, de novo variants in an 18 nucleotide region in the centre of RNU4-2 were shown to cause ReNU syndrome, a syndromic neurodevelopmental disorder (NDD) that is predicted to affect tens of thous...

AbstractMotivation. DNA sequence alignment, an important genomic task, involves assigning short DNA reads to the most probable locations on an extensive re

Abstract. Synthetic RNA devices are engineered to control gene expression and offer great potential in both biotechnology and clinical applications. Here,

Abstract. Micromix is a flexible web platform for sharing and integrating microbial omics data, including RNA sequencing and transposon-insertion sequencin

Specialized RNA modification sequencing techniques are helping to uncover how dysregulation of RNA modification leads to disease. This Review discusses how technical artefacts can cause false negative...

Small noncoding RNAs (smRNAs) play critical roles in regulating various cellular processes, including development, stress response, and disease pathogenesis. However, functional characterization of sm...

R2DT: A comprehensive platform for visualising RNA secondary structure Anton I. Petrov Riboscope Ltd Jan 23rd, 2025 · Cambridge RNA Club 1 1

Myriad families of natural RNAs have been proposed, but not yet experimentally shown, to form biologically important structures. Here we report three-dimensional structures of three large ornate bacte...

Abstract. Two-dimensional drawing of nucleic acid structures, particularly RNA structures, is fundamental to the communication of nucleic acids research. H