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Julia M. Brown

@viraljules.bsky.social
305 followers 493 following 9 posts

(mostly) marine microbial and viral ecology via all the 'omics Mainer from away check out my lab webpage at juliambrown.github.io

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Reposted by Julia M. Brown
Maya Voichek @mayavoichek.bsky.social · 24/09/2026
Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)
AI-generated illustration of the soma-to-germline transmission of retrotransposons described in our work
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Bigelow Laboratory for Ocean Sciences @bigelowlab.bsky.social · 01/09/2026
Bigelow Laboratory for Ocean Sciences is excited to announce new leadership and a bold vision for the future of the Single Cell Genomics Center (SCGC). SRSs Nicole Poulton and Julia Brown are now jointly leading the state-of-the-art facility. www.bigelow.org/news/articles/2026-…
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Cameron Thrash @jcamthrash.bsky.social · 27/08/2026
Single-cell-resolved frequency and modes of phage interactions with prokaryoplankton in the tropical surface ocean www.biorxiv.org/content/10.6... #jcampubs 🌊
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Julia M. Brown @viraljules.bsky.social · 27/08/2026
Preprint is out! Documenting virus interactions within individual cells from the GORG-Tropics collection.
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Julia M. Brown @viraljules.bsky.social · 29/07/2026
Check out the conversation I had with Kate Dickerson of the Maine Discovery Museum. A fun conversation about viruses, career, research "cruises", foundational research and more.
maine-science-podcast.simplecast.com
Julia Brown | Maine Science Podcast
A conversation with Julia Brown, Senior Research Scientist at Bigelow Laboratory of Ocean Sciences
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Reposted by Julia M. Brown
Solid Evidence @solidevidence.bsky.social · 07/03/2026
Happy to report that we submitted a new manuscript this week. The manuscript is abour our work untargeting wastewater sequencing as a technique for monitoring viral pathogens from wastewater. @lennijusten.bsky.social 1/ medrxiv.org/cgi/content/...
medrxiv.org
Deep untargeted wastewater metagenomic sequencing from sewersheds across the United States
Wastewater monitoring enables non-invasive, population-scale tracking of community infections independent of healthcare-seeking behavior and clinical diagnosis. Metagenomic sequencing extends this cap...
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Nature Microbiology @natmicrobiol.nature.com · 16/01/2026
Out Now! A phage protein screen identifies triggers of the bacterial innate immune system #MicroSky
go.nature.com
A phage protein screen identifies triggers of the bacterial innate immune system
Nature Microbiology, Published online: 16 January 2026; doi:10.1038/s41564-025-02239-6A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.
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BejaLabTechnion @bejalab.bsky.social · 17/01/2026
Viral theft of light: A cyanophage protein dismantles cyanobacterial photosynthesis to accelerate infection www.cell.com/cell-host-mi...
cell.com
Viral theft of light: A cyanophage protein dismantles cyanobacterial photosynthesis to accelerate infection
Auxiliary metabolic genes, acquired by cyanobacterial viruses (cyanophages) from their hosts, are thought to manipulate host metabolism during infection. A recent study by Nadel et al. performed in vi...
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Marilena Heitger @marinelena.bsky.social · 12/01/2026
Very happy that our paper was published in Limnology & Oceanography #ASLO_LO Huge shoutout to my co-authors🫰 & big thanks to reviewers and editors! May the year keep up this energy 🙌 @microbialoceanv.bsky.social @aslo.org @davehambright.bsky.social aslopubs.onlinelibrary.wiley.com/doi/10.1002/...
aslopubs.onlinelibrary.wiley.com
Major contribution of particle‐associated microbes to deep‐sea organic carbon degradation
The biological carbon pump mediates the export of particulate organic carbon from the euphotic zone to the deep ocean, where it provides the base of the food web. Although deep-sea microbial metaboli...
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Clara Torres-Barceló @clara-inrae.bsky.social · 14/01/2026
#microsky #phagesky #phage At last! Great to see this one out: journals.plos.org/plospathogen... Here, we discovered a nested phage-bacteria network despite their high genetic and ecological diversity. Kudos to everyone involved, especially @chloe-feltin.bsky.social ! @phimresearch.bsky.social
journals.plos.org
Ecological ubiquity and phylogeny drive nestedness in phages–bacteria networks and shape the bacterial defensome
Author summary Viruses that infect bacteria, known as phages, are part of microbial communities and influence the abundance, diversity, and traits of their hosts. In an agriculture-related context, th...
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Beate Kraft @beatekraft.bsky.social · 10/11/2025
Please apply if you are interested in marine biogeochemistry and microbial dark oxygen production. Deadline: November 17th.
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Ramunas Stepanauskas @rstepanauskas.bsky.social · 07/09/2025
I’m excited to share our effort to obtain one of the first estimates of the net rate, in physical time, of lateral gene transfer (LGT) – nature’s own genetic engineering - across a complex, global microbiome: doi.org/10.1093/isme...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 05/09/2025
Phage defence-system abundances vary across environments and increase with viral density Phil. Trans. R. Soc. B by @seanmeaden.bsky.social, Edze Westra and @peterfineran.bsky.social royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org
Phage defence-system abundances vary across environments and increase with viral density | Philosophical Transactions of the Royal Society B: Biological Sciences
The defence systems bacteria use to protect themselves from their viruses are mechanistically and genetically diverse. Yet the ecological conditions that predict when defences are selected for remain ...
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Leo Martins (he/him) @leomrtns.bsky.social · 22/08/2025
very nice, it's a natural spike-in! I wonder what are the GDPR implications, though, of sharing human reads. I guess participants now will be asked to consent to their genomic data being shared.
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Joe Zackular @joeyzacks.bsky.social · 20/08/2025
Happy to team up with @microbe-enjoyer.bsky.social to highlight fantastic work by @gibbological.bsky.social, Alex Carr, and colleagues using community scale metabolic models to predict risk for C. difficile colonization! See the initial study here: www.cell.com/cell-systems...
cell.com
Personalized Clostridioides difficile colonization risk prediction and probiotic therapy assessment in the human gut
Carr et al. show how microbial community-scale metabolic models (MCMMs) predict personalized Clostridioides difficile colonization risk and probiotic efficacy. MCMMs reveal key metabolic strategies ex...
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George Bouras @gbouras13.bsky.social · 08/08/2025
Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation #phagesky 1/n www.biorxiv.org/content/10.1...
biorxiv.org
Protein Structure Informed Bacteriophage Genome Annotation with Phold
Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents. Here we introduce Phold, an annotation framework utilis...
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Mya Breitbart @viromegirl.bsky.social · 01/08/2025
Do you love phage? I have an opening for a postdoc in my lab at the University of South Florida College of Marine Science (@cmarinescience.bsky.social) looking at interactions between marine phage and iron, which is an important limiting trace metal in the oceans (1/5) 🧵#phagesky 🦠🌊
Electron micrograph of two phage infecting a host cell side-by-side, with hearts between them
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Queralt Tolosa, PhD @queralttolosa.bsky.social · 30/07/2025
𝗕𝗿𝗶𝗻𝗴𝗶𝗻𝗴 𝗣𝗵𝗮𝗴𝗲 𝗟𝘆𝘁𝗶𝗰 𝗖𝘆𝗰𝗹𝗲 𝘁𝗼 𝗟𝗶𝗳𝗲 🦠🧬 Dive into the lytic cycle! A bacteriophage injects DNA, hijacks the host, and rapidly replicates until the bacterium lyses, releasing a new swarm of virulent phages! #blender #3D #cgi #science #research #biology #phage #lyticcycle #bacteria #scicomm #sciart
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Nature Reviews Genetics @natrevgenet.nature.com · 21/07/2025
New online! Viromics approaches for the study of viral diversity and ecology in microbiomes
nature.com
Viromics approaches for the study of viral diversity and ecology in microbiomes
Nature Reviews Genetics, Published online: 21 July 2025; doi:10.1038/s41576-025-00871-wIn this Review, Roux and Coclet outline current viromics approaches and discuss how they have contributed to our growing understanding of viral genomic diversity, focusing on uncultivated viruses of microorganisms.
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Julia M. Brown @viraljules.bsky.social · 17/07/2025
Excited to try this one!
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Nick Record @seascapescience.bsky.social · 11/06/2025
"How Little We've Seen" Imagine measuring an area the size of Houston, then making generalizations about the entire globe. From analysis of Bell et al., that's just what we're doing with the deep seafloor. www.science.org/doi/full/10....
science.org
How little we’ve seen: A visual coverage estimate of the deep seafloor
In decades of deep-sea exploration, humans have observed only 0.001% of the deep seafloor, leaving 66% of planet Earth unseen.
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A. Murat Eren (Meren) @merenbey.bsky.social · 05/06/2025
We have a new 3-year postdoc position in our group at the @hifmb.de to study plasmids and plasmids systems of the marine environment to survey their utility in microbial responses to environmental change. Please see the official job ad here, and spread the word: jobs.awi.de/Vacancies/20...
jobs.awi.de
PostDoc in ecology and evolution of plasmids in polar waters at HIFMB (f/d/m)
Layout AWI HIPP extern, englisch
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Emil Ruff @emilruff.bsky.social · 02/06/2025
Simons Graduate Fellowships in Ecology and Evolution www.simonsfoundation.org/grant/simons... Application Deadline July 31, 2025
simonsfoundation.org
Simons Graduate Fellowships in Ecology and Evolution
The purpose of these awards is to provide support for students entering U.S.-based Ph.D. programs with a plan to perform research in ecology and evolution. While we will consider all projects in ecolo...
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Vivek Mutalik @vivekmutalik.bsky.social · 21/11/2024
#phagesky Some partnerships are always fun!! Excited to share one such 🎉 product w Simon Roux, perspectives on our favorite “atypical” phages, for special issue to celebrate my former mentor Carol Gross @ UCSF Tapping the treasure trove of atypical phages www.sciencedirect.com/science/arti...
sciencedirect.com
Tapping the treasure trove of atypical phages
With advancements in genomics technologies, a vast diversity of ‘atypical’ phages, that is, with single-stranded DNA or RNA genomes, are being uncover…
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Carl Zimmer @carlzimmer.com · 02/05/2025
Time to catch up on the past week’s news about science and medicine in the US. Whew. 1/10
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Matthew Hahn @3rdreviewer.bsky.social · 10/04/2025
Not really my announcement to make--I am but a lesser co-author--but IQ-TREE 3 has just been released! (Most credit to Minh Bui and @roblanfear.bsky.social and their labs) ecoevorxiv.org/repository/v...
ecoevorxiv.org
IQ-TREE 3: Phylogenomic Inference Software using Complex Evolutionary Models
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Cameron Thrash @jcamthrash.bsky.social · 09/04/2025
CoverM is published! CoverM: Read alignment statistics for metagenomics academic.oup.com/bioinformati... #jcampubs
academic.oup.com
CoverM: Read alignment statistics for metagenomics
AbstractSummary. Genome-centric analysis of metagenomic samples is a powerful method for understanding the function of microbial communities. Calculating r
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Rob Edwards @linsalrob.bsky.social · 12/03/2025
Check out this list of awesome #virome tools and be sure to add yours! github.com/shandley/awe... #phagesky #microsky
github.com
GitHub - shandley/awesome-virome: A listing of software, tools and databases useful for virome analysis
A listing of software, tools and databases useful for virome analysis - shandley/awesome-virome
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Luke Hillary @lukehillary.bsky.social · 11/02/2025
We're looking for suggestions on how to update and adapt the Minimum Information about an Uncultured Viral Genome (MIUVIG) reporting standard. What works? What needs updating? Check out the survey forms.gle/DPHvMFe8Gsdj... 🧵
forms.gle
MIUViG Update Survey
Since the development of the Minimum Information about an Uncultured Viral Genome (MIUViG) standard (Roux et al. 2019), there has been an explosion in the number of genomic data generated on unculture...
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Ran Blekhman @blekhman.bsky.social · 27/01/2025
Out now, a comprehensive guide to metagenomics -- from sample collection to data analysis. This primer covers best practices, challenges, and applications in health, agriculture & environment. A roadmap for studying microbial communities 👇 www.nature.com/articles/s43...
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Cameron Thrash @jcamthrash.bsky.social · 28/01/2025
Characteristics of Phages and Their Interactions With Hosts in Anaerobic Reactors enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #jcampubs
enviromicro-journals.onlinelibrary.wiley.com
Characteristics of Phages and Their Interactions With Hosts in Anaerobic Reactors
Diverse and novel phages were recovered from anaerobic fatty acid–fed reactors. Phages linked to hosts in all three functional groups primarily consisted of generalists and temperate species, especia...
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Axel Visel @axelvisel.bsky.social · 17/01/2025
Genomes assembled from #metagenomes (a.k.a. MAGs) are awesome and have revolutionized our ability to study uncultivated microbes ...BUT: they still don't capture a lot of the 🦠 species that are out there New @jgi.doe.gov paper led by Dongying Wu and Natalia Ivanova: www.science.org/doi/10.1126/...
Venn diagram illustrating microbial diversity of bacteria and archaea captured by isolates, metagenome-assembled genomes (MAGs) from NCBI and IMG, and metagenomes from IMG. A large portion of microbial diversity, labeled as 'Microbial Dark Matter,' represents species not captured by isolates or MAGs. Image modified from https://www.science.org/doi/10.1126/sciadv.adq2166
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Phage papers @phagepapers.bsky.social · 01/12/2024
Phage-induced disturbance of a marine sponge microbiome. DOI: 10.1186/s40793-024-00637-7 pubmed.ncbi.nlm.nih.gov/39593141
pubmed.ncbi.nlm.nih.gov
Phage-induced disturbance of a marine sponge microbiome - PubMed
Our findings suggest that sponge microbiome diversity and, by extension, its resilience depend on the maintenance of resident bacterial community members, irrespective of their abundance. Phage-induced disturbances can significantly alter community structure by promoting the growth of opportunistic …
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Rob Lanfear @roblanfear.bsky.social · 26/11/2024
If you had a really nice looking alignment of about thirty 100kb virus genomes and you wanted to find recombination breakpoints, what software/methods would you use? All suggestions, snark, links to papers etc. welcome. Trying to navigate a new field... Please repost! 🧪
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Samuel Aroney @aroneys.bsky.social · 26/11/2024
Excited to share “Bin Chicken”, substantially improving genome recovery through rational metagenomic assembly. Applied to public 🌍 metagenomes, it recovered 24,000 novel species 🦠, including 6 novel phyla. doi.org/10.1101/2024... @wwood @rhysnewell @CMR_QUT 🧵1/6
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Dacks Lab (Evolutionary Cell Biology) @dackslabecb.bsky.social · 25/11/2024
A community consensus paper about a contentious subject like the Last Eukaryotic Common Ancestor does feel very bluesky in late 2024 doesn't it? It was pretty fun to write. Hopefully you'll have fun reading it:) Kudos to @Tom Richards for his writing and cat herding abilities! plos.io/4g0alq4
plos.io
Reconstructing the last common ancestor of all eukaryotes
Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. This Consensus View lays out guidelines to identify the gene repertoire of the Last Eukaryotic Com...
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Rebee @rebee.bsky.social · 22/11/2024
Protein sequencing with nanopores? The latest review on the subject dropped yesterday 🤓 www.nature.com/articles/s44...
nature.com
Single-molecule protein sequencing with nanopores - Nature Reviews Bioengineering
Biological nanopores can be designed for high-sensitivity sequencing of peptides and proteins. This Review discusses different approaches towards nanopore-based protein sequencing, outlining methods t...
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Veit Hornung @v-hornung.bsky.social · 19/11/2024
📢 Postdoc opening! 📢 @soreklab.bsky.social and we are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research in two dynamic fields. Interested? Let’s connect! 👇 www.genzentrum.uni-muenchen.de/career/postd...
genzentrum.uni-muenchen.de
Postdoctoral Position (f/m/x) in Immunology / Biochemistry / Computational Biology - Gene Center Munich - LMU Munich
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Denis Wirtz @deniswirtz.bsky.social · 17/11/2024
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS. For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship). Download freely here: research.jhu.edu/rdt/funding-...
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Katy Brown @thekatybrown.bsky.social · 16/11/2024
I made a quick Starter Pack for scientists working on virus discovery - please reply if you’d like me to add you to the pack (or remove you) or to recommend anyone! #scisky go.bsky.app/HK1wxRb
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Jim Shaw @jimshaw.bsky.social · 19/11/2024
I wrote about the backstory of our recently published metagenomic profiler called sylph (www.nature.com/articles/s41...), partially to celebrate the new migration to bluesky Check out the blog here: jim-shaw-bluenote.github.io/blog/2024/de... -- and I apologize in advance for the lack of brevity :)
jim-shaw-bluenote.github.io
Developing sylph - a look into bioinformatics tool development | Jim Shaw
Jim Shaw's academic website.
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Jarrett Byrnes @jebyrnes.bsky.social · 13/11/2024
One week left to apply for this faculty position in marine ecology at UMass Boston! Take a look, and please let me know if you have any questions. Great department, great marine systems, great students! employmentopportunities.umb.edu/boston/en-us... 🧪🌍🌊
employmentopportunities.umb.edu
Page Up - UMass Boston
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Julia M. Brown @viraljules.bsky.social · 30/10/2024
Twitter account's deactivated, it's all blue sky now! I look forward to continuing the conversation.
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Cameron Thrash @jcamthrash.bsky.social · 25/10/2024
Seasonal dynamics and diversity of Antarctic marine viruses reveal a novel viral seascape www.nature.com/articles/s41... #jcampubs 🌊
nature.com
Seasonal dynamics and diversity of Antarctic marine viruses reveal a novel viral seascape - Nature Communications
The study reveals that the Southern Ocean hosts a unique and largely underexplored DNA viral community. It explores the diversity of viral communities infecting all domains of life and their seasonali...
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Terry McGlynn @hormiga.bsky.social · 08/07/2024
A new program from NSF is targeting graduate fellowship money to people who received Honorable Mention on a GRFP within the past three years, who are currently enrolled in grad school in EPSCoR states. here is the solicitation: new.nsf.gov/funding/oppo... and a map of EPSCoR eligible states:
Alabama Alaska Arkansas Deleware Guam Hawaii Iowa Idaho Kansas Kentucky Louisiana Maine Mississippi Montana Nebraska New Hampshire New Mexico North Dakota Nevada Oklahoma Puerto Rico Rhode Island South Carolina South Dakota US Virgin Islands Vermont West Virginia Wyoming
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Nick Record @seascapescience.bsky.social · 11/10/2024
I love maps. This is a hand-drawn map of Allen Island Maine by Rick Donaghue. “Possession of this map by sheep strictly prohibited”
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Steven Biller @stevenbiller.bsky.social · 18/07/2024
Latest from my lab: we show that extracellular vesicles and viral-like particles are distinct vehicles for horizontal gene transfer, differing in DNA capacity and functional content. EVs harbor an incredible diversity of mobile elements! #MicroSky #ViroSky www.researchsquare.com/article/rs-4...
researchsquare.com
Distinct horizontal gene transfer potential of extracellular vesicles versus viral-like particles in marine habitats
Horizontal gene transfer (HGT) is enabled in part through the movement of DNA within two broad groups of small (<0.2 µm), diffusible nanoparticles: extracellular vesicles (EVs) and virus-like parti...
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Ramunas Stepanauskas @rstepanauskas.bsky.social · 15/07/2024
I hope this in-depth comparison of single amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) will help inform data interpretation and experimental design in a broad range of research projects: link.springer.com/article/10.1...
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Julia M. Brown @viraljules.bsky.social · 02/05/2024
Two weeks left on our cruise to the Oxygen Minimum Zone off the coast of Chile... content is coming out! Cameos from Laura Bristow, Osvaldo Ulloa and Chief Scientist Maria Pachiadaki (@microbiaki.bsky.social) www.youtube.com/watch?v=fGi6...
youtube.com
Exploring an Invisible World in the Ocean | Microbes in Oxygen Minimum Zones - Week 1
Oxygen Minimum Zones, or OMZs, are areas in the water column with less oxygen, primarily due to naturally occurring physical and biological processes within ...
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