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Luke Hillary

@lukehillary.bsky.social
642 followers 390 following 35 posts

Genomics & qPCR surveillance of soils, sludge & sewage 🏞️💩😷 | RNA viruses, AMR genes & mobile elements in environmental microbiomes | Research Fellow @bangor.ac.uk | Building the evidence base for wastewater-informed public health in Wales 🏴󠁧󠁢󠁷󠁬󠁳󠁿

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Reposted by Luke Hillary
John Morgan @johnmorgan3.bsky.social · 09/02/2026
UKRI's chief executive said recently that the UK "may wish to explore" paring back its association to the EU's research programme, to make it partial. That would be a "profound strategic error", critics now warn. By @clanicholson.bsky.social www.researchprofessionalnews.com/rr-news-euro...
researchprofessionalnews.com
Any UK plan for partial Horizon association ‘a profound error’ - Research Professional News
Academic leaders warn against UK abandoning participation in collaborative part of EU R&I programme
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Karthik Anantharaman @karthik-a.bsky.social · 12/12/2025
Our paper "Ecosystem health shapes viral ecology in peatland soils" is out in Nature Microbiology! We show that peatland health strongly structures viral communities, shaping virus–host networks, and carbon and nutrient cycling. Please share. www.nature.com/articles/s41... #phagesky #Microsky
nature.com
Ecosystem health shapes viral ecology in peatland soils - Nature Microbiology
Metagenomics shows that viral diversity and community structure are shaped by geography and ecosystem health status, positioning viruses as unexpected players in peatland restoration.
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Reposted by Luke Hillary
Joint Genome Institute @jgi.doe.gov · 10/12/2025
The Metagenome Stability Diagram uses gene markers across ecosystems to understand how environmental conditions constrain metabolic activity in microbiomes. 🖥️🧬🦠 jgi.doe.gov/user-science/science-st…
jgi.doe.gov
Data Discovery Tool Helps Identify Microbial Roles within Metagenomes | Joint Genome Institute
Protein annotations provide insights into environmental tendencies
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Reposted by Luke Hillary
James Kosmopoulos @kosmopoulos.bsky.social · 10/12/2025
Soil viruses are important regulators of ecosystem function, but what are their roles in environments that face long-term degradation and restoration? In our paper published today in Nature Micro, we asked how soil viruses influence peatland recovery, and vice versa. www.nature.com/articles/s41...
nature.com
Ecosystem health shapes viral ecology in peatland soils - Nature Microbiology
Metagenomics shows that viral diversity and community structure are shaped by geography and ecosystem health status, positioning viruses as unexpected players in peatland restoration.
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Luke Hillary @lukehillary.bsky.social · 27/11/2025
📢 New preprint is out on bioRxiv 📢: How much does virome prep influence our view of the human gut virome? Short answer: a lot. Long answer: doi.org/10.1101/2025... Different methods lead to distinct community structures, richness, and major virus-host abundance patterns. 🧵 1/5
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Ashish Malik @ashish-malik.bsky.social · 17/10/2025
PhD opportunity with me at University of Edinburgh linked with Forest Research, funded by E5 DTP. On the microbial mechanisms of soil carbon cycling in tree-planted upland soils. Apply before 14th Dec. Please share with your network. Pic: one of our Scottish sites. e5-dtp.ed.ac.uk/project?item...
An upland landscape in Scotland with trees and open areas.
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Reposted by Luke Hillary
Mya Breitbart @viromegirl.bsky.social · 02/10/2025
We're hiring for several positions (a post-bac researcher in #transcriptomics, a #phage #postdoc, a senior researcher (broad topics) and a graduate student to work on #ciliates) - find info here: www.marine.usf.edu/genomics/app...
marine.usf.edu
Apply - Genomics
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Luke Hillary @lukehillary.bsky.social · 21/09/2025
Love this new paper from @gtrubl.bsky.social and @alexjprobst.bsky.social on the importance of accurate use of terminology in microbial ecology. I’ve seen a lot of use of lysogenic instead of temperate recently so it’s nice to see that distinction being made. doi.org/10.1111/1462...
doi.org
Clarifying Terminology in Microbial Ecology: A Call for Precision in Scientific Communication
The rapid evolution of microbiology as a field of research has led to the introduction of new terminology and the adaptation of existing terms. However, inconsistencies in the use of these terms, inc...
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Luke Hillary @lukehillary.bsky.social · 20/09/2025
🎉Woot woot 🎉Finished a 2 week writing challenge with sending a manuscript off to co-authors/ submitting data to NCBI. Onto the next one 😁
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Reposted by Luke Hillary
Joint Genome Institute @jgi.doe.gov · 10/09/2025
Learn more about EcoFABs in this episode of our #GenomeInsider podcast ⬇️ 🖥️🧬
jgi.doe.gov
Experimenting with EcoFABs for Student Labs - Jill Bouchard & Ying Wang | Joint Genome Institute
This episode, we visit Los Medanos Community College to see EcoFABs in action in Jill Bouchard’s BIO 21 lab course.
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Luke Hillary @lukehillary.bsky.social · 10/09/2025
Fitting that Google has DNA in today’s doodle,the same day Marie Skłodowska-Curie postdoc fellowship proposals are due in 😁🧬
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Reposted by Luke Hillary
Soil Microbial Ecology Group @soilmicrobes.bsky.social · 09/09/2025
📢 We are thrilled to announce the International Soil Virus Conference 2026 in conjunction with the Saint Loup Research Institute. 🗓️ June 16 – 18, 2026 📍 Château de Saint Loup sur Thouet, France 👇 RSVP by October 31st, 2025 #virus #phage #ISVC2026
soilmicrobes.fr
ISVC2026
International Soil Virus Conference 2026! We are excited to announce and provide RSVP details for the next International Soil Virus Conference that will be held in Saint-Loup Lamaire, France on Jun…
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Reposted by Luke Hillary
Dan Sloan @sloanevolab.bsky.social · 08/09/2025
The Department of Biology at Colorado State University is hiring an Assistant Professor in the area of plant-microbe interactions! Please spread the word! jobs.colostate.edu/postings/165...
jobs.colostate.edu
Assistant Professor Plant-Microbe Interactions
We seek a creative, collaborative, and visionary plant biologist to establish an internationally recognized research program at the forefront of plant-microbe interactions aimed at understanding how t...
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Reposted by Luke Hillary
Nature Microbiology @natmicrobiol.nature.com · 08/09/2025
#Perspective A discussion on virus-encoded auxiliary metabolic genes and a framework for the biological interpretation of these genes. #MicroSky 🦠 www.nature.com/articles/s41...
nature.com
A call for caution in the biological interpretation of viral auxiliary metabolic genes - Nature Microbiology
This Perspective discusses virus-encoded auxiliary metabolic genes and provides a framework for the biological interpretation of these genes.
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Luke Hillary @lukehillary.bsky.social · 05/09/2025
Awesome looking review on RNA phage discovery 😁
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Reposted by Luke Hillary
Royal Society Publishing @royalsocietypublishing.org · 05/09/2025
A new theme issue of #PhilTransB examines the evolutionary history of bacterial immune systems, their modes of action, and the patterns how different bacterial immune systems are distributed across different ecosystems. Read: buff.ly/Z4qdxY1
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Reposted by Luke Hillary
Karina Ilchenko @karinailchenko.bsky.social · 03/09/2025
🚨 New preprint! 🧬 𝐏𝐡𝐚𝐠𝐞-𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 (𝐏-𝐏𝐬) are fascinating elements: both 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐞 𝐩𝐡𝐚𝐠𝐞𝐬 and 𝐩𝐥𝐚𝐬𝐦𝐢𝐝𝐬 ➡️ tricky to detect. We present 𝐭𝐲𝐏𝐏𝐢𝐧𝐠 — the first 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐜𝐥𝐚𝐬𝐬𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐭𝐨𝐨𝐥 🛠️designed specifically for P-Ps: ✅ Accurate ✅ Sensitive ✅ Easy to use 📖 www.biorxiv.org/content/10.1...
biorxiv.org
Efficient detection and typing of phage-plasmids
Phage-plasmids are temperate phages that replicate as plasmids during lysogeny. Despite their high diversity, they carry genes similar to phages and plasmids. This leads to gene exchanges, and to the ...
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Reposted by Luke Hillary
Rayan Chikhi @rayanchikhi.bsky.social · 03/09/2025
🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024...
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Luke Hillary @lukehillary.bsky.social · 03/09/2025
It’s life @jgi.doe.gov 🖖 but not as we know it. This symposium looks fascinating! (couldn’t resist making the Trek reference)
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Reposted by Luke Hillary
John Innes Centre @johninnescentre.bsky.social · 29/08/2025
BLOG - Seven ingredients for a Neuroinclusive research organisation In our latest #JICNeurodiversity blog, we reflect on the remarkable impact and success of our BBSRC @ukri.org funded “Understanding, Valuing and Celebrating Neurodiversity” project 🌈🧠 Watch full video: youtu.be/bwUEJju9XQ4?...
youtu.be
Understanding, Valuing and Celebrating Neurodiversity – Impact of our BBSRC Connecting Culture grant
YouTube video by John Innes Centre
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Reposted by Luke Hillary
Applied Microbiology International @amiposts.bsky.social · 01/09/2025
Save the Date: #MMEG2025 is coming to Birmingham! Join us on 15–16 December 2025 for the 31st edition of MMEG. This year's event is your chance to: 🔬 Share your research 🤝 Connect with peers 🦠 Discover the latest in molecular microbial ecology Register now: appliedmicrobiology.org/ems-event-ca...
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Reposted by Luke Hillary
Tominaga K. (tomiken) @pacyc184.bsky.social · 31/08/2025
Highly accurate prophage island detection with PIDE | Genome Biology | Full Text genomebiology.biomedcentral.com/art…
genomebiology.biomedcentral.com
Highly accurate prophage island detection with PIDE - Genome Biology
As important mobile elements in prokaryotes, prophages shape the genomic context of their hosts and regulate the structure of bacterial populations. However, it is challenging to precisely identify prophages through computational methods. Here, we introduce PIDE for identifying prophages from bacterial genomes or metagenome-assembled genomes. PIDE integrates a pre-trained protein language model and gene density clustering algorithm to distinguish prophages. Benchmarking with induced prophage sequencing datasets demonstrates that PIDE pinpoints prophages with precise boundaries. Applying PIDE to 4744 human gut representative genomes reveals 24,467 prophages with widespread functional capacity. PIDE is available at https://github.com/chyghy/PIDE , with model training code at https://zenodo.org/records/16457629 .
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Reposted by Luke Hillary
Nature Biotechnology @natbiotech.nature.com · 27/08/2025
The microbial composition of metagenomes is identified in seconds by profiling against large databases go.nature.com/3BBVqDC rdcu.be/eCbj4
go.nature.com
Rapid species-level metagenome profiling and containment estimation with sylph - Nature Biotechnology
The microbial composition of metagenomes is identified in seconds by profiling against large databases.
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Reposted by Luke Hillary
Ioanna Chatzigiannidou @ioannachatzig.bsky.social · 26/08/2025
Soil is the most diverse microbial ecosystem, which makes microbiome studies with shotgun sequencing extremely tricky! In our last paper @imetascience.bsky.social, we show that co-assembly increases gene and genome recovery tinyurl.com/59t4z8fh #soilmicrobiome #metagenomics
onlinelibrary.wiley.com
Unveiling soil microbial diversity through ultra‐deep short‐read metagenomic sequencing and co‐assembly
By combining ultra-deep short-read shotgun metagenomic sequencing with 5-sample co-assembly across 600 agricultural soil samples, we significantly enhanced the representation and recovery of microbia....
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Reposted by Luke Hillary
Anny Chung (鍾彥儀) @yyachung.bsky.social · 21/08/2025
🍄 UGA Plant Pathology is hiring TT faculty in Mycology/Fungal Biology/Fungal Ecology at the Asst/Assc level! Please pass along this opportunity to anyone you know who may be interested. I'm on the search committee and happy to answer questions. 🍄 www.ugajobsearch.com/postings/445...
ugajobsearch.com
Assistant or Associate Professor - Fungal Biology/Mycology
The Department of Plant Pathology in the College of Agricultural and Environmental Sciences (CAES) at the University of Georgia is recruiting for the position of Assistant or Associate Professor in Fu...
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Reposted by Luke Hillary
Queralt Tolosa, PhD @queralttolosa.bsky.social · 30/07/2025
𝗕𝗿𝗶𝗻𝗴𝗶𝗻𝗴 𝗣𝗵𝗮𝗴𝗲 𝗟𝘆𝘁𝗶𝗰 𝗖𝘆𝗰𝗹𝗲 𝘁𝗼 𝗟𝗶𝗳𝗲 🦠🧬 Dive into the lytic cycle! A bacteriophage injects DNA, hijacks the host, and rapidly replicates until the bacterium lyses, releasing a new swarm of virulent phages! #blender #3D #cgi #science #research #biology #phage #lyticcycle #bacteria #scicomm #sciart
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Mya Breitbart @viromegirl.bsky.social · 01/08/2025
Do you love phage? I have an opening for a postdoc in my lab at the University of South Florida College of Marine Science (@cmarinescience.bsky.social) looking at interactions between marine phage and iron, which is an important limiting trace metal in the oceans (1/5) 🧵#phagesky 🦠🌊
Electron micrograph of two phage infecting a host cell side-by-side, with hearts between them
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Scott McGrath @smcgrath.phd · 22/07/2025
🧪 New research confirms climate change is a primary driver of worsening forest fires. The likelihood of extreme fire weather has doubled since the preindustrial era, contributing to a dramatic increase in burned forest area globally. #Climate #Fires
nytimes.com
Climate Change Is Making Fire Weather Worse for World’s Forests
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Luke Hillary @lukehillary.bsky.social · 22/07/2025
A really great review written by @simrouxvirus.bsky.social and Clement Coclet on the state of the field of viromics and viral ecology. Well worth a look, and provides a solid reading list for those entering the field wanting more background on how it has developed and what tools are available.
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UK Research and Innovation @ukri.org · 18/07/2025
Exciting news: over £59m announced to support the Government’s new compute roadmap. Our investment will support the career development of researchers and innovators, enabling UK-wide capability and access to digital infrastructure. More: www.ukri.org/news/governm... or ⬇️🧵1/
Screenshot of a webpage. Text reads: 'Government and UKRI launch compute roadmap'. Below is an abstract image of data cubes.
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Luke Hillary @lukehillary.bsky.social · 17/07/2025
What a fantastic conference! Great to present my work on soil viral responses to simulated wildfire at #FEMS2025 So many interesting talks and posters.
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Ákos T Kovács @evolvedbiofilm.bsky.social · 16/07/2025
Prophages block cell surface receptors to preserve their viral progeny @nature.com from @themaxwelllab.bsky.social www.nature.com/articles/s41...
nature.com
Prophages block cell surface receptors to preserve their viral progeny - Nature
Zip promotes the accumulation of free phages in bacterial lysogen communities, safeguarding phage progeny.
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Luke Hillary @lukehillary.bsky.social · 15/07/2025
First swag of #FEMS2025 from @novogene-europe.bsky.social 😁
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Luke Hillary @lukehillary.bsky.social · 14/07/2025
See what happens to soil viruses when you set their habitat on fire! #FEMS2025 Super excited to be presenting my work on DNA/ RNA viruses and how they respond to wildfire. Talk is 13:00 on Thursday, Brown 1&2 Massive thanks to @femsmicro.org for supporting my attendance!
Talk title - Fire severity impacts DNA and RNA viral communities in fire-adapted shrubland wildfirepyrocosms
Time and location - 13:00 FEMS Microbial Ecology: Microbial dynamics in a changing world (Brown 1&2)
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Claus Wilke @clauswilke.com · 10/07/2025
AI slows down experienced developers (against their expectations) in a randomized controlled trial of AI coding effectiveness. metr.org/Early_2025_A...
Figure 1: Experts and study participants (experienced open-source contributors) substantially overestimate how much AI assistance will speed up developers—tasks take 19% more time when study
participants can use AI tools like Cursor Pro. See Appendix D for detail on speedup percentage and
confidence interval methodology.
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Balance of the Microverse @microverse.bsky.social · 16/05/2025
🧬 New tool alert: Vclust helps researchers rapidly sort through millions of viral genomes—even fragmented ones. @bedutilh.bsky.social co-developed Vclust, a tool for ultrafast clustering of viral genomes. It's open-source, web-accessible, and just published. 📄 doi.org/10.1038/s415...
doi.org
Ultrafast and accurate sequence alignment and clustering of viral genomes - Nature Methods
Vclust generates fast and accurate estimation of average nucleotide identity for viral genomes, scaling clustering to millions of genomes.
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Luke Hillary @lukehillary.bsky.social · 11/05/2025
Absolutely love the commitment from @rdrpsummit.bsky.social to the hybrid format. Makes a huge difference to widening access to conferences. Huge thanks for the invite to talk about this work on updating the MIUViG reporting standards. More developments on this soon.
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RdRp Summit @rdrpsummit.bsky.social · 08/05/2025
Stoked to have Luke Hillary (@lukehillary.bsky.social) joining us to talk about adapting MIUViG for RNA viruses—huge step for making sense of uncultivated RNA viromes!😍 #RdRpSummit2025 in 3 days!
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Reposted by Luke Hillary
Soil Microbial Ecology Group @soilmicrobes.bsky.social · 13/03/2025
Our perspective on soil virus ecology research is out! Fantastic collab with @christinahazard.bsky.social @karthik-a.bsky.social @lukehillary.bsky.social @urineri.bsky.social @simrouxvirus.bsky.social @gtrubl.bsky.social @KurtWilliams @jeffinerca.bsky.social @graemenicol.bsky.social @JoanneEmerson
sciencedirect.com
Beneath the surface: Unsolved questions in soil virus ecology
Soil virus ecology is an exciting but still nascent field of research in soil microbiology. While there has been a recent surge in soil virus research…
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Amy D Willis @amydwillis.bsky.social · 21/02/2025
The latest from the StatDivLab -- guidance for your #microbiome data analysis with a focus on the #statistics. Planning, deciding, modeling, justifying, communicating, visualizing... "Papers Need Friends" blog post coming shortly.
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Simon Roux @simrouxvirus.bsky.social · 11/02/2025
🚨🚨🚨Updates are coming for the MIUViG standards/checklist 🚨🚨🚨 If you work with uncultivated virus genomes (i.e. from metaG, metaT, etc), have tried to submit these genomes to a database and found some issues/suggestions, or tried to use these data and have comments/thoughts, please share them !!
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Luke Hillary @lukehillary.bsky.social · 11/02/2025
We're looking for suggestions on how to update and adapt the Minimum Information about an Uncultured Viral Genome (MIUVIG) reporting standard. What works? What needs updating? Check out the survey forms.gle/DPHvMFe8Gsdj... 🧵
forms.gle
MIUViG Update Survey
Since the development of the Minimum Information about an Uncultured Viral Genome (MIUViG) standard (Roux et al. 2019), there has been an explosion in the number of genomic data generated on unculture...
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Ran Blekhman @blekhman.bsky.social · 27/01/2025
Out now, a comprehensive guide to metagenomics -- from sample collection to data analysis. This primer covers best practices, challenges, and applications in health, agriculture & environment. A roadmap for studying microbial communities 👇 www.nature.com/articles/s43...
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Luke Hillary @lukehillary.bsky.social · 23/01/2025
😲 www.science.org/content/arti...
science.org
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
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Reposted by Luke Hillary
Jyot Antani @antanij.bsky.social · 19/12/2024
We developed a microscopy-based technique🔬 to measure attachment of viruses #phages to host cells. 🦠 The paper was posted online today: www.pnas.org/doi/10.1073/... #phagesky #microsky
Bright green spots are phages (viruses), bacteria are the faint rods in light blue.
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James McDonald @jamesemcdonald.bsky.social · 17/12/2024
Had a great time with the team at #MMEG2024 and catching up with lab alumnus @lukehillary.bsky.social @marccamb.bsky.social @alejandra1909.bsky.social @sophie-e-powell.bsky.social @alexanderwoodley.bsky.social @g-thomas.bsky.social
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Aude Bernheim @audeber.bsky.social · 16/12/2024
Out in NAR, AntiDefenseFinder & our "systematic" analysis of inhibitors of antiphage systems wt Bondy-Denomy lab led by @ftesson.bsky.social and E. Huiting. Not so "systematic" as very few known, fun stuff on MGE, antidefense islands and cool phages exaptations! academic.oup.com/nar/advance-...
academic.oup.com
Exploring the diversity of anti-defense systems across prokaryotes, phages and mobile genetic elements
Abstract. The co-evolution of prokaryotes, phages and mobile genetic elements (MGEs) has driven the diversification of defense and anti-defense systems ali
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Marine C. Cambon @marccamb.bsky.social · 16/12/2024
It's so nice being back at #MMEG2024 in Southampton finally presenting the results of our study in insect-bacteria interactions @jamesemcdonald.bsky.social @gathomas12.bsky.social
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Luke Hillary @lukehillary.bsky.social · 16/12/2024
MMEG has always been a favourite conference of mine to go to since the first year of my PhD. Great to present some results from my current postdoc on viral community responses to wildfire this year #MMEG2024
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Dr. Sue Ishaq @drsueishaq.bsky.social · 22/11/2024
White paper and perspective published on "Running a queer- and trans-inclusive faculty hiring process"!! Advice for job searches that are better for everyone: writing job adverts + agendas, improving interviews, supporting faculty. Graphics by Callie R. Chappell. sueishaqlab.org/2024/11/22/w...
sueishaqlab.org
White paper and perspective published on “Running a queer- and trans-inclusive faculty hiring process”!!
I’m delighted to announce the public release of a white paper on queer- and trans-inclusive faculty hiring practices, and a perspective piece introducing it!! This is the culmination of month…
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