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Taufik A. Valiante

@tvaliante.bsky.social
237 followers 242 following 14 posts

Neuroscientist, Neurosurgeon, Krembil Brain Institute, CRANIA, MPUTC, BME & ECE University of Toronto. neurontobrainlaboratory.ca kite-uhn.com/crania mpc.utoronto.ca

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Reposted by Taufik A. Valiante
The Onion @theonion.com · 27/09/2026
World's Scientists Admit They Just Don't Like Mice theonion.com/worlds-scientists-admi…
World's Scientists Admit They Just Don't Like Mice
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CorrinaLeeB 🇨🇦 @corrina.sheshed.rocks · 16/08/2026
Canada has officially started building the wall at the U.S. border🇨🇦😂 Budget: a few trees Construction crew: 1 beaver 🦫 Payment: maple syrup 🍁 Sorry for the inconvenience, eh? 😂 #Canada #CanadianHumour #SheShed
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The Transmitter @thetransmitter.bsky.social · 17/07/2026
Nobel laureate Susumu Tonegawa, who pioneered cell-type-specific transgenic mice and the study of engrams, has passed away at the age of 86. By @claudia-lopez.bsky.social www.thetransmitter.org/memory/susum...
thetransmitter.org
In memoriam: Susumu Tonegawa, ‘intellectual giant’
He won the Nobel Prize for his work on immunology and then went on to define the field of learning and memory.
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Tim Behrens @behrenstimb.bsky.social · 27/06/2026
Slightly surprised that @kordinglab.bsky.social are still printing their simulations out on paper to be honest.
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Shervin Safavi @neuroprinciplist.bsky.social · 09/06/2026
1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇
cell.com
Perceptual multistability: a multifaceted window into brain dysfunctions
Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics a...
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Taufik A. Valiante @tvaliante.bsky.social · 24/06/2026
What does a multimodal electrode look like to you? This is what it looks like to us - it’s electrical⚡️, optical 💡 and fluidic💧. Amazing work by Xin Mu, Wesley Sacher and Homeira Moradi Chameh. We also made the cover 🥳! 🔗 to 📄 : www.nature.com/articles/s41...
nature.com
Nanophotonic neural probes for in vivo photostimulation, electrophysiology, and microfluidic delivery - Microsystems & Nanoengineering
Microsystems & Nanoengineering - Nanophotonic neural probes for in vivo photostimulation, electrophysiology, and microfluidic delivery
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Nature @nature.com · 22/06/2026
Nature research paper: A mosaic of whole-body representations on the human precentral gyrus go.nature.com/44k08Ru
go.nature.com
A mosaic of whole-body representations on the human precentral gyrus - Nature
A comprehensive map of the human motor cortex at single-neuron resolution is described.
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Richard Naud @neuronaud.bsky.social · 06/10/2025
How are the fluctuations in electric field organized across the whole brain? We analyzed the 3.4 M samples from the international brain lab using a combination of deep learning and graph theory. We found a surprising structure made of communities and landmarks. doi.org/10.1101/2025...
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tbiba.bsky.social @tbiba.bsky.social · 02/03/2026
I am excited to share my first paper, showing that episodic memory formation is theta rhythmic, is now published in Nature Human Behavior! Check it out here: rdcu.be/e6pzS. Thanks to my PI, Katherine Duncan, and to my collaborators for their support on this journey! Stay tuned for iEEG follow up 🧠
rdcu.be
Episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz
Nature Human Behaviour - Biba et al. show that episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz.
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duncanlabuoft.bsky.social @duncanlabuoft.bsky.social · 06/03/2026
New paper out from the Duncan Lab in Nature Human Behaviour! Congratulations to lead author Thomas Biba @tbiba.bsky.social for all his hard work through the peaks and troughs, seeing this through to publication! Big thanks to our collaborators! @lexidecker.bsky.social @tvaliante.bsky.social
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Adrien Peyrache @apeyrache.bsky.social · 11/02/2026
New paper alert! 🚨 We found that the brain's compass is remarkably stable at two scales 1️⃣ the system maintains its internal organization for weeks 2️⃣ It "remembers" its orientation for weeks, even after a single visit This may be key to how the brain aligns its other maps. Paper: rdcu.be/e3waP
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Carsen Stringer @computingnature.bsky.social · 09/02/2026
🚨 new work from the lab on how eye movements 👀 versus orofacial movements influence 🐭 visual cortex activity 🧠 #neuroscience #behavior #neuroAI
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Paola A. Marignani @pmarignani.bsky.social · 03/02/2026
13% success rates at #CIHR, is a really 87% fail rate for>4000 scientists. At a time when 🇨🇦 is investing millions to recruit more scientist into a broken funding environment. 🇨🇦, U need a strong science foundation 2 attract success. #CIHR, fix your science foundation, it is eroding in real time
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Alexey Tolchinsky @tolchinsky.bsky.social · 02/02/2026
Intelligence and consciousness. @anilseth.bsky.social, brief, clear and to the point: "intelligence is about doing and consciousness is about being" www.noemamag.com/the-mytholog...
noemamag.com
The Mythology Of Conscious AI | NOEMA
Why consciousness is more likely a property of life than of computation and why creating conscious, or even conscious-seeming AI, is a bad idea.
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Guillaume Lajoie @glajoie.bsky.social · 15/01/2026
New eLife paper is out! We explore the link btw 2-phase perception/generation learning methods like wake-sleep, and what may happen in the brain under on psychedelics. Turns out hallucinations are consistent with hijacking phasic learning, essentially running both wake and sleep phases at once.
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Blake Richards @tyrellturing.bsky.social · 13/01/2026
Are you thinking about doing neuroscience outreach but want to make it more exciting or hands on? Check out RetINaBox! (A collab led by the Trenholm lab) We tried to bring the experience of experimental neuroscience to a classroom setting: www.eneuro.org/content/13/1... #neuroscience 🧪
eneuro.org
RetINaBox: A Hands-On Learning Tool for Experimental Neuroscience
An exciting aspect of neuroscience is developing and testing hypotheses via experimentation. However, due to logistical and financial hurdles, the experiment and discovery component of neuroscience is...
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Dirk Bernhardt-Walther @dirkbwalther.bsky.social · 09/01/2026
Wonderful article about our recent paper in @pnasnexus.org! Thanks, @sachapfeiffer.bsky.social and @mickbonner.bsky.social! @yikai-tang.bsky.social @uoftpsychology.bsky.social @artsci.utoronto.ca @utoronto.ca
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Andrew Pruszynski @andpru.bsky.social · 11/12/2025
My thoughts on the matter: www.nature.com/articles/s41...
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Anil Seth @anilseth.bsky.social · 10/12/2025
Wonderful and inspiring opening session at the CIFAR/TWCF Winter School for the Neuroscience of Consciousness, here in beautiful wintery Montebello, in Quebec. All of the participants gave 60 second intros to themselves and their interests. What a great group of people.
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Shahab Bakhtiari @shahabbakht.bsky.social · 08/12/2025
In this piece for @thetransmitter.bsky.social, I argue that ecological neuroscience should leverage generative video and interactive models to simulate the world from animals' perspectives. The technological building blocks are almost here - we just need to align them for this application. 🧠🤖
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allen institute @alleninstitute.org · 05/12/2025
🧠📢 New preprint alert Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵 #neuroskyence #compneurosky
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allen institute @alleninstitute.org · 05/12/2025
Lossy WavPack compression (up to 7× reduction) has minimal impact on sorting accuracy. This offers major storage savings without sacrificing quality.
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Dirk Bernhardt-Walther @dirkbwalther.bsky.social · 02/12/2025
Energy efficiency drives evolution, and humans may have evolved pleasure-based signals to optimize actions. Does this extend to aesthetic pleasure? Yes! Strong evidence in silico and humans, out in PNAS Nexus: tinyurl.com/3kbu8xw4 With Yikai Tang and Wil Cunningham. @uoftpsychology.bsky.social
Conceptual Roadmap of the present study. To examine the relationship between the metabolic costs of visual processing and aesthetic pleasure, we used both computational and physiological measures to quantify metabolic costs during visual processing: 1. Model-derived estimates of metabolic costs based on the activation of a deep neural network; 2. Metabolic activity of human brains, specifically in the visual processing areas. We found that both measures were inversely related to aesthetic pleasure.
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Richard Gao @rdgao.bsky.social · 03/12/2025
Finally got the job ad—looking for 2 PhD students to start spring next year: www.gao-unit.com/join-us/ If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply! I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮
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Timothy O'Leary @timothyoleary.bsky.social · 03/12/2025
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28! www.cam.ac.uk/jobs/univers...
cam.ac.uk
University Assistant/Associate Professor in Control Theory and Systems Biology
Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group
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Richard Gao @rdgao.bsky.social · 24/11/2025
hey I'm reposting this for no reason at all today... www.cell.com/trends/cogni...
cell.com
Processes and measurements: a framework for understanding neural oscillations in field potentials
Various neuroscientific theories maintain that brain oscillations are important for neuronal computation, but opposing views claim that these macroscale dynamics are ‘exhaust fumes’ of more relevant p...
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Nature Portfolio @natureportfolio.nature.com · 23/11/2025
A study in Nature Communications identifies BNST theta and prefrontal BNST coherence as intracranial biomarkers predicting depression outcomes after deep brain stimulation. Lower activity predicted better long-term benefit, linking brain circuits to emotional bias and anxiety. 🧪
go.nature.com
Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression - Nature Communications
This study identifies BNST theta and prefrontal BNST coherence as intracranial biomarkers predicting depression outcomes after DBS. Lower activity predicted better long-term benefit, linking brain circuits to emotional bias and anxiety.
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CRANIA @crania-toronto.bsky.social · 27/03/2025
It was incredible to be part of #purpleday yesterday! 💜 Each year, this important day continues to grow bigger and stronger, bringing more awareness and support for the 1-in-100 people living with epilepsy. @kbi-uhn.bsky.social @uhnresearch.bsky.social @tvaliante.bsky.social
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Maurizio De Pittà @mdepitta.bsky.social · 15/02/2025
Happy to share this work putting forth the first #computational model of #developing #embrionic cortical circuits. Phenomenal team coordination by Fernando Garcia Moreno @achucarro.bsky.social. @kbi-uhn.bsky.social @kcnhub.bsky.social
science.org
Evolutionary convergence of sensory circuits in the pallium of amniotes
The amniote pallium contains sensory circuits that are structurally and functionally equivalent, yet their evolutionary relationship remains unresolved. We used birthdating analysis, single-cell RNA a...
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Jason Haslam @jasonhaslam.ca · 07/02/2025
I’m not “abandoning my diet”; I’m “supporting my country.”
A 210 gram bag of Hawkins Cheesies, made with real Canadian cheddar.
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allen institute @alleninstitute.org · 01/01/2025
New brain aging study is out today in Nature The largest single-cell RNA seq dataset of mouse brain aging reveals incredible insights and could pave the way for future therapies to slow or manage the impacts of the aging process. 🧵 #studyBRAIN
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Paul Frankland @franklandlab.bsky.social · 27/12/2024
Just bumping this up for those who may have missed earlier announcements-- we have a new PI position in the Neuroscience & Mental Health program here at SickKids. Neural and glial mechanisms in cognition.
can-acn.org
Scientist/Senior Scientist – Research Institute, Hospital for Sick Children, University of Toronto – Canadian Association for Neuroscience
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CRANIA @crania-toronto.bsky.social · 24/12/2024
We are proud to support this trial through our our extensive academic and clinical programs affiliated with @uoft.bsky.social @uhnresearch.bsky.social bsky.app/profile/uhnt...
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allen institute @alleninstitute.org · 11/12/2024
Congrats to Sam Mestern, Ph.D. student at @westernu.bsky.social, for winning the MapMySpikes challenge! His tool, PatchOTDA, excelled in mapping electrophysiological data to molecular properties. 🧠📈 More on his tool and the MapMySpikes challenge: alleninstitute.org/news/canadia...
alleninstitute.org
Canadian Ph.D. student, Sam Mestern, wins first MapMySpikes challenge
The Allen Institute for Brain Science's MapMySpikes challenge aimed to address a key challenge in neuroscience by making connections between cells' electrical and molecular properties.
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Research at UHN @uhnresearch.ca · 10/12/2024
Three UHN research projects have received over $4M through the Ontario Research Fund, part of a $92M investment in Ontario research! Learn how this funding advances: ▶️#MRI tech ▶️#AI for donor lungs ▶️Muscle & joint #health Congrats to the awardees! 🔗 www.uhnresearch.ca/news/investi...
Collage of five smiling male researchers of diverse backgrounds with institutional logos at the bottom.
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Nima Dehghani @neurovium.bsky.social · 08/12/2024
Hopfield and Hinton @nobelprize.bsky.social lecture today John J. Hopfield: Physics is a point of view Geoffrey Hinton: Boltzmann Machines www.youtube.com/live/lPIVl5e...
youtube.com
YouTube
Share your videos with friends, family, and the world
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Taufik A. Valiante @tvaliante.bsky.social · 06/12/2024
Grateful for these two and that they find such joy in one another!! Photo cred @samravaliante.bsky.social
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Taufik A. Valiante @tvaliante.bsky.social · 03/12/2024
Holiday festivities have begun. Grateful for my amazing lab for making each year fun, and exciting!!
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Lars Kasper @mrikasper.bsky.social · 02/12/2024
Done Christmas Shopping? Or need inspiration what open MRI tools to get for your loved ones? After Black Friday and Cyber Monday, there is 🥁 #MRITogether Tuesday (and Wednesday-Thursday-Friday 😉). There is still time to register for our free online event mritogether.esmrmb.org/24m/registra...
mritogether.esmrmb.org
Registration and How to Attend
How to register
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Bo Wang @bowang87.bsky.social · 27/11/2024
Thank you to the global community for citing, sharing, and building on this work! 🙏 Read the paper here: nature.com/articles/s41... Stay tuned for MedSAM2, set to be released next month, offering enhanced efficiency and accuracy for medical video and 3D image segmentation.
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Bo Wang @bowang87.bsky.social · 20/11/2024
thanks @haoyin.bsky.social 🙏🙏
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Scott Rich, Ph.D. @richcompneuro.bsky.social · 26/11/2024
An early Thanksgiving gift to you all… a new preprint, representing the final piece of my postdoc work at @kbi-uhn.bsky.social @kcnhub.bsky.social @uhnresearch.bsky.social with @tvaliante.bsky.social. Full description to come next week 😀 #neuroskyence #compneuro www.biorxiv.org/content/10.1...
biorxiv.org
H- and m-channel overexpression promotes seizure-like events by impairing the ability of inhibitory neurons to process correlated inputs
Channelopathies affecting h- and m-channels present a paradox in epilepsy research: while both over- and underexpression of these channels can be epileptogenic, channel overexpression does not appear ...
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Nima Dehghani @neurovium.bsky.social · 25/11/2024
Oh I know this guy. I listen to him all the time. But more importantly, you should see what his colleagues have to say about "To Keep or Not to Keep"
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Jibran Khokhar @drjkhokhar.bsky.social · 25/11/2024
Also for those with broader brain health related interests where you get to play with these toys! If it sounds interesting, let’s chat at ACNP in Phoenix!
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Maurizio De Pittà @mdepitta.bsky.social · 24/11/2024
I am giving a 2-day #advanced #course on #astrocyte multiscale #models at the University of #Padua IT on April 10--11, 2025 #EMBO. An excellent opportunity to learn how to include #neuron-#glia #interactions in your models, from molecules to networks. Info & Registration: tinyurl.com/yx3m6acy
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Konrad Kording @kordinglab.bsky.social · 21/11/2024
The most fun paper I have ever written. Great theory, too. Read it if you want to understand the American Psyche.
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