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Maurizio De Pittà

@mdepitta.bsky.social
367 followers 503 following 15 posts

Quodlibetic twitter on #Neuroscience and related #Arts. Luscious #glia supporter, prone to irreverence, and curmudgeonly regarding religions | Neuron-Glial Interactions Group Leader at @KCNhub and @KBI_UHN | Assistant Professor at the University of Toronto

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Maurizio De Pittà @mdepitta.bsky.social · 21/04/2025
The first @embo.org #Astrocyte #Meeting was a success! Thanks to our excellent speakers, brilliant trainees, & DiBio @unipd.bsky.social volunteers. Looking forward to the next iteration! Laura.Civiero Matthew.Holt Olga.Sin WonSuk.Chun Keith.Murai Valentin.Nagerl @carmenfalcone.bsky.social
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Maurizio De Pittà @mdepitta.bsky.social · 19/04/2025
@embo.org Astrocyte has been a success. Our lab at @kcnhub.bsky.social contributed by three posters and one talk in a continuous endeavor to build a #biophysical #theory of the #brain that puts #tripartite neuron #astrocytes circuits at its core @kbi-uhn.bsky.social Thanks team & brilliant peers.
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Maurizio De Pittà @mdepitta.bsky.social · 17/04/2025
Great feedback from a galvanizing community at @embo.org #Astrocye Meeting where @zhenyangsun.bsky.social presented our data unravelling how #anatomy shapes astrocyte function @kcnhub.bsky.social @kbi-uhn.bsky.social
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Maurizio De Pittà @mdepitta.bsky.social · 15/02/2025
Happy to share this work putting forth the first #computational model of #developing #embrionic cortical circuits. Phenomenal team coordination by Fernando Garcia Moreno @achucarro.bsky.social. @kbi-uhn.bsky.social @kcnhub.bsky.social
science.org
Evolutionary convergence of sensory circuits in the pallium of amniotes
The amniote pallium contains sensory circuits that are structurally and functionally equivalent, yet their evolutionary relationship remains unresolved. We used birthdating analysis, single-cell RNA a...
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Reposted by Maurizio De Pittà
Eduardo Zimmer @erzimmer.bsky.social · 14/02/2025
Despite carrying a genetic mutation associated with early-onset #Alzheimer’s, a man remained free of dementia symptoms for at least 2 decades longer than expected 👉 genetic variants may explain this remarkable resilience. See more here: www.nature.com/articles/d41...
idp.nature.com
A man was destined for early Alzheimer’s — these genes might explain his escape
Scientists identify nine genetic variants that could have helped a man to avoid dementia for at least two decades longer than expected.
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Reposted by Maurizio De Pittà
Ulises Pereira-Obilinovic @ulisespereirao.bsky.social · 07/12/2024
I am excited to share the last work of my postdoc as a Swartz Fellow at NYU on the dynamic routing of large-scale cognitive networks in the neocortex! 🌐🧠 Here's a quick breakdown: 🧵 preprint: www.biorxiv.org/content/10.1...
biorxiv.org
Cognitive networks interactions through communication subspaces in large-scale models of the neocortex
The neocortex-wide neural activity is organized into distinct networks of areas engaged in different cognitive processes. To elucidate the underlying mechanism of flexible network reconfiguration, we ...
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Maurizio De Pittà @mdepitta.bsky.social · 28/11/2024
Claiming #LLM will outperform #humans in #neuroscience or #science discovery is #hallucination. LLMs may aid discovery, but producing #foundational #scientific discovery is #serendipitous, which #LLM will confuse with #noise. I see LLMs as more useful for #fact-checking a study tinyurl.com/bdsx2mxa
nature.com
Large language models surpass human experts in predicting neuroscience results - Nature Human Behaviour
Large language models (LLMs) can synthesize vast amounts of information. Luo et al. show that LLMs—especially BrainGPT, an LLM the authors tuned on the neuroscience literature—outperform experts in pr...
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Reposted by Maurizio De Pittà
Daniel Cardozo Pinto @dcardozopinto.bsky.social · 25/11/2024
My paper is out!! 🎉 "Opponent control of reinforcement by striatal dopamine and serotonin", @Nature Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain THREAD ⬇️ 1/n
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Maurizio De Pittà @mdepitta.bsky.social · 25/11/2024
Should we just raise the issue with the #Candian equivalent...?
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Maurizio De Pittà @mdepitta.bsky.social · 24/11/2024
I am giving a 2-day #advanced #course on #astrocyte multiscale #models at the University of #Padua IT on April 10--11, 2025 #EMBO. An excellent opportunity to learn how to include #neuron-#glia #interactions in your models, from molecules to networks. Info & Registration: tinyurl.com/yx3m6acy
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Reposted by Maurizio De Pittà
Eduardo Zimmer @erzimmer.bsky.social · 23/11/2024
‘A place of joy’: why scientists are joining the rush to 🦋 Just out in @natureportfolio.bsky.social 👇 www.nature.com/articles/d41...
nature.com
‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.
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Reposted by Maurizio De Pittà
Carmen Falcone @carmenfalcone.bsky.social · 19/11/2024
Sooo, there are still a few spots available if you want to give a talk at the third edition of #AstrocyteCafe 😏 #AstrocyteCafe is a FREE monthly seminars starting from January 2025! Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com!😍
Flyer saying: Call for speakers- Astrocyte Cafe 3rd edition/ Starting in January 2025 - online. Email: astrocytecafe@gmail.com
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Reposted by Maurizio De Pittà
Eduardo Zimmer @erzimmer.bsky.social · 20/11/2024
Paper of the year 2 👉 astrocytes, glucose, lactate, IDO1 and impressive results! 👇👇👇👇👇👇👇👇👇👇👇👇👇 www.science.org/doi/10.1126/...
science.org
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Impaired cerebral glucose metabolism is a pathologic feature of Alzheimer’s disease (AD), with recent proteomic studies highlighting disrupted glial metabolism in AD. We report that inhibition of indo...
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Reposted by Maurizio De Pittà
Steven Strogatz @stevenstrogatz.com · 20/11/2024
I'm just learning about Starter Packs. Here's a great place to find them! blueskydirectory.com
blueskydirectory.com
The Ultimate Directory of tools and applications for Bluesky
A curated collection of all things relating to the Blue Sky social media platform.
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