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Tom Hitch

@tcahitch.bsky.social
437 followers 207 following 51 posts

Assistant Professor at The Chinese University of Hong Kong focused on how we can control the human gut microbiota to improve human health. He/Him/They

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Reposted by Tom Hitch
Alex Crits-Christoph @acritschristoph.bsky.social · 06/09/2026
Transferable genetic toolsets for nonmodel gut Clostridia enable in vivo reversible control of metabolite production www.nature.com/articles/s41... A nice update to the Jin et al. 2022 paper from Chun-Jun Guo: now with many promoters for gut clostridiales, screened from native metatranscriptomes:
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Reposted by Tom Hitch
Nature Microbiology @natmicrobiol.nature.com · 26/08/2026
Out Now! A roadmap to create FAIR collections of microbial strains #MicroSky
go.nature.com
A roadmap to create FAIR collections of microbial strains
Nature Microbiology, Published online: 26 August 2026; doi:10.1038/s41564-026-02446-9Here the authors propose guidance on the process of establishing a state-of-the-art collection of microorganisms, including project planning, strain deposition and the naming of new taxa.
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Thomas Clavel @tclavel.bsky.social · 26/08/2026
Drawing on the team’s knowledge acquired over the years, we share our thoughts here on how to enhance microbiome research with FAIR collections of microbial strains: 🔥 www.nature.com/articles/s41... @nfdi4microbiota.bsky.social, @spp2474.bsky.social, @dsmz.bsky.social, @natmicrobiol.nature.com.
nature.com
A roadmap to create FAIR collections of microbial strains - Nature Microbiology
Here the authors propose guidance on the process of establishing a state-of-the-art collection of microorganisms, including project planning, strain deposition and the naming of new taxa.
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André Soares @geomicrosoares.bsky.social · 07/08/2026
Come work with us, we're really cool people to hang out with 😁 You'll get to do interdisciplinary research exploring microbial metabolisms during the Archean Eon by investigating the deep biosphere in high-CO₂ ecosystems hundreds of meters below ground. Please retweet and spread the word! 🧬 💻
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Reposted by Tom Hitch
Sean Gibbons 🦠💩 @gibbological.bsky.social · 23/07/2026
Dear microbiome enthusiasts: I'm excited to be moving my lab to New York University this fall (& the NYU Institute for Engineering Health); with joint-appointment @isbscience.org I'm hiring a postdoc @ NYU to look at diet-driven evolution in the gut: apply.interfolio.com/189980 Please share! 🦠🤓
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Tom Hitch @tcahitch.bsky.social · 16/07/2026
PhD advert for the new lab in Hong Kong! We are hiring a PhD student to merge large-scale metagenomics with 3D structural analysis and immunology. If you have experience in any of these areas and are motivated to learn the others, get in contact; lnkd.in/ggr3T4sQ
CUHK campus in Hong Kong
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Tom Hitch @tcahitch.bsky.social · 07/07/2026
PhD advert for the new lab in Hong Kong! We are hiring a PhD student to merge large-scale metagenomics with 3D structural analysis and immunology. If you have experience in any of these areas and are motivated to learn the others, get in contact; www.aic.cuhk.edu.hk/web/wp-conte...
The Chinese University of Hong Kong campus along side Sha Tin bay.
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Thomas Clavel @tclavel.bsky.social · 25/06/2026
Excellent work by our one and only #CharliePauvert. We use it in all our high-throughput anaerobic cultivation projects. More to come... 💫
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Tom Hitch @tcahitch.bsky.social · 19/06/2026
Great talk from Jianbo Zhang on the GuMI system at #INFOGUT2026 @infogut.bsky.social
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infogut.bsky.social @infogut.bsky.social · 18/06/2026
🚨 #INFOGUT2026 meeting has started! WG leaders welcome you ✨ Andrea Gianotti Stéphanie Blanquet Lorenzo Nissen Clarisse Nobre Lidia Tomas Lucie Etienne Thomas Hitch @tcahitch.bsky.social Enrique Carrillo Alice Ponsero Laure-Alix Clerbaux Pilar Acedo @pilaracedo.bsky.social
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infogut.bsky.social @infogut.bsky.social · 16/03/2026
🚨 INFOGUT FREE webinar 🗓️ 30 March @ 11.00 CET 🗣️ Prof Tom Van de Wiele (Ghent University) will share his cutting-edge expertise on #invitro technologies for mimicking the #human #microbiome in the small #intestine. 👉 Open to everyone on Teams lnkd.in/eHZ6X8iz
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Reposted by Tom Hitch
James McDonald @jamesemcdonald.bsky.social · 11/02/2026
Delighted to see our work on the impact of drought on the oak microbiome featured on the cover of @cp-cellhostmicrobe.bsky.social Link to the article below this post 👇🏻
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Tom Hitch @tcahitch.bsky.social · 03/02/2026
Anyone know where you can buy acrolein for electron microscopy? Apparently it must be stabilised with either hydrochinon or hydroquinon-monomethylether 🫠
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Reposted by Tom Hitch
Patrick R. Secor @prsecor.bsky.social · 28/01/2026
Friends, please help spread the word about our microbiology REU program at Montana State University. www.montana.edu/mbi/reu/ Each student receives a stipend ($7000 for 10 wks). Travel compensation, room, and board are also provided. Details in the attached pic--Feb 14 deadline 🧫🧪🦠#microsky
This Research Experiences for Undergraduates (REU) program is funded by the National Science Foundation to create "points of entry" for students interested in research. Students apply from across the country to spend 10 weeks in Bozeman, Montana this summer (May 26, 2026 - August 1, 2026). Admitted students are paired with a faculty mentor, who serves as an advisor for a student's summer project. Each student receives a stipend ($7000 for 10 wks). Travel compensation, room, and board are also provided.

Our program leverages MSU’s unique microbiology expertise, focusing specifically on microbes living with little or no oxygen (like those in the hot springs of nearby Yellowstone). Low oxygen microbes are essential to human and ecosystem health. They influence (or control) such processes as the breakdown of food in the GI tract, removal of toxins from our bodies and the environment, and production of greenhouse gases. They are also models for understanding the origins of life on this planet, and the potential for life on other planets.

A key goal of our program is to recruit students from schools with limited research infrastructure. Being in Montana, a state with a vibrant Native American community, we are particularly interested in applications from students at tribal colleges. However, ANYONE with an interest in microbiology - or biology/science in general - can and should apply.

If willing and able, please share/tweet/spread the word far and wide. Applications are due February 14, 2026. Full details can be found through our website http://www.montana.edu/mbi/reu/
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Pascal Falter-Braun @interactome.bsky.social · 26/01/2026
Very happy and proud that our paper “Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation” is out today in #NatureMicrobiology @natmicrobiol.nature.com Paper 👉 t1p.de/v42xb #microbiome #commensal #pathomechanism #T3SS #immune #health #IBD
t1p.de
Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation - Nature Microbiology
Large-scale computational and in vitro analyses identify commensal type III secretion systems and substrates in the human gut microbiome that can interact with human proteins to modulate immune pathwa...
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Chris Creevey @hairyllama.bsky.social · 23/01/2026
Last chance to apply for our funded PhD opportunity. w. Prof. Fredric Coulon @ Cranfield University. This will investigate expansion of ML models for AMR phenotype detection to agriculture settings to create a sensor-ready hit list. Detail here: www.findaphd.com/phds/project...
findaphd.com
From Genomic Context to Sensor Design: Computational Identification of AMR Biomarkers in Agriculture (project at Queen's University Belfast) at University of Reading on FindAPhD.com
PhD Project - From Genomic Context to Sensor Design: Computational Identification of AMR Biomarkers in Agriculture (project at Queen's University Belfast) at University of Reading, listed on FindAPhD....
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Reposted by Tom Hitch
Christoph Kaleta @kaletalab.bsky.social · 04/12/2025
(1/7) Excited that the Virtual Colon, an extension of BacArena for modeling the spatiostructural environment of the colon, is now out at mSystems. Kudos to @maringos.bsky.social and for leading this work! @crc1182.bsky.social @uni-kiel.de iel.de Link: journals.asm.org/doi/full/10....
journals.asm.org
Virtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment | mSystems
Interactions between the human body and gut microbes are crucial for health and disease. We present the Virtual Colon, an extension of the individual-based microbiome modeling approach BacArena that m...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 03/12/2025
Virtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment #mSystems from @kaletalab.bsky.social journals.asm.org/doi/10.1128/...
journals.asm.org
Virtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment | mSystems
Interactions between the human body and gut microbes are crucial for health and disease. We present the Virtual Colon, an extension of the individual-based microbiome modeling approach BacArena that m...
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Reposted by Tom Hitch
Alejandra Ordonez @alejandra1909.bsky.social · 19/11/2025
The pre print of my PhD research is out! 📣 Check it out for some cool results on high-throuhput microbial isolation, #SynComs and #Tree #Microbiome 🌳🧫 doi.org/10.1101/2025... #PhDone 💯
doi.org
Large-scale culturing of the tree microbiome enables targeted disease suppression
The tree microbiome is essential for host health and pathogen suppression. Synthetic microbial communities (SynComs) are emerging as important tools to understand microbiome dynamics and engineer micr...
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Reposted by Tom Hitch
Francis M. Martin @fmartin54.bsky.social · 14/11/2025
We are delighted to let you know that your Plants, People, Planet article 'Demystifying Fungal Systematics: A Gateway to Fungal Literacy and Societal/Ecological Relevance Through Familiar Species' has been published on Early View. nph.onlinelibrary.wiley.com/doi/10.1002/...
nph.onlinelibrary.wiley.com
Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidn...
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Tom Hitch @tcahitch.bsky.social · 14/11/2025
Want to delineate genera? We have been optimising POCP, and propose POCPu, which stops the 'double counting' of proteins in POCP by only allowing unique matches. We also speed up, and benchmarked, the analysis using DIAMOND; peerj.com/articles/202... (now implemented in Protologger)
peerj.com
Fast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu)
Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies...
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Reposted by Tom Hitch
Martin Fenk @mfenk.bsky.social · 27/10/2025
Is the human microbiome a source for hospital-associated infections (HAI) and are any genetic changes associated with HAI? In our new preprint, we longitudinally reconstruct the evolutionary processes within the human microbiome leading up to HAI: doi.org/10.1101/2025...
doi.org
Colonization, translocation, and evolution of opportunistic pathogens during hospital-associated infections
Many commensal bacteria that peacefully reside in the human microbiome are also able to cause acute opportunistic infections. Emerging evidence suggests that within-host evolution contributes to infec...
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starchlab.bsky.social @starchlab.bsky.social · 14/10/2025
Come and do a PhD with me! Are you looking for a PhD project at the intersection of #microbiome and #food science? This project, in collaboration with ADM milling, will explore novel microbiome targeted food ingredients
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Mizrahi Lab @mizrahilab.bsky.social · 28/09/2025
How to design new synthetic microbial communities? It's a huge question we're still deeply exploring 🦠 Check out this new preprint by @tcahitch.bsky.social & @tclavel.bsky.social! They developed an function-directed approach using metagenomic to build better SynComs. www.biorxiv.org/content/10.1...
biorxiv.org
Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies
Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynComs). We developed a functionally directed approach to ge...
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Alex Probst @alexjprobst.bsky.social · 26/09/2025
New article on equitable reuse of public sequencing data, published in @natmicrobiol.nature.com! Led by the Data reuse core team @lhug.bsky.social @environmicrobio.bsky.social Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and with Anke Heyer and The Data Reuse Consotrium!
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Tom Hitch @tcahitch.bsky.social · 24/09/2025
The main work from my time in Aachen is now out 🎉 if you have wanted to make a SynCom that captures the functional-landscape of microbiota, MiMiC2 makes that possible based on metagenomic data! 1/7 doi.org/10.1093/isme...
doi.org
Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies
Abstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom
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Benjamin Coltman @bcoltman.bsky.social · 23/09/2025
It’s also timely to present about SynCom design considering the recent work from @tcahitch.bsky.social @tclavel.bsky.social. I highly recommend reading! academic.oup.com/ismej/advanc...
academic.oup.com
Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies
Abstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom
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Christoph Kaleta @kaletalab.bsky.social · 22/09/2025
Excellent article on quantitative production of fermentation products by the microbiota. Key takeaway: microbial fermentation products may be more important in mice than humans, amplifying microbiome effects in mice. www.cell.com/cell/fulltex...
cell.com
Quantifying the varying harvest of fermentation products from the human gut microbiota
Fermentation products are the most abundant gut microbial metabolites absorbed by the host, with important dose-dependent consequences for health. In this study, we present a systems-level analysis in...
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Reposted by Tom Hitch
Rayan Chikhi @rayanchikhi.bsky.social · 03/09/2025
🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024...
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Hall Lab @halllab.bsky.social · 18/08/2025
Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com! We show that probiotics help modulate the preterm infant 👶#microbiome - to reduce ARGs, lower MDR bacteria 🦠 & increase beneficial Bifido ✨ Huge team effort! www.nature.com/articles/s41...
nature.com
Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants - Nature Communications
Here, the authors show that giving probiotics to very low birth weight preterm babies can help reduce harmful antibiotic-resistant bacteria in the gut and support the development of a healthier microb...
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Marine C. Cambon @marccamb.bsky.social · 16/08/2025
Go and check out the pre-print of the landscape-scale tree microbiome study from the Future Oak project. Huge amounts of efforts and talent went into this work, with a pinch of "this is crazy, but we can do it". Well done @jamesemcdonald.bsky.social @cenococcum.bsky.social et al. Thread below 👇
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James McDonald @jamesemcdonald.bsky.social · 16/08/2025
🧵 New preprint alert! From the Future Oak project, led by @cenococcum.bsky.social Landscape-scale impacts of environment and disease on the tree microbiome 🌳🦠 www.biorxiv.org/content/10.1...
biorxiv.org
Environment and disease have tissue-specific effects on the tree microbiome
Trees are essential for ecosystem function, but due to their long lifespan, are disproportionately impacted by climate change and disease. Tree-associated microbiota are critical for tree health and r...
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April Hayes @aprilhayes.bsky.social · 18/07/2025
well this is kinda cool 🦠✨
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Nature Microbiology @natmicrobiol.nature.com · 16/07/2025
New RESOURCE! Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria @arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co #microbiomesky #microsky www.nature.com/articles/s41...
nature.com
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria - Nature Microbiology
A comprehensive genomic analysis reveals species- and strain-level heterogeneity in carbohydrate utilization potential across bifidobacteria of human origin.
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Diamond Lab @diamondlab.bsky.social · 16/07/2025
Our friends @thehesslab.bsky.social are actively looking for postdoctoral researchers interested in anerobic microbiology, and studying the rumen microbiome. #microbiologists #bioinformatics #microbiomes Check out their website: hesslab.com
hesslab.com
Hess Laboratory – Systems Microbiology & Natural Products Research
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James Lloyd 🧬 @jamespblloyd.bsky.social · 13/07/2025
An update to my recent pre-print: Start right to end right: authentic open reading frame selection matters has just gone online. In it, we look at the effect of mis-annotating an ORF on a spliced gene's predicted protein structure. www.biorxiv.org/content/10.1...
Protein structures, mostly unstructured. Three of them. First is complete and the other two are truncations. The rightmost is a very small truncation.
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Umeå Plant Science Centre @umeaplantsciencecentre.se · 09/07/2025
🧪🌾 VACANCIES - Are you looking for a postdoc or group leader opportunity? Come and work with us at @umeaplantsciencecentre.se 🌱! 🍀 We have currently several job openings available. Take a look on our homepage and apply: www.upsc.se/jobs.html #PlantSciJobs #plantscience #hiring
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rosiemackay2025.bsky.social @rosiemackay2025.bsky.social · 03/07/2025
UK Gut-Immune-Brain Axis Network+ We are building a UK-wide interdisciplinary research community to advance the mechanistic understanding of the gut-immune-brain axis.  Join our network to find out about our UK-wide launch event, where we will announce #funding opportunities www.giba-uk.org
giba-uk.org
Home | Giba Network UK | Gut Immune Brain Axis Network
Gut Immune Brain Axis Network (GIBA Network)
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Paula Ramiro-Martínez @paularamiro.bsky.social · 02/07/2025
Curious about plasmid biology? Our latest paper is out now in Nature Communications! 🚨 doi.org/10.1038/s414... We analyzed thousands of diverse bacterial plasmids to shed light for the first time on a key aspect of plasmid biology: plasmid copy number. 1/7 👇
doi.org
Universal rules govern plasmid copy number - Nature Communications
Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...
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Matti Ruuskanen @begia.bsky.social · 02/07/2025
www.nature.com/articles/s41... Our new paper on the risks and socio-demographic dimensions of antibiotic resistance in the human gut is now out in @natcomms.nature.com!
nature.com
Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort - Nature Communications
Here, in a representative cohort of 7,095 Finnish adults, the authors reveal that gut antibiotic resistance is shaped not only by antibiotic use but also by the microbiome, diet, lifestyle, household ...
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Marine C. Cambon @marccamb.bsky.social · 01/07/2025
Go and check out the great review by @xinmingxu.bsky.social and collaborators in this issue, and also shout-out to @evolvedbiofilm.bsky.social for supporting amazing science art actually made by a real humans and not AI!
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Sara Mitri @saramitri.bsky.social · 01/07/2025
Beautiful new review paper in preprint bridging microbial ecology and classic ecology led by Maggie Vogel, @olimeacock.bsky.social and @annasophieweiss.bsky.social, also by @juliensluneau.bsky.social and @lambdapp.bsky.social from our lab (not me :)) ecoevorxiv.org/repository/v...
ecoevorxiv.org
Bridging the scales: what can microbial ecologists learn from classic ecology?
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Sebastian Schmidt @tsbschm.bsky.social · 27/06/2025
The team's first preprint is out! Led by ‪ ‪@vishnuprasoodanan.bsky.social‬‬ & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data? A 🧵.
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estergaya.bsky.social @estergaya.bsky.social · 25/06/2025
🚨 Job Alert at RBG Kew! We are looking for Lab Research Assistants in genomics to join our Fungarium Sequencing Project! Do you like Fungi? Do you want to develop new -omics techniques? Interested in historical collections? Join the team! Posts to start ASAP. Apply here:https://lnkd.in/e2BpWJpA
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Lisa Maier Lab | Tübingen @lisamaierlab.bsky.social · 17/06/2025
Ever wondered why proton pump inhibitors raise the risk of C. diff infections? Is it due to pH shifts or direct antibacterial effects on the gut microbiome? We think it’s the pH. 🧪💡 Dive into Julia & Patrick’s new paper for the full story! 📖👇 #Microbiome #PPI doi.org/10.1080/1949...
doi.org
Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model
Clostridioides difficile infections often occur after antibiotic use, but they have also been linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism – whether infection risk is due...
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 29/11/2023
Want to do a #PhD focusing on discovery, cultivation and characterization of novel prokaryotes? Come and join my group in the Laboratory of Microbiology at Wageningen University! Apply here: wur.nl/en/vacancy/p... #cultivation #microscopy #archaea #PhDposition Please share & repost
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Segata Lab @cibiocm.bsky.social · 04/06/2025
Let us introduce a new subspecies: ✨Catenibacterium mitsuokai subsp. tridentinum✨ Plus, we also propose a taxonomic reclassification of publicly available reference genomes belonging to the C. mitsuokai sp. More details ⬇️ www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Description of Catenibacterium mitsuokai subsp. tridentinum subsp. nov., an anaerobic bacterium isolated from human faeces, and emended description of C. mitsuokai
A recent metagenomic survey has revealed an unknown bacterial clade within the Catenibacterium mitsuokai species to be significantly more prevalent in non-urbanized populations, compared to urbanized ...
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Tom Hitch @tcahitch.bsky.social · 26/05/2025
If you study in vitro models of gut consider joining INFOGUT and attend our future meetings!
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