Reposted by Tom HitchAlex Crits-Christoph @acritschristoph.bsky.social · 06/09/2026 Transferable genetic toolsets for nonmodel gut Clostridia enable in vivo reversible control of metabolite production www.nature.com/articles/s41... A nice update to the Jin et al. 2022 paper from Chun-Jun Guo: now with many promoters for gut clostridiales, screened from native metatranscriptomes: 0115
Reposted by Tom HitchNature Microbiology @natmicrobiol.nature.com · 26/08/2026Out Now! A roadmap to create FAIR collections of microbial strains #MicroSkygo.nature.comA roadmap to create FAIR collections of microbial strainsNature Microbiology, Published online: 26 August 2026; doi:10.1038/s41564-026-02446-9Here the authors propose guidance on the process of establishing a state-of-the-art collection of microorganisms, including project planning, strain deposition and the naming of new taxa. 073
Reposted by Tom HitchThomas Clavel @tclavel.bsky.social · 26/08/2026Drawing on the team’s knowledge acquired over the years, we share our thoughts here on how to enhance microbiome research with FAIR collections of microbial strains: 🔥 www.nature.com/articles/s41... @nfdi4microbiota.bsky.social, @spp2474.bsky.social, @dsmz.bsky.social, @natmicrobiol.nature.com.nature.comA roadmap to create FAIR collections of microbial strains - Nature MicrobiologyHere the authors propose guidance on the process of establishing a state-of-the-art collection of microorganisms, including project planning, strain deposition and the naming of new taxa. 21310
Reposted by Tom HitchAndré Soares @geomicrosoares.bsky.social · 07/08/2026Come work with us, we're really cool people to hang out with 😁 You'll get to do interdisciplinary research exploring microbial metabolisms during the Archean Eon by investigating the deep biosphere in high-CO₂ ecosystems hundreds of meters below ground. Please retweet and spread the word! 🧬 💻 033
Reposted by Tom HitchSean Gibbons 🦠💩 @gibbological.bsky.social · 23/07/2026Dear microbiome enthusiasts: I'm excited to be moving my lab to New York University this fall (& the NYU Institute for Engineering Health); with joint-appointment @isbscience.org I'm hiring a postdoc @ NYU to look at diet-driven evolution in the gut: apply.interfolio.com/189980 Please share! 🦠🤓apply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 410076
Tom Hitch @tcahitch.bsky.social · 16/07/2026PhD advert for the new lab in Hong Kong! We are hiring a PhD student to merge large-scale metagenomics with 3D structural analysis and immunology. If you have experience in any of these areas and are motivated to learn the others, get in contact; lnkd.in/ggr3T4sQ 045
Tom Hitch @tcahitch.bsky.social · 07/07/2026PhD advert for the new lab in Hong Kong! We are hiring a PhD student to merge large-scale metagenomics with 3D structural analysis and immunology. If you have experience in any of these areas and are motivated to learn the others, get in contact; www.aic.cuhk.edu.hk/web/wp-conte... 021
Reposted by Tom HitchThomas Clavel @tclavel.bsky.social · 25/06/2026Excellent work by our one and only #CharliePauvert. We use it in all our high-throughput anaerobic cultivation projects. More to come... 💫 053
Tom Hitch @tcahitch.bsky.social · 19/06/2026Great talk from Jianbo Zhang on the GuMI system at #INFOGUT2026 @infogut.bsky.social 020
Reposted by Tom Hitchinfogut.bsky.social @infogut.bsky.social · 18/06/2026🚨 #INFOGUT2026 meeting has started! WG leaders welcome you ✨ Andrea Gianotti Stéphanie Blanquet Lorenzo Nissen Clarisse Nobre Lidia Tomas Lucie Etienne Thomas Hitch @tcahitch.bsky.social Enrique Carrillo Alice Ponsero Laure-Alix Clerbaux Pilar Acedo @pilaracedo.bsky.social 031
Reposted by Tom Hitchinfogut.bsky.social @infogut.bsky.social · 16/03/2026🚨 INFOGUT FREE webinar 🗓️ 30 March @ 11.00 CET 🗣️ Prof Tom Van de Wiele (Ghent University) will share his cutting-edge expertise on #invitro technologies for mimicking the #human #microbiome in the small #intestine. 👉 Open to everyone on Teams lnkd.in/eHZ6X8izlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 022
Reposted by Tom HitchJames McDonald @jamesemcdonald.bsky.social · 11/02/2026Delighted to see our work on the impact of drought on the oak microbiome featured on the cover of @cp-cellhostmicrobe.bsky.social Link to the article below this post 👇🏻 43110
Tom Hitch @tcahitch.bsky.social · 03/02/2026Anyone know where you can buy acrolein for electron microscopy? Apparently it must be stabilised with either hydrochinon or hydroquinon-monomethylether 🫠 000
Reposted by Tom HitchPatrick R. Secor @prsecor.bsky.social · 28/01/2026Friends, please help spread the word about our microbiology REU program at Montana State University. www.montana.edu/mbi/reu/ Each student receives a stipend ($7000 for 10 wks). Travel compensation, room, and board are also provided. Details in the attached pic--Feb 14 deadline 🧫🧪🦠#microsky 36182
Reposted by Tom HitchPascal Falter-Braun @interactome.bsky.social · 26/01/2026Very happy and proud that our paper “Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation” is out today in #NatureMicrobiology @natmicrobiol.nature.com Paper 👉 t1p.de/v42xb #microbiome #commensal #pathomechanism #T3SS #immune #health #IBDt1p.deEffector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation - Nature MicrobiologyLarge-scale computational and in vitro analyses identify commensal type III secretion systems and substrates in the human gut microbiome that can interact with human proteins to modulate immune pathwa... 12511
Reposted by Tom HitchChris Creevey @hairyllama.bsky.social · 23/01/2026Last chance to apply for our funded PhD opportunity. w. Prof. Fredric Coulon @ Cranfield University. This will investigate expansion of ML models for AMR phenotype detection to agriculture settings to create a sensor-ready hit list. Detail here: www.findaphd.com/phds/project...findaphd.comFrom Genomic Context to Sensor Design: Computational Identification of AMR Biomarkers in Agriculture (project at Queen's University Belfast) at University of Reading on FindAPhD.comPhD Project - From Genomic Context to Sensor Design: Computational Identification of AMR Biomarkers in Agriculture (project at Queen's University Belfast) at University of Reading, listed on FindAPhD.... 056
Reposted by Tom HitchChristoph Kaleta @kaletalab.bsky.social · 04/12/2025(1/7) Excited that the Virtual Colon, an extension of BacArena for modeling the spatiostructural environment of the colon, is now out at mSystems. Kudos to @maringos.bsky.social and for leading this work! @crc1182.bsky.social @uni-kiel.de iel.de Link: journals.asm.org/doi/full/10....journals.asm.orgVirtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment | mSystemsInteractions between the human body and gut microbes are crucial for health and disease. We present the Virtual Colon, an extension of the individual-based microbiome modeling approach BacArena that m... 1115
Reposted by Tom HitchÁkos T Kovács @evolvedbiofilm.bsky.social · 03/12/2025Virtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment #mSystems from @kaletalab.bsky.social journals.asm.org/doi/10.1128/...journals.asm.orgVirtual Colon: spatiotemporal modeling of metabolic interactions in a computational colonic environment | mSystemsInteractions between the human body and gut microbes are crucial for health and disease. We present the Virtual Colon, an extension of the individual-based microbiome modeling approach BacArena that m... 022
Reposted by Tom HitchAlejandra Ordonez @alejandra1909.bsky.social · 19/11/2025The pre print of my PhD research is out! 📣 Check it out for some cool results on high-throuhput microbial isolation, #SynComs and #Tree #Microbiome 🌳🧫 doi.org/10.1101/2025... #PhDone 💯doi.orgLarge-scale culturing of the tree microbiome enables targeted disease suppressionThe tree microbiome is essential for host health and pathogen suppression. Synthetic microbial communities (SynComs) are emerging as important tools to understand microbiome dynamics and engineer micr... 0106
Reposted by Tom HitchFrancis M. Martin @fmartin54.bsky.social · 14/11/2025We are delighted to let you know that your Plants, People, Planet article 'Demystifying Fungal Systematics: A Gateway to Fungal Literacy and Societal/Ecological Relevance Through Familiar Species' has been published on Early View. nph.onlinelibrary.wiley.com/doi/10.1002/...nph.onlinelibrary.wiley.comDemystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar speciesFungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidn... 03222
Tom Hitch @tcahitch.bsky.social · 14/11/2025Want to delineate genera? We have been optimising POCP, and propose POCPu, which stops the 'double counting' of proteins in POCP by only allowing unique matches. We also speed up, and benchmarked, the analysis using DIAMOND; peerj.com/articles/202... (now implemented in Protologger)peerj.comFast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu)Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies... 022
Reposted by Tom HitchMartin Fenk @mfenk.bsky.social · 27/10/2025Is the human microbiome a source for hospital-associated infections (HAI) and are any genetic changes associated with HAI? In our new preprint, we longitudinally reconstruct the evolutionary processes within the human microbiome leading up to HAI: doi.org/10.1101/2025...doi.orgColonization, translocation, and evolution of opportunistic pathogens during hospital-associated infectionsMany commensal bacteria that peacefully reside in the human microbiome are also able to cause acute opportunistic infections. Emerging evidence suggests that within-host evolution contributes to infec... 12014
Reposted by Tom Hitchstarchlab.bsky.social @starchlab.bsky.social · 14/10/2025Come and do a PhD with me! Are you looking for a PhD project at the intersection of #microbiome and #food science? This project, in collaboration with ADM milling, will explore novel microbiome targeted food ingredients 024
Reposted by Tom HitchMizrahi Lab @mizrahilab.bsky.social · 28/09/2025How to design new synthetic microbial communities? It's a huge question we're still deeply exploring 🦠 Check out this new preprint by @tcahitch.bsky.social & @tclavel.bsky.social! They developed an function-directed approach using metagenomic to build better SynComs. www.biorxiv.org/content/10.1...biorxiv.orgFunction-Based Selection of Synthetic Communities Enables Mechanistic Microbiome StudiesUnderstanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynComs). We developed a functionally directed approach to ge... 1176
Reposted by Tom HitchAlex Probst @alexjprobst.bsky.social · 26/09/2025New article on equitable reuse of public sequencing data, published in @natmicrobiol.nature.com! Led by the Data reuse core team @lhug.bsky.social @environmicrobio.bsky.social Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and with Anke Heyer and The Data Reuse Consotrium! 03621
Tom Hitch @tcahitch.bsky.social · 24/09/2025The main work from my time in Aachen is now out 🎉 if you have wanted to make a SynCom that captures the functional-landscape of microbiota, MiMiC2 makes that possible based on metagenomic data! 1/7 doi.org/10.1093/isme...doi.orgFunction-Based Selection of Synthetic Communities Enables Mechanistic Microbiome StudiesAbstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom 11611
Reposted by Tom HitchBenjamin Coltman @bcoltman.bsky.social · 23/09/2025It’s also timely to present about SynCom design considering the recent work from @tcahitch.bsky.social @tclavel.bsky.social. I highly recommend reading! academic.oup.com/ismej/advanc...academic.oup.comFunction-Based Selection of Synthetic Communities Enables Mechanistic Microbiome StudiesAbstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom 252
Reposted by Tom HitchChristoph Kaleta @kaletalab.bsky.social · 22/09/2025Excellent article on quantitative production of fermentation products by the microbiota. Key takeaway: microbial fermentation products may be more important in mice than humans, amplifying microbiome effects in mice. www.cell.com/cell/fulltex...cell.comQuantifying the varying harvest of fermentation products from the human gut microbiotaFermentation products are the most abundant gut microbial metabolites absorbed by the host, with important dose-dependent consequences for health. In this study, we present a systems-level analysis in... 053
Reposted by Tom HitchRayan Chikhi @rayanchikhi.bsky.social · 03/09/2025🌎👩🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024... 3218118
Reposted by Tom HitchHall Lab @halllab.bsky.social · 18/08/2025Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com! We show that probiotics help modulate the preterm infant 👶#microbiome - to reduce ARGs, lower MDR bacteria 🦠 & increase beneficial Bifido ✨ Huge team effort! www.nature.com/articles/s41...nature.comImpact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants - Nature CommunicationsHere, the authors show that giving probiotics to very low birth weight preterm babies can help reduce harmful antibiotic-resistant bacteria in the gut and support the development of a healthier microb... 05426
Reposted by Tom HitchMarine C. Cambon @marccamb.bsky.social · 16/08/2025Go and check out the pre-print of the landscape-scale tree microbiome study from the Future Oak project. Huge amounts of efforts and talent went into this work, with a pinch of "this is crazy, but we can do it". Well done @jamesemcdonald.bsky.social @cenococcum.bsky.social et al. Thread below 👇 085
Reposted by Tom HitchJames McDonald @jamesemcdonald.bsky.social · 16/08/2025🧵 New preprint alert! From the Future Oak project, led by @cenococcum.bsky.social Landscape-scale impacts of environment and disease on the tree microbiome 🌳🦠 www.biorxiv.org/content/10.1...biorxiv.orgEnvironment and disease have tissue-specific effects on the tree microbiomeTrees are essential for ecosystem function, but due to their long lifespan, are disproportionately impacted by climate change and disease. Tree-associated microbiota are critical for tree health and r... 23817
Reposted by Tom HitchNature Microbiology @natmicrobiol.nature.com · 16/07/2025New RESOURCE! Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria @arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co #microbiomesky #microsky www.nature.com/articles/s41...nature.comIntegrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria - Nature MicrobiologyA comprehensive genomic analysis reveals species- and strain-level heterogeneity in carbohydrate utilization potential across bifidobacteria of human origin. 03922
Reposted by Tom HitchDiamond Lab @diamondlab.bsky.social · 16/07/2025Our friends @thehesslab.bsky.social are actively looking for postdoctoral researchers interested in anerobic microbiology, and studying the rumen microbiome. #microbiologists #bioinformatics #microbiomes Check out their website: hesslab.comhesslab.comHess Laboratory – Systems Microbiology & Natural Products Research 032
Reposted by Tom HitchJames Lloyd 🧬 @jamespblloyd.bsky.social · 13/07/2025An update to my recent pre-print: Start right to end right: authentic open reading frame selection matters has just gone online. In it, we look at the effect of mis-annotating an ORF on a spliced gene's predicted protein structure. www.biorxiv.org/content/10.1... 162
Reposted by Tom HitchUmeå Plant Science Centre @umeaplantsciencecentre.se · 09/07/2025🧪🌾 VACANCIES - Are you looking for a postdoc or group leader opportunity? Come and work with us at @umeaplantsciencecentre.se 🌱! 🍀 We have currently several job openings available. Take a look on our homepage and apply: www.upsc.se/jobs.html #PlantSciJobs #plantscience #hiring 0105
Reposted by Tom Hitchrosiemackay2025.bsky.social @rosiemackay2025.bsky.social · 03/07/2025UK Gut-Immune-Brain Axis Network+ We are building a UK-wide interdisciplinary research community to advance the mechanistic understanding of the gut-immune-brain axis. Join our network to find out about our UK-wide launch event, where we will announce #funding opportunities www.giba-uk.orggiba-uk.orgHome | Giba Network UK | Gut Immune Brain Axis NetworkGut Immune Brain Axis Network (GIBA Network) 074
Reposted by Tom HitchPaula Ramiro-Martínez @paularamiro.bsky.social · 02/07/2025Curious about plasmid biology? Our latest paper is out now in Nature Communications! 🚨 doi.org/10.1038/s414... We analyzed thousands of diverse bacterial plasmids to shed light for the first time on a key aspect of plasmid biology: plasmid copy number. 1/7 👇doi.orgUniversal rules govern plasmid copy number - Nature CommunicationsPlasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b... 411754
Reposted by Tom HitchMatti Ruuskanen @begia.bsky.social · 02/07/2025www.nature.com/articles/s41... Our new paper on the risks and socio-demographic dimensions of antibiotic resistance in the human gut is now out in @natcomms.nature.com!nature.comVariation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort - Nature CommunicationsHere, in a representative cohort of 7,095 Finnish adults, the authors reveal that gut antibiotic resistance is shaped not only by antibiotic use but also by the microbiome, diet, lifestyle, household ... 0106
Reposted by Tom HitchMarine C. Cambon @marccamb.bsky.social · 01/07/2025Go and check out the great review by @xinmingxu.bsky.social and collaborators in this issue, and also shout-out to @evolvedbiofilm.bsky.social for supporting amazing science art actually made by a real humans and not AI! 2104
Reposted by Tom HitchSara Mitri @saramitri.bsky.social · 01/07/2025Beautiful new review paper in preprint bridging microbial ecology and classic ecology led by Maggie Vogel, @olimeacock.bsky.social and @annasophieweiss.bsky.social, also by @juliensluneau.bsky.social and @lambdapp.bsky.social from our lab (not me :)) ecoevorxiv.org/repository/v...ecoevorxiv.orgBridging the scales: what can microbial ecologists learn from classic ecology? 14026
Reposted by Tom HitchSebastian Schmidt @tsbschm.bsky.social · 27/06/2025The team's first preprint is out! Led by @vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data? A 🧵. 14630
Reposted by Tom Hitchestergaya.bsky.social @estergaya.bsky.social · 25/06/2025🚨 Job Alert at RBG Kew! We are looking for Lab Research Assistants in genomics to join our Fungarium Sequencing Project! Do you like Fungi? Do you want to develop new -omics techniques? Interested in historical collections? Join the team! Posts to start ASAP. Apply here:https://lnkd.in/e2BpWJpA 125
Reposted by Tom HitchLisa Maier Lab | Tübingen @lisamaierlab.bsky.social · 17/06/2025Ever wondered why proton pump inhibitors raise the risk of C. diff infections? Is it due to pH shifts or direct antibacterial effects on the gut microbiome? We think it’s the pH. 🧪💡 Dive into Julia & Patrick’s new paper for the full story! 📖👇 #Microbiome #PPI doi.org/10.1080/1949...doi.orgProton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor modelClostridioides difficile infections often occur after antibiotic use, but they have also been linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism – whether infection risk is due... 01912
Reposted by Tom HitchThijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 29/11/2023Want to do a #PhD focusing on discovery, cultivation and characterization of novel prokaryotes? Come and join my group in the Laboratory of Microbiology at Wageningen University! Apply here: wur.nl/en/vacancy/p... #cultivation #microscopy #archaea #PhDposition Please share & repost 25253
Reposted by Tom HitchSegata Lab @cibiocm.bsky.social · 04/06/2025Let us introduce a new subspecies: ✨Catenibacterium mitsuokai subsp. tridentinum✨ Plus, we also propose a taxonomic reclassification of publicly available reference genomes belonging to the C. mitsuokai sp. More details ⬇️ www.microbiologyresearch.org/content/jour...microbiologyresearch.orgDescription of Catenibacterium mitsuokai subsp. tridentinum subsp. nov., an anaerobic bacterium isolated from human faeces, and emended description of C. mitsuokaiA recent metagenomic survey has revealed an unknown bacterial clade within the Catenibacterium mitsuokai species to be significantly more prevalent in non-urbanized populations, compared to urbanized ... 084
Tom Hitch @tcahitch.bsky.social · 26/05/2025If you study in vitro models of gut consider joining INFOGUT and attend our future meetings! 000