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Diamond Lab

@diamondlab.bsky.social
132 followers 33 following 18 posts

The Diamond Lab | Innovative Genomics Institute @ UC Berkeley | Metagenomics | Microbiome Systems Ecology and Modeling | AI for Microbes | Environmental MGEs | Health and Climate Change www.diamondlab.bio @innovativegenomics.bsky.social‬

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Cress Lab @cresslab.bsky.social · 30/04/2026
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
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Reposted by Diamond Lab
Alex Crits-Christoph @acritschristoph.bsky.social · 16/02/2026
Really crazy that these massive genes are 6% of the 1.5 Mbp genome in this bee gut symbiont:
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Reposted by Diamond Lab
Tae Seok Moon @taeseokmoon.bsky.social · 31/01/2026
#SynBYSS conference is scheduled on Jun 8-11, 2026 in Barcelona. Given the 100-year celebration of Architect Gaudi in Barcelona, we suggest early booking of hotels. Details can be found: www.jcvi.org/events/synbyss (speakers, abstract submission & registration) @jcvi.org @marcguellc.bsky.social
jcvi.org
SynBYSS
The International SynBYSS Conference is focused on bringing together the synthetic biology community with the explicit goal of developing young...
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Diamond Lab @diamondlab.bsky.social · 20/01/2026
We are extremely excited to share our newly designed lab website with our friends and scientific community: www.diamondlab.bio Design/coding performed by @gabo-bellamy.bsky.social with help from @leymiloslavich.bsky.social for infrastructure support. Huge thanks for bringing to fruition!!!
diamondlab.bio
Diamond Lab
Here a description
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Diamond Lab @diamondlab.bsky.social · 05/01/2026
🚨 Our Lab is HIRING! If you are interested in characterizing model microbiomes using genome-resolved methods, statistical/metabolic modeling, and/or machine learning please submit an application here: aprecruit.berkeley.edu/JPF05234 #postdoc #sciencejobs #biology #microbiome
aprecruit.berkeley.edu
Postdoc - Microbiome - Innovative Genomics Institute
University of California, Berkeley is hiring. Apply now!
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Reposted by Diamond Lab
Sarah J Tucker @sjtucker.bsky.social · 20/10/2025
I'm delighted our paper is out: doi.org/10.1093/isme... With new SAR11 isolate genomes and time-series metagenomes, we reveal coastal and offshore SAR11 ecotypes, identify associated metabolic traits, and pinpoint selective gene sweeps as a likely evolutionary driver to niche partitioning. 🌊🦠
doi.org
Habitat-specificity in SAR11 is associated with a few genes under high selection
Abstract. The order Pelagibacterales (SAR11) is the most abundant group of heterotrophic bacteria in the global surface ocean, where individual sublineages
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 17/11/2025
Read more here: innovativegenomics.org/news/a-micro...
innovativegenomics.org
A Microbial Blueprint for Climate-Smart Cows
A Microbial Blueprint for Climate-Smart Cows - Innovative Genomics Institute (IGI)
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Reposted by Diamond Lab
Amy Quinton @amymquinton.bsky.social · 18/11/2025
What if we could reprogram a cow's gut so it burps way less methane?🐮👏 @ucdavis.bsky.social & @innovativegenomics.bsky.social scientists found which microbes might help reduce methane w/o harming the cow. Boost that microbe & cows could become naturally cleaner for the climate! bit.ly/4oGv5YE 🧪
Three black-and-white and brown-and-white dairy cows munch on feed in a trough. Scientists may have found which microbes in a cow's gut could be used to cut methane emissions without harming the cow.
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Reposted by Diamond Lab
The Hess Lab @ UC Davis @thehesslab.bsky.social · 19/11/2025
Proud to finally have this work published and freely available for everyone: microbiomejournal.biomedcentral.com/articles/10....
microbiomejournal.biomedcentral.com
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Diamond Lab @diamondlab.bsky.social · 19/11/2025
We are thrilled to announce our latest publication in the Microbiome journal in collaboration with @thehesslab.bsky.social Supplementation with red seaweed in cows reduces methane and induces previously uncharacterized hydrogenotropic bacteria. microbiomejournal.biomedcentral.com/articles/10....
microbiomejournal.biomedcentral.com
Red seaweed supplementation suppresses methanogenesis in the rumen, revealing potentially advantageous traits among hydrogenotrophic bacteria - Microbiome
Background Macroalgae belonging to the genus Asparagopsis have shown to reduce methane (CH4) production during rumen fermentation, while increasing feed efficiency when added to the feed of cattle. Ho...
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 08/09/2025
📣🦠 New preprint: @savagecatsonly.bsky.social has got you covered with a new approach to building bacterial deletion libraries with unprecedented speed and ease: ow.ly/ltja50WSjBu
illustration of a petri dishes
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Reposted by Diamond Lab
The Washington Post @washingtonpost.com · 03/09/2025
Telehealth companies increasingly are marketing “microdoses” of GLP-1 drugs — despite how there is virtually no evidence that smaller-than-standard doses are safe or effective.
washingtonpost.com
How microdosing GLP-1 drugs became a longevity ‘craze’
Internet companies are helping stoke enthusiasm for “microdosing” weight-loss drugs for wellness, mood and joint pain.
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 03/09/2025
Self-cloning crops could transform agriculture – thanks to research from IGI's Venkatesan Sundaresan, who was awarded the 2024 Wolf Prize for his research on apomixis. Read more in this feature from @nature.com: ow.ly/Q7v350WQyne
illustrations of scientists manipulating DNA in a seed in a steam punk style
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Diamond Lab @diamondlab.bsky.social · 02/09/2025
Our paper on model cyanobacterial communities by @andrejakust.bsky.social is finally typeset and looks beautiful, check it out: academic.oup.com/ismej/articl...
academic.oup.com
Model cyanobacterial consortia reveal a consistent core microbiome independent of inoculation source or cyanobacterial host species
Abstract. Cyanobacteria are integral to biogeochemical cycles, influence climate processes, and hold promise for commercial applications. In natural habita
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 14/08/2025
Out now – our reader-friendly 2025 overview of #CRISPR clinical trials! Learn about how CRISPR is being used to treat #HeartDisease, #cancer, #lupus, #RareDiseases, and more! Read here: ow.ly/mRPl50WneTS 🧬
decorative illustration
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 18/08/2025
Congrats to IGI's @pcronald.bsky.social on receiving the President’s Award for the Advancement of the Common Good from Stanford University! 🎉 Read more: news.stanford.edu/stories/2025...
Pam Ronald smiling
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Reposted by Diamond Lab
UC Berkeley @ucberkeleyofficial.bsky.social · 14/08/2025
UC Berkeley researchers tweaked a key enzyme involved in microbial methane production to understand the different environments on Earth that generate the greenhouse gas. news.berkeley.edu/2025/08/14/s...
news.berkeley.edu
Scientists hack microbes to identify environmental sources of methane - Berkeley News
UC Berkeley researchers tweaked a key enzyme involved in microbial methane production to understand the unique fingerprints of different environments on Earth that generate the greenhouse gas.
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 11/08/2025
Did you know that the illustrations in our resources like CRISPRpedia and our illustrated scientific glossary are free to use for non-commercial, educational purposes? Tag us to show us how you're using them! innovativegenomics.org/science-x-art/
illustration of phage infecting and lysing a bacterium
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Diamond Lab @diamondlab.bsky.social · 01/08/2025
‼️Diamond Lab is considering potential a new postdoctoral researcher. If you have strong interests in microbiomes, metagenomics, machine learning, or rumen biology drop us a line and shoot us a CV!
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Diamond Lab @diamondlab.bsky.social · 01/08/2025
Love these!!! Now let’s see some communities in watercolor
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Diamond Lab @diamondlab.bsky.social · 01/08/2025
Think about all the amazing chemotropic microbes that must support this system!!! I hope they took samples
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 24/07/2025
Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨
innovativegenomics.org
Science x Art
Science x Art - Innovative Genomics Institute (IGI)
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Diamond Lab @diamondlab.bsky.social · 25/07/2025
Rally nice review on plasmid leading strand anti defense and establishment @bursteinlab.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Strategies for zygotic gene expression during plasmid establishment
Conjugative plasmids are key drivers of horizontal gene transfer and the spread of antimicrobial resistance. Their successful establishment in new hos…
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Reposted by Diamond Lab
Ronda lab @rondalab.bsky.social · 22/07/2025
The Ronda lab's newest publication on targeted editing: www.nature.com/articles/s41...
nature.com
Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens - Nature Biomedical Engineering
A self-transmissible CRISPR-associated transposase system encodes a nanobody payload to treat Shiga toxin infections.
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 21/07/2025
Out now in Nature Biomedical Engineering from IGI's Carlotta Ronda @rondalab.bsky.social — a novel way to precisely edit the genomes of microbes in the microbiome to defeat harmful infections. Read more: ow.ly/efsS50WsVen
innovativegenomics.org
IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing
IGI Investigator Carlotta Ronda's New Tool for Precision Microbiome Editing - Innovative Genomics Institute (IGI)
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 17/07/2025
We’re thrilled to announce IGI–Bakar Labs. This new building will allow the IGI to continue expanding our impact in health and agricultural applications of #CRISPR, and will be shared with the Bakar Labs incubator for growing biotech companies. Learn more: news.berkeley.edu/2025/07/17/c...
news.berkeley.edu
CRISPR researchers and startup entrepreneurs will share new building in UC Berkeley's Innovation Zone - Berkeley News
A planned addition to the campus's Innovation Zone will expand lab space for the Innovative Genomics Institute and build out the largest innovation hub — Bakar Labs — at any U.S. university.
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Diamond Lab @diamondlab.bsky.social · 18/07/2025
Very excited to now share publicly that @innovativegenomics.bsky.social will be expanding to an amazing new building in the 2028 - 2029 academic year! innovativegenomics.org/news/igi-bak...
innovativegenomics.org
CRISPR Researchers and Startup Entrepreneurs Will Share New Building in UC Berkeley's Innovation Zone
CRISPR Researchers and Startup Entrepreneurs Will Share New Building in UC Berkeley's Innovation Zone - Innovative Genomics Institute (IGI)
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Diamond Lab @diamondlab.bsky.social · 16/07/2025
Our friends @thehesslab.bsky.social are actively looking for postdoctoral researchers interested in anerobic microbiology, and studying the rumen microbiome. #microbiologists #bioinformatics #microbiomes Check out their website: hesslab.com
hesslab.com
Hess Laboratory – Systems Microbiology & Natural Products Research
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 09/07/2025
Out now in TIME — @jenniferdoudna.bsky.social on IGI's new initiative, teaming up with the @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures! Read here: ow.ly/E5un50WnbCi
ow.ly
The $20 Million Bet on CRISPR to Cure Rare Childhood Diseases
The center will bring custom gene-editing treatments to children.
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 10/07/2025
Hot off the presses: our reader-friendly 2025 overview of #CRISPR clinical trials! 🧬 Check it out here: ow.ly/mRPl50WneTS
graph of progress of various clinical, described in text at the link
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Diamond Lab @diamondlab.bsky.social · 11/07/2025
Click on the post for more info about the paper!!!
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Reposted by Diamond Lab
Cress Lab @cresslab.bsky.social · 26/02/2025
Dive into our lab’s first peer-reviewed publication—co-led with our friends @benadler.bsky.social and Muntathar Al-Shimary from the @doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s415... @naturemicrobiol.bsky.social
doi.org
CRISPRi-ART enables functional genomics of diverse bacteriophages using RNA-binding dCas13d - Nature Microbiology
Leveraging RNA-targeting dCas13d enables selective interference with phage protein translation and facilitates measurement of phage gene fitness at a transcriptome-wide scale.
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Reposted by Diamond Lab
Andreja Kust @andrejakust.bsky.social · 11/07/2025
🚨 Fresh from the press! We created and analyzed over 100 in vitro cyanobacterial consortia using well-characterized model cyanobacterial hosts to better understand how cyanobacteria recruit and interact with their microbiomes. Check it out: doi.org/10.1093/isme...
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Reposted by Diamond Lab
Innovative Genomics Institute @innovativegenomics.bsky.social · 10/07/2025
Out now from @diamondlab.bsky.social — stable microbiome communities using tractable cyanobacteria. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings, and microbial community ecology! Read here: tinyurl.com/3cs2x6r7
Nostoc cyanobacteria by My Microscopic World
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Diamond Lab @diamondlab.bsky.social · 10/07/2025
🥳🥳 Our work exploring the core microbiomes of stable cyanobacterial communities is now out in the @isme-microbes.bsky.social Journal!!! Excellent work by @andrejakust.bsky.social and company! #microbiology #cyanobacteria #metagenomics
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The New Yorker @newyorker.com · 09/07/2025
Globally, roughly a third more power is being generated from the sun this spring than last. If this exponential rate of growth can continue, we will soon live in a very different world, @billmckibben.bsky.social writes.
newyorker.com
4.6 Billion Years On, the Sun Is Having a Moment
In the past two years, without much notice, solar power has begun to truly transform the world’s energy system.
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Reposted by Diamond Lab
Tomas Hessler @tomas-hessler.bsky.social · 22/06/2025
We’re happy to share our preprint where applied phages to Microbiomes to test microbial interaction hypotheses - without losing the relevance of the community. Bonus: using SNPs we studied how our targeted organism recovers from infection, and find how the community likely influences this process.
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Diamond Lab @diamondlab.bsky.social · 09/07/2025
Also if you want to construct phylogenetic trees across the tree of life, also brought to you by the FoldSeek team...Unicore doi.org/10.1093/gbe/...
doi.org
Unicore Enables Scalable and Accurate Phylogenetic Reconstruction with Structural Core Genes
Abstract. The analysis of single-copy core genes, common to most members of a clade, is important for key tasks in biology including phylogenetic reconstru
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Diamond Lab @diamondlab.bsky.social · 09/07/2025
Some very nice multiple protein alignment software based on predicted structure brought to you by the folks behind #MMseqs and #FoldSeek ... Gotta try out FoldMason!! www.biorxiv.org/content/10.1...
biorxiv.org
Multiple Protein Structure Alignment at Scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
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Diamond Lab @diamondlab.bsky.social · 09/07/2025
Really fantastic paper on plasmid copy number control. Environmental plasmids are critical and surprisingly understudied tools for microbial community editing and manipulation www.nature.com/articles/s41...
nature.com
Universal rules govern plasmid copy number - Nature Communications
Plasmids exhibit a broad range of sizes and copies per cell, and these two parameters appear to be negatively correlated. Here, Ramiro-Martínez et al. analyse the copy number of thousands of diverse b...
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Diamond Lab @diamondlab.bsky.social · 09/07/2025
Hello Bluesky! Our lab is very excited to be here. This is post is a little older but is a really lovely article by the @washingtonpost.com and @shannonosaka.bsky.social about some of the work we are doing on microbiomes to combat climate change! www.washingtonpost.com/climate-solu... #microbiome
washingtonpost.com
Scientists may have found a radical solution for making your hamburger less bad for the planet
Scientists are studying how to genetically modify the makeup of cows’ gut microbiomes to prevent their planet-warming methane emissions.
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