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April Hayes

@aprilhayes.bsky.social
359 followers 502 following 46 posts

(she/her) postdoc @ Uni of Exeter in Cornwall 🌊mainly stress out bacteria and track AMR. big fan of the sea, reading, & sunsets 🌞

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Reposted by April Hayes
Clàudia Morros Bernaus @claudiamb98.bsky.social · 14/09/2026
Very happy to share the publication of the first manuscript from my PhD! 🥳 Here, we show that PCR amplification of repetitive DNA sequences, such as AMR genes flanked by insertion sequences, can lead to the generation of artefact products that need to be interpreted cautiously. (See comments 👇)
microbiologyresearch.org
PCR analysis of insertion sequences leads to the generation of artefact amplicons
Insertion sequences (ISs) are small, self-mobilizing DNA elements widespread across prokaryotic genomes, including chromosomes and plasmids. IS elements frequently co-localize with antimicrobial resis...
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Reposted by April Hayes
Sonja Blasche @sonjablasche.bsky.social · 16/07/2026
Our article "Common xenobiotics modulate gut microbial responses to low‑calorie sweeteners in vitro" is out! link.springer.com/article/10.1... With @kiranrpatil.bsky.social, @indraroux.bsky.social, @rbradley.bsky.social, @skamrad.bsky.social, @simonemozzachiodi.bsky.social, @itsbinir.bsky.social.
link.springer.com
Common xenobiotics modulate gut microbial responses to low‑calorie sweeteners in vitro - Molecular Systems Biology
The gut microbiota is implicated in adverse effects associated with low-calorie sweeteners. Yet, the direct impact of sweeteners on gut bacteria remains largely uncharacterized. Here, we report intera...
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Reposted by April Hayes
Siobhán O'Brien @siderophile.bsky.social · 29/07/2026
We rely on healthy soil microbial communities to support ecosystem functioning and plant growth, but what happens when soils are exposed to multiple environmental stressors simultaneously? Spoiler: it's not good doi.org/10.1093/isme...
academic.oup.com
Fungicide and warming interact to reduce soil ecosystem functioning
Abstract. Soil microbial communities are essential to the functioning of their ecosystems, providing vital services such as plant growth promotion and bior
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 20/07/2026
New updates to AllTheBacteria - some super cool results and an amazing resource for the community
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Dr Matt Lloyd Jones (he/him) @befriendabacterium.bsky.social · 02/06/2026
🚨 PREPRINT 🚨 In our systematic review and meta-analysis, we tackle a challenging evidence base to show that administering antibiotics to beef cattle increases the abundance of antibiotic resistance determinants (bacteria and resistance genes) during and after antibiotic administration 💊🐂 (1/n).
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Reposted by April Hayes
Marjon de Vos @lizscurious.bsky.social · 28/05/2026
Additive effects of environmental and demographic variation shape the repeatability of evolution across replicated experiments.
academic.oup.com
Additive effects of environmental and demographic variation shape the repeatability of evolution across replicated experiments
Abstract. The repeatability of evolution is fundamentally important for understanding the origin and diversification of life as well as for developing evol
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Reposted by April Hayes
Teppo Hiltunen @teppo-h.bsky.social · 28/05/2026
Evolution induced state shifts in a long-term microbial community experiment (now out, but previously posted here as a preprint) with Ville Mustonen, Lutz Becks @jcairns.bsky.social & others. Experiment continues @utu.fi and now 5+ years www.pnas.org/doi/10.1073/...
pnas.org
Evolution induced state shifts in a long-term microbial community experiment | PNAS
Biological communities are complex, dynamic systems that underpin ecosystem functionality, yet their long-term dynamics and predictability remain p...
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Reposted by April Hayes
Prajwal Padmanabha @lambdapp.bsky.social · 25/05/2026
It was a great pleasure to be a part of this and I learnt so much during the process as well! Check it out when you get some time and thanks to all the co-authors for great work! 🙌
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April Hayes @aprilhayes.bsky.social · 20/05/2026
this is super useful!
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Reposted by April Hayes
Teppo Hiltunen @teppo-h.bsky.social · 30/04/2026
New results from our synthetic communities, antibiotics & resilience project: Eco-evolutionary dynamics and environmental detoxification jointly shape bacterial community response to antibiotic perturbation www.biorxiv.org/content/10.6... Work led by @jcairns.bsky.social
biorxiv.org
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Felix M Key @keyfm.bsky.social · 30/04/2026
Can we reconstruct ancient pathogen genomes from animal remains? Can paleopathology help prioritize promising specimens? Our new paper demonstrates this by screening more than 300 specimens from across Eurasia over the past 6,000 years. www.nature.com/articles/s41...
nature.com
Probing the zooarchaeological record across time and space for ancient pathogen DNA - Nature Communications
Authors investigate ancient DNA from animal remains and identify multiple signatures of ancient zoonotic pathogens. They find ancient pathogen genomics from archaeological animal remains may inform zo...
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Cecilia Padilla-Iglesias @ceciliapad.bsky.social · 30/04/2026
🚨FULLY FUNDED PHD POSITION!🚨 If you are interested in trying to answer the question of "How did climate shape the movements, interactions, and evolution of hominin populations?" Come join my lab at @humanorigins.bsky.social 🧬🧪 deadline 7th of June ⬇️ uni-tuebingen.de/universitaet...
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Connor Sharp @magicmicrobe.bsky.social · 27/04/2026
Really excited to share a fully-funded PhD position in my lab at the University of Reading exploring how E. coli uses competition to survive in the microbiome. Perfect for anyone interested in using a mix of biochem and ecology to study pathogens. Deadline May 29th! www.findaphd.com/phds/project...
findaphd.com
Investigating how E. coli exploits bacterial competition in the microbiome at University of Reading on FindAPhD.com
PhD Project - Investigating how E. coli exploits bacterial competition in the microbiome at University of Reading, listed on FindAPhD.com
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Simon Hammann @simonhammann.bsky.social · 20/04/2026
Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.
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Ilyas Alav @ilyasalav.bsky.social · 14/04/2026
My main postdoc paper is now out in @natureportfolio.nature.com npj Antimicrobials and Resistance! www.nature.com/articles/s44.... Using flow cytometry, we show that the nucleoside analogues azidothymidine, didanosine, stavudine, and trifluridine reduced transfer of AMR plasmids pCT and pKpQIL (1/3)
nature.com
Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues
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Julia Sero @cellmorphosero.bsky.social · 09/04/2026
LLMs are like your stoner friend who is a voracious reader. They have a lot of information in their brains, but it's not necessarily in the right order, and sometimes they talk utter nonsense.
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Reposted by April Hayes
Rebecca Lowry Palmer @bexlowrypalms.bsky.social · 31/03/2026
📢 Excited to be offering a Plant Health vacation studentship this summer on plant disease biocontrol and predatory bacteria! Supervised by me at Manchester Uni! @manchester.ac.uk If interested—or know someone who might be—please share and apply! my.rsb.org.uk/services.php... 28th April deadline 🌿🍅🦠
my.rsb.org.uk
myRSB: Me and the RSB
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April Hayes @aprilhayes.bsky.social · 01/04/2026
would 100% recommend this as a PhD position to anyone interested in bacteria/temperature/amr. Dan is a great scientist to work with, and more importantly is a kind person who cares about people and (also) how science works
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Reposted by April Hayes
Stu West @stuwest.bsky.social · 04/03/2026
New paper showing that bacteria with more genes for cooperation can live in a broader range of habitats and that genes for cooperation are more more likely to be in the accessory genome www.pnas.org/doi/10.1073/... @lauriebelch.bsky.social
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Reposted by April Hayes
Microbiology Society @microbiologysociety.org · 07/03/2026
Is virulence a fixed trait? This first commentary in Microbiology Outlooks considers why it may be better understood as a context-dependent evolutionary strategy. Discover the Open Access article: doi.org/10.1099/mout.0.00001
Cover of Microbiology Outlooks featuring an article by Dr Damien Meyer on integrating game dynamics with within-host evolution genomics.
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Will Matlock @wtmatlock.bsky.social · 20/02/2026
🚨 New preprint 🚨 How promiscuous really are conjugative plasmids, and what does that mean for plasmid co-occurrence? A pleasure to collaborate with @craigmaclean.bsky.social on the first paper of my fellowship! www.biorxiv.org/content/10.6...
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Fiona J Whelan @whelanfj.bsky.social · 17/02/2026
📣 2026 PhD studentship 📣 Via @manchester.ac.uk 's President's Doctoral Scholar Awards, we are encouraging applications for a PhD on the effect of pollutant exposure on microbe-immune cross talk. This project will incorporate microbiology, immunology, & bioinformatics. Deadline: 16 March 2026!
findaphd.com
(President's Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester on FindAPhD.com
PhD Project - (President's Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester, listed on FindAPhD.c...
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Reposted by April Hayes
Michael Baym @baym.lol · 13/02/2026
He may have only barely known about bacteria, and not at all about viruses, but Darwin was right about hating an ill-defined species concept
A quote from a letter from Darwin to Hooker in 1858 reading “Oh my God how I do hate species & varieties.”
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Hannah Pugh @hannahpugh.bsky.social · 12/01/2026
The coolest finding of my PhD is finally out! E. coli has a 7th RND pump that is present in phylogroups B2/D/E/F but absent in A/B1/C. As a result EefABC has been absent in all K-12 RND studies! Co-authored by the very talented Dr. Lizzy Darby. @jessicamablair.bsky.social doi.org/10.1099/mgen...
doi.org
The Resistance-Nodulation-Division efflux pump EefABC is highly conserved within lineages of E. coli commonly associated with infection
Resistance-nodulation-division (RND) efflux pumps confer multidrug resistance in Gram-negative bacteria and are critical for many physiological functions including virulence and biofilm formation. The...
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Reposted by April Hayes
Guillaume Méric @gmeric.bsky.social · 13/02/2026
Delighted to have contributed to this impressive work led by @tovefall.bsky.social & many others👏 (w/ @gazollavolpiano.bsky.social from our side). This novel microbiome GWAS (n=~16k+12k valid) expands knowledge on genetic factors associated w/ gut microbiota variation. www.nature.com/articles/s41...
nature.com
Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation - Nature Genetics
Population-based studies from Sweden with replication in Norway identify associations between host genetic variants and gut microbial composition and implicate short-chain fatty acid chemosensors as m...
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Jesse Shapiro @bjesseshapiro.bsky.social · 09/02/2026
Now out & nicely formatted in @isme-microbes.bsky.social A big analysis of ocean genomes & metagenomes co-led by former postdocs, now PIs, @gmdouglas.bsky.social & @cyanophage.bsky.social along with co-PIs @lbobay.bsky.social & Samuel Chaffron. A few highlights... 🧵 (1/n) doi.org/10.1093/isme...
doi.org
Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny
Abstract. Understanding the drivers and consequences of horizontal gene transfer (HGT) is a key goal of microbial evolution research. Although co-occurring
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Chan Yeong Kim @chanyeong-kim.bsky.social · 09/02/2026
I am pleased to share that our paper is now published in Cell! www.cell.com/cell/fulltex... I am deeply grateful to all co-authors for making this possible. This work was made possible through the guidance of Dr. Peer Bork. I share this in grateful memory and with deep respect for his mentorship.
cell.com
Planetary microbiome structure and generalist-driven gene flow across disparate habitats
A planetary-scale analysis of over 85,000 metagenomes establishes a framework for exploring the structure and drivers of global microbial habitats, revealing that generalist species bridge ecological ...
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Will Smith @willpjsmith.bsky.social · 09/02/2026
🚨 PhD Studentship available! 🚨 We're hiring a UK student to start in Oct '26 via the BBSRC CODEM scheme. Full studentship plus £10k top-up PA. Study the mysterious ZOMBIE PHAGES 🧟 🦠 with our fabulous @mermanchester.bsky.social and @uommib.bsky.social communities! www.findaphd.com/phds/project...
findaphd.com
(CODE M) Losing your head: how do bacterial viruses evolve into anti-competitor weapons? at The University of Manchester on FindAPhD.com
PhD Project - (CODE M) Losing your head: how do bacterial viruses evolve into anti-competitor weapons? at The University of Manchester, listed on FindAPhD.com
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Sam Horsfield @samuelhorsfield.bsky.social · 07/02/2026
At long last, my final PhD chapter is out: we developed a novel evolutionary simulator of bacterial pangenomes, Pansim, fitting it to data from >600K genomes using a likelihood-free framework, PopPUNK-mod, to explore neutral and adaptive pangenome dynamics www.biorxiv.org/content/10.6...
biorxiv.org
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Ákos T Kovács @evolvedbiofilm.bsky.social · 07/02/2026
Historical contingency limits adaptive diversification in a spatially structured environment @evolletters.bsky.social from @megbehri.bsky.social academic.oup.com/evlett/artic...
academic.oup.com
Historical contingency limits adaptive diversification in a spatially structured environment
Abstract. Understanding how genotype-by-environment (G × E) interactions influence evolutionary trajectories and contribute to historical contingency is ke
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Danna Gifford @dannagifford.bsky.social · 06/02/2026
New round of PhD studentships in microbial engineering, including one with me on engineering non-canonical DNA mismatch repair into E. coli 🦠🧬 www.findaphd.com/phds/project...
findaphd.com
(CODE M) Engineering tuneable mutation processes in microbial systems via non-canonical DNA repair at The University of Manchester on FindAPhD.com
PhD Project - (CODE M) Engineering tuneable mutation processes in microbial systems via non-canonical DNA repair at The University of Manchester, listed on FindAPhD.com
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Rebecca J Hall @drrebeccajhall.bsky.social · 06/02/2026
PhD projects in microbial engineering now up, including one with @whelanfj.bsky.social @willpjsmith.bsky.social and me! 🦠 www.findaphd.com/phds/project...
findaphd.com
(CODE M) The use of synthetic communities to understand how the cystic fibrosis microbiome responds to perturbation at The University of Manchester on FindAPhD.com
PhD Project - (CODE M) The use of synthetic communities to understand how the cystic fibrosis microbiome responds to perturbation at The University of Manchester, listed on FindAPhD.com
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Sara Mitri @saramitri.bsky.social · 27/01/2026
Thrilled to see this paper finally out! journals.plos.org/ploscompbiol... It was a difficult story to communicate and took us a while to get right. Big congratulations to @wbjorn.bsky.social, Pablo Guridi and Flora Arias-Sanchez!! And thank you the reviewers who helped improve it. Keep reading...
journals.plos.org
Novel artificial selection method improves function of simulated microbial communities
Author summary Artificial selection has been extremely powerful in improving properties of complex biological or biochemical entities. The most familiar examples come from the breeding of animals and ...
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Alasdair Hubbard @dralhubb.bsky.social · 21/01/2026
🚨 Fully‑funded PhD for Home Students🚨 We'll explore non-antibiotic alternatives in relatistic environments, uncovering how they work, if they affect antibiotic activity and whether they influcence AMR acquistion. Come join a wonderful supervisory team! #MicroSky #UTISky #AMar tinyurl.com/38u552bu
tinyurl.com
Optimising the use of alternative therapies for the treatment of urinary infections - The University of Nottingham
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Stephen Heard @stephenbheard.bsky.social · 13/01/2026
It's easier to tear down than build up, and in science we have a bad case of that. So: how to lead a journal club that actually finds value in what you read. scientistseessquirre... 🧪
scientistseessquirrel.wordpress.com
How to lead a journal club you won’t be embarrassed by later
One of the jobs facing an early-career scientist, and a developing writer, is to learn what their field’s literature looks like. One of the best tools to that end is the journal club. If you’ve nev…
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Joe Jukes @joejukes.bsky.social · 15/01/2026
"84.9% of colleagues on FTCs reported that their contracts had negative impacts upon their wellbeing" ^ As long as fixed-term contracts (FTC's) are the norm for early-career scholars + many others, then our workplaces are structurally screwing us.
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Lucy van Dorp @lucyvandorp.bsky.social · 08/01/2026
There's still a few days left to apply for our AI-Intervene PhD project mapping the drivers of avian influenza using viral genomics, bird migration data and AI-powered phylodynamics. Come join us! Details below. #FindaPhD #LondonPhD #genomics
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Lars Barquist @lbarquist.bsky.social · 17/12/2025
Our preprint on predicting drug resistance in bacteria is now out in @plosbiology.org. We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. Work from @yanyingyu.bsky.social with @nwheeler443.bsky.social.
journals.plos.org
Biased sampling driven by bacterial population structure confounds machine learning prediction of antimicrobial resistance
Machine learning methods have emerged as promising tools to predict antimicrobial resistance (AMR) and uncover resistance determinants from genomic data. This study shows that sampling biases driven b...
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Prof. Ruth Ley FRS @microbiome.bsky.social · 13/12/2025
🦠🧫 a collaboration with the Institute for Tropical Medicine in Tübingen and CERMEL in Gabon @cmfi.bsky.social
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Dr. Canton Winer @cantonwiner.bsky.social · 12/12/2025
Asexuality is a global identity. That’s a major finding in a study I recently published with @francescorampazzo.com in Demographic Research. Analyzing dating app data spanning 162 countries from over 900,000 users, we found that asexuality showed up in every age group and in every region.
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Aldert Zomer @aldertzomer.bsky.social · 08/12/2025
MetaPointFinder: A new approach for detecting mutation-driven antimicrobial resistance directly from metagenomic reads. Fills a major gap in current resistome profiling by capturing chromosomal AMR mutations that metagenome tools miss. github.com/aldertzomer/...
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Daniel Podlesny @podlesny.bsky.social · 02/12/2025
We're excited to release metaTraits.embl.de! 🦠 Interactively explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes. Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
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Lisa Maier Lab | Tübingen @lisamaierlab.bsky.social · 26/11/2025
It’s not only medications—environmental chemicals can also inadvertently harm our gut microbes. Excited to have contributed a bit to this important study!
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Dr Emily May Stevenson @emilymaystevenson.bsky.social · 25/11/2025
🚨‼️ New paper alert! ‘Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments’ FULL ARTICLE: www.sciencedirect.com/science/arti... ➡️ Check out @pml.ac.uk’s coverage: pml.ac.uk/news/micropl...
pml.ac.uk
Microplastics pose a human health risk in more ways than one
New study shows that microplastics in the natural environment are colonized by pathogenic and antimicrobial resistant bacteria. The study team calls for urgent action for waste management and strongly
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Dr Emily May Stevenson @emilymaystevenson.bsky.social · 24/11/2025
Great to see our @exeter.ac.uk and @pml.ac.uk research highlighted in @uk.theconversation.com 🤟🙏 ➡️ theconversation.com/plastic-bio-...
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University of Exeter CEC @uniexecec.bsky.social · 24/11/2025
Are you looking for a wild PhD opportunity? 🦠🧵 There are several opportunities to join the Wild Microbiome Lab in 2026! Scroll for more information, or visit the link below for full project descriptions and application information👇 xavharrison.github.io
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Elze Hesse @elzehesse.bsky.social · 24/11/2025
Exciting PhD position on algal-driven metal remediation with Dr Michiel Vos and collaborators at the University of Exeter. This project combines plant and microbial ecology, and geochemistry to develop innovative biological solutions for metal pollution www.findaphd.com/phds/project...
findaphd.com
NERC RED-ALERT CDT: Green Rivers: harnessing freshwater algae for bioremediation and critical metal recovery. at University of Exeter on FindAPhD.com
PhD Project - NERC RED-ALERT CDT: Green Rivers: harnessing freshwater algae for bioremediation and critical metal recovery. at University of Exeter, listed on FindAPhD.com
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Uli Klümper @ulikluemper.bsky.social · 23/11/2025
📢 New paper in @natcomms.nature.com Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes doi.org/10.1038/s414... Thrilled to share this massive global effort led by H.M. Martiny, @patrickmunk.bsky.social, F. Aarestrup & the Global Sewage Consortium
doi.org
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes - Nature Communications
Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geogra...
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Erik Postma @erikpostma.bsky.social · 21/11/2025
A lot has happened since our first announcement of #ExE2026, an evolutionary ecology conference hosted by @uniexecec.bsky.social in #Cornwall from June 29 to July 3 2026. Have a look at our new website to see our confirmed plenary speakers, the mid-conference excursions, and more. 👉 evoxeco.uk 👈
The logo of the Evolution x Ecology 2026 conference in Cornwall, UK.
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