iiinova — where your digital self keeps evolving

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Sachin Kotak @spindlebehavior.bsky.social · 15/09/2026

Can light build centrosome-like activity? 💡🔬 Yes! We introduce LISA (Light-Induced Spindle Assembly), now in @emboreports.org. By clustering Aurora A with optogenetics, we build centrosome-like activity that nucleates microtubules and rescues spindle defects after centrosome loss. shorturl.at/9h3VQ

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Mark A. Hanson @hansonmark.bsky.social · 08/03/2025

This #InternationalWomensDay I want to tell the story of Lilian Vaughan Morgan. I learned of Lilian this past year - what a badass. Lilian was a leading scientist when women weren't welcome in the lab, nor even the department. But she contributed immensely to the genetics of sex determination 1/n

A photo of a young Lilian Vaughan Morgan, sitting with a book on her lab staring into the distance.

A photo of an older Lilian Vaughan Morgan, sitting at a lab bench with a microscope and dozens of glass milk bottles bunged with cotton. Lilian is in the middle of applying ether to anaesthetize a bottle of flies.

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sveta-lab @svetac.bsky.social · 11/02/2026

🪰🔬 Thrilled to share our latest article on Drosophila innate immunity and gut-immune interactions! Grateful for the team's hard work and excited for your thoughts! #DrosophilaResearch #InnateImmunity #GutImmuneAxis onlinelibrary.wiley.com/share/author...

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sveta-lab @svetac.bsky.social · 06/12/2025

Proud of two covers from India this year in JCB....both so beautiful, @rpadinjat.bsky.social and @spindlebehavior.bsky.social

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sveta-lab @svetac.bsky.social · 16/10/2025

Our first lab preprint — feeling like a very proud mentor today!

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sveta-lab @svetac.bsky.social · 16/10/2025

6/n After an injury, hemocytes migrate to the gut and remain there for several days, a response that relies on hemocyte Upd3. Their presence is critical for epithelial defense—flies lacking hemocyte Upd3 fail to mount this protective response and succumb to what would normally be a benign infection.

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sveta-lab @svetac.bsky.social · 16/10/2025

5/n Following injury, chronic JAK–STAT activity persisted in enterocytes and visceral muscle for ~10 days. 10xSTAT-GFP data showed that this sustained signaling required hemocyte Upd3, establishing a long-term Upd3→STAT axis in the gut epithelium.

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sveta-lab @svetac.bsky.social · 16/10/2025

4/n Injury triggers gut proliferation via hemocyte Upd3. This regenerative wave is lost in Hml>Upd3 RNAi flies, leading to premature gut aging with epithelial hyperplasia and excess enterocytes. Hemocyte Upd3 is thus essential for balanced epithelial renewal post-injury.

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sveta-lab @svetac.bsky.social · 16/10/2025

3/n The loss of Upd3 in hemocytes compromises gut barrier integrity after thoracic injury. Flies with reduced hemocyte Upd3 showed blue dye leakage into the body cavity after injury, indicating epithelial barrier failure. Thus, hemocyte Upd3 is essential for gut integrity after distant wounding.

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sveta-lab @svetac.bsky.social · 16/10/2025

2/n To examine how a local wound influences distant organs, we used a simple injury model — a prick to the thorax of adult Drosophila. We study the communication between the wound site and other tissues, and hemocytes relay systemic signals that preserve epithelial integrity beyond the injury site.

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sveta-lab @svetac.bsky.social · 16/10/2025

1/n Fly blood cells sense injury through reactive oxygen signals and release the cytokine Upd3, which activates JAK–STAT signaling in the gut to reinforce its barrier, balance cell turnover, and prevent lethal leakage. A single wound, a whole-body survival plan.

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sveta-lab @svetac.bsky.social · 16/10/2025

“When one organ is wounded, how does the rest of the body know to protect itself?” We explored exactly this question in our latest preprint 👇 🔗 www.biorxiv.org/content/10.1... #Preprint #JAKSTAT #Regeneration #Drosophila #ImmuneSignaling #GutHomeostasis

biorxiv.org

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Matt Bertone @bertonemyia.bsky.social · 10/09/2025

**Attention fly enthusiasts!** We're looking for presenters for the Dipterists Society General Meeting at ESA @entsocamerica.bsky.social in Portland, OR (November 11th) If you're interested in giving a talk, please DM me for a link to submit a title/abstract. Deadline to submit is October 10th.

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Sachin Kotak @spindlebehavior.bsky.social · 13/09/2025

Happy to share our work in @embojournal 👉 shorturl.at/zXNyn For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division? Follow this thread to know more 👇

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Dr. Tom Frieden @drtomfrieden.bsky.social · 29/08/2025

Vaccines save lives. There is no credible evidence that they cause autism. Pretending otherwise hurts kids twice – by undermining trust in vaccines, and by distracting from the urgent need to understand and address autism itself.

tomfrieden.substack.com

The Plain Truth About Vaccines and Autism

We respect families not by perpetuating recycled myths, but by pursuing real science and better care.

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Sunaina Chopra @sunainamoudgill.bsky.social · 25/07/2025

Attended an inspiring workshop on “Developing & Sustaining Your Academic Writing Practice” with @raulpachecovega.bsky.social ✏️ Full of practical tips, resources, and insight. Feeling motivated to write for once and to keep writing! 😄 #PhDLife #WritingSky #AcademicSky

A laptop sits on a table and the screen reads the following:

Dr. Raul Pacheco-Vega
Professor, Methods Lab
Facultad Latinoamericana de Ciencias Sociales (FLACSO) Mexico
raul.pacheco-vega@flacso.edu.mx
https://www.raulpacheco.org/blog

Developing and Sustaining Your Academic Writing Practice

The University of British Columbia
Faculty of Graduate and Postdoctoral Studies
July 24h, 2025
Hosts: Pathways to Graduate Success (Anjali Bauri, Jacqui Brinkman)

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sveta-lab @svetac.bsky.social · 11/07/2025

Happy to have contributed to these important papers

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Mark A. Hanson @hansonmark.bsky.social · 10/07/2025

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n

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Rockefeller University Press @rupress.org · 07/07/2025

The cover of @jcb.org's July issue (rupress.org/jcb/issue/22...) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (Adhikary et al. doi.org/10.1083/jcb....)

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sveta-lab @svetac.bsky.social · 08/07/2025

JCB July cover (hubs.la/Q03vJ8s50) shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein (hubs.la/Q03vJ8yc0). #SachinKotak lab

hubs.la

Volume 224 Issue 7 | Journal of Cell Biology | Rockefeller University Press

Journal of Cell Biology (JCB) publishes advances in any area of basic cell biology as well as applied cellular advances in fields such as immunology, neurobiology, metabolism, microbiology, developmen...

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sveta-lab @svetac.bsky.social · 28/06/2025

Congrats to your team Helena

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sveta-lab @svetac.bsky.social · 28/06/2025

🧬 Grateful to see our lab’s work featured by @India_Alliance in their Stories of Science! We use Drosophila to study how injury in one organ triggers immune/regenerative responses in another, via inter-organ communication. Honoured to share our story! www.indiaalliance.org/stories_of_s...

indiaalliance.org

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tomtom-auer.bsky.social @tomtom-auer.bsky.social · 07/05/2025

We are #hiring! Interested in comparative neuroscience? Check details here (www.unifr.ch/bio/en/depar...). We look for a motivated #PhD student or #PostDoc to combine genetics, physiology, neural circuit tracing, and behaviour to study taste processing evolution in #Drosophila. Please repost.

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sveta-lab @svetac.bsky.social · 12/04/2025

Thanks to DBT/WT India Alliance for their support over the years and enabling me to have such an awesome mentor like @irenemiguel-aliaga.bsky.social www.indiaalliance.org/news/idwgs_s...

indiaalliance.org

India Alliance - Advancing Discovery & Innovation to Improve Health

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Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · 19/03/2025

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

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sveta-lab @svetac.bsky.social · 02/04/2025

I had the pleasure to host Professor Martin Lowe, a leading cell biologist from The University of Manchester, at MIRM, MAHE- Bengaluru. His research has significantly advanced the understanding of vesicle transport, Golgi function, and intracellular trafficking. Our students esp enjoyed his visit!

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Mathieu Ferron @mathieuferron.bsky.social · 02/04/2025

Fantastic opportunity if you are interested in moving your lab to Montreal, Canada! Through this program, Chairholders will be awarded up to $1 million per year for a period of 8 years. Contact me if you are interested. www.nature.com/naturecareer...

nature.com

Canada Excellence Research Chairs (CERC) - Montréal, Quebec (CA) job with University of Montreal (UdeM) | 12838461

Canada Excellence Research Chairs (CERC)

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Alex McDougall @alexmcdougall.bsky.social · 22/01/2025

Some Marine Cell Biology for you. Migrating cell in #ascidian (Phallusia). Cell leaves (delaminates) the neural tube and migrates towards anterior end (upper left) of forming tadpole. Thanks to AscidianBioCell team and Alberto Stolfi for the lineage-specific marker of this cell.

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brunolemaitre.bsky.social @brunolemaitre.bsky.social · 20/01/2025

We are recruiting one postdoc and one PhD student to join our lab on #Drosophila #innate immunity in Lausanne (Switzerland). More info: www.epfl.ch/labs/lemaitr...

epfl.ch

Open Positions

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sveta-lab @svetac.bsky.social · 20/01/2025

All interested PhD students please apply!

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Society for the Study of Evolution @sse-evolution.bsky.social · 20/01/2025

Traveling from outside the US to attend the #Evol2025 meeting in Athens, GA, USA in June? You may be eligible for our International Travel Stipend! Apply by Jan. 31. Early meeting registration is now open for those needing visas. @evolmtg.bsky.social buff.ly/3ZEWUqe

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sveta-lab @svetac.bsky.social · 16/01/2025

Urmi from our institute MIRM, talking about Lysosomes at #M2T2 sites.google.com/view/m2t2202...

sites.google.com

M2T2 | 2025 - Speakers

Confirmed Speakers

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Féaron Cassidy, PhD @fearoncassidy.bsky.social · 10/01/2025

I’ve been saying for a long time that encouraging more girls/women(/underrepresented groups) into academia does not solve inequality @ higher ranks, which is due to the leaky pipeline ie job insecurity, high mobility onus, unconscious bias and overall lack of supports. Good but sad to see the data.

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Emily Kolenbrander Ho @emkolen.bsky.social · 07/01/2025

Have you ever wanted to *see* receptor activity in embryos? If so, our new preprint is for you! In it, we showcase a new live-cell biosensor for visualizing receptor tyrosine kinase activity in living embryos – pYtags! www.biorxiv.org/content/10.1...

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Neal Silverman @nsilvermanlab.bsky.social · 22/11/2024

With lab members Ravi Bharadwaj and Swati Jaiswal, put together this review highlighting the connectivity between transports of cyclic dinucleotides and muropeptide as well as attempted to parse the confusing literature on SLC function in the NOD1/NOD2 pathways: authors.elsevier.com/sd/article/S...

authors.elsevier.com

ScienceDirect.com | Science, health and medical journals, full text articles and books.

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The Company of Biologists @biologists.bsky.social · 27/12/2024

🧪 #DevPres webinars showcase the latest developmental biology & stem cell research. The webinars are chaired each month by a different @dev-journal.bsky.social Editor, who invites talks from authors of exciting new papers & preprints. Catch up on this year's series at bit.ly/41Tqvh8 .

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Levayer Lab @levayerr.bsky.social · 21/12/2024

Looking for a job still connected to acamedia and research ? Do you like interacting with a lot of people, outreach activity, organising scientific events ? Do you have good writing and organisation skills ? We may have a job for you👇 (permanent position) emploi.pasteur.fr/offre-de-emp... 🙏RT

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Steven Marygold @steven-flybase.bsky.social · 20/12/2024

The new Metabolic Pathway reports on FlyBase provide manually curated, high-quality gene lists and visual representations of #Drosophila #metabolic pathways, integrated with the other rich data in FlyBase. E.g., see the report for GLYCOLYSIS (flybase.org/reports/FBgg...).

flybase.org

Pathway: GLYCOLYSIS

FlyBase: a database for drosophila genetics and molecular biology

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sveta-lab @svetac.bsky.social · 20/12/2024

🌟 Exciting Opportunity Alert! 🌟 🔍 TOPIC Online Course on Understanding the Functioning of a Cell 📅 Mark your calendars: 27 - 31 Jan 2025 📝 Know More: cce.iisc.ac.in/self-support-c… Limited Seats! Last Date (updated): 26 Jan 2025 #IIScBangalore #CCE #CellBiology #CellFunction

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Jennifer Mach (she/they) @jennifermach.bsky.social · 19/12/2024

Nothing like a little #PlantScience for the holidays!

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sveta-lab @svetac.bsky.social · 05/12/2024

A highlight of the year was visiting my alma mater EPFL for the annual alumni chapters meeting organized by EPFL Alumni. The connections I made are going to definitely help me to take the Bangalore alumni chapter to the next level. Great moment to meet old friends.

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Manuel Thery @manuelthery.bsky.social · 27/11/2024

Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns. #morphogenesis doi.org/10.1073/pnas... (1/n)

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sveta-lab @svetac.bsky.social · 13/11/2024

Looking for honest feedback/reviews on the new Thunder imager from leica ...if anyone has firsthand experience using it. How does it compare to say the Zeiss Apotome 3...Thanks for your help!

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sveta-lab @svetac.bsky.social · 28/10/2024

Thanks to Indiabioscience and EMBO for the opportunity to get hands on tips and advice for effective lab management. CJ and Diana are stellar instructors.

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Pedro Vale @pfvale.bsky.social · 20/06/2024

Please repost: #BMCBiology is calling for submissions for a new Collection on " #Evolution of #Immunity" - broadly defined, including eco-immunology, comparative immunology, evolutionary dynamics of host-pathogen interactions. More details: biomedcentral.com/collections/...

biomedcentral.com

Call for papers - Evolution of immunity

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