Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...

Heimische Mücken können West-Nil-Virus übertragen. Eine Berliner Studie hat untersucht, in welchen Lebensräumen das Ansteckungsrisiko a...

Geneva, 17 May 2026 On 15 May 2026, Africa CDC alerted the continent and the global community to the growing risk of regional spread of the Ebola Virus Disease (EVD) outbreak originating from Ituri pr...

By integrating functional and structural approaches with AI-based analysis of autoantibodies against type-I IFNs, these neutralizing autoantibodies—linked to severe viral diseases in humans—are shown ...

Steroid-resistant acute graft-versus-host disease is set at disease onset and leads to distinct cell-to-cell cross-talk and immune trajectories.

In this randomized, pilot trial, we treated 83 patients with either dolutegravir or vitamin C. After 48 weeks, dolutegravir use was significantly associate

Die Mpox-Klade Ib hat im vergangenen Jahr rund 45.000 Erkrankungen in mehr als 20 afrikanischen Ländern verursacht - auch Todesfälle. Seit Anfang des Jahres sind in Deutschland Ansteckungsfälle mit di...

A deeper understanding of how tissue-localized immune cells arise and function is critical for developing mucosal vaccines. Currently, there are no mu…

Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose ...

Emerging fungal pathogens have detrimental impacts on crops, animals, and humans, however little is known about their transition to a pathogenic lifestyle. This study demonstrates that the transition ...

This prospective cohort followed 741 people with HIV switching to long-acting intramuscular cabotegravir/rilpivirine. No hepatitis B virus (HBV) incident i

Current evidence does not indicate a clinically important increase in the likelihood of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant individuals who use paracetam...

Here, the authors report within-host diversity and body site translocation dynamics in hospital samples of Pseudomonas aeruginosa and reveal that body site sharing was likely due to within-patient tra...

The low-density lipoprotein receptor family members LRP1, LRP4 and VLDLR are entry receptors for yellow fever virus.

Individuals at risk for rheumatoid arthritis exhibit inflammation and immune dysregulation before and during transition to active disease.

CMV serology in the first trimester (T1) of pregnancy relies on IgG and IgM testing, followed by IgG avidity measurement when both IgG and IgM are positive. Valacyclovir is proposed to prevent vertical transmission in maternal primary infection (MPI) during T1.

During pregnancy, innate immune mechanisms at the maternal–fetal interface are important for protecting the developing fetus from pathogens. However, excessive immune activation can be harmful to the ...

T follicular helper (Tfh) cells differentiate within T cell zones, B-cell follicles, and germinal centers (GCs), where they secrete cytokines such as IL-21 and

A large-scale proteomics study involving 53,026 individuals maps 2,920 plasma proteins to 406 prevalent diseases, 660 incident diseases, and 986 health-related traits, identifying promising biomarkers...