Nature - A landmark collection of bat genomes reveals fresh clues about the evolution of one of the world’s most unusual groups of mammals.

The Cantù Lab at LiU is focused on one important goal: to discover the mechanisms of genome regulation that drive cell differentiation and specialization during embryonic development.

The lab investigates the molecular mechanisms that control biological timing in mouse and human stem cells (Azzi & Rayon, Curr Opinions 2024; Nakanoh et al., Dev Cell 2026). The central aim of this ex...

Do you want to contribute to top quality medical research? Come and join the Andersson & Kragesteen labs at the department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet/Bio

This study introduces Corgi and Corgi+ , biology-inspired deep neural network models of regulatory DNA sequences that can generalize to unseen cell types. They accurately impute epigenomic d...

X-chromosome inactivation balances X-gene dosage between the sexes in eutherians and marsupials. The lncRNA Xist mediates X-inactivation in eutherians but is absent from marsupials. An evolutionarily ...

 Journal of Regeneration is an international peer-reviewed, Open Access journal aiming to provide a platform for the dissemination of research results on regeneration and tissue repair across phy...

YouTube video by Matteo de la Torre

Abstract. Chromatin has a complex 3D structure and diverse binding proteins that coordinate the genome’s most essential functions. Many microscopy and geno

Nature - Single-cell transcriptomics combined with morphological and ecological data show that the rapid evolutionary radiation of cichlid fishes in Lake Tanganyika was accompanied by dietary...

Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

Annevo uses deep learning to achieve unprecedented accuracy in eukaryotic gene annotation, approaching the performance of evidence-based methods.

High-sugar diets cause human metabolic diseases, yet several bird lineages convergently adapted to feeding on sugar-rich nectar or fruits. We investigated the underlying molecular mechanisms in hummin...

Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...