iiinova — where your digital self keeps evolving

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International Society of Renal Nutrition and Metabolism @isrnm-social.bsky.social · 03/08/2026

We've reopened registration for a small number of people at the Renal TNT Course at ICRNM 2026! 📅 September 15-16, 2026 📍 Berlin, Germany More about interactive Renal TNT course: www.isrnm.org/tnt Register: icrnm.aey-congresse.de/registration... Don't wait - places are (very) limited!

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Reposted by Susanne Fleig

International Society of Renal Nutrition and Metabolism @isrnm-social.bsky.social · 10/08/2026

Can nutrition help slow the progression of chronic kidney disease? Join healthcare professionals from around the world in Berlin to discuss the future of renal nutrition at #ICRNM2026. Berlin, Germany | September 15-19, 2026 Explore the full program and register: icrnm.aey-congresse.de

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Susanne Fleig @sfleig.bsky.social · 31/07/2026

Coming up soon: icrnm.aey-congresse.de the XXI. International Congress on Renal Nutrition and Metabolism 2026 in Berlin! Best meeting worldwide on renal nutrition! Check out our fantastic program! :-) Please share, register and attend! #ISRNM #renalnutrition #nephsky

icrnm.aey-congresse.de

start - ICRNM

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Joel Topf @kidneyboy.bsky.social · 25/02/2026

This is what I'm talking about regarding the anti-iron bias among the ESA pushers writing the guidelines.

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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 25/02/2026

Registration open for Seeon Angioscience Conference - hope to see many of you there!

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Bong-Ihn Koh @bikohcello.bsky.social · 05/12/2025

postdocs.yale.edu/posts/2025-1... The Koh Lab is hiring!! Please reach out to join our newly established lab as a postgraduate associate! Come help us write the first exciting chapter of our (hopefully epic) saga! #CraniofacialBM #HSCniche #Vascularbiology #Immunology #YaleStemCellCenter #YaleCMED

postdocs.yale.edu

Postgraduate Associate – Koh Lab, Yale Stem Cell Center, Department of Comparative Medicine, Yale School of Medicine

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Robert Koch-Institut @rki.de · 04/12/2025

Der Beginn der Grippewelle deutet sich an. Die aktuellen Daten im ARE-Wochenbericht zeigen, dass die ans RKI übermittelten Influenza-Fälle in den letzten zwei Wochen deutlich angestiegen sind. Personen die zur Risikogruppe gehören und bisher nicht geimpft sind, sollten dies nachholen. 👉 www.rki/are

Grafik mit blauem Rahmen und hellblauem Hintergrund. Text: „Schon gegen Grippe geimpft? Der Beginn der Grippewelle deutet sich an“. Rechts unten eine Illustration mit zwei Personen: eine Person im gelben Oberteil hält sich den Hals, daneben/hinter ihr eine Person im grünen Oberteil niest in ein Taschentuch. Unten steht: „Robert Koch-Institut“.

Grafik mit blauem Hintergrund. Überschrift: „Aktuelle Situation“. Text: „Die Aktivität akuter Atemwegserkrankungen ist auf Bevölkerungsebene und im ambulanten Bereich gestiegen und liegt auf einem moderaten bzw. hohen, aber nicht unüblichen Niveau. Die Zahl schwer verlaufender Atemwegserkrankungen ist weiter niedrig. Das ARE-Geschehen wird seit mehreren Monaten hauptsächlich durch die Zirkulation von Rhinoviren und SARS-CoV-2 bestimmt.“ Darunter ein Kasten mit Glühbirnen-Symbol und Text: „Die Influenza-Positivenrate ist in den letzten zwei Wochen deutlich angestiegen, der Beginn der Grippewelle deutet sich an. Es zirkulierten bisher hauptsächlich Influenza A(H3N2)- und A(H1N1)pdm09-Viren.“ Unten steht: „Robert Koch-Institut“.

Grafik mit blauem Hintergrund und einem runden Symbol (Globus mit Mauszeiger). Text: „Informationen zu Akuten Atemwegserkrankungen und zur aktuellen Situation findet ihr unter: rki.de/are“. Darunter ein weißer Kasten mit Überschrift „Etwas gelernt?“ und den Optionen „Liken“, „Reposten“, „Teilen“, „Speichern“. Unten steht: „Robert Koch-Institut“.

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ChemBioHub - Huber Lab @chembiohub.bsky.social · 06/11/2025

New in @science.org 🧬 What if an enzyme you thought you knew turned out to control metabolism in a completely new way? We found that NUDT5 acts as a molecular handbrake on purine synthesis, reshaping how cells make DNA building blocks and respond to cancer drugs. www.science.org/doi/10.1126/...

science.org

A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis

Folate metabolism is intricately linked to purine de novo synthesis through the incorporation of folate-derived one-carbon units into the purine scaffold. By investigating chemical and genetic depende...

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Reposted by Susanne Fleig

Petrova Lab – Vascular and Tumor Biology @petrovalab.bsky.social · 06/11/2025

❣️New in @JExpMed Proud to have contributed to the work of Cornelia Halin’s lab @ETH_en ! Single-cell & 3D imaging reveal unexpected diversity of human afferent lymphatic vessels including unique CD24⁺ valve LECs and key differences from mouse skin. rupress.org/jem/article/...

rupress.org

Transcriptomics- and 3D imaging–based characterization of the lymphatic vasculature in human skin | Journal of Experimental Medicine | Rockefeller University Press

This study reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–bas

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Reposted by Susanne Fleig

ASN Publications @asnpublications.bsky.social · 07/09/2025

Kidney dysfunction was diagnosed at 5-months postpartum in 12% of patients who had gestational diabetes mellitus. Read more in #ASNCJASN kidney.pub/CJASN0802

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Reposted by Susanne Fleig

ASN Publications @asnpublications.bsky.social · 06/09/2025

New in #ASNJASN and at #Hypertension25: In a randomized, double-blind, placebo-controlled trial, Baxdrostat reduced systolic blood pressure in patients with CKD and uncontrolled hypertension. Read more about its safety and efficacy in patients with CKD here: kidney.pub/JASN0849

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/09/2025

If you are a nephrology or kidney disease or renal professional or interested in the field - make sure you have liked/followed/pinned the nephrology feed bsky.app/profile/did:... Thanks again to @richardferro.xyz for creating & updating this! It’s a one-stop shop for nephrology needs #NephSky

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Susanne Fleig @sfleig.bsky.social · 05/09/2025

Should you, too, feel like your brain is shrinking during the winter: here is why! 👇 (now, how closely related are we really to shrews!)

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Reposted by Susanne Fleig

Hans-Joachim Anders @hjanders.bsky.social · 16/08/2025

Now open access in @ndt-era.bsky.social Anti-nephrin, anti-podocin and anti-Kirrel1 antibodies: Biological challenges and clinical implications 🧐 Clinical implementation of anti-slit diaphragm antibody testing = precision dx and tx in podocytopathies ▶️ academic.oup.com/ndt/article/...

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Hellmut Augustin @hellmutaugustin.bsky.social · 14/07/2025

Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...

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ibidi GmbH @ibidicells.bsky.social · 28/05/2025

We also congratulate Dr. Laetitia Préau from Karlsruhe Institute of Technology (KIT) and Dr.Tore Bleckwehl from Uniklinik RWTH Aachen for their outstanding presentations @cpi-exstra.bsky.social @sfb1531.bsky.social @sfleig.bsky.social #PCVB2025

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ibidi GmbH @ibidicells.bsky.social · 28/05/2025

🔬 Congrats to the 2025 #GfMVB Award Winners! 🏆 Proudly #sponsored by ibidi at “Perspectives in Cardiovascular Biology” Conference🫀 🏅Emerging Scientist: Dr. Haaglim Cho from @mpi-hlr.bsky.social 🏅Young Investigator: Dr. Julian Wagner from Universitätsmedizin Frankfurt 🔗https://zurl.co/IAJmC

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Arvind (Canchi) Conjeevaram @arvindcanchi.bsky.social · 03/05/2025

Resolution of steatohepatitis without worsening of fibrosis occurred in 62.9% in the semaglutide group & in 34.3% in the placebo group. Reduction in liver fibrosis without worsening of steatohepatitis was reported in 36.8% in the semaglutide group & in 22.4% in the placebo group tinyurl.com/338u24b2

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markusathome @markusathome.bsky.social · 02/05/2025

Our Friday-Webinar with @christ-crain.bsky.social ! We talk about diagnosis and treatment of arginine vasopressin deficiency with our expert in german language! youtu.be/jSl5K0aRTvs?...

youtu.be

Vasopressin-Mangel (ehemalig Diabetes Insipidus) - Prof. Dr. Mirjam Christ-Crain (Basel, Schweiz)

YouTube video by MARKUS at HOMe

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Reposted by Susanne Fleig

Kidney International @kidneyint.bsky.social · 28/04/2025

B cell-derived exosomal miR-483-5p and its potential role in promoting kidney function loss in IgA nephropathy doi.org/10.1016/j.kint.2025.03.019 #OpenAccess #MedSky #NephSky #SkyNeph #IgAN #IgAnephropathy

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Reposted by Susanne Fleig

Academic Europe @academiceurope.bsky.social · 04/04/2025

Job - Alert 🚑 🩺 Full Professorship for Nephrology Deadline: 2025-05-03 Location: Switzerland, Bern www.academiceurope.com/job/?id=7332 #hiring #Nephrology #medicine #biomedicine #Leadership #professor #director

academiceurope.com

Academic Europe - Full Professorship for Nephrology

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SFB 1531 @sfb1531.bsky.social · 05/04/2025

Congrats to Maria Dekrolia, Nivethitha Manickam, Leah Vanicek, and Sofia de la Puente Secades for receiving the Aletta Jacobs Award at the PCVB Meeting 2025 in Frankfurt! A well-deserved recognition of their outstanding contributions to science. #PCVB2025 #AlettaJacobsAward

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Susanne Fleig @sfleig.bsky.social · 05/04/2025

Tore Bleckwehl from Aachen presenting as a finalist in the GfMVB Emerging Scientist Award session at #PCVB2025 in Frankfurt!

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Rainer Kaiser @rainerkaiser.bsky.social · 05/04/2025

Excited to share the most recent work from our lab and results from two exciting cooperations: In this week's issue of @bloodjournal.bsky.social (ashpublications.org/blood/issue), Afra Anjum presents her cover story on how aging platelets gain inflammatory functions in the circulation. 1/4

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NEJM.org @nejm.org · 30/03/2025

Presented at #ACC25: Lepodisiran, an extended-duration, small interfering RNA, reduced lipoprotein(a) concentrations in participants with elevated levels. Full ALPACA trial results: nej.md/4kWjJyn #MedSky @accintouch.bsky.social

A graph showing the least-squares mean percent change in the lipoprotein(a) concentration from baseline through 540 days in the efficacy analysis set, which included data from participants who received at least one dose of lepodisiran or placebo, with the exclusion of data collected from participants after discontinuation of lepodisiran or placebo or initiation of medications known to affect lipoprotein(a).

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immunoboys @immunoboys.bsky.social · 30/03/2025

During inflammation, CCL21 is down-regulated in the lymph node. Enzymes for production of oxysterols are induced and recruitment of naive/central memory cells relies more in oxysterols interacting with GPR183 (+ CCL19). in 🐭 Chen et al @cellpress.bsky.social 2025 pubmed.ncbi.nlm.nih.gov/39708807/

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Joel Topf @kidneyboy.bsky.social · 30/03/2025

Finally! (Psst it was never the fluid, it was always the sodium)

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Brendon Neuen @brendonneuen.bsky.social · 29/03/2025

Cardiovascular, Kidney & Mortality Outcomes With Long-Acting Injectable & Oral GLP1-RA in T2 Diabetes An updated meta-analysis of >70,000 patients after the SOUL trial ⬇️ 14% MACE ⬇️ 14% heart failure ⬇️ 17% CKD progression ⬇️ 12% all-cause mortality diabetesjournals.org/care/article...

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Vincenza Cifarelli, PhD @cifarelliv.bsky.social · 12/03/2025

Our latest publication investigating the role of #palmitoylation in #lymphatic endothelial integrity. Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏 www.sciencedirect.com/science/arti...

sciencedirect.com

Insulin regulates lymphatic endothelial integrity via palmitoylation

Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid metabolism is associated …

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Pierre-Paul Axisa @ppaxisa.bsky.social · 25/03/2025

A bit slow on the draw, but our manuscript phenotyping multiple sclerosis patients before and after anti-CD20 treatment is out in JCI! Using scRNAseq we show that there is a myeloid expansion in both blood and CSF. In blood there's a ubiquitous TNF-NFkB signature and monocytes make more TNF post-Tx

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Dr. Smita Divyaveer, MD, DM Nephrology @divyaveerssneph.bsky.social · 21/03/2025

🆕 🥇FDA approved therapy for C3 Glomerulopathy Iptacopan : inhibitor of the alternative complement pathway by specifically binding to and inhibiting factor B #Hope for #kidney #disease #Great time to be in #Nephrology #Nephsky #Nephbluesky #Medsky #Medbluesky #Nephronuggets

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Atul Gawande @agawande.bsky.social · 13/03/2025

Nothing will kill more children than the ongoing decimation of CDC, NIH, and USAID work to lift vaccine uptake in the US and world. Child survival rose 75% in the last 50 years. Vaccines account for 40% of that. Measles vax alone was 60% of the benefit. www.thelancet.com/journals/lan...

thelancet.com

Contribution of vaccination to improved survival and health: modelling 50 years of the Expanded Programme on Immunization

Since 1974 substantial gains in childhood survival have occurred in every global region. We estimate that EPI has provided the single greatest contribution to improved infant survival over the past 50...

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Kalev Freeman @uvmtraumalab.bsky.social · 15/03/2025

Endothelial integrin acetylation regulates vascular barrier function. This suggests new therapeutic possibilities for controlling vascular permeability in disease states. #Endothelium #VascularBiology #ImmunoSky #MedSky 🧪

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American Journal of Hypertension @amjhypertension.bsky.social · 13/03/2025

Mineralocorticoid Receptor in Endothelial Cells Contributes to Vascular Endothelial Growth Factor Receptor Inhibitor-Induced Vascular and Kidney Damage academic.oup.com/ajh/article/... 🔒

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Guille Luxán @gluxan.bsky.social · 11/03/2025

What determines whether an endothelial cell becomes arterial? @saradv.bsky.social and her team had a crack at it in @elife.bsky.social and have identified a list of genetic enhancers crucial for this -> elifesciences.org/articles/102... Congratulations on this very cool study 💃🏻💃🏻 I really liked it!

elifesciences.org

Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers

Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a to...

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Susanne Fleig @sfleig.bsky.social · 09/03/2025

An alle Nephrologen und Nephrologie-Sympathisanten- macht mit bei #NephMadness! Tippspiel ohne WM. 🙂 👇

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Europe PMC @europepmc.org · 28/02/2025

Looking for the latest preprints in the #LifeSciences ? Europe PMC indexes content from 24 #preprint servers, including bioRxiv, Research Square, medRxiv and more!! 🔎 Start exploring over 907,000 preprints in one database: europepmc.org/search?query=SRC%3A%2a%20AND%20%28SRC%3APPR%29&page=1

Stacked area chart showing the cumulative number of preprints indexed by Europe PMC from 2020 to 2025. The x-axis represents the years, while the y-axis represents the cumulative number of preprints, reaching over 900,000 by 2025. Different colours represent various preprint servers, including Research Square (largest share), bioRxiv, Preprints.org, medRxiv, PsyArXiv, Authorea Preprints, SSRN, and Others. The chart highlights the steady growth of preprint publications over time.

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PEnghard @penghard.bsky.social · 02/03/2025

This works in case pubmed stays down… and it looks like a cool alternative anyway! #nephsky #science europepmc.org

europepmc.org

Europe PMCHome - Europe PMC

Europe PMC is an archive of life sciences journal literature.

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ASN Publications @asnpublications.bsky.social · 26/02/2025

A novel diet score, representing its inflammatory potential, was associated with a higher risk of developing CKD. Reducing consumption of pro-inflammatory diet may be a strategy to prevent CKD. bit.ly/CJASN0635 #ASNCJASN

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