Incidental adrenal adenomas are common, yet renin status is infrequently assessed in hypertensive patients. Emerging evidence supports a spectrum of renin-independent aldosterone excess associated wit...

In this Primer, Vaidya and colleagues review the epidemiology, pathophysiology, diagnosis, management and quality of life of patients with primary aldosteronism, an important cause of hypertension res...

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AbstractBackground. Normal-appearing adrenal glands on cross-sectional imaging may still be the source of aldosterone production in primary aldosteronism (

Abstract. Primary aldosteronism (PA) is the most common endocrine hypertension. For decades, PA diagnosis has required proving nonsuppressibility of aldost

AbstractBackground. The saline suppression test (SST) and the captopril challenge test (CCT) have traditionally been used to confirm or exclude primary ald

Pheochromocytomas and paragangliomas (PPGLs) are rare chromaffin cell-derived neuroendocrine tumors of sympathetic (catecholamine-producing) or parasympathetic (nonsecretory) origin, frequently driven...

ENDO wouldn’t be possible without the insight and expertise of the Endocrine community. Your ideas are essential to building a dynamic, forward-thinking program that reflects the full breadth of our f...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting evid...

Background: Confirmatory testing to verify the diagnosis of primary aldosteronism (PA) in patients who have an abnormal screening result is of uncertain benefit. Objective: To perform a blinded assess...

BACKGROUND: Primary aldosteronism, an endocrinopathy present in ≥10% to 25% of patients with hypertension, confers excess cardiovascular risk that can be mitigated with aldosterone-directed therapy. H...

This interactive feature describes a woman who received a diagnosis of hypertension and preeclampsia at 27 years of age. After giving birth, her blood pressure remained elevated. Test your diagnost...

BACKGROUND: The prevalence of secondary causes of hypertension in young adults is unknown, and therefore, there is no consensus about the indication of screening of secondary hypertension (2HTN) in th...