iiinova — where your digital self keeps evolving

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Guille Luxán @gluxan.bsky.social · 08/09/2026

New paper out in Cardiovascular Research! DNMT3A-driven clonal haematopoiesis promotes endothelial activation in heart failure through a semaphorin 4A–dependent mechanism 💃🏻💃🏻 Congratulations to the first author @Mariana Shumliakivska for leading this exciting work! academic.oup.com/cardiovascre...

academic.oup.com

DNMT3A-driven clonal haematopoiesis induces semaphorin 4A-dependent endothelial activation in heart failure

Mariana Shumliakivska, Inga Hemmerling, Sebastian Cremer, Klara Kirschbaum, Marina Scheller, Xue Li, Carsten Müller-Tidow, Florian Leuschner, David John, W

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Kurianlab @kurianlab.bsky.social · 19/06/2026

Seminar Alert *Lineage Tracing and Disease modeling in human embryos* Rio Sugimara, Hong Kong University When: 26. 06. 2026, 15:00 Where: H22-2, Medical faculty, Goethe University Frankfurt @riosugimura.bsky.social @cpi-exstra.bsky.social @goetheuni.bsky.social @scale-cluster-ffm.bsky.social

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Jakub Zeman @jakub-zeman.bsky.social · 28/05/2026

We're excited to welcome Leoš to Frankfurt soon! He'll be sharing fascinating insights about biological systems where start codons don't matter much, and stop codons make more sense than expected. Don't miss his talk on June 16 at Campus Niederrad! #translation Info: mbu.cas.cz/en/aktuality...

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Kurianlab @kurianlab.bsky.social · 28/05/2026

Seminar Alert: *Prof. Elena Conti* 'RNA exosome complex: Molecular Mechanisms of RNA degradation in health and disease' When: 18.06.2026, 14:00 Where: Haus 22-1 (lecture hall H22-1), Neiderad Campus (Uni KliniK), Goethe University RT🙏 @scale-cluster-ffm.bsky.social @goetheuni.bsky.social

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Guille Luxán @gluxan.bsky.social · 27/05/2026

It was super cool to present the project that I'm developing with Nina Wettschureck at the @cpi-exstra.bsky.social 2026 Retreat. And yes, that is a statement I will fight your for! #GoPericytes

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Kurianlab @kurianlab.bsky.social · 07/05/2026

www.cell.com/iscience/ful... Recovering damaged heart by reprogramming extracellular matrix after myocardial infract with hipsc derived cardiomyocyte patch @cpi-exstra.bsky.social

cell.com

Human iPSC cardiomyocyte patch transplantation modifies extracellular matrix and fibroblast behavior after myocardial infarction

Cell biology; Fibrosis; Stem cells research

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Kurianlab @kurianlab.bsky.social · 16/04/2026

Our department page has had a glow-up. New look, same obsession with heart and vascular science and RNA biology Sharper, cleaner, and much more clickable: vrc-frankfurt.de Web design credits: Manoj Kurian @goetheuni.bsky.social @cpi-exstra.bsky.social @scale-cluster-ffm.bsky.social @dzhk.de

vrc-frankfurt.de

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 15/04/2026

𝗢𝘂𝗿 𝗣𝗮𝗽𝗲𝗿 𝗼𝗳 𝘁𝗵𝗲 𝗠𝗼𝗻𝘁𝗵 𝗳𝗼𝗿 𝗠𝗮𝗿𝗰𝗵 𝟮𝟬𝟮𝟲: 𝗧𝗮𝗿𝗴𝗲𝘁𝗶𝗻𝗴 𝗳𝘂𝘀𝗲𝗱 𝗶𝗻 𝘀𝗮𝗿𝗰𝗼𝗺𝗮 (𝗙𝗨𝗦): 𝗔 𝗻𝗼𝘃𝗲𝗹 𝗮𝗻𝘁𝗶𝘀𝗲𝗻𝘀𝗲 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝘆 𝗳𝗼𝗿 𝘁𝗿𝗲𝗮𝘁𝗶𝗻𝗴 𝗶𝗱𝗶𝗼𝗽𝗮𝘁𝗵𝗶𝗰 𝗽𝘂𝗹𝗺𝗼𝗻𝗮𝗿𝘆 𝗳𝗶𝗯𝗿𝗼𝘀𝗶𝘀 𝗯𝘆 𝗞𝗮𝘁𝗮𝗿𝗶𝘆𝗮 𝗲𝘁 𝗮𝗹., 𝗦𝗶𝗴𝗻𝗮𝗹 𝗧𝗿𝗮𝗻𝘀𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝗧𝗮𝗿𝗴𝗲𝘁𝗲𝗱 𝗧𝗵𝗲𝗿𝗮𝗽𝘆 Find out more: cpi-online.de/researchofth...

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Kurianlab @kurianlab.bsky.social · 13/04/2026

It's our 12-year anniversary. Grateful to work with a great group of young scientists in those years. very proud of what we have done, and very thankful for sticking with our lab values in very tough times indebted to @erc.europa.eu @cpi-exstra.bsky.social @goetheuni.bsky.social current lab

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Kurianlab @kurianlab.bsky.social · 10/04/2026

14. RMU RNA Salon on ”RNA processing”: When: 02.06. 2026, 12:30 – 6:00 Where: Johannes Gutenberg University Mainz Keynotes: David Tollervey, University of Edinburgh, Niels Gehring, @unicologne.bsky.social @goetheuni.bsky.social @unimainz.bsky.social @cpi-exstra.bsky.social

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Kurianlab @kurianlab.bsky.social · 31/03/2026

Excited host @hohmannulrich.bsky.social from @imbmainz.bsky.social, along with @manuelkaulich.bsky.social Date: 07.04.2026 Time: 15:00 Venue: Haus 22 Seminar Room 1. (S22-1) Title: ‘Mechanistic insights into nuclear mRNA export and degradation’ @goetheuni.bsky.social @cpi-exstra.bsky.social

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Pulmonary Hypertension Association @phassociation.org · 30/03/2026

Today is #NationalDoctorsDay! Thank you to all the #doctors and #healthcare workers who work around the clock to provide the best care possible for people with #PH.

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Guille Luxán @gluxan.bsky.social · 17/03/2026

hi @tuda.bsky.social! I'll be on Thursday at the @synbio.bsky.social talking about the role of tissue stiffness on cardiac ageing and disease. Looking forward to meet y'all there =) @instcardregffm.bsky.social @cpi-exstra.bsky.social

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Guille Luxán @gluxan.bsky.social · 13/03/2026

Aaaaaaaaaaaaaand I am super proud of super @leahvanicek.bsky.social who was selected to present and blast the Young Investigator Award Session. Congratulations! @sfb1531.bsky.social @cpi-exstra.bsky.social @instcardregffm.bsky.social

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Guille Luxán @gluxan.bsky.social · 13/03/2026

Having a great time in Amsterdam at the German–Dutch Meeting of Molecular Cardiology! Thanks for the invitation to present our work, the clever questions and the engaging discussion. Really enjoyed the exchange! 💃🏻💃🏻 @sfb1531.bsky.social @cpi-exstra.bsky.social @instcardregffm.bsky.social

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Pulmonary Infections Giessen @pulmonaryinfection.bsky.social · 11/03/2026

Herold Lab is now Pulmonary Infections – Giessen. Our new name reflects our research focus on pulmonary infections and translational, clinically relevant science. We look forward to sharing updates on our work, publications, and projects.

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Pulmonary Infections Giessen @pulmonaryinfection.bsky.social · 10/03/2026

Interested in lung immunology, infection research, and hands-on lab work? We’re hiring a Technical Assistant (m/f/d) at JLU Giessen! Apply by 7 April 2026.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 09/03/2026

Paper of the Month (Feb 2026): Malainou et al. show that neutrophil-derived TNFSF14 drives loss of alveolar macrophages after influenza, increasing susceptibility to secondary pneumococcal pneumonia. Blocking this pathway improved outcomes, highlighting TNFSF14 as a potential therapeutic target.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 19/02/2026

𝗢𝘂𝗿 𝗣𝗮𝗽𝗲𝗿 𝗼𝗳 𝘁𝗵𝗲 𝗠𝗼𝗻𝘁𝗵 𝗳𝗼𝗿 𝗝𝗮𝗻𝘂𝗮𝗿𝘆 𝟮𝟬𝟮𝟲: 𝗘𝗻𝗱𝗼𝘁𝗵𝗲𝗹𝗶𝗮𝗹 𝗭𝗕𝗧𝗕𝟭𝟲—𝗮 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝘀𝗵𝗶𝗲𝗹𝗱 𝗮𝗴𝗮𝗶𝗻𝘀𝘁 𝗰𝗮𝗿𝗱𝗶𝗮𝗰 𝗮𝗴𝗶𝗻𝗴 𝗯𝘆 𝗦𝘁𝗶𝗹𝘇 𝗲𝘁 𝗮𝗹., 𝗘𝘂𝗿𝗼𝗽𝗲𝗮𝗻 𝗛𝗲𝗮𝗿𝘁 𝗝𝗼𝘂𝗿𝗻𝗮𝗹 Find out more: cpi-online.de/researchofth...

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Guille Luxán @gluxan.bsky.social · 18/02/2026

The one and only @cbodemer.bsky.social educating the audience at #EMBLCardioBiology @events.embl.org about the perils of cell culture on plastic. For details, he will be standing in front of the poster 56! 🫀💥 @instcardregffm.bsky.social @cpi-exstra.bsky.social @sfb1531.bsky.social

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Guille Luxán @gluxan.bsky.social · 16/02/2026

On my way to #EMBLCardioBiology @events.embl.org with @cbodemer.bsky.social. Please, come and visit us at posters 56 and 110. We have cool science. Ageing, pericytes, tissue stiffness and much more 💃🏻💃🏻 @instcardregffm.bsky.social @sfb1531.bsky.social @cpi-exstra.bsky.social

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 16/02/2026

Stefan Hadzic's research bridges basic biology and translational medicine, focusing on the cellular and molecular mechanisms underlying adult lung growth, resilience, and repair.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 13/02/2026

Since Fan Wu's time as a PhD student at the Max Planck Institute for Heart and Lung Research, she has been dedicated to understanding how epigenetic dysregulation contributes to lung disease.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 13/02/2026

Marius' research at the CPI aims at the investigation of the regulation and molecular consequences of tRNA supply differences across the hematopoietic and cardio-pulmonary system to ultimately inspect causality between differential tRNA expression and (pathological) changes in cell identity.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 04/02/2026

We proudly congratulate Prof. @stefaniedimmeler.bsky.social on receiving the Hector Science Prize for her outstanding scientific achievements. The award was presented during the 30th anniversary celebrations of the Hector Foundations. Read more: hector-fellow-academy.de/spitzenforsc...

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Goethe-Universität Frankfurt @goetheuni.bsky.social · 02/02/2026

🏆Prof. @stefaniedimmeler.bsky.social ( #GoetheUni & @cpi-exstra.bsky.social) erhält den mit 200.000 Euro dotierten #Wissenschaftspreis der Hector Stiftung. Ausgezeichnet werden ihre Beiträge zur interdisziplinären Herz-Kreislauf-Forschung. Congrats! | 🔗 aktuelles.uni-frankfurt.de/forschung/wi...

Zwei Personen stehen in einem festlichen Innenraum und halten gemeinsam eine gerahmte Urkunde; im Vordergrund ist ein blaues Textfeld mit der Aufschrift «Auszeichnung für Spitzenforschung in der Herz-Kreislauf-Medizin» sowie einer Beschreibung eines hoch dotierten Wissenschaftspreises und der Aufnahme in einen Forschungsförderkreis zu sehen.

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Guille Luxán @gluxan.bsky.social · 27/01/2026

If you are interested in how stiffness affects endothelial behaviour, don't miss @evborg.bsky.social online seminar tomorrow. I will present data from super @cbodemer.bsky.social. Registration: us06web.zoom.us/meeting/regi... @cpi-exstra.bsky.social @sfb1531.bsky.social @instcardregffm.bsky.social

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Guille Luxán @gluxan.bsky.social · 20/01/2026

The Molecular Medicine master students at @goetheuni.bsky.social are rotating in the labs in the context of their cardiovascular research practical courses. Today we imaged CD45+ cells in the heart. The students have produced beautiful images 💃🏻💃🏻 @instcardregffm.bsky.social @cpi-exstra.bsky.social

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Institute for Lung Health (ILH) @ilh-lunghealth.bsky.social · 12/01/2026

We’re proud to be part of a major milestone: The launch of India’s first Bioengineering Centre of Excellence for Lung Health at the IITH, in collaboration with us. This centre unites engineering & clinical science to advance interdisciplinary research, develop innovative diagnostics and therapies!

We’re proud to be part of a major milestone in lung health research!

The launch of India’s first Bioengineering Centre of Excellence for Lung Health at the Indian Institute of Technology Hyderabad (IITH), in collaboration with the Institute for Lung Health (ILH), which was represented by Prof. Werner Seeger, Prof. Soni Pullamsetti & Prof. Dr. Rajkumar Savai.

This centre unites engineering and clinical science to advance interdisciplinary research, develop innovative diagnostics and therapies, and train the next generation of lung health experts.

Together, we’re strengthening global cooperation and driving new solutions for respiratory disease challenges.

#ilh #respiratoryhealth #science #india #germany #collaboration #internationalpartnership

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 17/12/2025

🎉 Congratulations to @stefaniedimmeler.bsky.social on being awarded the Dr. Robert E. Beamish Award at the Canadian Cardiovascular Congress 2025! This award celebrates outstanding research published in the Canadian Journal of Cardiology.

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 16/12/2025

A research team at @goetheuni.bsky.social has identified a previously unrecognized type I interferonopathy, driven by reduced nitric oxide (NO) bioavailability, as a contributor to the development of atherosclerosis. Read more: cpi-online.de/paperofthemo...

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 24/11/2025

Under the motto “Let’s talk science!”, the Faculty of Medicine at Justus-Liebig-Universität Giessen once again hosted its annual Science Day. Around 160 early-career researchers, including numerous CPI Academy members, presented their research. cpi-online.de/news/science...

cpi-online.de

Successful Science Day of the Deparment of Medicine at the JLU Giessen

Under the motto “Let’s talk science!”, the Faculty of Medicine at Justus Liebig University Giessen once again hosted its annual Science Day...

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 12/11/2025

Don't miss the upcoming Science Day of the Deparment of Medicine @jlugiessen.bsky.social! Read more: cpi-online.de/news/8th-jlu...

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 10/11/2025

Alcazar et al. uncover the mechanistic link between mechanical ventilation (MV), inflammation, and arrested alveolarization of reduced alveolar epithelial cells in bronchopulmonary dysplasia (BPD). Read more: cpi-online.de/researchofth...

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 31/10/2025

Over half a million euros in DFG funding goes to Prof. Dr. Dr. Miguel Alejandre Alcazar and Dr. Julian Wagner to investigate the inter- and transgenerational metabolic priming of the neuro-cardiopulmonary interface in health and aging. Read more: cpi-online.de/news/dfg-fun...

cpi-online.de

DFG funding for Miguel Alejandre Alcazar & Julian Wagner

Awarded for research on the neuro-cardiopulmonary interface in health and aging...

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Guille Luxán @gluxan.bsky.social · 29/10/2025

Wow, that was fast @jmccardiology.bsky.social! Our article exploring the protective role of Snhg15 after myocardial infarction is already available :) www.sciencedirect.com/science/arti... Congratulations to all authors, specially to the infatigable @MarianaShumliakivska! (I'll get her to @bsky.app)

sciencedirect.com

The long non-coding RNA Snhg15 protects the heart after myocardial infarction

Cardiomyocytes are postmitotic cells that do not proliferate in the heart. In order to maintain the structural integrity of the heart, cardiomyocyte l…

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 29/10/2025

Congratulations to Dr. Marija Gredić, DZL scientist at Justus Liebig University Giessen (UGMLC), who has been awarded a €324,032 DFG research grant, investigating the role of Cathepsin D in COPD-associated pulmonary hypertension. Read more: cpi-online.de/news/dfg-fun...

cpi-online.de

DFG Funding for Marija Gredić: Investigating the Role of Cathepsin D in COPD-associated pulmonary hypertension

Dr. Marija Gredić has been awarded a research grant of € 324 032 for three years (2026–2028) from German Research Foundation (DFG) to study novel mechanisms driving pulmonary hypertension in COPD...

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Reposted by Cardio-Pulmonary Institute | CPI

Guille Luxán @gluxan.bsky.social · 27/10/2025

Look how cool, Felix Trogisch and Joerg Heineke highlight our decorin paper academic.oup.com/cardiovascre... in their last editorial in Cardiovascular Research academic.oup.com/cardiovascre.... I love the title 💃🏻💃🏻 Decorin expression is increased by ageing and contributes to inflammation and leakage.

academic.oup.com

Ageing-associated endothelial decorin induction and the impact of non-glycanated decorin on cardiac inflammation

AbstractAims. Cardiovascular disease is the leading cause of death in the European Union and ageing is one of its major risk factors resulting in the progr

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 28/10/2025

You are looking for a Postdoc position to advance your career at a world-leading institution in cardiopulmonary research? We invite you to apply for our highly competitive Postdoc Grants: cpi-online.de/uncategorize...

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Rhein-Main-Universitäten @rheinmainunis.bsky.social · 27/10/2025

Im Exzellenzcluster @cpi-exstra.bsky.social untersuchen #Forschende interdisziplinär das Zusammenspiel von Herz und Lunge, Ziel ist u.a. die Entwicklung neuartiger Therapeutika. Zum Interview mit Prof. Dr. Dr. h.c. Stefanie Dimmeler von der @goetheuni.bsky.social geht es hier: youtu.be/aik52E5AlXg

youtu.be

RMU Insights: Exzellenzcluster Cardiopulmonary Institute (CPI)

YouTube video by Rhein-Main-Universitäten (RMU)

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Guille Luxán @gluxan.bsky.social · 17/10/2025

@navbo.bsky.social 2025 starts this Sunday and the great @leahvanicek.bsky.social will be flying the colours of the @instcardregffm.bsky.social. She will present her work on HFpEF and microvascular cells. Watch out for funky pericyte stuff 💃🏻🤘🏻🫀 @cpi-exstra.bsky.social @dzhk.de @sfb1531.bsky.social

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 10/10/2025

1,25 Million Euro for neurovascular research at the @goetheuni.bsky.social receives Prof. Acker-Palmer from the prestigious Reinhart Koselleck DFG grant. In her project, she aims to investigate the hidden functions of vascular-neuronal interfaces. Read more: cpi-online.de/news/acker-p...

cpi-online.de

Prof. Dr. Amparo Acker-Palmer honored with Reinhart Koselleck DFG grant

1,25 Million Euro for neurovascular research at the Goethe University Frankfurt...

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 08/10/2025

Weyrich and colleagues profiled the plasma proteome of 20,645 men and uncovered 332 proteins whose levels track with loss of the Y chromosome (mLOY) burden. Strikingly, many of these proteins predicted incident cardiovascular disease. Read more: cpi-online.de/researchofth...

cpi-online.de

September 2025

Loss of Y chromosome: proteomic signatures in human cardiovascular disease

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Pulmonary Infections Giessen @pulmonaryinfection.bsky.social · 29/09/2025

The @cpi-exstra.bsky.social is hiring! Starting January 1, 2026, we are seeking a full-time Project Coordinator (m/f/d) in science administration at the @jlugiessen.bsky.social site in Gießen. Find the full job description here: www.pulmonary-infections.com/jobs/

The Cardio-Pulmonary Institute (CPI) is hiring!
Starting January 1, 2026, we are seeking a full-time Project Coordinator (m/f/d) in science administration at the Justus Liebig University Giessen site in Gießen.
In this role, you will support the cluster’s speaker with administrative tasks, coordinate events such as seminars and workshops, communicate with researchers and funding bodies, and contribute to science communication. Applicants should hold a university degree in natural sciences, medicine, or veterinary medicine, have experience in research management, and possess excellent proficiency in both German and English. Flexible working options, mobility ticket, and further training opportunities are included. Apply by October 23, 2025.

Find the full job description here:
https://lnkd.in/e_-EiT8X

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Cardio-Pulmonary Institute | CPI @cpi-exstra.bsky.social · 25/09/2025

🚀 Call for Applications - CPI Postdoc Grants You want to shape the future of heart and lung research? We are seeking talented, ambitious postdocs to join our interdisciplinary team of over 200 scientists. Deadline: Oct 31! Details and how to apply: cpi-online.de/academy-post... #ResearchGrant

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Guille Luxán @gluxan.bsky.social · 22/09/2025

And the Microvasculature and Extracellular Matrix in cardiac ageing and disease Spain Tour 2025 comes to an end with a visit to @cicbiogune.bsky.social. Thank you very much for having me, it has been a blast 💃🏻 @instcardregffm.bsky.social @cpi-exstra.bsky.social @sfb1531.bsky.social

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Guille Luxán @gluxan.bsky.social · 19/09/2025

@leahvanicek.bsky.social and I are back at the @instcardregffm.bsky.social after a fantastic week visiting @jldelapompa-cnic.bsky.social at @CNIC. Always a pleasure to collaborate with them and a real joy to reconnect with so many good old friends!💃🏻🫀🤘🏻 @cpi-exstra.bsky.social @sfb1531.bsky.social

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