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Sebastian Bitzenhofer

@sebbitzenhofer.bsky.social
103 followers 124 following 1 posts
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Reposted by Sebastian Bitzenhofer
allen institute @alleninstitute.org · 08/10/2026
Scientists at Seattle Hub for Synthetic Biology just built the largest cellular family tree ever for a mammal, tracing how a single egg divided into 1.28 million cells. bit.ly/4zqcRjh
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Reposted by Sebastian Bitzenhofer
Matthijs Dorst @mattneuro.dorst-lab.org · 03/10/2026
Last year, Janos Fuzik and I organized a symposium on voltage imaging for the @fens.org regional meeting in Oslo. We then teamed up with our speakers to write a review on this. I am very happy to share that this review is now out in #EJN! #neuroscience 🧠 onlinelibrary.wiley.com/share/author...
onlinelibrary.wiley.com
Advances and Applications in Population Voltage Imaging
Reader environment loaded
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Natalie Schaworonkow @nschawor.bsky.social · 17/09/2026
currently preparing for a Bernstein pre-conference workshop that I co-organized with @neuralnestbird.bsky.social. we will be looking at different electrophysiological signatures (= 〰️〰️〰️) across species. come by and say hi if you are there. 🙂 bernstein-network.de/bernstein-co...
Bernstein Workshop 2026
Bridging the species divide:
 
comparative approaches to study neural signatures
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Reposted by Sebastian Bitzenhofer
Julijana Gjorgjieva @gjorjulijana.bsky.social · 23/08/2026
Supper happy to see this published. In short, we show how dendrites and inhibition allow neural circuits to learn new representations while protecting representations that are already stored in the network. See below for a detailed post by @cmiehl.bsky.social: www.sciencedirect.com/science/arti...
sciencedirect.com
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Anthony Ramnauth @philoneurosci.bsky.social · 18/08/2026
"...isolated synaptic inputs have a minimal contribution to somatic depolarization, whereas coincident inputs within short temporal windows are more effective" Highly attenuated #dendritic propagation of isolated #synaptic potentials in vivo | Science Advances www.science.org/doi/10.1126/...
science.org
Highly attenuated dendritic propagation of isolated synaptic potentials in vivo
The integration of synaptic inputs is a fundamental function of neurons. In the traditional model, excitatory inputs are summed at the soma to generate action potentials. However, how synaptic inputs ...
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Reposted by Sebastian Bitzenhofer
Matteo Carandini @carandinilab.net · 17/08/2026
I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...
doi.org
Some Tips for Writing Science
When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...
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Reposted by Sebastian Bitzenhofer
Yale Neuroscience @yaleneuro.bsky.social · 04/08/2026
📢 Calling all senior neuro postdocs: SYNAPSES brings postdocs from around the world to Yale to share their work during an in-person symposium on October 22, 2026. Apply today! Deadline Sept 3. medicine.yale.edu/neuroscience...
"Symposia at Yale Neuroscience: Advanced PoStdoc Extramural Series call for applications flyer. Deadline Sept 3, 2026, symposium October 22, 2026. Who: Senior postdocs from any area of neuroscience.
What: A symposium for advanced postdoctoral research.
Why: Present your research. Expand your network. Engage with the Yale Community."
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Emre Yaksi @emreyaksi.bsky.social · 02/07/2026
I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.
science.org
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...
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Reposted by Sebastian Bitzenhofer
Mattia Chini @mattiachini.bsky.social · 02/06/2026
What happens when 18 teams of expert neuroscientists analyze the exact same neurophysiology dataset? You might expect convergence, but that is not what we found. Very grateful for the opportunity to write with Gaëlle Chapuis about one of my favorite projects since I started working in science! 1/n
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The Transmitter @thetransmitter.bsky.social · 01/06/2026
A hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
thetransmitter.org
18 teams analyzed a neuro dataset and got different answers
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
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neuromurphy.bsky.social @neuromurphy.bsky.social · 28/05/2026
Come join the lab @maynoothuniversity.ie and work with me and stellar collaborators @seanfw.bsky.social and @redmondoconnell.bsky.social! Exciting project at the intersection of multi-task RNNs, compositional cognition and human decision neuroscience. Details and how to apply at shorturl.at/FsTQ0
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Tobias Ackels @tobiasackels.bsky.social · 12/05/2026
🚨 Preprint alert! 🚨 How does the olfactory bulb transform overlapping sensory inputs into representations that are easier to distinguish? New study by Sina Tootoonian, Yikai Yang, @andreas-t-schaefer.bsky.social @crick.ac.uk and myself.‬ www.biorxiv.org/content/10.6... A short 🧵 below
biorxiv.org
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Eduardo Maristany de las Casas @maristanye.bsky.social · 08/05/2026
1/10 When the going gets tough, the dendrites get going. Here is a summary on our new paper just published in @science.org on flexible learning in frontal motor cortex. With @mattlark.bsky.social 🔬. #neuroskyence #neuroscience 🔗 doi.org/10.1126/scie...
doi.org
Tuft dendrites in frontal motor cortex enable flexible learning
Flexible learning relies on integrating sensory and contextual information to adjust behavioral output in different environments. The anterolateral motor cortex (ALM) is a frontal area critical for ac...
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Reposted by Sebastian Bitzenhofer
Matteo Guardamagna @matteoguardamagna.bsky.social · 11/03/2026
1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵
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Johanna Joyce @johannajoyce.bsky.social · 22/04/2026
What should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪
linkedin.com
#erc | Johanna Joyce
What should Europe do when demand for its most successful frontier research programme keeps rising? Restrict access, or invest in the excellence it has created? A new open letter, spearheaded by Sara...
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The Transmitter @thetransmitter.bsky.social · 21/04/2026
In this month’s “Liftoff,” @laurenkreeger.bsky.social says she’ll encourage lab members to share “away from the bench” slides at lab meetings, and @mattiachini.bsky.social talks about his love for outdoorsy lab retreats. #neuroskyence By @franciscorr25.bsky.social bit.ly/42pdL0E
bit.ly
Liftoff: New lab alerts
Learn about early-career scientists starting their own labs.
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Reposted by Sebastian Bitzenhofer
Randolph Helfrich @randolph-helfrich.bsky.social · 20/04/2026
Does aperiodic activity index neural excitability? Single-unit and LFP recordings during optogenetic interneuron suppression show that aperiodic activity scales with firing, but it depends on context and oscillatory power. New preprint with @juliaveit.bsky.social. www.biorxiv.org/content/10.6...
biorxiv.org
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Simon Wiegert @simwieg.bsky.social · 08/04/2026
www.nature.com/articles/s41... Two-author papers are always special. Using optogenetic stimulation of hippocampal synapses in awake mice and tracking them over approx. 2 weeks, we link synaptic strength, spine volume and their stability. It's confirmed: bigger spines are stronger and more stable 😅
nature.com
Functional synaptic connectivity shapes spine stability in the hippocampus - Nature Communications
In this study, the authors find that synaptic strength predicts spine size and long-term stability via in vivo imaging together with optogenetic stimulation in awake mice. While individual synapses sh...
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Mattia Chini @mattiachini.bsky.social · 07/04/2026
Final stop for Con2Phys: Barcelona! After two amazing editions at COSYNE and Bernstein, we’re doing one last collaborative team-based hackathon. Open to all, but spots are limited. Registration opens on April 9, put it in your calendar! 👇😱 #Brainhack #OpenScience #Neuroscience #Fens2026
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Mattia Chini @mattiachini.bsky.social · 17/03/2026
New paper out in PLOS Computational Biology! We introduce iSTTC, a robust method to estimate intrinsic neural timescales from single-unit recordings. Congrats to Irina Pochinok for leading the project! Package: github.com/iinnpp/isttc Paper: journals.plos.org/ploscompbiol...
github.com
GitHub - iinnpp/isttc: iSTTC: intrinsic neural timescales estimation
iSTTC: intrinsic neural timescales estimation. Contribute to iinnpp/isttc development by creating an account on GitHub.
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Reposted by Sebastian Bitzenhofer
Kate Jeffery @katejj.bsky.social · 19/03/2026
It is absolutely astonishingly impressive how much work scientific publishers have managed to shunt onto authors, who aren't paid, while they continue to increase their enormous profits. The submission process itself takes about 5 hours. I miss the 90s 😢
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Richard Gao @rdgao.bsky.social · 12/03/2026
For this year's Neuromatch Computation Neuroscience course, the Curriculum Team is adding a new Day 🥁🥁🥁 Time series analysis and signal processing! We're looking for 5-10 content contributors with relevant neuro+DSP experience for various tasks: co-Day Lead, video, slides, code tutorials, etc.
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Scott Rich, Ph.D. @richcompneuro.bsky.social · 02/03/2026
1/5 Big news: the pre-print for my final postdoc paper is (finally) out! Why did it take so long? We significantly expanded the manuscript thanks largely to the incredible work of one of my first undergraduates here at @uconn.bsky.social @uconnresearch.bsky.social 😀 www.biorxiv.org/content/10.6...
biorxiv.org
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Earl K. Miller @earlkmiller.bsky.social · 02/03/2026
I give you Principles for Proper Peer Review jocnf.pubpub.org/pub/qag76ip8...
jocnf.pubpub.org
Principles for proper peer review
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Paul Anastasiades @panastasiades.bsky.social · 18/02/2026
New preprint from the lab on synapse development in the nascent neocortical hierarchy! Using mice that label MAGUK proteins developed by Seth Grant we find key differences in the laminar maturation of association and sensory motor cortices, including delayed, cortex-wide maturation of L1 synapses.
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Tobias Ackels @tobiasackels.bsky.social · 01/02/2026
We study how the olfactory system performs stimulus selection and figure–background segregation under naturalistic odour conditions. Looking for a PhD in neuro/bio/physics with experience in systems neuroscience & solid quantitative skills. 💼 3 years, TV‑L E13 📧 Apply: tobias.ackels@ukbonn.de​
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Tobias Ackels @tobiasackels.bsky.social · 01/02/2026
Postdoc position in systems neuroscience! Excited to recruit a postdoc for my lab at the University of Bonn. 🔬 In vivo physiology (Neuropixels, 2P/miniscope) 🐭 Head-fixed & freely moving behaviour 💡 Optogenetics/chemogenetics ⏳ Start: ASAP | Application deadline: 28.02.2026 More info below ⬇️
The research group “Sensory Dynamics and Behaviour” of Prof. Dr. Tobias Ackels at the Institute of Experimental Epilepsy and Cognition Research at the
University Hospital Bonn invites applications for a position as:
Postdoctoral Researcher (m/f/d)
The position is initially limited to three years (TV-L E13/100%),
starting from April 2026 or as soon as possible.
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Natalie Schaworonkow @nschawor.bsky.social · 16/01/2026
main goal for this year: find a new job! 🙂 looking for a role with fun & complex technical challenges & within a great community. my main expertise is in signal processing/EEG/MEG, but topic-wise I am quite flexible. science/industry both great! starting mid-year. nschawor.github.io/cv
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Mattia Chini @mattiachini.bsky.social · 09/01/2026
📣 Pre-COSYNE Brainhack 2026 – Join Us in Lisbon! 🧠✨ March 10–11, 2026 • Lisbon, Portugal pre-cosyne-brainhack.github.io/hackathon2026 Kick off COSYNE week with two days of hands-on, team-based hacking around real electrophysiology data! ✅ Apply now via the event website (limited spots).
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Mattia Chini @mattiachini.bsky.social · 12/01/2026
🚨This was not supposed to be a Friday news dump. Come join us at the pre-COSYNE hackathon! And if can’t make it to the hackathon, don’t overthink it. Start working on the full CON2PHYS project: mchini.github.io/con2phys/ Remember that submissions will be eligible for co-authorship!
mchini.github.io
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Tatjana Tchumatchenko @tatjanat.bsky.social · 10/01/2026
Please spread the word🔊My lab is looking to hire two international postdocs. If you want to do comp neuro, combine machine learning and awesome math to understand neural circuit activity, then come work with us! Bonn is such a cool place for neuroscience now, you don't want to miss out.
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Eiko Fried @eikofried.bsky.social · 07/01/2026
After 5 years of data collection, our WARN-D machine learning competition to forecast depression onset is now LIVE! We hope many of you will participate—we have incredibly rich data. If you share a single thing of my lab this year, please make it this competition. eiko-fried.com/warn-d-machi...
eiko-fried.com
WARN-D machine learning competition is live » Eiko Fried
If you share one single thing of our team in 2026—on social media or per email with your colleagues—please let it be this machine learning competition. It was half a decade of work to get here, especi...
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Open Ephys @open-ephys.org · 28/11/2025
Tired of looking at obscure headstage pinouts to figure out which channel is which? 😵 We’ve launched the 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗠𝗮𝗽𝘀 𝗱𝗼𝗰𝘀 to save you time! ⏱️ Now you can easily picture the channel maps of all headstages and connections to compatible adapters and EIBs designed by us. #OpenEphys
open-ephys.github.io
Home — Channel Maps
Here you can find the specifications and channel mapping for all the headstages, adapters and EIBs produced by Open Ephys that are available through the Open Ephys Store.
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Matthijs Dorst @mattneuro.dorst-lab.org · 26/11/2025
When you join a lab to do some voltage imaging
An old record player set by the side of the road, with a note reading: "does not work but could be fun to fix!"
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Manfredi Castelli @manfredic.bsky.social · 02/10/2025
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social ! With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
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Jonas Wietek @jwietek.bsky.social · 11/09/2025
www.science.org/doi/10.1126/... From the one and only @oyiz.bsky.social lab
science.org
Oxytocin signaling regulates maternally directed behavior during early life
Oxytocin is essential in shaping social behavior across the lifespan. Although the role of oxytocin signaling in parental care has been widely investigated, little is known about its function in socia...
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Alessandro Gozzi @gozziale.bsky.social · 10/09/2025
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience ➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism? Check out what we found! 🧵1/n
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Mattia Chini @mattiachini.bsky.social · 27/08/2025
Thanks to the support of the F.R.S. - FNRS, I’m hiring two postdocs to help kickstart the lab. Informal inquiries are welcome via socials or email. More about the two postdoc positions and how to apply: www.chinilab.com/opportunitie... RT for visibility are greatly appreciated! 🙏
chinilab.com
Chini Lab
Chini Lab at GIGA–ULiège. We study how neural activity emerges in early development from a systems neuroscience perspective.
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Mattia Chini @mattiachini.bsky.social · 27/08/2025
I am thrilled to share that this winter I will be starting my lab in the GIGA Institute of @universitedeliege.bsky.social! The lab will study early brain development at the intersection of systems and computational neuroscience. 🌐 You can find out more on the lab website: www.chinilab.com 1/2
chinilab.com
Chini Lab
Chini Lab at GIGA–ULiège. We study how neural activity emerges in early development from a systems neuroscience perspective.
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Ivan Manzini @xenofrog.bsky.social · 22/08/2025
🚨 We are looking for 2 PhD students! 🧠🐸👃 Join the Manzini Lab @jlugiessen.bsky.social to explore the olfactory system in #aquatic #vertebrates. We mainly use #amphibians, combining: 🔬 Imaging 👩‍🔬 Cell biology 🐝 Behavior 👉 bit.ly/neurophd 🌍 bit.ly/manzinilab Please share! #PhD #neuroscience #job
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Irina Pochinok @irinapochinok.bsky.social · 05/08/2025
New preprint is out! We present iSTTC, a robust method for estimating intrinsic neural timescales (ITs) from single-unit activity. It’s accurate, stable, and works even when data is sparse. doi.org/10.1101/2025...
doi.org
iSTTC: a robust method for accurate estimation of intrinsic neural timescales from single-unit recordings
Intrinsic neural timescales (ITs) are an emerging measure of how neural circuits integrate information over time. ITs are dynamically regulated by behavioral context and cognitive demands, making them...
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Oscar Marín Lab @marinlab.bsky.social · 16/07/2025
1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social @wellcometrust.bsky.social
cell.com
A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons
Neuronal activity triggers PGC-1α-mediated transcriptional programs that drive the late maturation of PV+ interneurons, essential for cortical circuit function. PGC-1α partners with ERRγ and Mef2c to ...
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Edvard I Moser @edvardmoser.bsky.social · 26/06/2025
Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...
science.org
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
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Takaki Komiyama @takakikomiyama.bsky.social · 20/06/2025
Our new paper is out in Science. We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change. Congrats to Bin for the great thesis, and the team! www.science.org/doi/10.1126/...
science.org
Cholinergic feedback for modality- and context-specific modulation of sensory representations
The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...
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Sebastian Bitzenhofer @sebbitzenhofer.bsky.social · 18/06/2025
A while back, we noticed unexpectedly high Disc1 expression in the developing olfactory bulb. We found that disrupting Disc1 alters early OB activity, which plays a key role in shaping the maturation of memory-related brain circuits. www.jneurosci.org/content/45/2...
jneurosci.org
Developmental Olfactory Dysfunction and Abnormal Odor Memory in Immune-Challenged Disc1+/− Mice
Neuronal activity in the olfactory bulb (OB) drives coordinated activity in the hippocampal–prefrontal network during early development. Inhibiting OB output in neonatal mice disrupts functional devel...
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Matteo Carandini @carandinilab.net · 17/06/2025
I'd like to make a list of PhD programs that (1) are in Europe (which does include the UK); (2) offer opportunities in systems neuroscience; and obviously (3) pay a stipend. Please share and/or respond to add your suggestions?
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Natalie Schaworonkow @nschawor.bsky.social · 16/06/2025
I signed up to post this week for @realscientists.de (in German 😬), so let's see how that goes 🙂
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Butt Lab - Oxford @interneuron.bsky.social · 06/06/2025
Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms. We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.
Image of a coronal section through postnatal mouse somatosensory cortex (S1BF with transient expression of the serotonin transporter in thalamic afferents shown in red.
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Friedemann Zenke @fzenke.bsky.social · 27/05/2025
1/6 Why does the brain maintain such precise excitatory-inhibitory balance? Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning. www.biorxiv.org/content/10.1... led by @jrbch.bsky.social
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