Sign in

Scott Pluta

@scottrpluta.bsky.social
127 followers 160 following 25 posts

Striving to understand the relationship between brain and behavior. Would rather be in Iceland. 📷🏔️

PostsRepliesMedia
Reposted by Scott Pluta
Mark Histed @markhisted.org · 02/07/2026
The reason the US has such a powerful science and innovation ecosystem is simple: decades of public investment (via largely independent agencies, including NIH and NSF). Basic science builds future cures over a timeline too long for the private sector. /3 www.infotimes.us/basic-scienc...
infotimes.us
Basic Science Is The Foundation Of Future Cures
Injecting partisan politics into American basic science would be terrible for the US: for the economy, and for development of future treatments for diseases like schizophrenia and Alzheimer's.
416762
Reposted by Scott Pluta
The Monarch Diaries @monarchdiaries.bsky.social · 20/05/2026
HAHAHAhaha! they're making the world's biggest synthetic scum pond!!! The coating is a polyurea used inside pipes. It gels in about 3 seconds, making it non self-leveling. The texture is like an orange peel, the perfect substrate for biofilms. www.nytimes.com/2026/05/19/u...
nytimes.com
Manager at Trump’s N.J. Golf Club Helped Plan Reflecting Pool Repairs
694141806
Scott Pluta @scottrpluta.bsky.social · 27/04/2026
media.tenor.com
a man in a blue uniform stands in a field of tall grass
ALT: a man in a blue uniform stands in a field of tall grass
010
Scott Pluta @scottrpluta.bsky.social · 27/04/2026
media.tenor.com
a man with a beard is driving a car with his arm out the window .
ALT: a man with a beard is driving a car with his arm out the window .
030
Reposted by Scott Pluta
Michael Lin, MD PhD @michaelzlin.bsky.social · 01/02/2026
Today I'd like to honor the memory of my mentor and friend, Roger Tsien, born 1952 February 1. Today would have been Roger's 74th birthday. Most know Roger for his 2008 Chemistry Nobel Prize with Shimomura and Chalfie. Roger made GFP into the versatile imaging method it is now.
312023
Reposted by Scott Pluta
Kelsey Tyssowski @kelseytea.bsky.social · 22/10/2025
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity! We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have: (1) more corticospinal neurons (CSNs) (2) better hand dexterity (3) more dexterous climbing, which is linked to CSN number🧵
19380124
Scott Pluta @scottrpluta.bsky.social · 24/09/2025
And maybe an espresso, too?
110
Scott Pluta @scottrpluta.bsky.social · 23/09/2025
Pretty tired from a 12km loop yesterday from highland base camp to Hveradalir in Kerlingarfjöll. Worth the pain, though.
130
Reposted by Scott Pluta
Oded Rechavi @odedrechavi.bsky.social · 10/09/2025
Full professor complaining to an assistant professor on how hard it is to get funding nowadays
220426
Scott Pluta @scottrpluta.bsky.social · 11/07/2025
There isn't a self-generated (optic flow coupled to locomotion) stimulus in these datasets, which I believe is the crux of the Keller lab argument. But, there are many studies showing enhanced activity to the oddball. I've not a fan of that approach. Sensory predictions are driven by movement, IMO.
0130
Reposted by Scott Pluta
Aaron Milstein @neurosutras.bsky.social · 08/07/2025
This will devastate all of my colleagues that do neuroscience in mice. Drugs don't always translate from mouse to human, But 90% of our genes are shared. They allow recordings and manipulations that cannot be done in humans. We will cede discovery to Europe and China with this unnecessary handicap.
drugdiscoverytrends.com
NIH announces end to funding for animal-only studies - Drug Discovery and Development
Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.
35422
Scott Pluta @scottrpluta.bsky.social · 16/06/2025
What are the needs of humanity?
101
Scott Pluta @scottrpluta.bsky.social · 09/06/2025
Very interesting. I was hoping you would say something about this impending manuscript, tho.
010
Scott Pluta @scottrpluta.bsky.social · 09/06/2025
Manuscript? 👀
101
Reposted by Scott Pluta
Adam Sternbergh @sternbergh.bsky.social · 05/06/2025
must be incredibly frustrating and disheartening to have federal funding that was promised to you for important work suddenly and arbitrarily ripped away
608349968049
Reposted by Scott Pluta
Kate Jeffery @katejj.bsky.social · 02/06/2025
UK neuroscience graduates! PhD opportunity here at Glasgow SPN: www.findaphd.com/phds/project... Closing date July 4
findaphd.com
Converting percepts into actions in the visual cortex and superior colliculus. at University of Glasgow on FindAPhD.com
PhD Project - Converting percepts into actions in the visual cortex and superior colliculus. at University of Glasgow, listed on FindAPhD.com
164
Reposted by Scott Pluta
Jimmy Dooley @jimmycdooley.bsky.social · 30/05/2025
In late January, I said we were "still exploring" a cool thing we found in RN. Well, we're back, and we've got movement kinematics (thanks to ‪@deeplabcut.bsky.social‬)! (You can find all the details in our updated bioRxiv paper, linked below) www.biorxiv.org/content/10.1...
biorxiv.org
Subcortically generated movements activate motor cortex during sleep and wake in rats through postnatal day 24
During early postnatal life, cortical motor control emerges from complex interactions between cortical and subcortical circuits. Although activity dependent processes are essential for primary motor c...
194
Reposted by Scott Pluta
The Transmitter @thetransmitter.bsky.social · 26/05/2025
Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration, writes @neuralreckoning.bsky.social. #neuroskyence www.thetransmitter.org/funding/neur...
thetransmitter.org
Neuroscience needs to empower early-career researchers, not fund moon shots
Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration.
313444
Reposted by Scott Pluta
@LaBonneLaB @labonnelab.bsky.social · 19/05/2025
It is beyond disturbing when the NIH and HHS Directors do not understand that animal models are essential in research www.statnews.com/2025/05/19/a...
statnews.com
There is no replacement (yet) for animal models in medical research
The NIH is “reducing animal use in research.” But there is no replacement for animal models.
112250
Scott Pluta @scottrpluta.bsky.social · 17/05/2025
Other great examples are in the whisker system where the sensory nerve is cut, but movement signals persist. Such as pubmed.ncbi.nlm.nih.gov/40011781/
pubmed.ncbi.nlm.nih.gov
Brain-wide presynaptic networks of functionally distinct cortical neurons - PubMed
Revealing the connectivity of functionally identified individual neurons is necessary to understand how activity patterns emerge and support behaviour. Yet the brain-wide presynaptic wiring rules that...
020
Scott Pluta @scottrpluta.bsky.social · 17/05/2025
Ideally, you eliminate sensory feedback during the movement, allowing you to observe the residual motor efference. The best example is in weakly electric fish. Nathan Sawtell and Curtis Bell is a place to look in that regard.
120
Reposted by Scott Pluta
Hayley Bounds @hayleybounds.bsky.social · 15/05/2025
Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).
511336
Reposted by Scott Pluta
Nature Neuroscience @natneuro.nature.com · 16/05/2025
Bilateral integration in somatosensory cortex is controlled by behavioral relevance 🧠🧪 @scottrpluta.bsky.social www.nature.com/articles/s41...
nature.com
Bilateral integration in somatosensory cortex is controlled by behavioral relevance - Nature Neuroscience
How sensory signals from both sides of the body are integrated into a single percept is not well understood. Park et al. show that callosal signaling supports the integration of bilateral tactile stim...
0103
Scott Pluta @scottrpluta.bsky.social · 15/05/2025
How is this not obvious to everyone but maybe a first year student? The brain can hallucinate, but calling that hallucination information might be a stretch.
030
Scott Pluta @scottrpluta.bsky.social · 14/05/2025
I'm really proud of my two graduate students, Hyein and Hayagreev, for getting this challenging and exciting project across the finish line. We reveal the state-dependent logic that underlies callosal signaling between the somatosensory cortices. www.nature.com/articles/s41...
nature.com
Bilateral integration in somatosensory cortex is controlled by behavioral relevance - Nature Neuroscience
How sensory signals from both sides of the body are integrated into a single percept is not well understood. Park et al. show that callosal signaling supports the integration of bilateral tactile stim...
083
Reposted by Scott Pluta
Ian Oldenburg @ianoldenburg.bsky.social · 13/05/2025
The Oldenburg lab is looking for another postdoc! If you want to use holographic optogenetics to answer questions about neural codes let me know. We like shooting lasers and thinking about movement. We're located at Rutgers in Piscataway NJ (its like ~45 min from NYC). oldenburglab.com/positions/
oldenburglab.com
Positions
Join the lab We are looking for curious, motivated, and talented people from all different backgrounds to join our team at all levels. Mentoring is simply one of the best parts of being an academic sc...
1104
Scott Pluta @scottrpluta.bsky.social · 02/05/2025
May 2021, shortly after we finished building automated boxes for training mice to perform bilateral discrimination using active touch. The first paper is finally dropping soon.
010
Reposted by Scott Pluta
PLOS Biology @plosbiology.org · 20/04/2025
Our latest editorial in defense of vaccines and vaccination, introduces two Perspectives in this issue on priorities for outbreak vaccination, as well as the important successes of vaccines to date Please read and spread the word 🙏🏻!
15539
Reposted by Scott Pluta
Earl K. Miller @earlkmiller.bsky.social · 21/04/2025
New results! Evidence for an active handoff between cerebral hemispheres during target tracking www.biorxiv.org/content/10.1... #neuroscience
biorxiv.org
Evidence for an active handoff between cerebral hemispheres during target tracking
The brain has somewhat separate cognitive resources for the left and right sides of our visual field. Despite this lateralization, we have a smooth and unified perception of our environment. This rais...
0236
Reposted by Scott Pluta
Lauren Kreeger @laurenkreeger.bsky.social · 18/04/2025
Thrilled that our paper has been published in @elife.bsky.social doi.org/10.7554/eLif... We ask: how can a neuron integrate information across multiple time scales? Twist: This neuron has extreme properties that helps it work ~300x times faster than neurons in the hippocampus Summary 🧵to follow
2309
Reposted by Scott Pluta
Ann Clemens @annmclemens.bsky.social · 17/04/2025
My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour. Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org
15143
Reposted by Scott Pluta
Takaki Komiyama @takakikomiyama.bsky.social · 18/04/2025
Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...
science.org
Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learning
Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...
220463
Reposted by Scott Pluta
Pierre Apostolides @pfapostolides.bsky.social · 17/04/2025
(Plz repost) I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, neural circuit dynamics, and/or hearing rehabilitation. pierre.apostolides @ umich .edu Tyvm
12618
Reposted by Scott Pluta
Eshaan Iyer @eshaaniyer.bsky.social · 15/04/2025
Thrilled to see this part of my PhD work with @rcbagot.bsky.social now out in @natcomms.nature.com! (1/14) www.nature.com/articles/s41...
nature.com
Reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs cooperatively modulates engagement - Nature Communications
Neural circuit mechanisms underlying integrating information about reward across time are not fully understood. Here, the authors show that common outcome-integration signals from the medial...
54519
Reposted by Scott Pluta
Earl K. Miller @earlkmiller.bsky.social · 10/04/2025
Neurons just keep mixing their selectivity. Whisking and locomotion are jointly represented in superior colliculus neurons journals.plos.org/plosbiology/... #neuroscience
journals.plos.org
Whisking and locomotion are jointly represented in superior colliculus neurons
To navigate the world, the brain needs to have internal models of self-motion, for example of whisker movement in mice. This study shows how neurons in the midbrain superior colliculus encode internal...
25612
Scott Pluta @scottrpluta.bsky.social · 08/04/2025
Basically, there are only downsides to cutting funding for science. Who would have thought...
000
Scott Pluta @scottrpluta.bsky.social · 08/04/2025
It brings me real satisfaction to see this long overdue piece in the whisker system puzzle come to fruition. Suma Chinta's implementation of the LNP model was incredible. After seeing this data for 3+ years now, it still amazes me how well SC neurons predict movements - past, present, and future! 🐭
012
Scott Pluta @scottrpluta.bsky.social · 02/04/2025
It's funny how the "motor cortex" has really good sensory responses. We see the same thing in vibrissae M1. Sensory processing has largely been ignored in the arm movement literature. Big oversight, IMO. Cutaneous vs. proprioceptive responses are tough to disentangle, though. So, I get it.
010
Scott Pluta @scottrpluta.bsky.social · 01/04/2025
The dendritic calcium events in S1 are definitely different than what we've observed in somatic firing rates. I can only speculate why. @kjayant.bsky.social has this data in prep. Perhaps the value-based map in the dendrites has a subtle effect we did not observe. Perhaps it is cell-type specific.
120
Scott Pluta @scottrpluta.bsky.social · 01/04/2025
Yes, we were surprised to discover that the sensory map in superior colliculus (SC) is biased by stimulus value, while the map in cortex maintained a faithful representation of receptor space. Bias in the SC map emerged only when the sensory associations had opposite values. Check out the paper!
1133
Scott Pluta @scottrpluta.bsky.social · 01/04/2025
Across the neural hierarchy, sensory maps are thought to transition from a faithful representation of receptor space to a map weighted by learned associations. Where does this transformation occur? In our latest paper, we explore a value-based spatial transformation between cortex and midbrain.
journals.plos.org
052
Scott Pluta @scottrpluta.bsky.social · 23/03/2025
Close them. Don't look back.
010
Reposted by Scott Pluta
Jeremy Berg @jeremymberg.bsky.social · 06/03/2025
Compelling pushback from @jmgrohneuro.bsky.social and the Board of Scientific Counselors at the National Institute on Mental Health (NIMH) regarding termination of tenure-track investigators driven by DOGE. 1/2
191054351
Reposted by Scott Pluta
Jacquelyn Gill @jacquelyngill.bsky.social · 04/03/2025
This is an attempt to criminalize free speech and suppress dissent. If we don’t take a strong stand against this, it’s the end of our democracy, and not just higher education. Universities are the trial balloon, but it doesn’t end here. Next, it will be employers, cities and towns, and individuals.
A tweet by @realDonaldTrump that reads: All Federal Funding will STOP for any College, School, or University that allows illegal protests. Agitators will be imprisoned/or permanently sent back to the country from which they came. American students will be permanently expelled or, depending on the crime, arrested. NO MASKS! Thank you for your attention to this matter.
20458132
Reposted by Scott Pluta
Jordan Hamm @jordanhamm.bsky.social · 27/02/2025
I'm hiring a full-time research technician to work in my lab at Nathan Kline. Benefits included! Some lab experience preferred... experience with mouse surgeries a huge plus. If you live in NYC, there are two daily shuttles that take ≈20 min from upper manhattan. nki.applicantpro.com/jobs/3663631
nki.applicantpro.com
Research Technician I (Emotional Brain Institute) (210-2025-06) - Orangeburg, NY
JOB DESCRIPTION: The Emotional Brain Institute (EBI) is a multidisciplinary institute aimed at addressing fundamental questions in neuroscience and neuropsychiatry. We seek to hire a research technici...
033
Reposted by Scott Pluta
Vinny Costa @vincentcostaphd.bsky.social · 27/02/2025
The NIH intramural program is a unparalleled in both its ability to do bleeding edge science and train the next generation of scientists. Not renewing Title 42 employees is hellacious. www.science.org/content/arti...
science.org
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
16527
Scott Pluta @scottrpluta.bsky.social · 26/02/2025
Yes, still waiting for that subcellular-scale imaging of membrane voltage (with kilohertz sampling) across hundreds or thousands of neurons in an awake-behaving animal. Oh, and up to 1 mm deep, too, please. Then comes all the analysis...
020
Reposted by Scott Pluta
John Tuthill @tuthill.bsky.social · 26/02/2025
Just learned that the Sensorimotor Neuroscience (SMN) study section is postponed indefinitely. Over 100 proposals to understand and treat sensorimotor diseases that will not be evaluated or funded. Thousands of hours wasted by writers and reviewers. All due to the Republican block on NIH operation.
02112
Reposted by Scott Pluta
Adam Hantman @adamhantman.bsky.social · 26/02/2025
Such bad news.
022