iiinova — where your digital self keeps evolving

Reposted by Jordan Hamm

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/08/2026

A dominant frontoparietal beta oscillatory brain state in the days after psilocybin and 5-MeO-DMT www.biorxiv.org/content/10.64898/20…

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Jordan Hamm @jordanhamm.bsky.social · 02/04/2026

Huge congrats to my grad student, Dr. Anna Rader Groves, who successfully defended her disseratation last week! I consider myself lucky to have mentored Anna over the past 5 years.

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Jordan Hamm @jordanhamm.bsky.social · 29/01/2026

Excited to share our preprint! Impressive effort from grad student Anna Rader Groves and co-author @cgalli-io.bsky.social, in collaboration with Melanie Grubisha and Robert Sweet (PITT). @grubisha

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Jordan Hamm @jordanhamm.bsky.social · 08/01/2026

Excited to share our preprint! We show that primary visual cortex is modulated by global predictability. This effect depended on higher level brain region (area ACa), and better explained classic oddball paradigms better than “local” context effects (i.e., recent stimulus history). 1/3

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Reposted by Jordan Hamm

Adam Hockley @adhockley.bsky.social · 07/01/2026

Our new preprint is out! We show that deviance detection in auditory cortex conveys the theorised comparison of internal prediction to sensory input. Our data confirm this key assumtion that links theoretical models of sensory processing to experimental data. www.biorxiv.org/content/10.6...

biorxiv.org

Cortical deviance detection represents a canonical difference signal

Context modulates neural processing of sensory stimuli. Neural responses are suppressed to stimuli that are typical in their context and augmented to stimuli that deviate from their context. The latte...

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Reposted by Jordan Hamm

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 19/08/2025

Visuomotor mismatch EEG responses in occipital cortex of freely moving human subjects www.biorxiv.org/content/10.1101/202…

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Reposted by Jordan Hamm

Sofiya Hupalo @sofiyahupalo.bsky.social · 12/08/2025

Just learned that my @acnporg.bsky.social panel was accepted! With my colleagues Zoë Hughes, @jordanhamm.bsky.social, Bryan Baxter & Patricio O'Donnell, our #ACNP2026 panel will highlight cross-species approaches using functional brain-based biomarkers to address translational gaps in psychiatry

media.tenor.com

a group of people jumping off a cliff into a body of water with a caption that says colnah.cy

Alt: people jumping off a cliff into a body of water

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Jordan Hamm @jordanhamm.bsky.social · 05/08/2025

First lab outing since the move to NYC.... feeling so lucky to have such a talented and fun group! with Lital Rachmany, @adhockley.bsky.social, me, Molly Hornick, Fumiyasu Imai, and @cgalli-io.bsky.social

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Jordan Hamm @jordanhamm.bsky.social · 21/05/2025

I’m delighted to congratulate Dr. Connor Gallimore for successfully defending his dissertation, “Patterns of laminar engagement during visual mismatch processing”. I consider myself lucky that Connor joined my lab in 2019. His CV, though impressive on its own, doesn’t even scratch the surface.

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Jordan Hamm @jordanhamm.bsky.social · 13/04/2025

Beautiful views and stimulating science discussion this week at University of Zurich/ETH Zurich with Wolfger von der Berhens, Fatih Yanık and many others. Honored to share my work with such a world class group!

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Jordan Hamm @jordanhamm.bsky.social · 27/02/2025

I'm hiring a full-time research technician to work in my lab at Nathan Kline. Benefits included! Some lab experience preferred... experience with mouse surgeries a huge plus. If you live in NYC, there are two daily shuttles that take ≈20 min from upper manhattan. nki.applicantpro.com/jobs/3663631

nki.applicantpro.com

Research Technician I (Emotional Brain Institute) (210-2025-06) - Orangeburg, NY

JOB DESCRIPTION: The Emotional Brain Institute (EBI) is a multidisciplinary institute aimed at addressing fundamental questions in neuroscience and neuropsychiatry. We seek to hire a research technici...

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Jordan Hamm @jordanhamm.bsky.social · 16/02/2025

New results from study of cortical thickness in 1211 psychosis cases and 734 controls demonstrates that "visual cortex is among the most profoundly affected brain regions", with effect sizes larger than prefrontal regions. www.medrxiv.org/content/10.1...

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Reposted by Jordan Hamm

Rafael Yuste @rafaelyuste.bsky.social · 10/02/2025

Press release of our new article in Neuron: How Does the Brain Differentiate New Stimuli From Old Ones? | Columbia News news.columbia.edu/news/how-doe...

news.columbia.edu

How Does the Brain Differentiate New Stimuli From Old Ones?

A study sheds light on how networks in the brain detect new information, offering insight into disorders like schizophrenia.

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Jordan Hamm @jordanhamm.bsky.social · 10/02/2025

Our new paper is out in Neuron! We characterize auditory prediction errors across primary and secondary regions, to simple and complex stimuli. Deviance detection (and context) are distinct from basic adaptation -- even in a simple oddball paradigm. 1/2 www.sciencedirect.com/science/arti...

sciencedirect.com

Slow cortical dynamics generate context processing and novelty detection

The cortex amplifies responses to novel stimuli while suppressing redundant ones. Novelty detection is necessary to efficiently process sensory inform…

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Reposted by Jordan Hamm

Phil Corlett @philcorlett.bsky.social · 29/01/2025

Comment on our recent paper challenging the link between MMN dysfunction and positive symptoms: www.sciencedirect.com/science/arti... Thanks @mattnour.bsky.social I may have missed it but cognitive map dysfunction is also unrelated to positive symptoms so far?

sciencedirect.com

If Mismatch Negativity Is the Answer, What Is the Question? On the Nature of Predictive Coding Abnormalities in Psychosis

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Jordan Hamm @jordanhamm.bsky.social · 22/01/2025

www.nature.com/articles/s41... Lots to unpack in this Nat Neuro paper on schiz genetics (ctx-wide GABA, amygdala, no DA?) One thing: in terms of exc neurons, a vis-ctx specific cluster (133) and a ctx-wide cluster (123) is as implicated (if not, more) than the most prominent PFC cluster (404).

nature.com

Mapping the cellular etiology of schizophrenia and complex brain phenotypes - Nature Neuroscience

Duncan and colleagues link specific human brain cell types to schizophrenia and other complex brain phenotypes, providing mechanistic insights and a cellular taxonomy for psychiatric disorders.

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Reposted by Jordan Hamm

Daniel Trubman @danieltrubman.bsky.social · 19/01/2025

One of the disappointing trends for urban college neighborhoods over the last few years is the introduction and maintenance of restrictions on access in and thru formerly open walkways. So it's great to see efforts to protect these public easements. www.nydailynews.com/2025/01/15/a...

nydailynews.com

Admission denied: Columbia must reopen its gates

This is an open letter to Columbia University Interim President Katrina Armstrong. Dear President Armstrong,

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Reposted by Jordan Hamm

Rose Bagot @rcbagot.bsky.social · 09/01/2025

New lab preprint ! There is a lot of excitement about the therapeutic potential of psilocybin but what is the mechanism? A beautiful body of work from @alexkwan.bsky.social shows that PFC plasticity is important. But how does this unfold and in which cell types? www.biorxiv.org/content/10.1...

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Jordan Hamm @jordanhamm.bsky.social · 17/12/2024

We're all parts of institutions, and we're all vexed by seemingly pointless obstacles and bureaucracy at one point. Chesterton's fence provides a great lesson -- "Do not remove a fence until you know why it was constructed in the first place" #neuroskyence fs.blog/chestertons-...

fs.blog

Chesterton’s Fence: A Lesson in Thinking

A core component of making great decisions is understanding previous decisions. If we don’t understand how we got “here,” we run the risk of making things much worse.

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Reposted by Jordan Hamm

Rebecca Solnit @rebeccasolnit.bsky.social · 05/12/2024

Here is a somber truth of creative life. If it goes well, people will begin to ask you for things. Each of those things, no matter how kind or flattering or genuine or even beneficial to your own career and finances as well as someone else's, will pull you from your true purpose.

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Jordan Hamm @jordanhamm.bsky.social · 27/11/2024

Our spotlight article in Trends in Neurosciences is out! We contextualize the recent findings by Furutachi, Hofer et al in the broader literature on V1 deviance detection and prediction error www.sciencedirect.com/science/arti...

sciencedirect.com

An expanding repertoire of circuit mechanisms for visual prediction errors

Cortical responses to stimuli vary dependingon context and expectation. Adding insight into this process, Furutachi et al. recently demonstrated that …

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