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Pierre Apostolides

@pfapostolides.bsky.social
112 followers 108 following 138 posts

Cellular physiologist LARPing as a systems neuroscientist. Enthusiastic about new age music, fine scale model building (mostly styrene, sometimes computational), and non-linear processes in biological networks. www.apostolideslab.org

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Reposted by Pierre Apostolides
Adema Ribic @ademaribic.bsky.social · 23/09/2026
My blueskyless and twitterless friend Elise Savier has organized a conference for systems neuro of subcortical circuits: broad range of topics, great speakers and I am jealous of the location. Please repost and consider attending
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Reposted by Pierre Apostolides
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 26/08/2026
Developmental NMDA receptor signaling regulates cerebellar unipolar brush cell number and dampens excitability www.biorxiv.org/content/10.64898/20…
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Reposted by Pierre Apostolides
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/08/2026
Representations of Pitch and Timbre of Instrument Sounds in the Inferior Colliculus www.biorxiv.org/content/10.64898/20…
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Pierre Apostolides @pfapostolides.bsky.social · 10/08/2026
One of my favorite “biologically accurate fictional details” is in Sade’s “No Ordinary Love” video where the Mermaid (played by Adu herself) sits at the bar and adds salt to her glass of water.
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Pierre Apostolides @pfapostolides.bsky.social · 05/08/2026
Congratulations to Grienberger Lab!!! Worth a read!
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Reposted by Pierre Apostolides
Lavinia Sheets @olybinewski.bsky.social · 02/08/2026
My dept. posted this on the other site and it’s not getting any ♥️, so I’m posting it here 🦋 Excited to work with lead PI Artur Indzhykulian (Harvard/MEE) and co-I Marcos Sotomayor (University of Chicago) on this important study & grateful to the Ushers Syndrome Society @washumedicine.bsky.social
Photo of Lavinia Sheets in a zebrafish facility, backlit and holding a tank of zebrafish, with a note that she has been awarded a collaborative grant from the Usher Syndrome Society to test Mini-Cdh23 gene therapy for Usher’s Syndrome Type 1D in the zebrafish model.
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Pierre Apostolides @pfapostolides.bsky.social · 30/07/2026
Seen at MBL.
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Reposted by Pierre Apostolides
kameron-clayton.bsky.social @kameron-clayton.bsky.social · 29/07/2026
We're hiring a research technicians to work a new NIH-funded project on the emergence of hearing after cochlear gene therapy in congenital deafness. Come join us! massgeneralbrigham.wd1.myworkdayjobs.com/MGBExternal/...
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Reposted by Pierre Apostolides
Rune W. Berg @runewberg.bsky.social · 28/07/2026
New paper: Spinal circuitry modeled for locomotion using spatial transcriptomics and cell-type projections. Local excitation, long-range inhibition, and a longitudinal skew—an asymmetric "Mexican hat"—give rhythm, rotational dynamics, and gait, with no pacemakers. www.nature.com/articles/s41...
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Pierre Apostolides @pfapostolides.bsky.social · 15/07/2026
Wait, so the modern world cares about supervised learning? Turns out the cerebellum field was onto something all these years
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Pierre Apostolides @pfapostolides.bsky.social · 15/07/2026
Jianing’s got a good point here. We should also think about the ethological validity of experimenter vs subject trial initiation. Are we modeling flashcard performance or world-exploration?
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Pierre Apostolides @pfapostolides.bsky.social · 11/06/2026
We’ve all wanted to know the answer to this question for years. Congrats Aaron for figuring it out
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Pierre Apostolides @pfapostolides.bsky.social · 11/06/2026
Yep.
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Pierre Apostolides @pfapostolides.bsky.social · 10/06/2026
Who was the A&R rep who decided Spasmolytic would be the single from Skinny Puppy’s seminal album Too Dark Park? Clearly this was the wrong call, Grave Wisdom is the superior song off the album. Ready to (amicably and non physically) fight anyone who says otherwise
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Pierre Apostolides @pfapostolides.bsky.social · 03/06/2026
LLMs are like any other machine, they’re either a benefit or a hazard. If they’re a benefit, that’s not my problem.
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Pierre Apostolides @pfapostolides.bsky.social · 21/05/2026
Congrats Manoj!
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Pierre Apostolides @pfapostolides.bsky.social · 16/05/2026
This is such an elegantly simple solution to ROI-specific photostim.
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Reposted by Pierre Apostolides
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 12/05/2026
Presynaptic GABAA Receptors Mediate Ethanol-Induced Suppression at a Central Auditory Synapse www.biorxiv.org/content/10.64898/20…
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Pierre Apostolides @pfapostolides.bsky.social · 05/05/2026
This seems pretty cool. Congrats Meeks lab
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Reposted by Pierre Apostolides
Hearing Health Foundation @hearinghealthfn.bsky.social · 21/04/2026
"Researchers with Oregon Health & Science University [Laurence Trussell, former grantee] and Anhui University in China found in a mouse model that elevated levels of the neurotransmitter serotonin in the brain also resulted in elevated behavioral symptoms of tinnitus." news.ohsu.edu/2026/04/20/r...
news.ohsu.edu
Research links tinnitus with serotonin
Neurotransmitter known for relieving depression could have opposite effect on tinnitus.
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Reposted by Pierre Apostolides
Maria Geffen @geffenlab.bsky.social · 14/04/2026
Tune it at 1 pm EDT to EARS early career panel! pennmedicine.zoom.us/j/96672201477
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Pierre Apostolides @pfapostolides.bsky.social · 07/04/2026
Congrats Ruth Anne!!
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Reposted by Pierre Apostolides
Jimmy Dooley @jimmycdooley.bsky.social · 06/04/2026
New paper (with lots of cute animal videos!) Ever watch your dog "run" while asleep and wonder what’s going on in their brain? In Current Bio we suggest that those twitches aren't just leaky dreams—they’re a vital maintenance system for the most precise movements www.cell.com/current-biol...
cell.com
REM-sleep twitching in adults and the maintenance of specialized sensorimotor systems
Blumberg et al. present video evidence of twitching during adult sleep in a diverse sample of animals. Adult twitching appears to selectively involve appendages used for active sensing, mirroring thei...
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Reposted by Pierre Apostolides
Robert Kelchen @robertkelchen.com · 27/03/2026
Staff and administrators saw one final year of pay raises exceeding inflation this year, but that won't happen again for a while. Tenure-line faculty have had raises below inflation every year for the past decade. Tenure and promotion boosts are often modest (3-10%), and only happen twice.
cupahr.org
Workforce Pay Increases - CUPA-HR
This is the public version of this data. CUPA-HR is the most comprehensive, accurate, and up-to-date source of higher education workforce salary data, collected separately for administrators, faculty,...
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Pierre Apostolides @pfapostolides.bsky.social · 23/03/2026
David showed me some of these data about a year ago and all I could respond was “how does it feel to be right?” A milestone in the quest to find synapse-level explanations for brain function and behavior.
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Reposted by Pierre Apostolides
Aaron Wong @aaronbwong.bsky.social · 20/03/2026
🎻✨ Excited to share my journey from music to auditory research at "Beer, Brain, and Arts!" during Brain Awareness Week. Join us tomorrow at the @hetnatuurhistrdam.bsky.social, or a lab tour at Erasmus MC @erasmusmc.bsky.social ! 🔗 www.brain-awareness-week-euc.nl #BrainAwarenessWeek #Neuroscience
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Reposted by Pierre Apostolides
Ross Williamson @rswilliamson.bsky.social · 20/03/2026
Excited to share some new work from my lab, where we rigorously characterize differences between L5 and L6b extratelencephalic neurons in the auditory cortex!
biorxiv.org
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Pierre Apostolides @pfapostolides.bsky.social · 07/03/2026
Philly has a Rocky statue, NOLA’s got one of Ignatius Reilly. Only fair Delta City honor a notorious fictional denizen as well. Very happy this statue finally found a home after years of deliberation.
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Reposted by Pierre Apostolides
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 03/03/2026
NMDA receptor-dependent presynaptic homeostatic plasticity? www.biorxiv.org/content/10.64898/20…
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Pierre Apostolides @pfapostolides.bsky.social · 26/02/2026
Thank you NIDCD for supporting our work on learning-related plasticity in mammalian sound localization circuits.
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Stephen David @stephenvdavid.bsky.social · 24/02/2026
Call it #ExplainableAI or just making sense of complexity. We establish a direct link between DNNs fit to #AuditoryCortex and more intuitive subspace models from the 2000s. Congrats @jeremewingert.bsky.social @satyaparida.bsky.social & Sam Norman-Haignere! #NeuroAI #SensoryNeuroscience rdcu.be/e5gLY
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Pierre Apostolides @pfapostolides.bsky.social · 23/02/2026
Reminds me of Philip K Dick’s UBIK
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Reposted by Pierre Apostolides
Christine Grienberger @cgrienberger.bsky.social · 17/02/2026
🚀 New preprint from the lab! Our first foray into the subiculum uses in vivo whole-cell recordings to show that dendritic plateaus are a prominent, learning-dependent signaling mode of subicular neurons. Feedback is welcome! www.biorxiv.org/content/10.6...
biorxiv.org
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Pierre Apostolides @pfapostolides.bsky.social · 12/02/2026
Big if true. Anyone know if human learning curves are also (mostly) trial count independent? www.nature.com/articles/s41...
nature.com
Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience
Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...
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Reposted by Pierre Apostolides
Symbolic Sound Kyma @symbolicsound.com · 07/02/2026
Excited to share results from our new PNAS paper. We studied PNIPAM—a shape-shifting polymer that collapses from an extended coil to a compact globule near body temperature — making it a prime candidate for drug delivery systems and soft robotics.
pnas.org
Water-mediated hydrogen bonds and local side-chain interactions in the cooperative collapse and expansion of PNIPAM oligomers | PNAS
Poly(N-isopropylacrylamide) (PNIPAM), a thermoresponsive homopolymer, is a well-established model for investigating coil-to-globule transitions. He...
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Pierre Apostolides @pfapostolides.bsky.social · 07/02/2026
Ok, ok, hear me out. What happens when you make the human-owl hybrids wear prism goggles?!
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Pierre Apostolides @pfapostolides.bsky.social · 04/02/2026
Lotta cool 😎 people on this
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Reposted by Pierre Apostolides
Yunlu Zhu @yunluzhu.bsky.social · 03/02/2026
Thrilled to share that I’ll be starting my lab at the Kresge Hearing Research Institute, Dept of Otolaryngology University of Michigan in May! We study how the brain turns gravity signals into stable movement → zhulab.fish (yup, proudly a #zebrafish lab🐟) If you're interested, get in touch! #newPI
zhulab.fish
Yunlu Zhu Lab [University of Michigan]
Systems neuroscience lab at the University of Michigan studying brain's gravity code for balance, with a focus on neurons and glia in vestibular function and dysfunction 🐟
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Reposted by Pierre Apostolides
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 02/02/2026
Presynaptic control of top-down signaling in neocortical layer 1 www.biorxiv.org/content/10.64898/20…
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Reposted by Pierre Apostolides
Prof Sarah-Jayne Blakemore @sjblakemore.bsky.social · 01/02/2026
In Cambridge in the 1970s, my dad, Colin Blakemore, worked and lectured on sensitive periods of sensory development. In my Cambridge undergrad lectures on this topic, I show a clip from one of his TV shows, which describes sensitive periods for sound categorisation, and features Prof Janet Werker:
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Pierre Apostolides @pfapostolides.bsky.social · 20/01/2026
Finally, Gary Larson’s “cow tools” comic is cited in a scientific paper. Job well done
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Pierre Apostolides @pfapostolides.bsky.social · 16/01/2026
Another classic for the textbooks from the Marty lab
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Pierre Apostolides @pfapostolides.bsky.social · 12/01/2026
Coolest kids in Santa Clara County
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Pierre Apostolides @pfapostolides.bsky.social · 12/01/2026
Listened to the single this afternoon, it rules. Excited for the full release.
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Pierre Apostolides @pfapostolides.bsky.social · 30/12/2025
Can’t wait to do an olivocochlear project myself. but until then I’m pretty satisfied reading the great work others are doing on the topic.
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Pierre Apostolides @pfapostolides.bsky.social · 28/12/2025
I love this approach of looking at the same ensembles across a variety of behavioral tasks. Requires careful experimenters though. Great work Travis and team.
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Pierre Apostolides @pfapostolides.bsky.social · 21/12/2025
Axons. They do things they don’t just axe
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Pierre Apostolides @pfapostolides.bsky.social · 19/12/2025
Probably the most important declassification since project blue book.
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Pierre Apostolides @pfapostolides.bsky.social · 17/12/2025
I’m going to be the “old man yells at cloud” meme right now but this issue is a particular nuisance in modern restaurants and public indoor spaces. Ya can’t hear a thing in there these days.
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Pierre Apostolides @pfapostolides.bsky.social · 11/12/2025
Btw, I still have open positions available for post-docs. Esp if you’re interested in applying modern dimensionality reduction approaches to in vivo Ca2+ imaging or ephys datasets. Please get in touch pierre.apostolides@umich.edu
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