iiinova — where your digital self keeps evolving

Jason Bini, PhD @sciencedrbini.bsky.social · 03/06/2026

First time headed to ADA! Start your Saturday AM early the right way and come see me present about Advances in Pancreas Imaging during the symposium on New Ways to Measure Pancreas Form and Function with Prof John Kaddis and Prof Alvin C Powers.

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Jason Bini, PhD @sciencedrbini.bsky.social · 02/06/2026

Quick poster session before I jet off.

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Jason Bini, PhD @sciencedrbini.bsky.social · 29/05/2026

Off to LA! For Some ☀️ and science 🧪! Let's meet up!

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Jason Bini, PhD @sciencedrbini.bsky.social · 05/02/2026

Looking to recruit a postdoc for a June 1 or later start date. Details below. Familiarity/experience in PET imaging and quantification is most desired.

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Francesca Mandino @francimandi.bsky.social · 31/10/2025

Talking about spooky stuff…try to do awake mouse fMRI. Oh, you want it spookier? Try to add simultaneous Ca2+ imaging. Now, do it all again, longitudinally…. So proud to finally have this out!!! 🐭 🧠 🧲 Go read…if you dare!! 👻 www.biorxiv.org/content/10.1...

biorxiv.org

Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice

Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...

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Jason Bini, PhD @sciencedrbini.bsky.social · 30/10/2025

Not entirely convinced reviewers 1 and 2 even read our manuscript...

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Jason Bini, PhD @sciencedrbini.bsky.social · 28/10/2025

Imagine my excitement reading this title only to find out it's not *that* IPA 🍺😂

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Jason Bini, PhD @sciencedrbini.bsky.social · 16/10/2025

Hey that's us! First official Bini lab preprint 🎉

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Peter Zeidman @corticalpete.bsky.social · 16/09/2025

A birthday is a good time to reflect! To mark SPM @ 30, this month's issue of Cerebral Cortex features deeply insightful commentaries on neuroimaging analysis from Ed Bullmore, Peter Bandettini, Peter Fox, Pedro Valdes-Sosa, Klaas Enno Stephan, Viktor Jirsa, et al [1/2] academic.oup.com/cercor/issue

academic.oup.com

Issues | Cerebral Cortex | Oxford Academic

Publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus.

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Jason Bini, PhD @sciencedrbini.bsky.social · 09/09/2025

If you haven't seen it yet, check out our article highlighted Up Front as an editors pick in the @DiabetologiaJnl September issue!

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Science Magazine @science.org · 31/07/2025

The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.

scim.ag

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency

Republicans on spending committee push back against proposed reorganization and overhead cuts

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STAT @statnews.com · 29/07/2025

NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half. www.statnews.com/2025/07/29/n...

statnews.com

NIH is shrinking the number of research projects it funds due to a new Trump policy

NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.

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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 29/07/2025

"Concerns are rising that President Donald Trump’s administration is finding new ways to shrink the U.S. biomedical research enterprise [right now]" Great article from @jocelynkaiser.bsky.social at @science.org 🧪

science.org

Odds of winning NIH grants plummet as new funding policy and spending delays bite

Funding multiyear grants up front will sharply cut number of investigators receiving awards

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Rosa Lafer-Sousa @rosalafersousa.bsky.social · 29/07/2025

🚨 Required reading for every scientist, academic admin, and member of Congress 🚨 The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪

scienceandfreedomalliance.substack.com

A Quiet Policy Shift That Could Devastate American Science

Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university

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Jason Bini, PhD @sciencedrbini.bsky.social · 28/07/2025

Very excited for this review to be out! A dive into PET/MRS techniques for measuring brain glucose concentrations and cerebral metabolic rate of glucose in the context of diabetes and obesity. #neuroimaging #obesity #diabetes #metabolism #neuroendocrinology link.springer.com/article/10.1...

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Max Kozlov @maxkozlov.bsky.social · 02/06/2025

DOGE is now reviewing every NIH grant that goes out, I reported last week. That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports. Gift link: wapo.st/3HhnPSt

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@LaBonneLaB @labonnelab.bsky.social · 03/06/2025

Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post. www.washingtonpost.com/opinions/202...

washingtonpost.com

Opinion | Universities and the government: Which needs the other more?

From public health to high-tech innovation, universities are the workhorses of national progress.

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Perry Bacon @perrybaconjr.bsky.social · 29/05/2025

The university endowment tax in the Republican/Trump economic plan sets a dangerous precedent of the government slapping excessive taxes on institutions it disagrees with ideologically. It also will cause cuts in jobs, financial aid and research funding. wapo.st/3HiYtDv

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Andrew Hardaway @andrewhardaway.bsky.social · 29/05/2025

The "Make America Health Again" Report has the word "obesity" in it 51 times and yet the primary US institute that researches the impact and new treatments for obesity (NIDDK) would be sure to have their budget cut under the current spending bill or the White House recs (40% cut to the NIH budget).

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Jason Bini, PhD @sciencedrbini.bsky.social · 29/05/2025

It's not a fully formed thought but someone needs to connect the collapse of universities/colleges all across the country with the collapse of the sports (scholarships) industrial complex. I would guess a HUGE economy is kids sports in hopes of playing big time college sports.

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Drug Monkey @drugmonkey.bsky.social · 28/05/2025

Could be huge. Especially for those terminated in the anti-DEI purge. "...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award" grants.nih.gov/grants/guide...

grants.nih.gov

NOT-OD-25-115: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibility for Mentored Career Development Award When an Award Ended Ear...

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibi...

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Alexandra Witze @alexwitze.bsky.social · 21/05/2025

Sworn testimony of NIH officials and internal emails reveal just how much DOGE is calling the shots in killing peer-reviewed biomedical research grants. More bombshell reporting from @maxkozlov.bsky.social in @nature.com:

nature.com

NIH killed grants on orders from Elon Musk’s DOGE

Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13/05/2025

"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants. Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."

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Joey Fishkin @fishkin.bsky.social · 27/04/2025

University leaders need to understand: they are holding INCREDIBLY good cards. It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.

Graphic of Washington Post poll from April 18-22, 2025, showing "Majorities of Americans oppose various Trump proposals"

highlighting two lines in particular:
"Increasing the Federal Government's role in how private universities operate" - 28 percent support, 70 percent oppose
"Reducing federal funding for medical research" - 21 percent support, 77 percent oppose

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Jason Bini, PhD @sciencedrbini.bsky.social · 24/04/2025

Opthalmology Chic. Keeping that eye health in check!

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Jason Bini, PhD @sciencedrbini.bsky.social · 23/04/2025

Thanks to The Grey Matter Project, Sreya and Prof Sara Schaefer for the invite and organizing! Really fun to talk to the HS students who are the next generation of Drs and researchers about neuroendocrinology. medicine.yale.edu/neurology/ed...

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Alice Callahan @alicecallahan.bsky.social · 16/04/2025

My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...

nytimes.com

Leading Nutrition Scientist Departs N.I.H., Citing Censorship (Gift Article)

Kevin Hall said his work on ultraprocessed foods has been “hobbled” under the Trump administration. Scientists have been raising such concerns for months.

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Kevin Hall @kevinh-phd.bsky.social · 16/04/2025

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.

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Jason Bini, PhD @sciencedrbini.bsky.social · 04/04/2025

If you have patients or folks you know who have recently been diagnosed with stage 1 or 2 Type 1 Diabetes in the Northeast. Have them contact us! Recruiting for longitudinal PET/MRI studies!

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Lahari Basu @laharibasu.bsky.social · 26/03/2025

I am excited and proud to share that the full version of my first research article is now available at Diabetes 🥳 Our manuscript shows the effects of cisplatin, a commonly used chemotherapeutic agent, on pancreatic islet function in mice. diabetesjournals.org/diabetes/art...

diabetesjournals.org

Cisplatin Exposure Dysregulates Insulin Secretion in Male and Female Mice

Cancer survivors have an increased risk of developing type 2 diabetes compared with the general population. Patients treated with cisplatin, a common chemo

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Reposted by Jason Bini, PhD

Eric Topol @erictopol.bsky.social · 26/03/2025

How a zero calorie sugar substitute, sucralose, can increase appetite by activating the hypothalamus @natmetabolism.bsky.social nature.com/articles/s42...

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Jason Bini, PhD @sciencedrbini.bsky.social · 21/03/2025

Learned a lot from this thread! And Michaelis-Menton enzyme kinetics is the basis of all kinetic modeling in PET imaging!

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Nature Reviews Endocrinology @natrevendo.nature.com · 17/03/2025

In our April issue: @liisagalea.bsky.social and colleagues outline how the effects of steroid hormones on hippocampal neuroplasticity across the adult lifespan differ between the sexes, highlighting the importance of considering sex and steroid hormones in biomedical research rdcu.be/edRF3

Figure showing differential effects of steroid hormones on adult hippocampal neurogenesis in males and females across the lifespan.

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Mike Ginn @shutupmikeginn.bsky.social · 08/03/2025

its amazing how chatgpt knows everything about subjects I know nothing about, but is wrong like 40% of the time in things im an expert on. not going to think about this any further

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Joe Allen @joeallenjoe.bsky.social · 12/03/2025

In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide. news.harvard.edu/gazette/stor...

news.harvard.edu

NIH funding delivers exponential economic returns — Harvard Gazette

Report finds all 50 states reap gains in patient health, job creation, research resources, business development.

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Helen Czerski @helenczerski.bsky.social · 12/03/2025

It's hard to say this, but science (& research more generally) is just being **stopped** in the US right now. This is just one university, losing nearly a billion dollars in project funding pretty much overnight. That's people's jobs & the research that could save lives. www.wsj.com/health/healt...

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The Wall Street Journal @wsj.com · 11/03/2025

The Trump administration has terminated $800 million in grants to Johns Hopkins University, spurring the nation’s top spender on research and development to plan layoffs and cancel health projects

wsj.com

Johns Hopkins Plans Staff Layoffs After $800 Million Grant Cuts

Local and international health research efforts are already winding down as the university braces for even more potential cuts.

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Jamie Daw @jamiedaw.bsky.social · 11/03/2025

I received one of the 232 NIH grant "terminations" sent to scientists at Columbia last night. My research focuses on improving maternal and child health in the US. Also affected: ongoing clinical trials, research training programs, and research centers that aim to improve the health of Americans.

gothamist.com

Hundreds of research grants at Columbia canceled following Trump edict, administrator says

The National Institutes of Health is terminating 232 grants for scientific research at Columbia University Irving Medical Center, according to an email an administrator sent to faculty.

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Tom Pepinsky @tompepinsky.com · 08/03/2025

The public really needs to understand this. Every university system in the world rests on public funding, there has never been an alternative model at any time in history. We have universities for literally the same reason that we have roads and armies.

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Stina Börchers, PhD @stinaborchers.bsky.social · 08/03/2025

🧠🍽️ #Amylin acts in the central amygdala (CeA) to regulate feeding & motivated behavior We show that CeA amylin signaling is critical for appetite suppression, macronutrient selection & body weight control. Disrupting this pathway leads to hyperphagia & weight gain. #Neuroskyence 🧪 #ObesityResearch

cell.com

From the pancreas to the amygdala: New brain area critical for ingestive and motivated behavior control exerted by amylin

Molecular biology; Neuroscience

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Jason Bini, PhD @sciencedrbini.bsky.social · 03/03/2025

Update... after NIH website chaos(?) over the weekend. Looks like there are a slew of new 01-R01s (91 NoAs since Feb 17) which is now about 50% of the number from the same 2 wk period in 2024 (186). Across many institutes it seems.

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Jason Bini, PhD @sciencedrbini.bsky.social · 02/03/2025

Med School Administration still acting like this is all a passing concern... Told to apply for internal bridge funding if you think you'll be in trouble in the near future. Unless those bridges are 5-10 years long, and start now, 100% soft money folks are absolutely SOL.

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Surprised Face Guy @surprisedface.bsky.social · 27/02/2025

AOL warned us of the dangers of logging on. It would play for us the screams of the damned. But we didn’t listen. We didn’t listen.

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