iiinova — where your digital self keeps evolving

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David Schoppik @schoppik.com · 20/01/2026

House Appropriations minibus bill funding NIH is out now. - $400M increase - Multiyear funding of new awards capped at 2025 levels. - No line item for BRAIN Initiative text here: docs.house.gov/billsthiswee... Screenshots from Dem summary and Sec 240 (multiyear funding text).

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Asha Rangappa @asharangappa.bsky.social · 01/10/2025

It would be great to find out if Patel is still sending new agents to the Holocaust Museum as part of their training. We went in the first week and after seeing the museum had a discussion about complicity and law enforcement that was led by someone from the ADL. This was started in 2001 by Freeh.

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Constantin Ahlmann-Eltze @const-ae.bsky.social · 04/08/2025

Our paper benchmarking foundation models for perturbation effect prediction is finally published 🎉🥳🎉 www.nature.com/articles/s41... We show that none of the available* models outperform simple linear baselines. Since the original preprint, we added more methods, metrics, and prettier figures! 🧵

Beeswarm plot of the prediction error across different methods of double perturbations showing that all methods (scGPT, scFoundation, UCE, scBERT, Geneformer, GEARS, and CPA) perform worse than the additive baseline.

Line plot of the true positive rate against the false discovery proportion showing that none of the methods is better at finding non additive interactions than simply predicting no change.

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Katie Mack @astrokatie.com · 19/06/2025

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

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Gabi Serrato Marks @gserratomarks.bsky.social · 20/05/2025

NIH moved up the expiration date for some funding opportunities, effectively *canceling* the next application date without removing it from the standard table. I can't even imagine how many people are still prepping these grants. 👀 List of impacted opportunities: grants.nih.gov/grants/guide...

Screenshot of NIMH BRAINS funding opportunity. The expiration date is now before the next application due date.

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Neil deGrasse Tyson @neildegrassetyson.com · 19/05/2025

If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.

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Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025

Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025

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Jack Iwashyna @iwashyna.bsky.social · 17/05/2025

Co-sign (as a cis het white man whose father went to college.) The broad classes of science and scholars lumped under “DEI” has been some of the most productive and insightful we have seen in medicine with huge benefits throughout the system

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Ran Blekhman @blekhman.bsky.social · 17/05/2025

"NIH funding is gone, so you should pivot to private foundations for funding" Meanwhile, private foundations:

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Kaia Mattioli @kaiamattioli.bsky.social · 28/04/2025

i'm just a senior postdoc, standing in front of a career that i have worked really hard for, asking higher education in the united states to not completely implode in front of my eyes before i even get a chance to say the words 'my lab studies'

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Rogan Grant @rogangrant.bsky.social · 23/04/2025

Low-level processing of spatial transcriptomics data has me re-learning geometry and linear algebra and I am not terribly happy about it

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Mehdi Hasan @mehdirhasan.bsky.social · 22/04/2025

Absolutely brutal and hilarious takedown of Bill Maher from the one and only Larry David.

nytimes.com

Opinion | Larry David: My Dinner With Adolf

When a private meeting goes unexpectedly.

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The Onion @theonion.com · 17/04/2025

Nation Can’t Believe It On Harvard’s Side

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Azure @spicycurry.bsky.social · 15/04/2025

Very thankful to Haverford for standing up, considering their only superdonor is a prominent member of the administration. Do better, UW.

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Sergio Cruz-León @sergiocruzleon.bsky.social · 11/04/2025

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

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Tristan Snell @tristansnell.bsky.social · 10/04/2025

Forcing people to pay $130 for a passport in order to vote is just a Jim Crow poll tax by another name. It is blatantly unconstitutional.

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Jordan Meier @doc-jlmeier.bsky.social · 10/04/2025

Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost. www.training.nih.gov/research-tra...

training.nih.gov

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Aaron Rupar @atrupar.com · 09/04/2025

Rep. Steven Horsford to Greer: "So the trade representative hasn't spoken to the POTUS about a global reordering of trade, but yet he announced it on a tweet? WTF! Who is in charge? It looks like your boss just pulled the rug out from under you. There is no strategy ... is this market manipulation?"

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southpaw @nycsouthpaw.bsky.social · 09/04/2025

If the agent of an embittered KGB officer somehow won the US presidency and entered into the office bent on destroying the USA in its national influence, network of alliances, and the American people’s quality of life, what would he be doing differently?

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Rogan Grant @rogangrant.bsky.social · 09/04/2025

Trumpism has turned out to be DEI for people with immense privilege who failed entirely on their own merits and punishment for those with a modicum of success

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Brendan Nyhan @brendannyhan.bsky.social · 09/04/2025

We hang together or we hang separately. Could not be clearer what is happening and how universities must respond.

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Rogan Grant @rogangrant.bsky.social · 03/04/2025

Is it possible to short an index fund?

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Schmidt Science Fellows @schmidtfellows.bsky.social · 02/04/2025

We are excited to announce our 2025 Schmidt Science Fellows! 32 early career researchers, nominated by the world’s leading research universities, who will take an interdisciplinary approach to advancing discovery schmidtsciencefellows.org/news/2025-fe...

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Nature @nature.com · 27/03/2025

The massive changes in US research brought about by the new administration of President Donald Trump are causing many scientists in the country to rethink their lives and careers go.nature.com/41OhAgK

go.nature.com

75% of US scientists who answered Nature poll consider leaving

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

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Scott Shapiro @scottjshapiro.bsky.social · 24/03/2025

White House says no one will be fired over the Signal scandal because no one involved was trying to cure cancer.

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Rogan Grant @rogangrant.bsky.social · 19/03/2025

I would love for someone to explain to me what this has to do with scientific research or the funding that supports it

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Denis Wirtz @deniswirtz.bsky.social · 17/03/2025

ICYMI, NIH will be asking soon for each NIH-funded researcher to justify every draw they make (often several times a week) on their grants and every NIH officer and their boss will have to justify their agreeing on these draws. This is the death of US biomedical research by a thousand cuts

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Karen Tani @kmtani.bsky.social · 15/03/2025

Columbia Law School has perhaps the strongest public law faculty in the country. This is what they think of the recent Title VI demand letter sent to their university: balkin.blogspot.com/2025/03/a-ti...

balkin.blogspot.com

Balkinization: A Title VI Demand Letter That Itself Violates Title VI (and the Constitution)

A group blog on constitutional law, theory, and politics

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Geoff Swanson @gtswanson.bsky.social · 15/03/2025

My Senator. What a tool. Absolutely failed to rise to the moment and then puts out the bullshit justification. Illinois we can do better.

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Jeremy Berg @jeremymberg.bsky.social · 07/03/2025

Great crowd in Pittsburgh Standing Up for Science. Thanks to all of the other great speakers sharing their stories!

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Rogan Grant @rogangrant.bsky.social · 03/02/2025

Is ERA/NCBI down for anyone else?

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Michael Baym @baym.lol · 28/01/2025

If you’re at a European institution and are looking to poach American scientists, this would be a very good week to do it

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Science Magazine @science.org · 27/01/2025

The National Institutes of Health has clarified the restrictions on travel, purchasing, and meetings that President Donald Trump’s new administration imposed on NIH staff last week, easing some concerns about measures that set off chaos within the agency. scim.ag/3WD2g3j

scim.ag

NIH memo addresses ‘confusion’ about restrictions imposed by Trump, easing some concerns

Memo from acting director to staff allows some purchasing, and suggests travel and study sections could soon resume

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Celia Ford @celiaford.bsky.social · 23/01/2025

Hi, Vox reporter here: If you've had a study section, NIH travel, or other NIH-related meeting cancelled (or not), raise your hand! Reply or DM me, and repost for visibility if you're able. #academicsky @drugmonkey.bsky.social

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Carl T. Bergstrom @carlbergstrom.com · 22/01/2025

Communications shutdown. Travel ban. Canceled study sections. Now a hiring freeze? Shutting down the NIH indefinitely without stated cause is literally an act of sabotage. Left: yesterday. Right: today.

Jan 21 2025: 27 job openings listed at NIH.

Jan 22 2025: There are no postings at this time.

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Josh Barocas, MD ⭕️ @jabarocas.bsky.social · 23/01/2025

Why should the public care about the freeze on the NIH? Aside from the need for scientific pursuits to make our society better… -For every dollar we invest in NIH research, there is a $2.5 return. -Research dollars help fund universities that employ non-academics. (1/)

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@LaBonneLaB @labonnelab.bsky.social · 22/01/2025

Here it comes #science folks: Trump has instructed federal health agencies to pause all external communications, such as health advisories, weekly scientific reports, updates to websites and social media posts including officials at the National Institutes of Health

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Rogan Grant @rogangrant.bsky.social · 21/01/2025

Hard to even make these things up at this point

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Jennifer X. Pumpkins 🎃 @jenyetagain.bsky.social · 16/01/2025

it mattered a lot less to me that lynch was weird than that he was kind. the fact that here's a guy who wrestled with these deep philosophical and existential questions in his art and instead of being haughty or cynical his conclusion was that people are good, he wanted to be good.

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Rogan Grant @rogangrant.bsky.social · 16/01/2025

We lost one of the great visual artists of our time

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Louis Peitzman @louispeitzman.bsky.social · 16/01/2025

OK but this is actually untenable. There aren’t enough real people on here to balance things out. I’ve gotten hundreds of these in the last day, and it makes it sort of feel like this whole app is bots.

Screenshot of follows from bots, mostly named Naomi and Nora.

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Rogan Grant @rogangrant.bsky.social · 15/01/2025

Xenon's effects on the brain are fascinating

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Rogan Grant @rogangrant.bsky.social · 15/01/2025

I was briefly considering attending my 10-year college reunion until...

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Hani Goodarzi @genophoria.bsky.social · 13/01/2025

A month ago we @vevotherapeutics.bsky.social announced that we have generated the largest single-cell perturbation atlas in history, Tahoe-100M. Today, we announce that we will fully open-source Tahoe-100M in Feb, as part of a collaboration with NVidia health to train cell state models.

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