Dibsy et al. show that proteasomal degradation of the Aurora B kinase is required for cytokinetic abscission in human cells. Aurora B degradation reduces the phosphorylation of its substrate, CHMP4C, ...

Cytokinesis finalizes cell division by physically separating the daughter cells. After furrow ingression, the intercellular bridge (ICB) connecting th…

The changes announced by a major UK science funder are putting scientists — and the future of research — in a difficult position.

In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…

Neurons and muscles must maintain structural contact despite mechanical strain. Ermanoska et al. identify a presynaptic actomyosin core at Drosophila neuro

Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.

SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...