On-the-fly conditioning of pretrained protein generative models guides protein generation toward specific properties.

On-the-fly conditioning of pretrained protein generative models guides protein generation toward specific properties.

Adenine base editors (ABEs) are CRISPR effectors that introduce A-T to G-C transitions in the genome using a nucleotide deaminase fused to a Cas protein. ABEs have been evolved to have very high editi...

Variant mapping of sorghum promoters identifies CRISPR-accessible mutations that upregulate gene expression.

TnpB endonucleases are engineered for improved genome editing.

Leveraging RNA-targeting dCas13d enables selective interference with phage protein translation and facilitates measurement of phage gene fitness at a transcriptome-wide scale.