Reposted by Peter MaceSergey Ovchinnikov @sokrypton.org · 14/09/2026Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr) 727698
Reposted by Peter MaceJemma Geoghegan @jemmageoghegan.bsky.social · 12/05/2026New paper out today with @josephguhlin.bsky.social where we did penguin GWAS to better understand disease risk and found that these penguins represent three deep evolutionary lineages www.nature.com/articles/s41...nature.comPopulation genomics of yellow-eyed penguins uncovers subspecies divergence and candidate genes linked to respiratory distress syndrome - Nature Ecology & EvolutionWhole-genome data from 249 yellow-eyed penguins (hoiho) identify three lineages with high geographical and genomic divergence, and candidate gene variants associated with differential susceptibility t... 23417
Peter Mace @petermace.bsky.social · 08/04/2026Massive Congrats to @pseudokinase.bsky.social for being named an Honorary Fellow of the Royal Society of NZ! Been great collaborating and enjoying niche 90s live music over the years. Also well done @peterkdearden.bsky.social and the new NZ-based fellows! www.royalsociety.org.nz/news/latest-...royalsociety.org.nzLatest cohort of Ngā Ahurei Fellows announcedTwenty-one new Ngā Ahurei Fellows have been elected to the Academy of the Royal Society Te Apārangi, including one Honorary Fellow. Fellowship recognises researchers, scholars, and innovators through... 080
Reposted by Peter MaceCell - a Cell Press journal @cp-cell.bsky.social · 21/03/2026Now online! The E3-ome gene-centric compendium reveals the human E3 ligase landscapedlvr.itThe E3-ome gene-centric compendium reveals the human E3 ligase landscapeThe E3-ome defines the human repertoire of ubiquitin E3 ligases, creating a unified resource that maps their diversity across the ubiquitin and ubiquitin-like systems. By consolidating fragmented knowledge, this framework provides a foundation for studying ubiquitin signaling and accelerating discovery. 01811
Reposted by Peter MacePeter Fineran @peterfineran.bsky.social · 04/03/2026New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments. 55350
Reposted by Peter Maceiubmb.bsky.social @iubmb.bsky.social · 23/01/2026Our biannual newsletter is out 📬 Insights, updates, and what’s ahead—read the latest edition here: bit.ly/4pY9jzA 022
Reposted by Peter MacePeter Mabbitt @petermabbitt.bsky.social · 29/11/2025We’ve made some new tools to manipulate N-recognins. Check them out in our preprint. www.biorxiv.org/content/10.1... 01813
Peter Mace @petermace.bsky.social · 12/11/2025Honour to have our Plenary from Nobel Laureate Sir Richard Roberts at our NZSBMB Conference 2025 010
Reposted by Peter MaceDr. Natalia Riobo-Del Galdo @thehedgehoglab.bsky.social · 10/11/2025We have a fully funded studentship to start your PhD in October 2026! Work with me, Elton Zeqiraj and Joe Cockburn to find new ways to treat diseases with high levels of Hedgehog signalling. Fantastic training in cell and structural biology, genomic screening and biochemistry at the Uni of Leeds!findaphd.comStopping GLI transcription factors in their tracks: identifying regulators of proteolysis as therapeutic targets. at University of Leeds on FindAPhD.comPhD Project - Stopping GLI transcription factors in their tracks: identifying regulators of proteolysis as therapeutic targets. at University of Leeds, listed on FindAPhD.com 174
Reposted by Peter MaceOtago Biochemistry @otagobiochemist.bsky.social · 07/11/2025Just confirming what we already knew: Otago Biochemist Associate Professor Lynette Brownfield is an awesome postgrad supervisor! This week awarded the Division of Health Sciences Supervisor of the year. Here she is with her group of young scientists enjoying a well-earned break amongst the rhodies. 021
Reposted by Peter MaceGuillaume Thibault @gthibault.bsky.social · 05/11/2025Ready for a transformative research journey? 🚀 Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships. Hear from our students and faculty in the video below 👇 youtu.be/JeZHiXu3fgEyoutu.beNTU College of Science PhD opportunitiesYouTube video by College of Science NTU 143
Peter Mace @petermace.bsky.social · 18/10/2025Is the alphafold database performing really poorly, and Uniprot alphafold links broken for everyone, or just me? I've tried clearing my cache, but any tips @ebi.embl.org? 121
Reposted by Peter MaceBrett Collins @brettcollins.bsky.social · 12/10/2025Open Group Leader Positions at the IMB, UQ. Interested in joining us in sunny Queensland?uq.wd3.myworkdayjobs.comGroup Leader - Institute for Molecular Bioscience (IMB)Institute for Molecular Bioscience Join a university ranked in the world’s top 50 Australia’s #1 research institute Based at St Lucia Campus About UQ What started as Queensland's first university in 1... 01920
Peter Mace @petermace.bsky.social · 08/10/2025Excellent course content for my scientific writing class! 020
Reposted by Peter MaceEdward T Eng @edwardteng.bsky.social · 04/10/2025Muyuan Chen has turned structural biology into an immersive experience with his new video game Meowtabolism, now available on Steam. Try the demo here: store.steampowered.com/app/4045010/... Give Muyuan feedback: steamcommunity.com/app/4045010 #ScienceGaming #StructuralBiology #CryoEM #STEMOutreachstore.steampowered.comMeowtabolism - Examining Feline Behavior within Unicellular Algae on SteamExplore the interior of an algal cell on your four paws. Built with experimental data and populated with actual protein structures, Meowtabolism offers a glimpse of the vast world inside the basic fun... 15426
Reposted by Peter MaceJosh Hardy @joshuamhardy.bsky.social · 28/09/2025I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.09.24.678028 #proteindesign 28731
Peter Mace @petermace.bsky.social · 15/09/2025We're hiring! Come join us as a Lecture/Senior Lecturer in the fantastic supportive Biochemistry Department at the University of Otago. Dunedin is a super-liveable city, which just happens to have some of the best access to nature (and biking) in Aotearoa...... otago.taleo.net/careersectio... 131
Reposted by Peter MaceBen Williamson @benpatrickwill.bsky.social · 07/09/2025Peer reviewers are exhausted. It's common to spend *months* inviting reviewers, getting refusals, inviting more, maybe 12 or more, then 2 agree but 1 doesn't complete, so you go again. That's why your paper is in limbo. I'm very sorry, it's awful, but it's also an untenable academic labour issue. 11664108
Reposted by Peter MaceMikhail Spivakov @mspivakov.bsky.social · 19/07/2025Translational research is digging for gold. Basic research is learning where and what to dig. The more funding is diverted to translation, the more we deplete the research ecosystem, driving the supplies of "gold" - immediately translatable findings and innovations - to unsustainably low levels. 37027
Reposted by Peter MaceOtago Biochemistry @otagobiochemist.bsky.social · 26/08/2025Biochemistry Special Seminar Wed 27 Aug 1pm Rm BIG13 Distinguished Professor Natarajan Kannan, University of Georgia Evolution of regulation in signaling systems: From ancient cores to modern complexity 041
Peter Mace @petermace.bsky.social · 21/08/2025Vinnie Tagliabracci kicking off the final morning of #iubmbkinases, post conference dinner crowd still strong (with coffee....) 000
Reposted by Peter MaceJames Murphy @pseudokinase.bsky.social · 20/08/2025Onward into metabolism. Kicking off the pm session with Grace Gong (LMB) and John Burke (UVic) #iubmbKinases @iubmb.bsky.social We thank @biochemsoc.bsky.social #BiochemJ for their support of this session. The weather couldn’t even lure us away! 064
Peter Mace @petermace.bsky.social · 20/08/2025Welcoming Grace Gong back to NZ to kick off afternoon number 3, lipid kinases at #iubmbkinases 022
Reposted by Peter MaceJames Murphy @pseudokinase.bsky.social · 20/08/2025Day 3 of #iubmbKinases @iubmb.bsky.social and many of us sprung up to take this photo through the conference room window - even during talks. Queenstown turning on a stunner of a day, matched only by some terrific science 072
Reposted by Peter MaceJames Murphy @pseudokinase.bsky.social · 18/08/2025Flying start to the #iubmbkinases meeting in beautiful Queenstown, NZ. Jubilee Award from IUBMB to Kevan Shokat yesterday, and a kinase masterclass from Susan Taylor this morning 0145
Reposted by Peter MaceTroy Baisden @troybaisden.bsky.social · 15/08/2025Robust debate in Parliament yesterday, with questions from Scott Willis to Shane Reti MP about cuts, job losses and whether reprioritisation will yield clarity or any benefits. The answers aren't reassuring but it is good to see this getting attention. youtu.be/Vam6UmnvtyYyoutu.beRSIT in Parliament – Oral Q5 14 Aug 2025YouTube video by New Zealand Association of Scientists 156
Reposted by Peter MaceTigist Tamir @phosphotig.bsky.social · 15/08/2025This! journals.biologists.com/jcs/article/...journals.biologists.comWhy would anyone want to be a scientist?It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently... 0114
Peter Mace @petermace.bsky.social · 02/08/2025Four weeks left for abstract submission and early-bird registration for the NZ Society for Biochemistry and Molecular Biology annual meeting!! Adele Williamson and William Kelton are putting together an amazing program including outstanding plenary speakers! www.nzsbmb.org/conference-2025-rotorua 112
Peter Mace @petermace.bsky.social · 29/07/2025Excited to see this work led by Cameron Reddington and Annabel Walsh out in @febsj.bsky.social — ASXL proteins share a PHD domain that is not a PHD domain, evolved to bind an MBD domain that is not an MBD domain! febs.onlinelibrary.wiley.com/doi/10.1111/...febs.onlinelibrary.wiley.comFEBS PressA plant homeodomain (PHD) at the C terminus of additional sex combs-like (ASXL) proteins is recurrently truncated in disease. In the current study, the ASXL PHD was shown not to bind histone modifica... 032
Reposted by Peter MaceAmro Hussien @amrohussien.bsky.social · 25/07/2025For every €1 invested in Horizon Europe programme, Europe is expected to get as much as €11 in GDP return Source: www.innovationnewsnetwork.com/horizon-euro...innovationnewsnetwork.comHorizon Europe delivers €11 GDP return for every €1 investedLearn how Horizon Europe is driving innovation and growth across the EU, with up to €11 in GDP returns and sixfold societal benefits by 2045. 084
Peter Mace @petermace.bsky.social · 10/07/2025A fantastic oral program is now in place, but you can still register and submit an abstract for the IUBMB Focussed Meeting on (Pseudo)kinases in signal transduction! Outstanding setting, with ample chances to exchange ideas with the top kinase minds in the world! www.ivvy.com.au/event/IUBMB25/ 110
Peter Mace @petermace.bsky.social · 20/06/2025It's June 20 in New Zealand, which means it's the last day to have your abstract considered for oral presentations at the IUBMB Focussed Meeting on kinases and pseudokinases! 122
Peter Mace @petermace.bsky.social · 17/06/2025Check out the view today from the venue—scoping for the IUBMB Focussed meeting on (pseudo)kinases! Abstracts and early bird registrations closes this week! www.ivvy.com.au/event/IUBMB25/ @pseudokinase.bsky.social @iubmb.bsky.social 262
Reposted by Peter MaceBen Eltham @beneltham.bsky.social · 14/06/2025Excellent article by Rock Morton in the Saturday Paper this morning, on consultants Nous. These guys are so endemic in university managements I ended up writing a whole paper about them. They're basically vampires www.thesaturdaypaper.com.au/news/educati...thesaturdaypaper.com.au‘Mind-boggling stupidity’: The consultancy that captured universitiesNous Group has slowly taken over the university sector, filling VCs’ offices with ex-staff and buying ‘incredibly sensitive’ data that is sold back for benchmarking. 1426699
Peter Mace @petermace.bsky.social · 12/06/2025Only one week left to submit your abstract and register at early bird rates for the IUBMB Focussed Meeting - (pseudo)kinases in signal transduction. Sign up and register by June 20!! Join @pseudokinase.bsky.social Natalia Jura, and a who's who of kinase research! www.ivvy.com.au/event/IUBMB25/ 132
Reposted by Peter MaceLaura Edgington-Mitchell @lauraem-lab.bsky.social · 22/05/2025The 13th General Meeting of the International Proteolysis Society will be held in Búsios, Brazil Oct 26-30, 2025. Training workshops will be held at the Instituto Oswaldo Cruz Oct 23-23. Register now! Links below. 1/3 178
Peter Mace @petermace.bsky.social · 23/05/2025With less than a month to submit abstracts for the @iubmb.bsky.social Focussed Meeting on (pseudo)Kinases in stunning Queenstown, we are delighted to announce travel scholarships for selected ECRs thanks to @biologists.bsky.social and the Maurice and Phyllis Trust! www.ivvy.com.au/event/IUBMB25/ 156
Reposted by Peter MaceGregory Kohn @kohngregory.bsky.social · 12/05/2025In an age of triumphant managerialism, we must remember that giving researchers support, autonomy, and freedom results in miraculous things. Another point is that the government required AT&T to invest in basic research to avoid being treated as a monopoly. 1517.substack.com/p/why-bell-l...1517.substack.comWhy Bell Labs Worked.Or, how MBA culture killed Bell Labs 28939
Reposted by Peter MaceUniversity of Otago - Ōtākou Whakaihu Waka @universityofotago.bsky.social · 07/05/2025Two Otago academics, Dr Olivia Harrison and Professor Jemma Geoghegan, have been awarded Prime Minister's Science Prizes for their outstanding work on managing viruses and managing anxiety. Ngā mihi nui! 👏 Read more here:otago.ac.nzPrime Minister’s prizes awarded to two Otago academicsWork on managing anxiety and managing viruses has resulted in two Otago academics receiving Prime Minister’s Science Prizes. 1347
Reposted by Peter Maceiubmb.bsky.social @iubmb.bsky.social · 08/05/2025Congratulations to Professor Kevan Shokat from the University of California, San Francisco, 🇺🇸, recipient of the IUBMB Jubilee Award Lecture. His award lecture will be presented at the IUBMB Focused meeting on "The Emerging roles of (pseudo)kinases in signal transduction". @asbmb.bsky.social 031
Reposted by Peter MaceWorld Bollard Association™️ @worldbollardassoc.bsky.social · 27/04/2025For the first time in history, we can proudly show you a DOUBLE German bollarding. This has NEVER been seen before so congratulations to us. #WorldBollardAssociation 12065781046
Reposted by Peter Maceiubmb.bsky.social @iubmb.bsky.social · 24/04/2025📢Searching for REVIEWS EDITORS for IUBMB Life, BioFactors, and Biotechnology and Applied Biochemistry. ‼️Apply by May 31, 2025 022
Reposted by Peter Maceiubmb.bsky.social @iubmb.bsky.social · 24/04/2025📢Searching for IUBMB Publications Committee members ‼️Apply by May 31, 2025 002
Reposted by Peter MaceNature Biotechnology @natbiotech.nature.com · 23/04/2025By combining high-throughput protein engineering with machine learning, bespoke SpCas9 enzymes are identified that outperform evolution-based and engineered nucleases and base editors in human cells. www.nature.com/articles/s41... #NBTHighlightnature.comCustom CRISPR—Cas9 PAM variants via scalable engineering and machine learning - NatureNature - Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning 02710
Reposted by Peter MaceIECB Bordeaux @iecb.bsky.social · 14/04/2025We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!! 02022
Reposted by Peter MaceMolecular Cell @cp-molcell.bsky.social · 23/03/2025Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactionsdlvr.itPredictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactionsSchmid and Walter train a classifier that discerns functionally relevant structure predictions in proteome-wide protein-protein interaction (PPI) screens using AlphaFold-Multimer, and they use this confidence metric to curate a database of 40,000 predicted interactions among ∼300 genome maintenance proteins. 073
Reposted by Peter MacePablo Arantes @pabloarantes.bsky.social · 20/03/2025I’ve just updated the BioEmu notebook to include the powerful LogMD. Now, you can generate equilibrium ensembles and explore the full ensemble directly in the notebook. A huge thanks to Alexander Mathiasen for the support! 🙌 🔗 Try it on Google Colab: lnkd.in/gcuqd-fT 35117
Reposted by Peter MaceKate Michie @kmichie.bsky.social · 14/03/2025Uni of Wollongong Cryo EM job closes on Sunday people! @gokhan-tolun.bsky.social might be able to answer questions? 🧬🧶seek.com.auAssociate Research Fellow - SEEKSeeking an Associate Research Fellow to provide expert advice and support to UOW members of the ARC Training Centre for Cryo-EM of Membrane Proteins. 087
Reposted by Peter MaceKomander Lab @komanderlab.bsky.social · 13/03/2025Exciting news from the lab out today in Science - the structure of human PINK1 on a TOM-VDAC complex! @wehi-research.bsky.social 06513