Mutations that provide antibiotic resistance in bacterial pathogens often disrupt key cellular processes. The effects of these disruptions on cellular physiology are poorly understood, especially with...

Some of Otago’s mid-career researchers will benefit from a new initiative to help New Zealand make the most of emerging biotechnology discoveries.

Science is characterized by collaboration and cooperation, but also by uncertainty, competition, and inequality. While there has always been some c...

This short video uses the example of adenosine and caffeine to introduce two key concepts in pharmacology: the agonist and the antagonist. Both, adenosine, and caffeine molecules bind to adenosine receptors on the neurons. Caffeine, the antagonist, blocks the receptor, while adenosine, the agonist, produces the biological response upon binding.

Prospective genomic newborn screening in large populations with extended follow-ups are necessary to assess the impact of the inclusion of cancer genes on outcomes. Here, the authors show that newborn...

The story behind the 100-year-old discovery that continues to render Nobel Prizes.

Abstract. Many bacteriophages encode anti-CRISPR (Acr) proteins that inhibit bacterial CRISPR–Cas immune systems. Rapid acr gene expression upon phage entr

Translational Psychiatry - Lonely minds, inflamed guts: metabolic and circulating protein pathways linking social isolation and loneliness to inflammatory bowel disease

Stories of NZ science and nature from out in the field and inside the labs.

Join keynote speakers Nic Rawlence, University of Otago and Emilio Mármol Sánchez, University of Copenhagen for an exploratory workshop for researchers interested in generating and utilising historica...

Tyla Hill-Moana, a PhD student from Te Tari Matū Koiora - the Department of Biochemistry, recently had a trip of a lifetime visiting one of the most geographically isolated inhabited places on Earth, ...

University of Otago – Ōtākou Whakaihu Waka researchers have helped identify the cause of a previously unrecognised neurodevelopmental disorder.

The University of Otago's Department of Biochemistry celebrated a significant milestone last week, hosting the 50th annual Meeting of the Biochemistry Department Research Society. A longstanding tradi...

Pseudokinases are the catalytically-dead counterparts of protein kinases and, over the past 20 years, have increasingly garnered attention as crucial signaling entities—comprehensively dispelling the...

Abstract. Proteins and non-coding RNAs are functional products of the genome that are central for crucial cellular processes. With recent technological adv

Comment from Auckland University: Decades of research funding cannot be replaced by funding the commercialisation of that science

Cells capture and utilize many forms of energy to power their molecular processe

Congratulations to all who graduated from the Department of Biochemistry in August. Tino pai rawa atu!

and treasuring your exceptions