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Kate Michie

@kmichie.bsky.social
2.7K followers 956 following 1.2K posts

Interested in Structural Biology, deep learning, NextFlow, HPC, viruses, missense mutations archaea, bacteria, evolution & random quirks of nature. (Protein Cosmos feed 🧶🧬) Leads a research group & Structural biology Facility,UNSW Sydney. Opinions my own.

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Kate Michie @kmichie.bsky.social · 30/09/2026
This is deeply embarrassing. A simple run through Amber and it’s gone. That should have been obvious before they started. How is it a Nature paper? How is this big news and how does it offer anything in the way of security? #structural biology glonce.com/google-deepm...
glonce.com
Google DeepMind introduces SynthID Bio to watermark AI-designed proteins
Google DeepMind's SynthID Bio is a proof of concept for embedding an imperceptible watermark in AI-generated protein sequences and predicted 3D structures. In wet-lab tests on three targets, watermark...
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Kate Michie @kmichie.bsky.social · 18/09/2026
It’s moving insanely fast… it’s bewildering as a researcher to know where to focus right now. Still plenty of problems and limitations- the game isn’t over yet! 🤔😳#structural biology
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Kate Michie @kmichie.bsky.social · 14/09/2026
The Australian Structural Biology Computing Community is excited to host Tom Goddard from UCSF ChimeraX @chimerax.ucsf.edu on Wed 16th Sept. He will present: Predicting atomic structures with OpenFold 3 and ChimeraX—a practical look at predicting, visualising and exploring protein structures.
australian-structural-biology-computing.github.io
Welcome | Australian Structural Biology Computing
This website is a virtual meeting place and hub for all users of **computing for structural biology research in Australia**. This is a collective community effort. It can be what...
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Kate Michie @kmichie.bsky.social · 03/09/2026
ProteinDJ v3.0 is free for commercial use! Built by @joshuamhardy.bsky.social (WEHI), with contributions from @tlitfin.bsky.social and David Ladd (Audax). Commercial deps removed. New: GPU design/relaxation, BoltzGen, AF2/Boltz2 tandem and insulin-receptor binder tutorial. github.com/PapenfussLab...
Protein DJ code's logo (protein structure in white on blue) with contributors logos- WEHI (main development) and UNSW, Australian Biocommons and Audax contributions.
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Kate Michie @kmichie.bsky.social · 31/08/2026
Hey everyone- just a reminder for PhD students and early career researchers in Australia to submit their abstracts to talk at the ‘special edition’ Australian Structural Biology community talk www.biocommons.org.au/news/asbc-co...
biocommons.org.au
Invitation to present your structural biology research — Australian BioCommons
The Australian Structural Biology Computing Community is seeking Australian EMCR researchers in structural biology to share their work at a special online meeting.
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Lorne Proteins @lorneproteins.bsky.social · 25/08/2026
Every year, one T-shirt design becomes part of the conference story-worn, remembered & woven into the fabric of the conference. If yours is chosen, you'll see it come to life on delegates from across the globe as they gather in Lorne. www.lorneproteins.org/t-shirt-desi... #LorneProteins2027
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Kate Michie @kmichie.bsky.social · 13/08/2026
Great to see Julia’s work from the Burns lab out in preprint!!! Yep- even weird organisms living in Shark Bay Stromatolites get attacked by viruses. Amazing team effort- beautiful tomography by the Ghosal group and we enjoyed contributing to the protein story. 🥰🧶🧬 #archaea
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Kate Michie @kmichie.bsky.social · 12/08/2026
Super useful for so many things. Watch this space to see how the structural biology community leverages this to make workflows accessible. 🤩
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Kate Michie @kmichie.bsky.social · 10/08/2026
This is a great opportunity to present your work! Please send your abstracts to secure a spot. 🤩 Anything in computational structural biology fits the remit.
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Kate Michie @kmichie.bsky.social · 28/07/2026
Excited to hear @rolanddunbrack.bsky.social talk today ( 1 pm Sydney time) on “Structural bioinformatics and AlphaFold modeling of the human kinome and its interactions” at the Australian Structural Biology Computing community meeting. Details to join the talk:
biocommons.org.au
MEETING: Australian Structural Biology Computing Community — Australian BioCommons
Join the quarterly meeting of the Australian Structural Biology Computing community. More information
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Kate Michie @kmichie.bsky.social · 07/07/2026
Exciting work by close colleagues (and Structural Biology Facility users😉). Exciting to see it in print.
nature.com
Clocked stepping of an artificial protein walker along a DNA track - Nature Nanotechnology
A synthetic three-footed protein walker assembled from non-motor protein domains takes directional steps along a DNA track powered by Brownian ratchet motion driven by free energy transduction from mi...
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Kate Michie @kmichie.bsky.social · 07/07/2026
Ministry’s N.W.O still hits home 🤔 “You've been taken, but you don't know it yet." Not much has changed evidently.
open.spotify.com
N.W.O.
Ministry · KE*A*H** (Psalm 69) · Song · 1992
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Kate Michie @kmichie.bsky.social · 19/06/2026
Great summary and insight into Folddisco. 🧶🧬
linkedin.com
Folddisco and the Hidden Cost of Thinking at the Wrong Resolution
Data‑Rich, Insight‑Poor? —LXXIX Kim et al.’s Folddisco paper is easy to misread.
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Stephen Graham's Lab @atomicvirology.bsky.social · 09/06/2026
What do you think, should I go and try to reclaim some of my gold from abcam?
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Frances Separovic @francesbiophys.bsky.social · 05/06/2026
Protecting the role of science as a global public good in an era of geopolitical competition: The International Science Council @sciencecouncil.bsky.social calls for the protection of scientific freedom, collaboration & capacity in an era of geopolitical fragmentation council.science/statements/s...
council.science
Protecting the role of science as a global public good in an era of geopolitical competition - International Science Council
In this statement, the International Science Council calls for the protection of scientific freedom, collaboration and capacity in an era of geopolitical fragmentation, recognizing science as a global...
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Kate Michie @kmichie.bsky.social · 05/06/2026
This should give our archaeal structural protein predictions a long-needed boost. This ‘dark space’ has been a frustrating limit and I’m excited to see the impact. Great work Pedro! 🥳🧶🧬
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Kate Michie @kmichie.bsky.social · 29/05/2026
Archaea and bacteria reveal the ancient origins of another ‘eukaryotic’ complex. Membrane trafficking is old… check this out for an integrative approach showing how bioinformatics and computational structural methods marry with x-ray crystallography and cryo EM to reveal biology in all its beauty.🧶🧬
nature.com
The prokaryotic origins of the COMMD protein family involved in eukaryotic membrane trafficking - Nature Communications
COMMD proteins assemble into a heterodecameric ring in the Commander complex, which plays a role in endosomal membrane trafficking and signalling in eukaryotes. Here, Liu et al. identify COMMD-like pr...
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Kate Michie @kmichie.bsky.social · 19/05/2026
🧶🧬Tomorrow ASBC community talks:Dr Cameron Gilchrist is talking about “Multiple protein structure alignment with FoldMason” Wed 20th May Sydney, Brisbane, Canberra, Melbourne, Hobart (AEST) : 1 pm - 2 pm Adelaide (ACST): 12.30 pm - 1.30 pm Perth (AWST): 11 am - 12 pm For details of joining:
biocommons.org.au
MEETING: Australian Structural Biology Computing Community — Australian BioCommons
Join the quarterly meeting of the Australian Structural Biology Computing community. More information
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Kate Michie @kmichie.bsky.social · 07/05/2026
It’s my favourite famous human’s birthday today! Happy 100th Birthday Sir David Attenborough. How many of us went into careers in science inspired by him? When the world seem bleak he always reminds me to look at the wonder of the natural world to see something worth fighting for
theconversation.com
From fossicking for fossils to a champion for life on Earth: Sir David Attenborough at 100
David Attenborough has captured and told the stories of nature to millions of people – and inspired scientists and conservationists the world over.
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Kate Michie @kmichie.bsky.social · 09/04/2026
Our paper is out today! See this news article on it. Asgard archea have some cool proteins. If you are interested in protein evolution it’s a really exciting space. I’m lucky to be a structural biologist in the age of DL🧬🧶 @brendanburns999.bsky.social @iduggin.bsky.social @debnathghosal.bsky.social
phys.org
From Asgard to Earth: Tiny tubes may reveal the moment complex life began
Stromatolites—and their close relatives, microbial mats—could be mistaken for what seems like a bunch of old dark rocks. But instead, they are dense, layered communities of microbes. Long before compl...
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Kate Michie @kmichie.bsky.social · 07/04/2026
🧶🧬🤩 Useful! Thanks George.
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Kate Michie @kmichie.bsky.social · 03/04/2026
Hey everyone, new targets are needed now more than ever! 🧶🧬 Please consider if you have something ready to go.
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Kate Michie @kmichie.bsky.social · 01/04/2026
Big update for nf-core Proteinfold for protein people… check out v2. Great team effort! nf-co.re/proteinfold/...
nf-co.re
proteinfold: Introduction
Protein 3D structure prediction pipeline
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Kate Michie @kmichie.bsky.social · 28/03/2026
Science is at a critical juncture. More and more fundamental researchers are turning to private company jobs because they ‘pay’. More and more tech is being locked away 😳Why? Because western society has stopped valuing scientists. It’s all a bit scary. What world do we want for our kids? 🧶🧬
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Kate Michie @kmichie.bsky.social · 11/03/2026
Nice resource! Thanks for making it open access. Check your protein friends people ( and the accompanying paper in Nat. Methods). 🤩🧶🧬
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Australian BioCommons @ausbiocommons.bsky.social · 09/03/2026
Deep learning is transforming structural biology 🧬🖥️ Find out how the BioCommons-supported ASBC community is helping researchers access the software, HPC, and training needed to run predictive workflows at scale. Read more 🔗 buff.ly/azVTi2k #DeepLearning #Bioinformatics @kmichie.bsky.social
buff.ly
Accelerating deep learning in Australian structural biology research — Australian BioCommons
The Australian Structural Biology Computing community has successfully translated the 2025 national research infrastructure roadmap into a year of impactful training, useful resources and global…
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Kate Michie @kmichie.bsky.social · 06/03/2026
What’s up everyone with the division? So much noise creating wars between generations, genders, political parties, religion, cultures and nations. Humanity left the trees based on the back of being able to work together. Why is everyone so hell bent on going backwards right now?🤔 Happy Friday.
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Oliver Beckstein [he/him] @orbeckst.bsky.social · 23/02/2026
At #bps2026 : I loved the special acknowledgement of the @rcsbpdb.bsky.social and the MANY researchers who generated the experimental macromolecular structures that made it possible to build AI models for structure prediction.
Slide thanking the protein databank and all the researchers who contributed structures.
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Kate Michie @kmichie.bsky.social · 24/02/2026
🤩🧶🧬
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MACSYS @macsys.bsky.social · 18/02/2026
Meet Dr Joshua Hamey, one of our outstanding MACSYS Research Fellows. Based at our UNSW node, Josh is a molecular biologist studying how proteins are made inside cells. In this video, Josh shares insights into his research and what inspired him to join MACSYS. youtu.be/MuAfPxFXWZk?...
youtu.be
Dr Joshua Hamey - MACSYS Research Fellow
YouTube video by MACSYS
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Dr Monique Ryan @mon4kooyong.bsky.social · 19/02/2026
Already more than 5,000 Australians have joined our campaign to release more funding for medical research in the 2026 Federal Budget. If you can spare 30 seconds of your time to join our campaign, you’ll help fund life-saving cures in Australia. www.moniqueryan.com.au/medical_rese...
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Kate Michie @kmichie.bsky.social · 19/02/2026
Amazing talk today by Prof Elitza Tochaeva about the evolution of bacterial cell membrane and walls. Certainly got me thinking about bacterial and archaeal membranes. It is such a joy to see so many problems that are progressively being solved by Cryo ET. 🥰 🧬🧶 @unswbabs.bsky.social
Elitza Tochaeva presenting her work at UNSW today
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Kate Michie @kmichie.bsky.social · 19/02/2026
Super amazing work James!!! 🤩 Congratulations
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Kate Michie @kmichie.bsky.social · 16/02/2026
So nice to see this story! Jan is like a dog with a bone chasing this down. The origin of alpha/beta tubulins has been a question he won’t let go of. Great collaborative team effort and careful work. Recommended 🧬🧶
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Kate Michie @kmichie.bsky.social · 12/02/2026
Beautiful work Deb! Check out these structures? Biofilms are very interesting. 🧶🧬
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Kate Michie @kmichie.bsky.social · 11/02/2026
Dr Tom Litfin (Australian Biocommons) presented the Structural Biology Platform project and the Australian Computational Structural biology community. If you are interested and missed him you can join up here: australian-structural-biology-computing.github.io/index 🧬🧶 #lorneprotein2026
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Lorne Proteins @lorneproteins.bsky.social · 10/02/2026
Be part of Lorne Proteins history! Photo session today from 1-1:10 pm. See you there 🎉📷🤩 #lorneproteins2026
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Kate Michie @kmichie.bsky.social · 10/02/2026
Beautiful structural work on the Retromer-Rab7 complex presented by Kai-En Chen at Lorne Proteins. Also a preprint:https://www.biorxiv.org/content/10.64898/2026.01.23.701266v2 #lorneprotein2026
Slide of retromer-rab7 complex from Kevin’s presentation at Lorne Proteins 2026
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Kate Michie @kmichie.bsky.social · 08/02/2026
Just a few hours before Lorne Protein kicks off! Exciting line-up, gorgeous location. See you there. 🧬🧶
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Kate Michie @kmichie.bsky.social · 23/12/2025
This was interesting and fun to do… seems Alphafold and the like have learnt what a Leucine zipper looks like… but not really.🤔 interesting that a fully synthetic leucine zipper that couldn’t possibly assemble looked pretty probable. 🧶🧬 doi.org/10.1002/pro....
doi.org
Assessing the validity of leucine zipper constructs predicted by AlphaFold
AP-1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize...
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Kate Michie @kmichie.bsky.social · 08/12/2025
Hey structural biologists submitting PDB’s from Oceania in 2026…. Keep those structures coming via the Japanese PDB node! 🤩
Diagram describing the change in process of PBD submissions from Oceania in 2026- now going via PDBj
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Kate Michie @kmichie.bsky.social · 28/11/2025
Lots of fun delivering a talk about how to use structural predictions in biological research to Perth Protein Group yearly meeting. Perth is lovely! Wish I could have stayed longer. Great to see old friends and meet some new ones #perthproteins
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Frances Separovic @francesbiophys.bsky.social · 25/11/2025
Celebrating the scientific legacy of Shin-Ho Chung to #biophysics at the @aus-soc-biophys.bsky.social meeting #ASB2025 on the Gold Coast with excellent presentations by Toby Allen, Ben Corry, Evelyne Deplazes, Elaine Tao, Jennifer Deuis, and @ciarawallis.bsky.social
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Frances Separovic @francesbiophys.bsky.social · 25/11/2025
Hearty congratulations to Assoc. Prof. Matthew Baker @phatmattbaker.bsky.social who was awarded the MacAulay-Hope Prize for originality and innovation in #biophysics at the @aus-soc-biophys.bsky.social meeting #ASB2025 at Griffith University Gold Coast campus.
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Kate Michie @kmichie.bsky.social · 26/11/2025
🤩 I’m biased but… so sorry to have missed this.
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Kate Michie @kmichie.bsky.social · 25/11/2025
DECRAs are out! Good luck young investigators. If you are unlucky- please don't let this moment define you. #ARC
rms.arc.gov.au
Research Management System - Scheme Round Statistics for Approved Applications - Discovery Early Career Researcher Award 2026 round 1
RMS is the ARC's Research Management System, a web-based system used by eligible researchers to prepare and submit research proposals and assessments under the ARC National Competitive Grants Program ...
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Structural Phylogenetics (StrPhy) @strphy.bsky.social · 23/11/2025
Registration for #APSPM2026 closes soon. Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics. biosig.lab.uq.edu.au/strphy26 @official-smbe.bsky.social
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Alex Mason @afmason.bsky.social · 23/11/2025
The Wollongong crew have arrived in the gold coast for the #ASB2025 meeting! Just missing @lisannes.bsky.social who had presidential matters to attend to. Looking forward to the week of great science and catching up with the biophysics community in Aus!
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Frances Separovic @francesbiophys.bsky.social · 23/11/2025
Congratulations to Prof. Adelle Coster, UNSW, to whom I was honoured to present the 2025 Australian Society for Biophysics (ASB) Bob Roberston medal during ASB2025 at @griffith.edu.au. Adelle is pictured with ASB President, @lisannes.bsky.social; inaugural awardee Hans Coster; & myself 2009 medal.
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Kate Michie @kmichie.bsky.social · 23/11/2025
@costalaboratory.bsky.social Nice presentation at the Australian Biophysics conference. Amazing series of Cryo EM structures.
Alessandro starting his invited talk opening the Australian Biophysics conference on the Gold Coast
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