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Orna Issler

@ornaissler.bsky.social
421 followers 261 following 62 posts

Neuroscientist, feminist, mom Assistant Professor NYU Grossman School of Medicine Non-coding RNAs, stress, depression, sex differences, chronic pain www.theisslerlab.org

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Orna Issler @ornaissler.bsky.social · 29/09/2026
Check out this opportunity! Brilliant and dedicated PI doing very cool science!
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Leanne Holt @holtlm90.bsky.social · 29/09/2026
My lab is recruiting a postdoctoral researcher! Interested in astrocyte transcriptional regulation and addiction? We study how astrocytic transcriptional, epigenetic, and chromatin regulation contributes to substance abuse disorders. DM or email me! www.l-holt-lab.com
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Orna Issler @ornaissler.bsky.social · 16/09/2026
Turns out I have a round 5K citation on Google Scholar today! Special thanks to my supportive hubby, who checks my profile:)
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Ashley Cunningham, PhD @ashleyonthebrain.bsky.social · 24/08/2026
Very excited to share a new review with Dr. Ian Maze born out of my PhD work! 🧠🧬 We dive into how early life experiences shape the epigenetic landscape of the developing brain—and how these lasting changes may contribute to risk for affective disorders.
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Orna Issler @ornaissler.bsky.social · 13/08/2026
We're hiring! The Issler Lab (NYU Neuroscience) seeks a postdoc with expertise in hiPSC-based neuronal models to study RNA biology of mood disorders. Biofluid analysis experience (CSF, plasma) a plus. Join a collaborative team in NYC's neuroscience scene. Email: orna.issler@nyulangone.org RT
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Gal Haimovich ☣ 🧪🔬🎗 @grnfluoresceblg.bsky.social · 13/07/2026
#פידמדע ישראלים מדענים ואקדמאיים בחו״ל, נקבע המועד לעשרות כנסים בארץ: 25-26 לאוקטובר. הרשמה תיפתח בימים הקרובים: www.mind-il.org
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Megan Hagenauer @mhagenauer.bsky.social · 03/07/2026
🧠🧬 Our paper is now published in the Journal of Neurochemistry 🎉 dx.doi.org/10.1111/jnc.... During the review process, we received *exceptional guidance* from one of our reviewers, which led us to improve not only our paper, but the general Brain Data Alchemy analysis pipeline. Thank you! 🙏💛
dx.doi.org
The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta‐Analysis of Public Transcriptional Profiling Data From the Hippocampus and Cortex
Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We us....
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Alice Mosberger @alicemosberger.bsky.social · 02/07/2026
🚨Applications are now open for our S.P.i.N.E.S. Postdoc Seminar Series 2026/2027! Deadline August 15th. Find all info and link to the application here: med.nyu.edu/departments-...
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Keri Martinowich @martinowk.bsky.social · 01/07/2026
New paper out online today!! We identify two previously unrecognized transcripts at the BDNF locus, BDNF-DT and BDNF-AS-DT, that are developmentally regulated, coordinated with BDNF expression, and associated with schizophrenia risk. www.nature.com/articles/s41...
nature.com
BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus - Molecular Psychiatry
Molecular Psychiatry - BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus
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Meghan Flanigan @meghanflanigan.bsky.social · 22/06/2026
Please contact me if you are interested in my lab or any others at MUSC for your postdoc!
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Staci Bilbo @sbilbo.bsky.social · 21/06/2026
The entire NSF budget is less than what we spent in the first week of the war with Iran. The NIH accounts for a fraction of 1 percent of all federal spending. www.nytimes.com/2026/06/20/o...
nytimes.com
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
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Orna Issler @ornaissler.bsky.social · 11/06/2026
A great stretch for the issler lab! ✅ First NIH funding ✅ First conference sharing our data ✅ First departmental seminar We are on a roll!
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Orna Issler @ornaissler.bsky.social · 09/06/2026
Who knew that three letters could make me so happy! N o A
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Dr David S Anderson @dsaarchaeology.bsky.social · 27/05/2026
As an anthropologist, I endorse this message!
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Darby Saxbe @darbysaxbe.bsky.social · 20/05/2026
I have a new essay up today on how the brain changes with second-time motherhood, featuring research by the @pregnancybrainlab.bsky.social
Image of figure depicting brain changes in new mothers
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Dayu Lin @moccalin.bsky.social · 14/05/2026
Happy to share our new review on Neural Mechanisms of Social Hierarchy across Species. We discussed different routes to achieve high social status across species, from fish to humans, and the neural circuits that support each of those strategies. www.nature.com/articles/s41...
nature.com
Neural basis of social hierarchy across species
Nature Reviews Neuroscience - Structured social hierarchies, in which individuals differ in their access to resources and influence over other group members, are a characteristic of many social...
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Igor Ulitsky @igorulitsky.bsky.social · 13/05/2026
Sounds super interesting - hope we'll see more of these (lncRNAs linked by human genetics + mouse KOs to key phenotypes)! www.nature.com/articles/s41...
nature.com
An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism - Nature
PTCHD1-AS, which encodes a long non-coding RNA, is associated with the aetiology of autism spectrum disorder in humans through striatal molecular and circuit-level dysregulation.
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Laura D'Olimpio @lauradol4.bsky.social · 10/05/2026
Love this! #philsky #academicsky
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Carmen Sandi @carmensandi10.bsky.social · 08/05/2026
Hiring! Please share! Two postdoctoral researchers at EPFL, Lausanne, to join an SNSF-funded project on stress, motivation, immersive VR, physiology, multimodal sensing and translational biomarkers. Details & applications: www.fens.org/careers/job-... www.fens.org/careers/job-...
fens.org
Postdoctoral Researcher in Multimodal Human Sensing and Advanced Behavioral Data Analysis - Federation of European Neuroscience Societies
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Tallie Z Baram @talliezee.bsky.social · 06/05/2026
🧠🧪 join us here at the vibrant UC Irvine. Any career level. Great science, collaborative folks, and the weather is tolerable🤗. Please amplify @thebalelab.bsky.social @cate-cholamine.bsky.social @mayoonthebrain.bsky.social @karenswilcoxphd.bsky.social @acnporg.bsky.social @heydrdukes.bsky.social
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Melissa Cooper, PhD @melcooperphd.bsky.social · 22/04/2026
Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!
nature.com
Astrocytes connect specific brain regions through plastic networks - Nature
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.
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Dayu Lin @moccalin.bsky.social · 15/04/2026
What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan. www.nature.com/articles/s41...
nature.com
The neural mechanisms supporting the rise and fall of maternal aggression - Nature
In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically amplified by oxytocin during lactation.
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Orna Issler @ornaissler.bsky.social · 15/04/2026
Highly recommended!
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Ofer Perl @oferperl.bsky.social · 15/04/2026
We are recruiting! My lab at the University of Haifa is looking for new team members to join our research on the links between sensory perception (focus on #smell and human #olfaction) and human memory. Please help me spread the word #newPI #academia #neurostuff
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Itai Yanai @itaiyanai.bsky.social · 03/04/2026
Professors: come get trained by us in how to teach the Night Science Workshop on the creative scientific process to your students who are thirsty for this material! Our Train-the-Trainer 1day program in NYC April 24 is in partnership with the NY Academy of Sciences! night-science.org/train-the-tr...
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Orna Issler @ornaissler.bsky.social · 30/03/2026
Deadline extend till April 14th! Please RT!
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Orna Issler @ornaissler.bsky.social · 18/02/2026
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
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Orna Issler @ornaissler.bsky.social · 27/03/2026
A reminder! Do not miss out on this opportunity!
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Constantinople lab @constantinoplelab.bsky.social · 25/03/2026
Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...
nature.com
Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...
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Jeremy Berg @jeremymberg.bsky.social · 06/03/2026
Rallies tomorrow around the country! @standupforscience.bsky.social Find one near you. www.standupforscience.net www.wesa.fm/health-scien...
wesa.fm
Pittsburgh 'Stand Up for Science' rally to bring attention to impacts of immigration crackdowns
The National “Stand Up for Science” day of action returns to Pittsburgh tomorrow for the second year in a row to protest government actions and policies affecting scientific institutions, research and...
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Scott Russo @scottrussophd.bsky.social · 27/02/2026
"Cross-Organ Neuroimmunology of Behavior". Xuanming Guo and I discuss a new framework that reconceptualizes behavior as an emergent property of a distributed, brain-body neuroimmune network. lnkd.in/eihqZ_ay. @sinaiimmuno.bsky.social @sinaibrain.bsky.social
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Keri Martinowich @martinowk.bsky.social · 20/02/2026
New postdoctoral opportunity @lieberinstitute.bsky.social working w/ @tsawada1.bsky.social and our Molecular Neurogenetics team using human induced pluripotent stem cells to investigate molecular, cellular and neuroendocrine mechanisms by which impaired placental function impacts brain development
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Dr. Cate Peña @cate-cholamine.bsky.social · 18/02/2026
I am so proud to share @forrestdrogers.bsky.social’s postdoctoral magnum opus, now out in @nature.com! Forrest discovered a novel role for Agouti in the MPOA of the hypothalamus to integrate socio-environmental information to flexibly tune paternal behavior www.nature.com/articles/s41... Thread! 👇🏻
nature.com
Agouti integrates environmental cues to regulate paternal behaviour - Nature
Expression of agouti signalling protein in neurons in the medial preoptic area is increased by group housing and negatively associated with care, and overexpression of Agouti reduces care and enhances...
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Orna Issler @ornaissler.bsky.social · 18/02/2026
📣📣📣 This is a call for PhD students in neuroscience! ✅ Are you a senior PhD student in neuroscience? 🧠 ✅ Looking for career development opportunities?💼 ✅ Want to visit NYC in spring?🗽 ✅ Considering a postdoc at NYU? 🥼 ✅Apply for CoNNExINS! wp.nyu.edu/connexins/ Please RT!
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Keri Martinowich @martinowk.bsky.social · 18/02/2026
Very excited to get to share culmination of this large-scale project to understand spatial gene expression in schizophrenia. Really proud of the amazing team work here working out lots of roadblocks to deploy these spatial strategies and analysis methods at scale!
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Rachael Hokenson, PhD @neurohoke.bsky.social · 03/02/2026
Check out our new paper, investigating the role of estrogen in stress-induced memory disruptions. 🧠 online now! www.cell.com/neuron/fullt... @talliezee.bsky.social @eahellerphd.bsky.social
cell.com
Hippocampal estrogen levels, receptor types, and epigenetics contribute to sex-specific memory vulnerabilities to concurrent acute stresses
Acute concurrent stresses provoke lasting, sex-dependent memory problems. Hokenson, Rodríguez-Acevedo, et al. find that high hippocampal estrogen levels in mice generate permissive chromatin states, a...
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Caroline Menard @caromenard666.bsky.social · 03/02/2026
Out in its final form! Congratulations @sejpaton.bsky.social @jolusolo.bsky.social Alice Cadoret @adelinec.bsky.social @luisa-binder.bsky.social Béatrice Daigle @laura-mb.bsky.social Laurence Dion-Albert @katarzynaadudek.bsky.social @manonlebel5.bsky.social 🥂🧠🤓 www.nature.com/articles/s41...
nature.com
Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2 - Nature Communications
Chronic stress disrupts the brain vasculature and contributes to mood disorders, but mechanisms of resilience remain unclear. Here, the authors show that enriched environments increase astrocytic Fgf2...
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Ehud @duhe.bsky.social · 27/01/2026
Fully funded international MSc in neuroscience. Come! international.tau.ac.il/Neuroscience...
international.tau.ac.il
Neuroscience MSc
Neuroscience MSc
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Orna Issler @ornaissler.bsky.social · 16/01/2026
I am thrilled to join the ACNP community! Feels like home!
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NYULH Neuroscience @nyulhneuro.bsky.social · 11/12/2025
Undergrads, come and spend the summer with us! Applications for our Summer Research Training in Neuroscience are open now! med.nyu.edu/departments-...
med.nyu.edu
Undergraduate Summer Research Training in Neuroscience | NYU Langone Health
NYU Langone’s Neuroscience Institute offers a 10-week summer research training program in neuroscience for undergraduate students.
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NYULH Neuroscience @nyulhneuro.bsky.social · 18/11/2025
Proud of Megan Kirchgessner for being named a rising ⭐️ of neuroscience 2025 by the @thetransmitter.bsky.social #SfN25
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41... #blueprint 1/7
nature.com
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
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Megan Kirchgessner, PhD @megkirch.bsky.social · 27/10/2025
We’re so psyched for this - check out our amazing lineup of speakers!!! Spots are going fast - register today!!! 👇
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Alexandra Witze @alexwitze.bsky.social · 09/10/2025
You've probably heard how a high percentage of #Nobel laureates are immigrants. The US in particular has benefited from the influx of bright minds. @jennaahart.bsky.social ran the data for this century's Nobel prizewinners — and shows more than 30% immigrated. 🧪 www.nature.com/articles/d41...
nature.com
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
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Orna Issler @ornaissler.bsky.social · 09/10/2025
Yesterday was a good day: The honor of being called a Dorothy Lambiase Derchin Scholar in Gender-Specific Medicine A ceasefire Optimism and relief
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Orna Issler @ornaissler.bsky.social · 09/10/2025
Important negative data!
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Eric Topol @erictopol.bsky.social · 25/09/2025
A new @nature.com feature on autism with real data and facts Published today, written before the Tylenol debacle. ' Kennedy and the HHS are “going to falsely declare the cause for autism — and that that gets in the way of a great deal of progress”.' www.nature.com/articles/d41...
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Robert Reich @rbreich.bsky.social · 21/09/2025
Remember: If we allow ourselves to fall into fatalism, or wallow in disappointment, or become resigned to what is rather than what should be, we will lose the long game. The greatest enemy of positive social change is cynicism about what can be changed.
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Oded Rechavi @odedrechavi.bsky.social · 19/09/2025
Only single cell sequencing of the all these post docs will reveal why
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Nature Neuroscience @natneuro.nature.com · 22/08/2025
Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice www.nature.com/articles/s41...
nature.com
Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice - Nature Neuroscience
Activation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain mitochondrial deficits to c...
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