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Olivier Pertz

@olivierpertz.bsky.social
301 followers 315 following 33 posts

Prof at University of Bern #MAPK #Rho #optogenetics #biosensors #computer_vision skiing, rock/ice/mountain climbing when I have time

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Reposted by Olivier Pertz
Universität Bern @unibe.ch · 21/07/2026
How does a strand of #DNA about two meters long fit into a #cell nucleus when its diameter is only one-tenth the width of a hair? For more than 20 years, Peter Meister #unibern has been researching how our #genome is organized within the cell nucleus – using the #nematode C. elegans. sohub.io/14uk
Peter Meister, Institute for Cell Biology: "Two meters of DNA in a cell nucleus: That’s like trying to fit a rope stretching from Zurich to Geneva inside a basketball."
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Reposted by Olivier Pertz
Benjamin Towbin @betowbin.bsky.social · 08/04/2026
Join us at the LS2 #Theory #across #Biology chalk talk symposium! 12 June 2026 in Bern, CH. @lifesciswitzerland.bsky.social No movies that fail, no Mac to PC issues. Only the best ideas and exchange across biology from evolution and ecology to physics of life. meetings.ls2.ch/theory-acros...
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Olivier Pertz @olivierpertz.bsky.social · 08/04/2026
Cell signaling isn’t just about molecules—it’s about how cells encode information across space and time through dynamic patterns. Excited for the Dynamics and Encoding in Cell Signaling meeting in Nashville—great community, great science. 🚀 events.faseb.org/event/Dynami...
events.faseb.org
Home - Dynamics and Encoding in Cell Signaling.
Explore advances in cell communication, signaling, and imaging tech at this unique conference, bridging diverse molecular pathways and systems biology.
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Universität Bern @unibe.ch · 02/04/2026
Was passiert, wenn #Protonen mit nahezu Lichtgeschwindigkeit kollidieren? Der #Physiker Thomas Becher ist auf der Suche nach Antworten von Bern in die USA - und wieder zurückgezogen. Nun wurde er mit dem Carl-Zeiss-Humboldt-Forschungspreis ausgezeichnet: www.uniaktuell.unibe.ch/2026/der_mit_…
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Laurent Dubied @laurent-dubied.bsky.social · 02/04/2026
Spinning spheroids on 40 µm circular patterns. Recent work from @olivierpertz.bsky.social lab!
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Olivier Pertz @olivierpertz.bsky.social · 25/03/2026
I only see this now ! Thank you so much for visiting ! 2
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Reposted by Olivier Pertz
Levayer Lab @levayerr.bsky.social · 10/03/2026
Had a wonderfull time in Bern @institute fur zellbiologie 9 years after leaving the place at the end of my postdoc. Impressive system biology and quantitative approaches from @olivierpertz.bsky.social group, maybe I should go back for a 2nd postdoc...🤔
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Olivier Pertz @olivierpertz.bsky.social · 19/02/2026
So proud of Lucien
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Reposted by Olivier Pertz
Sophie G Martin @sophiemartinlab.bsky.social · 30/01/2026
The Federal Council is proposing the dissolution of the Swiss Science Council. Independent fact-based, scientific advice should be available for policy decisions.
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Journal of Cell Science @jcellsci.bsky.social · 29/01/2026
JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px @macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social. journals.biologists.com/jcs/article/...
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Lucien Hinderling @lhinderling.bsky.social · 20/01/2026
some nice circular micropatterns by @bgraedel.bsky.social and msc student moritz in @olivierpertz.bsky.social lab! stamp printed with our microfab method.
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Guillaume Jacquemet @guijacquemet.bsky.social · 15/01/2026
🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social
abo.rekrytointi.com
Laboratory Engineer (Senior), in Advanced Imaging, 1.5.2026-31.12.2028
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Fusion Conferences @fusionconf.bsky.social · 14/01/2026
@josjonkers.bsky.social @olivierpertz.bsky.social @maria-sibilia.bsky.social @lwellberg.bsky.social Please hit repost and help spread the word - Thank you!
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Olivier Pertz @olivierpertz.bsky.social · 12/01/2026
If you have 3 minutes, watch this video on the PhD work of @lhinderling.bsky.social. From ChatGPT-controlled smart microscopy to computer vision for easy image segmentation, and new insights into RAS–MAPK signaling. This earned a Faculty Prize for his thesis. www.youtube.com/watch?v=so0f...
youtube.com
Smart microscopy, computer vision, and controlling cells with light -- my PhD thesis in 3 minutes
YouTube video by Pertz Lab
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Olivier Pertz @olivierpertz.bsky.social · 29/12/2025
Thanks
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Olivier Pertz @olivierpertz.bsky.social · 21/12/2025
🔬📊 PhD (100%) – Statistics & ML for self-driving microscopy Joint PhD with David Ginsbourger (Stats) & Pertz Lab (Cell Biology). Gaussian Processes, Bayesian design, active learning on live-cell experiments. ohws.prospective.ch/public/v1/jo... #PhD #Statistics #MachineLearning #Bayesian
ohws.prospective.ch
Uni Bern: PhD Position in Statistics with a focus on Statistical Machine Learning for Self-Driving Microscopy
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epithelial mechanics fan club @epimechfc.bsky.social · 14/12/2025
Cells can sense the geometry of their environment, from tiny subcellular features to whole-tissue patterns. How can we engineer environments to systematically probe these responses? 🧵 I'm @lhinderling.bsky.social from @olivierpertz.bsky.social lab, let’s do a short tour on microfabrication!
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Olivier Pertz @olivierpertz.bsky.social · 19/11/2025
Had the Kapitein lab in Bern for a retreat about smart microscopy for optogenetics - a lot of science, walking up the hill to look at our beautiful mountains and even a Jazz concert. Outcome: new ideas, tired brains, and the beginning of something awesome. Can’t wait for round 2 in Utrecht
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Eric Topol @erictopol.bsky.social · 15/11/2025
Why do whales and elephants have much lower rates of cancer than expected? "Species with a lower cancer prevalence and mortality risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:" www.science.org/doi/10.1126/...
science.org
Coevolution of cooperative lifestyles and reduced cancer prevalence in mammals
While cooperative mammals evolve reducing cancer prevalence, oncogenes can be maintained by selection in competitive species.
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Kevin Dean @kevin-dean.bsky.social · 11/11/2025
A game changer in our hands... www.nature.com/articles/s41...
nature.com
Universal consensus 3D segmentation of cells from 2D segmented stacks - Nature Methods
u-Segment3D is a universal framework that translates and enhances 2D instance segmentations to a 3D consensus instance segmentation without training data. It performs well across diverse datasets, inc...
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Olivier Pertz @olivierpertz.bsky.social · 07/11/2025
This Wednesday @bgraedel.bsky.social defended his PhD — crowning an extraordinary scientific journey. He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales. Thanks Benjamin — a wild, inspiring ride! 🚀
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Shayan Shamipour @shamipourshayan.bsky.social · 29/10/2025
Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated image analysis pipeline! 🐟🔬📊 Huge kudos to Max Hess for this PhD milestone! 💪 @lucaspelkmans.bsky.social shorturl.at/cO0u7 Let's zoom in!
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Olivier Pertz @olivierpertz.bsky.social · 21/10/2025
Excited to join the Fusion Conference on Fibroblast Growth Factor Signalling this May in Malta 🇲🇹! I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨ #FGF #MAPK #conference www.fusion-conferences.com/conference/195
fusion-conferences.com
Fibroblast Growth Factor Signalling in Development, Health & Disease Conference | Fusion Conferences
Receptor Tyrosine Kinases (RTKs) are cell-surface receptors that, upon ligand binding, regulate cell-to-cell communication during embryonic development and in adult life. Among RTKs, the twenty-two Fi...
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Olivier Pertz @olivierpertz.bsky.social · 19/10/2025
Went to see Yayoi Kusama’s mind-bending art at the Beyeler Foundation in Basel. As a biologist, I tried to enjoy the art… but my brain kept yelling "nuclei!", “organoid!”, and “endocytosis!”. Here are some of my favorite accidental biology sightings. 🧬🎨🧫
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Lucien Hinderling @lhinderling.bsky.social · 01/10/2025
Want to get started with smart microscopy? 🧠🔬 Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati... More details in the ✨updated preprint!✨ www.biorxiv.org/content/10.1...
screenshots of some of the sample implementationsScreenshot of smartmicroscopy.github.io/implementations.html, showing an overview of collected implementation examples
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 24/09/2025
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 15/09/2025
Its raining #Ichthyos ... Hallelujah! #Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
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Olivier Pertz @olivierpertz.bsky.social · 10/09/2025
so happy to have Katie as a colleague !
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Germán Orizaola @gorizaola.bsky.social · 09/09/2025
Nice interview to Katie Peichel @currentbiology.bsky.social I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science. www.cell.com/current-biol...
cell.com
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks at the University of Bern, Switzerland.
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Olivier Pertz @olivierpertz.bsky.social · 09/09/2025
looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !
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Olivier Pertz @olivierpertz.bsky.social · 09/09/2025
⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern! 🔬 Bridge experiments + theory 📈 Tackle processes across scales 💡 Join our vibrant research community Deadline Oct 17 👉 shorturl.at/1Y1WP
shorturl.at
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) - Bern, Switzerland job with University of Bern, Institute of Cell Biology | 12840798
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) at the University of Bern, Switzerland.
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Levayer Lab @levayerr.bsky.social · 28/08/2025
Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well www.sciencedirect.com/special-issu...
sciencedirect.com
Seminars in Cell & Developmental Biology | Novel functions of programmed cell death in development: current status and future challenges | ScienceDirect.com by Elsevier
While the core regulators of programmed cell death have been relatively well characterised, our understanding of the regulation and role of programmed cell death in tissue during embryonic development...
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Systems Biology Ireland @sysbioire.bsky.social · 27/08/2025
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social ucd.ie/sbi/news/new...
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Olivier Pertz @olivierpertz.bsky.social · 22/08/2025
“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”
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Lucien Hinderling @lhinderling.bsky.social · 21/08/2025
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
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Olivier Pertz @olivierpertz.bsky.social · 22/08/2025
Congrats @lhinderling.bsky.social and team
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Lucien Hinderling @lhinderling.bsky.social · 21/08/2025
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
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Lucien Hinderling @lhinderling.bsky.social · 21/08/2025
Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:
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Lucien Hinderling @lhinderling.bsky.social · 21/08/2025
For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎
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Lucien Hinderling @lhinderling.bsky.social · 21/08/2025
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously
exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics),
and performing photomanipulation (e.g. FRAP, ablation, optogenetics).
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Lab on a Chip @labonachip.rsc.org · 06/08/2025
In the latest issue of Lab on a Chip: Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology. #OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social‬. Read now: pubs.rsc.org/en/content/a...
pubs.rsc.org
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology
The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...
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Pau Formosa-Jordan @pauformosa.bsky.social · 04/08/2025
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social‬ @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social‬ in 2023. journals.biologists.com/dev/article/...
Adapted from Fig. 1 from Kadiyala et al 2025.
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Fusion Conferences @fusionconf.bsky.social · 04/08/2025
@lwellberg.bsky.social @josjonkers.bsky.social @olivierpertz.bsky.social @juliosaezrod.bsky.social please share with your followers - thank you!
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Olivier Pertz @olivierpertz.bsky.social · 01/08/2025
Thanks for having me !
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Lucien Hinderling @lhinderling.bsky.social · 26/07/2025
first data from the new LLSM in PertzLab @olivierpertz.bsky.social! i always thought nuclei were spherical but they are pancakes???? so much more to see in 3d, but data volume produced is insane, we will have to rethink our analysis pipelines. tips welcome! here shown in @napari.org
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Silas Maniatis @manimota.bsky.social · 16/07/2025
Loved the preprint, congrats on the paper!
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Pau Guillamat @pauguillamat.bsky.social · 30/06/2025
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering
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Joachim Goedhart @joachimgoedhart.bsky.social · 27/06/2025
I'm honored - writing blogs for @the-node.bsky.social‬ has been a fabulous experience and thanks to y'all for reading and amplifying bsky.app/profile/biol...
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Olivier Pertz @olivierpertz.bsky.social · 25/06/2025
@lhinderling.bsky.social just defended his PhD with highest honors! 🌟 From code to cells, he blends computation + biology like few can. Proud to have supervised such a brilliant scientist. Watch out—Lucien’s going far! 🚀 #PhDDefense #QuantBio #CellBiology #RisingStar
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Olivier Pertz @olivierpertz.bsky.social · 25/06/2025
We’re hiring! Join us as a TT assistant professor in quantitative cell biology @UniBE. We’re looking for an experimentalist (bonus: modeling/ML/computer vision). Vibrant research, Alps nearby. 🏔️ Details: shorturl.at/PKUDU DM me with questions! #AcademicJobs #QuantBio #CellBiology
shorturl.at
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) - Bern, Switzerland job with University of Bern, Institute of Cell Biology | 12840798
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) at the University of Bern, Switzerland.
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