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Systems Biology Ireland

@sysbioire.bsky.social
42 followers 26 following 43 posts

Personalising oncology through network biology | Based in @ucddublin.bsky.social and led by Prof. Walter Kolch, SBI designs new therapeutic approaches to #cancer.

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Systems Biology Ireland @sysbioire.bsky.social · 09/10/2025
Thank you to everyone who joined us in Dublin this week for #ICSB2025! We hope all of our participants and speakers are leaving feeling inspired and motivated to continue breaking boundaries in systems biology for health. It was a great 5 days! Check out our LinkedIn & Instagram for more photos!
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Research Ireland @researchireland.ie · 08/10/2025
Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/
Siobhan Gaynor, Advanced Cancer Patient Council member and patient researcher; Prof Donal Brenan, UCD Professor of Gynae-Oncology, Consultant Gynaecological Oncologist at the Mater Hospital, and Deputy-Director of POI; Prof Walter Kolch, Director of Precision Oncology Ireland and Systems Biology Ireland (based at UCD); Dr Siobhan Roche, Director of Science for the Economy, Taighde Éireann–Research Ireland; Prof Kate Robson Brown, UCD Vice-President for Research, Innovation and Impact.
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Systems Biology Ireland @sysbioire.bsky.social · 09/10/2025
We're proud to have coordinated POI since 2019 – helping shape its design and growth into a leading, multidisciplinary initiative. Excited to kick off Stage 2 with a consortium spanning research, industry, healthcare, charity and patient sectors. #CancerInnovation #TeamScience
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Systems Biology Ireland @sysbioire.bsky.social · 03/10/2025
This is your final opportunity to be part of the world’s largest & longest-running systems biology conference series, hosted by Systems Biology Ireland in Dublin this Oct 5-9! Register now: icsb2025.com #ICSB2025 #systemsbiology #PersonalisedMedicine #Bioinformatics @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 29/09/2025
Dr. Rune Linding @humboldtuni.bsky.social is the final plenary speaker at #ICSB2025. His research focuses on big data network biology, developing powerful computational tools to understand how cells process information & to advance network medicine for diseases such as #cancer. ➡️ icsb2025.com
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Systems Biology Ireland @sysbioire.bsky.social · 24/09/2025
Prof. Kathryn Lilley from Cambridge Uni will be our Weds AM plenary speaker at #ICSB2025! A pioneer in proteomics, Lilley develops cutting-edge technologies to map the subcellular location of molecules on a global scale, providing profound insights into cellular dynamics. Register: icsb2025.com
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Systems Biology Ireland @sysbioire.bsky.social · 19/09/2025
This is the final call for poster submissions for the 24th Annual International Conference on Systems Biology! Share your work & be part of a growing community of systems biology experts. 🚨Submission deadline: Mon, Sept 22, 9 AM icsb2025.com/abstract-sub... #ICSB2025 @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 18/09/2025
Prof. Dong Yup Lee from Sungkyunkwan Uni is a plenary speaker at #ICSB2025. Lee is a leading expert in using multi-omics & computational models to guide metabolic engineering & mammalian systems biotechnology. Register today! icsb2025.com #ComputationalModelling @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 16/09/2025
Pro. Ines Thiele will be sharing her latest research in a keynote talk at #ICSB2025, Mon, Oct 6. Thiele pioneers large-scale computational models to understand how nutrition affects inherited & neurodegenerative diseases. Join us! icsb2025.com @precisiononcire.bsky.social @uniofgalway.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 16/09/2025
Prof. Sabrina Spencer is our first plenary speaker at #ICSB2025! Spencer uses advanced live-cell microscopy to uncover the non-genetic origins of cell-to-cell variability w/ a special focus on cell cycle control points, critical in #cancer. icsb2025.com @precisiononcire.bsky.social
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Cosmin Tudose @cosmintudose.bsky.social · 09/09/2025
Pleased that the 2nd part of my PhD is now available as a preprint! Here, we investigated the epigenomic and transcriptomic changes occurring upon PRC2 depletion in AML cells. biorxiv.org/content/10.1.... A thread🧵1/17
biorxiv.org
Diverse epigenomic mechanisms underpin transcriptional dysregulation in Polycomb-altered acute myeloid leukemia
Background Polycomb Repressive Complex 2 (PRC2) modulates chromatin accessibility and architecture to direct tissue-specific gene expression. PRC2 function is frequently altered in cancer by loss-of-f...
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Systems Biology Ireland @sysbioire.bsky.social · 05/09/2025
📢We've extended our poster abstract deadline to Sept 22 to accommodate anyone returning to campus who would still like to submit & attend #ICSB2025! Please spread the word! Submit your poster abstract here: icsb2025.com #personalisedmedicine #computationalmodelling @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 28/08/2025
Ready for an unforgettable evening at #ICSB2025? Join us for the official Conference Dinner on 7 Oct at Urban Brewing Dublin! 🍺Welcome drinks 6 PM 🍽️3-Course Dinner 7 PM 🎟️Tickets (purchase w/registration): icsb2025.com/registration/ @precisiononcire.bsky.social @ucddublin.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 27/08/2025
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social ucd.ie/sbi/news/new...
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Systems Biology Ireland @sysbioire.bsky.social · 21/08/2025
Get ready for the 24th Annual ICSB conference in Dublin this Oct 5-9! Check out the interactive programme below, packed with groundbreaking research & diverse session topics. Don't forget to make time for the poster sessions & fun social activities, too! #ICSB2025 icsb2025.com/programme/
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Research Ireland @researchireland.ie · 21/08/2025
Research Ireland, on behalf of @deptoffhed.bsky.social, have launched Global Talent Ireland - a new initiative to attract exceptional mid-career and established researchers from across the globe to Ireland. For more information visit: www.researchireland.ie/funding/global-talent-ireland/
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Systems Biology Ireland @sysbioire.bsky.social · 19/08/2025
David Croucher @garvaninstitute.bsky.social is speaking in the Clinical Decision Support Tools session at #ICSB2025. Hear below why you should attend this premiere event & what you will learn from David's talk in Dublin this Oct! Register ➡️ bit.ly/4450v3F @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 15/08/2025
Get ready for the 24th Annual International Conference on Systems Biology, this Oct 5 - 9 at the Dublin Royal Convention Centre! Dublin is a vibrant city rich with history & culture as well as tech & research - a perfect backdrop for #ICSB2025! Register: icsb2025.com @precisiononcire.bsky.social
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Precision Oncology Ireland @precisiononcire.bsky.social · 14/08/2025
Thrilled to join Breakthrough Cancer Research's "Cancer Revolution" launch — showcasing how research transforms patients’ lives. POI & @sysbioire.bsky.social curated a display on the synergistic power of combining lab research and computational analysis to enhance & personalise patient care
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Systems Biology Ireland @sysbioire.bsky.social · 13/08/2025
Submit your #ICSB2025 poster abstract today & open the door to global exposure, professional development, valuable feedback & new collaborations! Deadline: Sept 1 icsb2025.com #SystemsBiology #ComputationalModelling #PersonalisedMedicine #Bioinformatics #DrugDiscovery @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 12/08/2025
Prof. Kwang-Hyun Cho is chair of the Drug Discovery, Development & Resistance session at #ICSB2025. Hear more information about the upcoming conference & why you should check out this session. Still time to register! ➡️ icsb2025.com @ucddublin.bsky.social @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 06/08/2025
#ICSB2025 will focus on Systems Biology for Health. If your research tackles challenges in this growing area, consider joining the conversation and submit your abstract today! For the full list of session topic, speakers & conference info: bit.ly/4k9J5IM @ucd-chas.bsky.social @ucddublin.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 01/08/2025
Prof. Boris Kholodenko is co-chair of #ICSB2025 and hopes you will join us this Oct 5-9! "Our conference will feature a wide range of exciting topics to show what systems biology can do for health. I hope to see you in October in Dublin!" Register now: bit.ly/4450v3F @precisiononcire.bsky.social
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Nils Blüthgen @molsysbio.bsky.social · 01/08/2025
Happy to chair a session on cell and pathway engineering at ICSB2025.com featuring e.g. an inspiring talk by @olivierpertz.bsky.social on pathway dynamics, cell fates and optical tools. Contributed talk deadline is today, Sept 1st for poster abstracts. Hope to see you in Dublin in October! #ICSB2025
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Systems Biology Ireland @sysbioire.bsky.social · 28/07/2025
The final day of #ICSB2025 on Thurs, Oct 9, will finish with 3 more outstanding breakout sessions. ✨Clinical Decision Support Tools ✨Evolution & Development ✨AI/ML Approaches in Systems Biology For more info: bit.ly/4mPNfGQ @ucddublin.bsky.social @ucd-chas.bsky.social @precisiononcire.bsky.social
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Precision Oncology Ireland @precisiononcire.bsky.social · 24/07/2025
⏰ Just over a week to submit your oral abstract for ICSB2025! 🗓 Oral deadline: 12, Fri 1 Aug 🗓 Poster deadline: 12, Mon 1 Sept (early submission encouraged) Session topics include: #DigitalTwins, #Cancer, #DrugDiscovery, #DataIntegration & more 🔗 tinyurl.com/4xmn2uz4 @sysbioire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 23/07/2025
Our Weds, Oct 8th programme at #ICSB2025 will have 6 more excellent breakout sessions including Drug Discovery, Development & Resistance, Digital Twin Models/Computational Avatars, and more! Register today and join in the conversation at these sessions: bit.ly/4450v3F @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 22/07/2025
Are you working at the cutting edge of systems biology? Do you have insights that could transform how we understand disease, develop therapeutics, or harness multi-omics data? If so, #ICSB2025 is the perfect stage for your research! More info ➡️ lnkd.in/eWKfAxEP @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 21/07/2025
The featured #ICSB2025 breakout sessions for Tues, October 7, include Systems Biology in Biotech, Cell Engineering & Pathway Engineering, & Systems Immunology, followed by afternoon tours of Dublin. Have you registered yet? More Info: bit.ly/4450v3F @precisiononcire.bsky.social @ucd-chas.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 18/07/2025
The 24th Annual ICSB takes place Oct 5-9. We have a number of exciting breakout sessions in the programme, including Systems Biology in 4D, Metabolic Diseases, Infection & Inflammation & more! See all session topics on the conference website: bit.ly/4mPNfGQ #ICSB2025 @ucddublin.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 04/07/2025
New Post now open in SBI, details below. If you're interested or would like to get more information, please send us a DM or contact sbiadmin@ucd.ie. #jobfairy #researchscientist #cancerresearch #drugdiscovery
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Systems Biology Ireland @sysbioire.bsky.social · 04/07/2025
Are you a student/postgrad studying #SystemsBiology, #Bioinformatics, #PersonalisedMedicine, #ComputationalModelling or other related fields? Check out the affordable student rates for #ICSB2025! Register today & join us at this exceptional conference! bit.ly/4450v3F @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 04/07/2025
As part of the #ICSB2025 programme, we've organised 3 half-day tours on Oct 7 from 2pm. These experiences are a perfect way for delegates to immerse themselves in Dublin’s rich history, dynamic culture, & lively charm! 🏛️🍺🫖🚌🎶 Details & Registration: bit.ly/4450v3F @precisiononcire.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 19/06/2025
📢Great news! The abstract submission deadline for #ICSB2025 has been extended, allowing for broader participation & a more diverse scientific program. Oral presentations deadline: 12 PM, 1 Aug Poster presentations deadline: 12 PM, 1 Sept Submit now: bit.ly/4k9J5IM @ucddublin.bsky.social
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Nils Blüthgen @molsysbio.bsky.social · 17/06/2025
Tomorrow (Wednesday) is abstract deadline, so send your abstract quickly!
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Systems Biology Ireland @sysbioire.bsky.social · 12/06/2025
Still time to apply -- this post closes at 12 PM today! SBI is looking for a postdoc level 1 or 2 to work on a project focused on drug resistance in KRAS-mutant pancreatic cancer. Please share! #jobfairy #postdoc #cancerresearch www.ucd.ie/sbi/aboutus/...
media.tenor.com
a blue background with the words we 're hiring on it
ALT: a blue background with the words we 're hiring on it
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Systems Biology Ireland @sysbioire.bsky.social · 09/06/2025
🗓️Don't forget! TODAY is your final chance to register for #ICSB2025 at the Early Bird Rate! Also be sure to check out our amazing roster of speakers plus the full conference programme, now available on the event website: icsb2025.com #SystemsBiology #PersonalisedMedicine #Bioinformatics
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Systems Biology Ireland @sysbioire.bsky.social · 28/05/2025
Delighted to spend Tuesday taking part in the Children's Cancer Unit Charity Research Workshop at @qubelfastofficial.bsky.social where we discussed with colleagues how to further promote cross-border collaborations in paediatric oncology research. 💛 @precisiononcire.bsky.social #childhoodcancer
Prof. Walter KolchProf. Jonathan BondDr. Amelie Trinquand
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Systems Biology Ireland @sysbioire.bsky.social · 26/05/2025
Hear from SBI's Walter Kolch as he explains why #ICSB2025 is a must-attend event for all who are interested in #systemsbiology applications for health. Join us in Dublin this Oct for fantastic speakers & diverse session topics! @ucddublin.bsky.social @precisiononcire.bsky.social
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Precision Oncology Ireland @precisiononcire.bsky.social · 23/05/2025
Congratulations to all authors on this study just published in Neoplasia, which not only demonstrated influence of saturated fat on cancer progression in the oesophagus but provides a wonderful example of the collaborative strength of the POI consortium tinyurl.com/yc7aaeb4 @sysbioire.bsky.social
tinyurl.com
Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett’s oesophagus compared to monounsaturated fat, particularly in contrast to oesophag...
Obesity-related oesophageal adenocarcinoma (OAC), arising from Barrett’s oesophagus (BO), incidence rates are rising coincident with high-fat diets. H…
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Research Ireland @researchireland.ie · 23/05/2025
We are pleased to announce the first Research Ireland Forum will take place on Thursday, 5th June 2025. While in-person attendance is by invite only, we invite you to register now to join us online and take part in this important event. Register here: www.researchireland.ie/news/forum/
Research Ireland Logo
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Systems Biology Ireland @sysbioire.bsky.social · 23/05/2025
Just 1 week left for Early Bird Registration - deadline is Fri, May 30! Don't miss out on the best rates for ICSB 2025 in Dublin this Oct 5- 9. Register now & secure your place: icsb2025.com @ucddublin.bsky.social #ICSB2025 #SystemsBiology #MedicalResearch #BioTech #NetworkBiology #AI
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Systems Biology Ireland @sysbioire.bsky.social · 20/05/2025
📢Introducing our 5 exceptional Plenary Speakers for #ICSB2025: Dong-Yup Lee, Ines Thiele, Kathryn Lilley, Rune Linding & Sabrina Spencer. For more info & the list of Invited Speakers icsb2025.com ‪@linding.bsky.social‬ ‪@inesthiele.bsky.social‬ @precisiononcire.bsky.social @ucddublin.bsky.social
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Systems Biology Ireland @sysbioire.bsky.social · 16/05/2025
May Research Spotlight out now! Read about the important ovarian cancer study published by Donal Brennan & colleagues in Science Immunology & how its findings may impact future understanding & treatment of the disease. @precisiononcire.bsky.social @ucddublin.bsky.social www.ucd.ie/sbi/research...
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Silicon Republic @siliconrepublic.bsky.social · 14/05/2025
Ireland will be placing a stronger focus on higher education, research and skills as the “foundational pillars” for its forthcoming economic strategy.
siliconrepublic.com
Higher-ed minister promises to strengthen Irish research
At a recent IUA event, Minister James Lawless set out his visions for the future of Ireland's research and innovation.
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Precision Oncology Ireland @precisiononcire.bsky.social · 16/05/2025
Powerful article published today to mark #worldbarrettsday, highlighting the importance of early detection in #OesophagealCancer. POI is enabling development of patient biobanks to support vital research and work towards better patient outcomes #ResearchisCare
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Systems Biology Ireland @sysbioire.bsky.social · 13/05/2025
Check out the wonderful feature in @siliconrepublic.bsky.social on SBI/POI Investigator, Luis Iglesias-Martinez, as he discusses the MAGIC-I programme & the promising future of using AI for better childhood cancer treatment. @precisiononcire.bsky.social www.siliconrepublic.com/machines/ucd...
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Systems Biology Ireland @sysbioire.bsky.social · 12/05/2025
Have you registered yet for the 24th Annual International Conference on Systems Biology (#ICSB2025)? Join us Oct 5-9 as we celebrate the best in systems biology research in Dublin! - Early Bird Deadline: Fri, May 30 - Abstract Deadline: Mon, June 2 icsb2025.com @ucddublin.bsky.social #systemsbiology
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Precision Oncology Ireland @precisiononcire.bsky.social · 12/05/2025
Great to see this paper published straight after World Ovarian Cancer Day: new research from Prof. Donal Brennan & collaborators highlights a potent immunosuppressive effect of lipids within ovarian ascites and a potential new avenue for development of immunotherapies www.ucd.ie/medicine/new...
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Systems Biology Ireland @sysbioire.bsky.social · 12/05/2025
New SBI/POI paper from D Brennan & colleagues examining immunosuppressive microenvironment of #ovariancancer w/ potential implications for future therapies. Read more ⬇️ @precisiononcire.bsky.social @ucddublin.bsky.social @harvardmed.bsky.social @univ-amu.fr www.ucd.ie/medicine/new...
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