This Perspective proposes the use of an integrative embedded ethics approach to evaluate human stem-cell-based embryo models and outlines a nested benchmarking strategy to periodically evaluate their scientific and ethical status.

Nature Cell Biology - This Perspective presents a set of attributes by which to evaluate human stem cell-based embryo models that not only include morally relevant embryo features but also take...

An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

Properly understood, the integrated/non-integrated distinction was not just a technical shorthand for the presence or absence of particular tissues.

IMBA - Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at t...

An optical pooled cell profiling platform (PERISCOPE) based on Cell Painting and optical sequencing of molecular barcodes was used to develop the first unbiased genome-wide morphology-based perturbati...

Pieterjan Dierickx; BMAL1 is a critical regulator of sex-specific gene expression in the heart, Function, , zqaf004, https://doi.org/10.1093/function/zqaf0

Conventional human pluripotent stem cells (hPSCs) are widely used to study early embryonic development, generate somatic cells, and model diseases, with differentiation potential aligned to a post-imp...

Conventional human pluripotent stem cells (hPSCs) are widely used to study early embryonic development, generate somatic cells, and model diseases, with differentiation potential aligned to a post-imp...

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