We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

Communications Biology - Moderate overexpression of Myc promotes heart function recovery after ischemia, leading to functional and morphological improvements with a hyperplastic phenotype through...

A molecular analysis of axolotl limb regeneration has identified a positive genetic circuit that maintains posterior cell identity and can be used to reprogramme anterior cells into posterior cells.

imageimageSignals from the epicardium are essential for fetal coronary lymphangiogenesis. VEGFC and VEGFD produced by the epicardium target the subepicardial space, where they are essential for the formation of the lymphatic vasculature in a dose-...

Cancer mutations in the PIK3CA gene cause congenital disorders. The endothelium is among the most frequently affected tissues in these disorders, displaying aberrant vascular overgrowth in the form of...

Eph/ephrin signaling is crucial for organizing retinotopic maps in vertebrates. Unlike other EphAs, which are expressed in the embryonic ventral retina, EphA4 is found in the retinal ganglion cell (RG...