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Martin Leeb

@leeboratory.bsky.social
644 followers 618 following 15 posts

Associate Professor at the Max Perutz Labs of the University of Vienna The Leeboratory Stem Cells, Pluripotency, Cell Fate

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Reposted by Martin Leeb
Institute of Molecular Biotechnology @imbavienna.bsky.social · 12/08/2026
We are hiring! Join the de Groot Lab as a Master's Student / Research Intern in Computational Biology and Theoretical Modeling to develop a Bayesian method for comparing single-cell datasets by explicitly modeling measurement noise to bring out true biological variability.
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Martin Leeb @leeboratory.bsky.social · 21/07/2026
A newly minted PhD from the lab! Congratulations, Luis, on a fantastic performance and an excellent PhD defense! You can be very proud of yourself @biolm.bsky.social !
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Reposted by Martin Leeb
Vienna BioCenter PhD Symposium 2026 @vbc-phd-symposium.bsky.social · 05/06/2026
📅 Save the date: November 4–6, 2026 We are happy to announce this year’s Vienna BioCenter PhD symposium: 🔬 A trail of twists and turns: non-linear paths to discovery Join us for a symposium that celebrates the unexpected journeys behind scientific breakthroughs. Stay tuned for more details!
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Reposted by Martin Leeb
Austin Smith @ausmith.bsky.social · 09/06/2026
Postdoc position available now in the Smith Group lsi.exeter.ac.uk/groups/smith... to test the hypothesis that differentiation biases between human pluripotent stem cell lines may be eliminated by reversion to the naïve state. careers.exeter.ac.uk/vacancies/79...
lsi.exeter.ac.uk
Smith Group - Living Systems Institute - University of Exeter
Understanding pluripotency
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Reposted by Martin Leeb
Institute of Molecular Biotechnology @imbavienna.bsky.social · 27/05/2026
Register for DevSTEM by May 30: devstem.pages.ist.ac.at
devstem.pages.ist.ac.at
Development and Stem Cells Regional Meeting
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Martin Leeb @leeboratory.bsky.social · 16/04/2026
Check out our new preprint on an unexpected role of WT1 in shaping transcriptional heterogeneity in the formative epiblast before gastrulation. Led by @biolm.bsky.social with the @leeboratory.bsky.social team! Read Luis's thread and the preprint👇 www.biorxiv.org/content/10.6...
biorxiv.org
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Martin Leeb @leeboratory.bsky.social · 12/04/2026
@nicolasrivron.bsky.social and I look to recruit a postdoc through the VIP3 rogramme to investigate post-implantation development of blastoids. Contact us if you are interested, and let your colleagues who could be interested know!
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Reposted by Martin Leeb
Max Perutz Labs Vienna @maxperutzlabs.ac.at · 13/03/2026
🚨 Out now! 🧫 In a new study in @embojournal.org, PhD student @moberhuemer.bsky.social (Leeb lab) presents a simpler, feeder-free way to grow human naïve pluripotent stem cells - making the system more scalable and accessible ➡️ tinyurl.com/29wrcdru @univie.ac.at @meduniwien.ac.at
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Reposted by Martin Leeb
The EMBO Journal @embojournal.org · 17/03/2026
Eliminating the confounding effects of human pluripotent #stemcell co-culture with MEFs: @grazianomartello.bsky.social @leeboratory.bsky.social @jzylicz.bsky.social and collaborators describe a serum coating approach for feeder-free culture of naïve hPSCs link.springer.com/article/10.1...
link.springer.com
Serum coating enables feeder-free culture of naive human pluripotent stem cells preserving developmental potential - The EMBO Journal
Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organis...
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Reposted by Martin Leeb
Max Perutz Labs Vienna @maxperutzlabs.ac.at · 19/12/2025
🔬 Love science and keeping a lab running smoothly? Join the @leeboratory.bsky.social as a lab manager/research technician and help uncover how cells choose and maintain their identity 🧫 More information ➡️ tinyurl.com/y7a8he88
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Reposted by Martin Leeb
IMP @impvienna.bsky.social · 10/12/2025
SY-Stem 2026 is here! The symposium focusing on the next generation of stem cell researchers returns to the Vienna BioCenter from 11–13 March 2026. Register online: sy-stem.org
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Reposted by Martin Leeb
Max Perutz Labs Vienna @maxperutzlabs.ac.at · 19/08/2025
❕The @leeboratory.bsky.social seeks a new Master's student! Your 🫵 project will involve stem cell culture, genome engineering as well as molecular biology. It aims at elucidating the genetic circuitries that regulate cell fate decisions in the early mammalian embryo ➡️ tinyurl.com/4awtk2n3
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Reposted by Martin Leeb
Max Perutz Labs Vienna @maxperutzlabs.ac.at · 07/07/2025
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️ tinyurl.com/3yn883b8
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Reposted by Martin Leeb
Leo Otsuki @leootsuki.bsky.social · 21/05/2025
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14
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Reposted by Martin Leeb
Sally Lowell @cellysally.bsky.social · 02/05/2025
Reminder: deadline to apply for the Stem Cell Summer School is 30th May. And it's May already! So you have to apply this month! A limited number of bursaries are available. p.s. this year, the summer school coincides with the Spetses Armata Festival, so there will be a big party on the island 🙂
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Reposted by Martin Leeb
Austin Smith @ausmith.bsky.social · 16/05/2025
Exciting postdoc opportunity in our group to develop new pluripotent stem cells lsi.exeter.ac.uk/groups/smith...
lsi.exeter.ac.uk
Smith Group - Living Systems Institute - University of Exeter
Understanding pluripotency
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Reposted by Martin Leeb
Jan Żylicz @jzylicz.bsky.social · 24/04/2025
Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j @natcellbio.nature.com
rb.gy
α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology
Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...
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Reposted by Martin Leeb
Institute of Molecular Biotechnology @imbavienna.bsky.social · 05/03/2025
We’re already warming up the motors for next week’s SY-Stem Symposium, organized by IMBA and the IMP, which focuses on the next generation of stem cell researchers and gives them the opportunity to connect and share their research with their peers. Program details here: www.sy-stem.org
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Reposted by Martin Leeb
Institute of Molecular Biotechnology @imbavienna.bsky.social · 05/02/2025
SY-Stem 2025 Symposium: Registration deadline on February 15th! SY-Stem - a symposium focusing on the next generation of stem cell researchers - is organized by IMBA and @impvienna.bsky.social. Register online: bit.ly/4jekaDg Check out the program: bit.ly/4jDioM6
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Martin Leeb @leeboratory.bsky.social · 03/02/2025
Come and join us for this fantastic symposium organised by oru SMICH PhD students!
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Reposted by Martin Leeb
SMICH - doctoral college @dksmich.bsky.social · 31/01/2025
‪We're excited to announce that registration for the "Tiles of Life" Student Symposium is now open! With a fantastic lineup of guest speakers, complemented by SMICH student talks, we’re set for two inspiring days. Don’t miss out—register now! 🚀🎓✨ #TilesofLife #studentsymposium #SMICH
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Reposted by Martin Leeb
Institute of Molecular Biotechnology @imbavienna.bsky.social · 22/01/2025
Introducing the 2025 SY-Stem Speakers! This year’s symposium again features excellent speakers, and is headlined by two fantastic Keynote Speakers: Fiona Doetsch from the University of Basel and Mitinori Saitou of the ASHBi Institute of the Kyoto University.
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Martin Leeb @leeboratory.bsky.social · 21/01/2025
We are happy to contribute to this exemplary collaborative study aimed at improving the efficiency of working with human naïve ESCs without MEF feeder cells. With @grazianomartello.bsky.social‬, @jzylicz.bsky.social, @pasquelab.bsky.social, and @nicolasrivron.bsky.social tinyurl.com/5n6z9rt9
tinyurl.com
Feeder-free culture of naive human pluripotent stem cells retaining embryonic, extraembryonic and blastoid generation potential
Conventional human pluripotent stem cells (hPSCs) are widely used to study early embryonic development, generate somatic cells, and model diseases, with differentiation potential aligned to a post-imp...
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Martin Leeb @leeboratory.bsky.social · 16/01/2025
Just a few days left to submit your abstracts for a talk at the SY-Stem Symposium in Vienna! Don’t miss this chance to share your research and connect with fellow scientists. #SYStem2025
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Martin Leeb @leeboratory.bsky.social · 02/12/2024
Great paper from the Buecker Lab. Congratulations Henry, Songjie and Christa!
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