Sign in

Nivedita Sarveswaran

@neuroniv.bsky.social
635 followers 431 following 230 posts

Postdoc in pain genetics & nociceptor biology @TheCIMR | via @biokent @UCLQSIoN @YaleMed | 🇦🇺🇬🇧🇱🇰

PostsRepliesMedia
Nivedita Sarveswaran @neuroniv.bsky.social · 06/10/2026
Looks like a brilliant meeting for anyone interested in the current drug development landscape for non-opioid based pain therapies - it's an exciting time! non-opioid-pain-therapeutics.com/about-event/
non-opioid-pain-therapeutics.com
About Event - Non-Opioid Pain Therapeutics Summit
Join us for the only pain conference dedicated to advancing non-opioid pain management, and translating novel analgesic drugs into the clinic.
000
Reposted by Nivedita Sarveswaran
Dan Jagger @auditorynerves.bsky.social · 05/10/2026
Women report suffering more pain than men, a new global study shows. That was for all pain types measured, & comes amid continuing concern about the gender pain gap, which means women are less likely to be prescribed the pain relief they need. 🧪🧠 #neuroskyence www.theguardian.com/society/2026...
theguardian.com
Women suffer more pain than men across the whole body, major global study finds
Researchers looked at pain around the world and across the human lifespan, finding steepest rise happens before age 55
22413
Nivedita Sarveswaran @neuroniv.bsky.social · 05/10/2026
Annual plea for a wonderful science communicator to leverage this positive attention and write a book translating how basic science lay the foundations for Nobel discoveries - from blueprints to bench to bedside, and back again!
010
Reposted by Nivedita Sarveswaran
Thibaut Brunet @thibautbrunet.bsky.social · 05/10/2026
One reason (among many) to study protists: as a toolbox, nature is unbeatable
2459
Reposted by Nivedita Sarveswaran
Guillaume Hummel 🌱 🇪🇺 🇫🇷 🥨 🇮🇹 @guillaumehummel.bsky.social · 05/10/2026
This year’s Nobel Prize is a great reminder of something fundamental about science: curiosity-driven research and unexpected angles of attack can reveal principles with implications far beyond the original question. Glad to see this beautifully illustrated through work on a photosynthetic organism!
01210
Reposted by Nivedita Sarveswaran
Kevin Mitchell @wiringthebrain.bsky.social · 05/10/2026
Why optogenetics deserves the hype www.wiringthebrain.com/2013/09/why-... (a piece I wrote in 2013 explaining how it works and why modulating specific cell types is so key to understanding how neural circuits and systems work)
wiringthebrain.com
Why optogenetics deserves the hype
Optogenetics has come in for some stick lately, with a number of people criticising the hype that this technique generates in some quar...
413644
Reposted by Nivedita Sarveswaran
Roberto De Filippo @roberto-defilippo.bsky.social · 04/10/2026
Too many neuro preprints to keep track of, so I made a monthly ranking of the most-read ones on bioRxiv. Not a measure of quality, just what people are reading. Here's the fresh ranking for September: robertodf.github.io/biorxiv-top/
16512
Reposted by Nivedita Sarveswaran
Felix Viana @neuroviana.bsky.social · 02/10/2026
A must read for anyone interested in pain mechanisms! Sex-specific mechanisms of chronic pain | Science www.science.org/doi/10.1126/...
science.org
Sex-specific mechanisms of chronic pain
For decades, we have known that women, especially younger women, are disproportionately affected by pain disorders, including irritable bowel syndrome, endometriosis, menstrual migraines, fibromyalgia...
041
Nivedita Sarveswaran @neuroniv.bsky.social · 01/10/2026
Huge congratulations Ewan, so well deserved!!
110
Reposted by Nivedita Sarveswaran
David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 01/10/2026
David Shiffman Scientific and Environmental Consulting is proud to introduce an Omega Super Platinum level of open access publishing. For $250,000 I will read your peer-reviewed scientific paper out loud, through a megaphone, to any 5 people of your choice. Anywhere in the world!
Person shouting through a megaphone
4465
Reposted by Nivedita Sarveswaran
Dr Yvonne Couch @dryvonnecouch.bsky.social · 29/09/2026
Some changes to UKRI funding were announced in the last couple of weeks, read about the potential impact on UK science here 🧪
022
Reposted by Nivedita Sarveswaran
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 28/09/2026
“I believe that science derives its authority from…interactions within a community of people trained to interrogate evidence and answer for the conclusions they draw from it. And it is time to formalize what this means, and which sorts of human judgment cannot (or should not) be offloaded to AI.”
01411
Nivedita Sarveswaran @neuroniv.bsky.social · 27/09/2026
Tom Banton for England, our player of the match, his maiden 100 and made a nice catch! 🏏
England cricketer Tom Banton on the cricket pitch.
020
Nivedita Sarveswaran @neuroniv.bsky.social · 24/09/2026
Life lessons from the last 3 years in science: find joy, be brave and stay resilient 💪
030
Nivedita Sarveswaran @neuroniv.bsky.social · 24/09/2026
static.klipy.com
Joey's Iconic 'I'M Out' Moment from Friends
ALT: Joey's Iconic 'I'M Out' Moment from Friends
010
Reposted by Nivedita Sarveswaran
Maxim Greenberg @maxvcg.bsky.social · 23/09/2026
In related news, I read a paper from 2001 today (in Nature Genetics). There were 6 figures, but each figure was just one panel of a very simple experiment. What a beautiful world we once had...
4414
Reposted by Nivedita Sarveswaran
School of Biological Sciences @cambridgebiosci.bsky.social · 24/09/2026
For #PainAwarenessMonth, we’re highlighting some of the researchers across our School who are advancing our understanding of pain. Dr David Bulmer studies pain in gastrointestinal diseases and how the gut-brain connection could help improve treatments. 🔗 www.phar.cam.ac.uk/research/bul...
043
Reposted by Nivedita Sarveswaran
Olivia Davis @oliviadavis.bsky.social · 22/09/2026
Our latest preprint continues our investigations into spinal mechanisms of human chronic pain! We find no evidence for a loss of neurons in the dorsal horn of donors with chronic lower limb pain, and the ratio of excitatory to inhibitory interneurons also remains consistent between pain states.
276
Reposted by Nivedita Sarveswaran
John Timmer @jtimmer.bsky.social · 22/09/2026
Ok, this "there are two separate brains" thing appears to be making the rounds, and I want to be absolutely clear: this is a press office overhyping some perfectly reasonable science that won't come as a surprise to most developmental biologists.
32755238
Reposted by Nivedita Sarveswaran
Brendel @brendelbored.bsky.social · 14/07/2026
Discovered a Blockbuster dvd at the thrift store and purchased it like I was rescuing a precious scroll from the burning fires consuming the Library of Alexandria
401602122
Reposted by Nivedita Sarveswaran
Michael @michaelklamerus.bsky.social · 01/07/2026
if you have your own physical media collection, you can do your own version of the Criterion Closet where you stand in your basement by yourself and saying "oh wow, In the Mood for Love, what a film" to absolutely no one
21638336
Reposted by Nivedita Sarveswaran
Scientific American @sciam.bsky.social · 14/09/2026
Quiet rest helps with memory consolidation, the process through which newly formed memories become more stable.
scientificamerican.com
Why doing nothing is good for your brain
The case for not filling up every minute of your day
06922
Nivedita Sarveswaran @neuroniv.bsky.social · 11/09/2026
Hope all was ok in the end and we cross paths next time!
010
Nivedita Sarveswaran @neuroniv.bsky.social · 11/09/2026
Thanks Ewan, 3rd time giving this talk but every new audience I learn a new way I could communicate things better 😄
111
Nivedita Sarveswaran @neuroniv.bsky.social · 11/09/2026
And it did not disappoint! Thank you for the welcoming experience to York and the inspiring breadth of mol/cell neurobiology #NeuroBioUK26 - already looking to next time, September 17th 2027!
282
Reposted by Nivedita Sarveswaran
Dr. Rajesh Khanna of the KhannaLabUF @khannalabuf.bsky.social · 10/09/2026
JCI - Myotonic Muscle Activity Drives a Persistent Pain State Responsive to NaV1.8-directed Analgesics www.jci.org/articles/vie...
jci.org
JCI - Myotonic Muscle Activity Drives a Persistent Pain State Responsive to NaV1.8-directed Analgesics
042
Reposted by Nivedita Sarveswaran
adamezracohen.bsky.social @adamezracohen.bsky.social · 10/09/2026
We wrote a tutorial guide on voltage imaging, now out in Neuron: authors.elsevier.com/a/1nlgh3BtfH... Indicators, microscopes, and software have all advanced to the point that it's not so hard -- you can now directly watch the electrical activity of neurons in live animals or in culture.
authors.elsevier.com
Please wait whilst we redirect you
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
33015
Nivedita Sarveswaran @neuroniv.bsky.social · 10/09/2026
Finally made it to NeuroBio, looking forward to meeting more UK molecular and cellular neuroscientists tomorrow! #NeuroBioUK26
Navy sign on a stonework wall, above metal doors, saying “Welcome to York”. A version of the York coat of arms sits above - a red cross on a white shield, and 5 gold lions within the cross.
030
Reposted by Nivedita Sarveswaran
Nicole Rust @nicolecrust.bsky.social · 10/09/2026
Well deserved! When I was searching for an example of how a discovery about the brain unlocked an entirely new class of therapies (while writing Elusive Cures), orexin is what I pointed to. It doesn't always happen this way. When it does **it's epic** and we should celebrate.
1186
Reposted by Nivedita Sarveswaran
Kirsty Grainger @handle.invalid · 10/09/2026
Here is the details from UKRI (I've not yet read) www.ukri.org/news/ukri-mo...
056
Reposted by Nivedita Sarveswaran
Wendy Bickmore @wbickmor.bsky.social · 08/09/2026
It was great working with students Kun and Ryan and @hannahlong.bsky.social, combing the literature to try and find examples of bona fide disease-causing variants in non-coding elements - promoters, enhancers and silencers. www.nature.com/articles/s41...
nature.com
Mechanisms underlying disease-causing variants in promoters and enhancers - Nature Genetics
This Review discusses how rare-disease-causing variants in the noncoding genome impact gene regulation, why these examples are so few and how new approaches could accelerate discovery of noncoding var...
16424
Reposted by Nivedita Sarveswaran
CamRARE (Cambridge Rare Disease Network) @camrare.bsky.social · 08/09/2026
Join us on Wed 7 Oct for a packed programme of talks, panels and interactive workshops at #RAREsummit26 - exploring policy, care, health data, partnerships and innovation. 📍 Cambridge or online 🎟️ Programme & tickets: camraredisease.org/raresummit26... #RareDisease #RareConditions
A rare summit graphic with photos of previous summit events and title: Agenda is now available to view.
042
Reposted by Nivedita Sarveswaran
Journal of Cell Biology @jcb.org · 08/09/2026
Using iPSC-derived human #neurons gene-edited to express pathogenic #KIF1A variants, @aikenlab.bsky.social, @erikaholzbaur.bsky.social et al. demonstrate that distinct alterations in KIF1A motor function disrupt synaptic development through divergent cellular mechanisms rupress.org/jcb/article/...
062
Reposted by Nivedita Sarveswaran
James Briscoe @jamesbriscoe.bsky.social · 07/09/2026
New book chapter from @jcornwallscoones.bsky.social & me On GRNs as dynamical systems. Wiring diagrams alone can't predict network behaviour. Understanding developmental patterning needs quantitative, experimentally defined rules for how CREs integrate TF inputs books.google.co.uk/books?hl=en&...
books.google.co.uk
Open Questions in Developmental Biology
This book explores the enduring and emerging questions in developmental biology, offering a comprehensive overview that bridges traditional concepts with the innovative inquiries shaping future resear...
13310
Reposted by Nivedita Sarveswaran
Development @dev-journal.bsky.social · 05/09/2026
Laminin β4 is required for the development of human peripheral sensory neurons Read this Research Article from our special issue #DevSIextracellular by Kenyi Saito-Diaz @kenyisama.bsky.social, Nadja Zeltner and colleagues. journals.biologists.com/dev/article/...
LAMB4 is necessary for SN development and survival. (I) Degeneration of LAMB4+/+, LAMB4+/− and LAMB4−/− SNs. Cells were cultured in plates coated with fibronectin and poly-L-ornithine, and reduced NGF concentration (1 ng/ml). Cells were fixed and stained for TUJ1 and BRN3A, and using DAPI.
041
Reposted by Nivedita Sarveswaran
Yale Neuroscience @yaleneuro.bsky.social · 04/09/2026
Researchers in the Gracheva @yaleneuro.bsky.social and Bagriantsev labs found that hibernating squirrel mechanosensory neurons—which convert touch sensation into electrical signals—are adapted to survive in low temperatures and retain their signaling capabilities.
medicine.yale.edu
How Hibernating Squirrels Retain Sense of Touch in the Cold
Mechanosensory neurons in ground squirrels retain their signaling abilities despite prolonged exposure to cold temperatures.
041
Reposted by Nivedita Sarveswaran
laura olin @lauraolin.bsky.social · 03/09/2026
If you haven’t read the dedication of Gloria Steinem’s autobiography My Life on the Road, it is really worth taking a second today.
272161476
Reposted by Nivedita Sarveswaran
Nobel Prize @nobelprize.org · 03/09/2026
We remember biochemist and chemistry laureate Ada Yonath who passed away this week at the age of 87. In 2009, Yonath shared the Nobel Prize in Chemistry with Venkatraman Ramakrishnan and Thomas Steitz for studies of the structure and function of the ribosome. Learn more: bit.ly/4kJscDU
Ada Yonath pointing at a screen, surrounded by X-ray diffraction equipment.
017129
Reposted by Nivedita Sarveswaran
Joachim Goedhart @joachimgoedhart.bsky.social · 03/09/2026
PRISM: A Plasmid-based Reporter for Intracellular Spectral Microscopy by Jonathon Nixon-Abell and team: www.biorxiv.org/content/10.6...
PRISM enables stable integration and spectrally resolved imaging of five organelles across multiple cell types.
04318
Reposted by Nivedita Sarveswaran
James Murray @james-bg.bsky.social · 02/09/2026
Should be the biggest story today by some distance. Truly mad that it isn’t. www.businessgreen.com/news/4535094...
businessgreen.com
UN: World now all but certain to 'overshoot' critical 1.5C global warming threshold
UNEP sets out 'best-case' scenario of 1.8C for global average temperature rise, but maintains world can still limit, adapt to, and eventually reduce warming to or below 1.5C threshold in future
6146102
Reposted by Nivedita Sarveswaran
Itai Yanai @itaiyanai.bsky.social · 31/08/2026
Nobel Prize winner Ada Yonath sadly passed away today. She was a legend for her pioneering work on the structure of ribosomes.
191913394
Reposted by Nivedita Sarveswaran
Elizabeth Sypek @elizabethis.bsky.social · 31/08/2026
There are multiple pain-relation NIH positions are open! Reach out for more info.
011
Reposted by Nivedita Sarveswaran
MRC-LMB Cell Biology Division @cellbiol-mrclmb.bsky.social · 28/08/2026
Great tribute to the discovery by Barbara Pearce of clathrin, the first protein found to act in membrane traffic, along with her mentoring and support of the pioneers (many of whom were other women) who revealed the workings of this key player in cellular function.
03419
Reposted by Nivedita Sarveswaran
Melanie D. White @melaniedwhite.bsky.social · 28/08/2026
Happy #FluorescenceFriday! 🔥 Neural crest cells are bringing the heat again! These migrating cells weave through the developing quail embryo, leaving beautiful patterns in their wake. 😍🧪🔬 📷 @siewzhuan.bsky.social 🔬
05011
Reposted by Nivedita Sarveswaran
Jeremy Berg @jeremymberg.bsky.social · 25/08/2026
Special bonus quote of the day The way I see it, if you want the rainbow, you gotta put up with the rain. Dolly Parton
011419
Reposted by Nivedita Sarveswaran
Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
18455329
Nivedita Sarveswaran @neuroniv.bsky.social · 21/08/2026
Kudos to bsky.app/profile/crai... if you want a weekly reminder 🍻
bsky.app
000
Nivedita Sarveswaran @neuroniv.bsky.social · 21/08/2026
And for the sake of balance…
static.klipy.com
Daniel Craig on SNL: 'The Weekend'
ALT: Daniel Craig on SNL: 'The Weekend'
120
Reposted by Nivedita Sarveswaran
Simon Fisher @profsimonfisher.bsky.social · 21/08/2026
Hello, human geneticist here. There is no scientific basis for attempts to define people in terms of “good” or “bad” genes - these are discredited views in service of racist ideologies. For consensus & concerns of experts in our field, see e.g. this 2020 statement from @geneticssociety.bsky.social:
Statement from the American Society of Human Genetics in 2020, countering the myth of "good genes". It reads as follows:
"Genetics demonstrates that humans cannot be divided into biologically distinct subcategories or races, and any efforts to claim the superiority of humans based on any genetic ancestry have no scientific evidence. Moreover, it is inaccurate to claim genetics as the determinative factor in human strengths or outcomes when education, environment, wealth, and health care access are often more potent factors. There is no factual basis for attempts to define communities or regions of people with "good" or "bad" genes and a century of science has debunked such claims, which can feed discredited views and racist ideologies. Unchecked, unethical application of false genetic "theories" have resulted in past atrocities from forced sterilizations to the Holocaust and can still fuel unethical social policies worldwide today. Over the decades, our field also has reflected on its own role in such now-condemned ideas, and we speak out vocally as a community and as individuals to combat their resurgence.
We must protect and advance the ethical use of genetics and genomics knowledge for the profound good it can realize, including better, more precise healthcare that leverages what we are discovering about human genetic commonality and diversity. The human genetics community dedicates itself to this goal each day, and today we are improving and saving hundreds of thousands of lives. As the ASHG community focuses on realizing the benefits of human genetics and genomics research for people everywhere, we also urge societal attention to address profound educational, economic and health inequalities that fuel differences in human experience and well-being. By pursuing all of these activities, humans can celebrate our common heritage as one people, embrace and fully tap our valued diversity, and help achieve optimal life outcomes for all."
2208102
Nivedita Sarveswaran @neuroniv.bsky.social · 19/08/2026
Measure your days not by the tasks you complete, but by the memes your feed bestow
050