Sign in

Neftaly Cruz Mireles

@neftalycm.bsky.social
452 followers 450 following 7 posts

Plant scientist 🌱🦠🧫 🇲🇽 | Postdoc at the University of Zurich in the Cyril Zipfel and Pedro Beltrao groups, studying protein phosphorylation during plant–microbe interactions #EMBOfellow | @thesainsburylab.bsky.social alumni

PostsRepliesMedia
Reposted by Neftaly Cruz Mireles
Fantin Mesny @mesny.bsky.social · 01/10/2026
5 years ago, @hacquardst.bsky.social and I became very interested in 𝑃𝑙𝑒𝑐𝑡𝑜𝑠𝑝ℎ𝑎𝑒𝑟𝑒𝑙𝑙𝑎 𝑐𝑢𝑐𝑢𝑚𝑒𝑟𝑖𝑛𝑎, an emerging fungal pathogen that colonizes the roots of many plants 🌱 🍅 🌾 🆕📝 Final result of a huge team effort to uncover the bases of its multi-host compatibility👇 www.nature.com/articles/s41...
nature.com
Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts - Nature Microbiology
Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.
15928
Reposted by Neftaly Cruz Mireles
Jack Rhodes @jackrhodes.bsky.social · 10/09/2026
An embryo-derived peptide signal directs endosperm polarity in Arabidopsis
science.org
An embryo-derived peptide signal directs endosperm polarity in Arabidopsis
Angiosperm seed formation requires the coordinated development of the products of double fertilization—the embryo and the endosperm. The endosperm mediates efficient nutrient transfer from surrounding...
04722
Reposted by Neftaly Cruz Mireles
Marie-Cécile Caillaud @mc-caillaud.bsky.social · 10/09/2026
Still time to apply !
time.to
time.to
176
Reposted by Neftaly Cruz Mireles
Pedro Beltrao @pedrobeltrao.bsky.social · 09/09/2026
I made a presentation to other faculty about recent progress in general AI, to facilitate the discussion around the impact for research and teaching in biology. It could be that the slides are useful for others trying to do that same. Feel free to re-use. docs.google.com/presentation...
docs.google.com
generalAI_for research_intro.pptx
Recent AI developments and what they mean for us Quick primer on general AI models* State-of-the-art in AI agent capabilities AI agents in biology (examples) Discussion - what does this mean for our r...
79026
Neftaly Cruz Mireles @neftalycm.bsky.social · 09/09/2026
Very excited to present our work at the MechanoBioTalks next week! Thank you very much @green-te.bsky.social the opportunity and for bringing ECRs together.
085
Reposted by Neftaly Cruz Mireles
Cecilia Borassi @ceciborassi.bsky.social · 20/08/2026
Sign up for the upcoming MechanoBioTalk by Neftaly Cruz Mireles (University of Zurich): "Defining protein phosphorylation networks at the plant–pathogen interface"- 16th September 2PM CET. Find the registration link and more information in our website: green-te.nl/activities/ @green-te.bsky.social
green-te.nl
Activities - GreenTE
Activities Webinars ”MechanoBioTalks – Mechanics, Materials and Living Matter” is a webinar series supported by the GreenTE consortium and organized […]
035
Reposted by Neftaly Cruz Mireles
Mariana Schuster @marischuster.bsky.social · 07/09/2026
I'm excited to share that my newly funded #ERCStG FRONTERA is recruiting two postdoctoral researchers at @ipbhalle.bsky.social 🌱🔬 If you are passionate about plant immunity, proteolysis, membrane proteins, or proteomics, I'd love to hear from you. 🧵 Please RT/share!
18885
Reposted by Neftaly Cruz Mireles
Tatsuya Nobori @tatsuyanobori.bsky.social · 03/09/2026
Excited to launch our ERC project ImmuneCellState 🚀 We’ll investigate how individual plant cells respond to pathogens and explore new dimensions of plant immunity research by integrating single-cell/spatial omics, deep learning and genome editing. @thesainsburylab.bsky.social @erc.europa.eu
2212619
Reposted by Neftaly Cruz Mireles
Yasin Dagdas @plantophagy.bsky.social · 03/09/2026
Congrats @delaconcepcionjc.bsky.social !!! Looking forward to see all the cool things your lab will discover!
2254
Reposted by Neftaly Cruz Mireles
Mariana Schuster @marischuster.bsky.social · 03/09/2026
Thrilled to have the opportunity to investigate the role of membrane protein proteolysis in plant immunity through the ERC Starting Grant FRONTERA! A heartfelt thank you to my mentors, friends, and family whose support, encouragement, and guidance made this possible. #ERCStG @erc.europa.eu
109718
Reposted by Neftaly Cruz Mireles
Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 03/09/2026
Super excited of obtaining a ERCstg to support our project MORPHEUS 🎉🎉 Receiving this grant is a pivotal moment for my lab at @zmbp-tuebingen.bsky.social as will allow to extend the scope of our research in cellular reprogramming using ribosome dormancy as entry point 😴🌱❄️🔬 @erc.europa.eu
2814421
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 24/06/2026
Two great talks from @thesainsburylab.bsky.social among the hot topics at #fungalGRC2026 - @gaiagaliberti.bsky.social and our alumnus @neftalycm.bsky.social @johninnescentre.bsky.social
093
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 25/06/2026
The team from @thesainsburylab.bsky.social (and Zurich) at #FungalGRC2026 at Squam Lake in New Hampshire
0243
Reposted by Neftaly Cruz Mireles
Álvaro Fernández @alvaroferfer.bsky.social · 25/06/2026
With a bit of delay, but my latest work on engineering a sensor for plant proteolysis was published online in The Plant Cell (1/5).
3109
Reposted by Neftaly Cruz Mireles
Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 24/06/2026
Our latest work on immune receptor engineering for enhanced pathogen recognition is out in @theplantcell.bsky.social academic.oup.com/plcell/artic... #NLRs #Effectors #Exo70
academic.oup.com
Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance
Engineering the barley NLR RGH2 enhances recognition of blast pathogen effectors from rice and wheat, leading to improved disease resistance.
15127
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 24/06/2026
Two great talks from @thesainsburylab.bsky.social among the hot topics at #fungalGRC2024 - @gaiagaliberti.bsky.social and our alumnus @neftalycm.bsky.social @johninnescentre.bsky.social
071
Reposted by Neftaly Cruz Mireles
Pedro Beltrao @pedrobeltrao.bsky.social · 23/06/2026
Switzerland and the UK making the most of their participation in the EU research funding initiatives with Switzerland tied with Germany for the largest number of grants in life science.
185
Reposted by Neftaly Cruz Mireles
Audrey K Ward @audreykward.bsky.social · 23/06/2026
No talk summaries at the Fungal GRS/C, but the GRS attendees do have a mascot we’ve adopted: Behold, the Lobfather! #FungalGRC
055
Reposted by Neftaly Cruz Mireles
Camilla Molinari @camilla-moli.bsky.social · 22/03/2026
What an amazing #Fungal26✨ Feeling very inspired– thank you to everyone who shared science and ideas! Thank you to the organisers for my poster award, @gensocuk.bsky.social for sponsoring my attendance and huge thank you @talbotlabtsl.bsky.social for these past years! I will miss the Talbot Lab.
1369
Reposted by Neftaly Cruz Mireles
Fantin Mesny @mesny.bsky.social · 29/04/2026
🎉 📰 Very happy to share the journal publication of our manuscript "Plant-associated fungi co-opt ancient antimicrobials for host manipulation"! #ScienceAdvancesResearch @science.org @teamthomma.bsky.social www.science.org/doi/10.1126/...
science.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Fungal effectors may have evolved from ancient antimicrobials, shaping plant microbiota and immunity during infection.
69649
Reposted by Neftaly Cruz Mireles
Tatsuya Nobori @tatsuyanobori.bsky.social · 20/04/2026
Thanks, Nef! It was an honour to visit the University of Zurich as a postdoc-invited speaker. Great to catch up with so many people. The Botanical Garden was amazing!
0172
Neftaly Cruz Mireles @neftalycm.bsky.social · 20/04/2026
Thank you very much @tatsuyanobori.bsky.social for an inspiring talk at the Botanical Garden, Zurich last Friday. There is still so much to learn about plant immune responses at the single cell level! @thesainsburylab.bsky.social #IPMB #FridayForum
0233
Neftaly Cruz Mireles @neftalycm.bsky.social · 26/03/2026
Join us to celebrate the 50th anniversary of the Fungal Cell and Molecular Biology Gordon Conference #GRC26 Oral presentations will be selected from abstracts. Limited places available. GRS 👉🏽 shorturl.at/vRdwY GRC 👉🏽 shorturl.at/pjhg0
041
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 18/03/2026
Magnagenes- an open science resource for the Magnaporthe research community with many new functions is being developed ⁦ @thesainsburylab.bsky.social ⁩ by Neha Sahu ⁩ #Magnafest26 #Fungal26
0165
Reposted by Neftaly Cruz Mireles
Angus Bucknell @ahbucknell.com · 18/03/2026
I’ll be talking today at the #Fungal26 concurrent session: AI in Fungal Research. I’ll be presenting on protein design in M. oryzae at 15:20 in the Fred Farr Forum. I’ll also be presenting my poster (#651A) tonight - come say hi!
072
Reposted by Neftaly Cruz Mireles
Euan Cawston @euan-cawston.bsky.social · 16/03/2026
On my way to #Fungal26! I'll be speaking at #MagnaFest presenting work on regulation of Pmk1, a key component of fungal pathogenesis. If you wanna chat I'll be at poster 652A from 7pm on the 18th. Looking forward to seeing everyone there! @thesainsburylab.bsky.social @genetics-gsa.bsky.social
197
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 17/03/2026
Euan Cawston on investigating the role of Mst7 and identifying potential scaffolds of the Pmk1 MAPK pathway #Magnafest26 #Fungal26 @thesainsburylab.bsky.social
0144
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 17/03/2026
Here is our very own 'PhosphoJave' Bautista introducing his family of phosphorylated fungal effectors and their potential regulation #Magnafest26 #Fungal26
0195
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 19/03/2026
Phosphoproteomic analysis of TOR signalling during appressorium development of Magnaporthe ⁦‪@mattwengler.bsky.social ‬⁩ #fungal26
1338
Reposted by Neftaly Cruz Mireles
Roger Castells @rcastellsg.bsky.social · 10/03/2026
Hot off the press! I'm thrilled to share that our paper "Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM" has been published! Link to the paper: www.pnas.org/doi/10.1073/... Nature is full of remarkable protein nanomachines, and now we can watch one more in action.
26920
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 10/03/2026
New Dispatch article on the multitude of fungal symbionts now being reported in lichens, led by @puginiercamille.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Fungal symbioses: A multiplicity of fungi in the lichen union
Increasing evidence suggests that lichens are not just a partnership between one fungus and one alga or cyanobacterium but may contain multiple intera…
13615
Reposted by Neftaly Cruz Mireles
Isabel Monte @isabelmonte.bsky.social · 02/03/2026
Join us at the #SEBconference Florence 2026 to discuss #Plant Robustness! 🌱🔥 @kaspervangelderen.bsky.social and I are organising the P12 session "Plant robustness from molecules to ecosystems" with the support of @greenrobust.de Check the program and submit your abstract by March 6th! 👇
02418
Reposted by Neftaly Cruz Mireles
Clémence Marchal @clemmar.bsky.social · 02/03/2026
There is a week left to apply for two available positions in my lab @ipbhalle.bsky.social - PhD: ipb-halle.mhm.jobs/12-phd-posit... - Postdoc: ipb-halle.mhm.jobs/13-postdocto... Earliest start date: 01/05/2026. We are interested in plant immune receptor biochemistry and evolution. Please share!
03639
Neftaly Cruz Mireles @neftalycm.bsky.social · 28/02/2026
Thank you @marischuster.bsky.social for accepting our invitation and for sharing with us your exciting science. The world of proteases is fascinating!
191
Reposted by Neftaly Cruz Mireles
Mariana Schuster @marischuster.bsky.social · 28/02/2026
I was honored to be invited by the postdocs at the University of Zürich for a visit and a talk. The full schedule was far too short for so much great science and Zürich in spring is just lovely. Special thanks to @giurassicpark.bsky.social for the impeccable organization!
1311
Reposted by Neftaly Cruz Mireles
Giuliana Hessler @giurassicpark.bsky.social · 28/02/2026
It was a pleasure to host you, @marischuster.bsky.social. Thank you for all the inspiring scientific discussions and sharing your protease fascination with us.
0112
Reposted by Neftaly Cruz Mireles
charpentiermyriam.bsky.social @charpentiermyriam.bsky.social · 11/02/2026
My lab at the JIC is recruiting 3 PDRA: 🔹 Bioinformatics / AI 🔹 Molecular Biology / Genetics 🔹 Proteomics Programme funded by the Novo Nordisk Foundation. 📅 Closing date: 27 February Apply via JIC website: www.jic.ac.uk/vacancies/ Please share with outstanding candidates. 🙏
jic.ac.uk
Postdoctoral Researcher (Charpentier Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.
03337
Reposted by Neftaly Cruz Mireles
Spoel Lab @spoel-lab.bsky.social · 09/02/2026
Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾
26745
Reposted by Neftaly Cruz Mireles
Nick Talbot @talbotlabtsl.bsky.social · 05/02/2026
Fantastic opportunity to join this exciting new group led by @delaconcepcionjc.bsky.social . Cryo-ET of infection-related development in pathogenic fungi - including rice blast - an exciting, game-changing prospect. Apply below 👇
0124
Reposted by Neftaly Cruz Mireles
Clémence Marchal @clemmar.bsky.social · 05/02/2026
Please share! We are looking for a PhD student (4 years) starting from 01/05/2026 at @ipbhalle.bsky.social! If you are interested in plant immunity, receptor biochemistry and evolution, consider applying! Deadline 09/03/2026. Application portal: ipb-halle.mhm.jobs/10-phd-posit...
ipb-halle.mhm.jobs
PhD position in biology (m/f/d) (1/2026)
Leibniz Institute of Plant Biochemistry (Halle) offers a PhD position in Biology
03748
Reposted by Neftaly Cruz Mireles
ZMBP @zmbp-tuebingen.bsky.social · 03/02/2026
📢 Job alert! @delaconcepcionjc.bsky.social, junior group leader at #ZMBP, has 2 open positions (PhD and postdoc) to investigate appressoria formation in plant pathogenic #fungi using #cryoEM and #cryoET #EmmyNoether #MPMI #plantscijob More info 👇
1119
Reposted by Neftaly Cruz Mireles
Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 30/01/2026
Please share! My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th! uni-tuebingen.de/universitaet...
085119
Reposted by Neftaly Cruz Mireles
Journal of Experimental Botany @jxbotany.bsky.social · 03/02/2026
⚙️🦠 REVIEW 🦠⚙️ Turley & Faulkner explore the function of plant heavy metal-associated domain-containing proteins and speculate about their functions at plasmodesmata by drawing from plant–pathogen interaction studies. 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪 Christine Faulkner
Fig. 2 (shortened, full legend in paper): Structurally characterized M. oryzae effectors in complex with the HMA or HMA-like domains of host target proteins and ID-NLRs. Crystal structures of (A) AVR-PikF with the HMA-like domain of OsHIPP19 from rice (7B1I) (Maidment et al., 2021); (B) APikL2A with the HMA-like domain of sHMA25 from foxtail millet (7NLJ) (Bentham et al., 2021); (C) Pwl2 with the HMA domain of OsHIPP43 from rice (8R7D) (Zdrzałek et al., 2024); (D) AVR-PikD with the HMA-like ID of Pikp-1 from rice (5A6W) (Maqbool et al., 2015); (E) AVR-Pia with the HMA-like ID of Pikp-1 (6Q76) (Varden et al., 2019); (F) AVR1-CO39 with the HMA-like ID of RGA5 from rice (5ZNG) (Guo et al., 2018). Complexes are displayed such that the HMA/HMA-like domains are in equivalent orientations. Domains from HPP/HIPP host targets are coloured light green. Domains from ID-NLRs are coloured dark green.
02317
Reposted by Neftaly Cruz Mireles
The Plant Journal @theplantjournal.bsky.social · 03/02/2026
🗣️ 𝐼𝑛 𝑐𝑜𝑛𝑣𝑒𝑟𝑠𝑎𝑡𝑖𝑜𝑛 𝑤𝑖𝑡ℎ 𝐃𝐫. 𝐂𝐲𝐫𝐢𝐥 𝐙𝐢𝐩𝐟𝐞𝐥 Cyril Zipfel, a leading voice in plant immunity, reflects on plant immune recognition, his scientific journey, and what’s next for the field 🌱🧬 interviewed by @luisdeluna.bsky.social 👉 doi.org/10.1111/tpj.70688
02311
Reposted by Neftaly Cruz Mireles
Mario Vallejo-Marin @nicrodemo.bsky.social · 28/01/2026
Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...
Uppsala in late autumn
1159185
Reposted by Neftaly Cruz Mireles
Rita Maravilha Marques @ritamaravilha.bsky.social · 29/01/2026
1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇 @thesainsburylab.bsky.social @itqbnova.bsky.social 🔗https://doi.org/10.64898/2026.01.25.701577
35322
Reposted by Neftaly Cruz Mireles
GAMA Miguel Angel @miangoar.bsky.social · 29/01/2026
The fourth lecture of the course is now available on YouTube :) We will review how Transformers and modern LLMs work youtu.be/vUpb6O6T2yQ Slides drive.google.com/file/d/1y2Vj... For now, the English version is only available through the automatic translation of the subtitles.
021
Reposted by Neftaly Cruz Mireles
Pedro Beltrao @pedrobeltrao.bsky.social · 29/01/2026
New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways www.biorxiv.org/content/10.6...
biorxiv.org
22011
Reposted by Neftaly Cruz Mireles
Frank Menke @frankmenke.bsky.social · 30/10/2025
Very greatfull to work with this brilliant and diverse bunch that make up the #proteomics team @thesainsburylab.bsky.social. #Awayday. 🇨🇦🇫🇴🏴󠁧󠁢󠁳󠁣󠁴󠁿🇬🇧🇵🇭🇬🇭🇨🇳🇨🇿🇩🇪🇳🇱
0133
Reposted by Neftaly Cruz Mireles
Andy Posbe @adnroide.bsky.social · 30/10/2025
Spooky season has arrived! 👻 We held our annual Pumpkin Carving Competition at @thesainsburylab.bsky.social —vote for your favourite carve! 🎃🕯️
8198