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Megan Harwig 🔬

@mcharwig.bsky.social
199 followers 621 following 30 posts

Mom, mitochondriac and confocal microscopist. Microscopy Core Manager at the Medical College of Wisconsin. Opinions = mine orcid.org/0000-0003-2140-5739 mcw.ilab.agilent.com/service_center…

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Reposted by Megan Harwig 🔬
Image Cooperative @image.coop · 16/03/2026
Hello, world! We are starting a worker cooperative to build, maintain, teach, and support open source scientific imaging software. image.coop/blog/posts/2...
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Megan Harwig 🔬 @mcharwig.bsky.social · 26/11/2025
Know anyone looking for a microscopy sales position? Check out this job at Oxford Instruments plc: www.linkedin.com/jobs/view/43... 🔬
linkedin.com
Oxford Instruments plc hiring Territory Sales Manager in California, United States | LinkedIn
Posted 8:06:21 PM. About Oxford InstrumentsOur purpose is to accelerate the breakthroughs that create a brighter…See this and similar jobs on LinkedIn.
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Reposted by Megan Harwig 🔬
Eugene Katrukha 🇺🇦 @ekatrukha.bsky.social · 21/11/2025
Finally, the first public release of #BigVolumeBrowser, so after teasers, you can try it yourself. For details, please check the announcement post (1/2) forum.image.sc/t/bigvolumeb...
forum.image.sc
BigVolumeBrowser: a new 3D multi volume/mesh/point clould (SMLM) data viewer
Hello everyone, I’d like to share with you another 3D viewer for FIJI, BigVolumeBrowser (full documentation link). It‘s a first initial public release, so there is still space for improvements. Le...
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Reposted by Megan Harwig 🔬
Marine Biological Laboratory @mblscience.bsky.social · 28/10/2025
We are hiring an Imaging Scientis. Apply here: go.mbl.edu/AS1887
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Megan Harwig 🔬 @mcharwig.bsky.social · 29/10/2025
We are looking for perfusion/microfluidics systems that are compatible with OKO chambers on our Dragonfly spinning disk confocal microscopes in our core. Does anyone have any recommendations of products you love that do not leak? 🔬🧪🧬🥼
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Megan Harwig 🔬 @mcharwig.bsky.social · 17/10/2025
Soon our core will be getting a MicroPoint4 tool for our Dragonfly 620SR. Anyone else have a MicroPoint tool? What has been your favorite application? andor.oxinst.com/learning/vie...
andor.oxinst.com
Glia Responses after Injury with Laser Ablation in Zebrafish- Oxford Instruments
Discover how the Kucenas Lab uses our confocal microscopes and precise laser ablation to study glial development, injury response, and dynamics in Zebrafish.
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Megan Harwig 🔬 @mcharwig.bsky.social · 10/10/2025
Come work with us at MCW! This position is in the Translational Metabolomics-Preclinical Imaging Shared Resource. This position involves imaging mice, rats and other small animal models with multimodal imaging. careers.peopleclick.com/careerscp/cl...
careers.peopleclick.com
Research Scientist I
Medical College of Wisconsin - Research Scientist I - Milwaukee WI 53201
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Reposted by Megan Harwig 🔬
Sarah Cohen @cohenlaboratory.bsky.social · 13/07/2025
It has been a dream come true to lead a rotation in the @mblscience.bsky.social Physiology course - thanks to the amazing Directors @gladfelterlab.bsky.social and @brangwynnelab.bsky.social, course staff, TAs, and students!
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Reposted by Megan Harwig 🔬
CCP-volumeEM @ccp-volumeem.bsky.social · 29/05/2025
If you work in #VolumeEM, please fill in our survey to help us build a Collaborative Computational Project for volumeEM! Survey link: forms.office.com/e/eMAJGCKUnc we're aiming to identify the needs of the community in order to build a roadmap for all-things data-related in #vEM
A logo showing a stylised computer monitor, with a cube in the style of a volume electron microscopy dataset. The text below reads "CCP-volumeEM - Collaborative Computational Project for Volume Electron Microscopy"
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Reposted by Megan Harwig 🔬
Bio-protocol @bio-protocol.bsky.social · 31/05/2025
The recording of our recent webinar, "Next-generation expansion microscopy: 20× magnification in one step" by @shiweiw.bsky.social, is now available! You can access it at: bio-protocol.org/webinar/deta... #Webinar #LifeSciences
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Reposted by Megan Harwig 🔬
xipeng1.bsky.social @xipeng1.bsky.social · 16/05/2025
Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems: 🔬 Widefield → Confocal 🔬 Single-photon → Multiphoton 🔬 2D-SIM → 3D-SIM Now integrated in Airy PolarSIM and #FlexSIM! doi.org/10.1038/s415... #Microscopy #Fluorescence
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SCIENMAG @scienmag.bsky.social · 29/05/2025
Revolutionizing High-Speed Dynamic Fluorescence Imaging with Deep Learning-Enhanced Denoising Techniques Researchers have unveiled a groundbreaking advancement in the field of fluorescence microscopy, designed to resolve one of the most significant challenges facing scientists: image degradation…
scienmag.com
Revolutionizing High-Speed Dynamic Fluorescence Imaging with Deep Learning-Enhanced Denoising Techniques
Researchers have unveiled a groundbreaking advancement in the field of fluorescence microscopy, designed to resolve one of the most significant challenges facing scientists: image degradation due to noise in dynamic in vivo imaging. This innovative method, recently published in the journal PhotoniX, presents a self-supervised deep learning approach known as Temporal-gradient empowered Denoising (TeD). The newly developed technique stands to revolutionize the way researchers capture and analyze high-speed biological processes, which are often severely obscured by noise.
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Reposted by Megan Harwig 🔬
BioTechniques @biotechniques.bsky.social · 27/05/2025
⭐ The 2025 BioTechniques Image Competition is now open! 🔬 You have until 17 June to submit up to ten scientific images or illustrations that you’ve taken or created during your research. Prizes, rules and how to enter >>> www.biotechniques.com/life-science... 🧪 #imaging #microscopy
biotechniques.com
BioTechniques Image Competition 2025
Submit your scientific images to the BioTechniques Scientific Image Competition 2025! Enter now for the chance to win a US$200 gift card.
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Reposted by Megan Harwig 🔬
Computational and Structural Biotechnology Journal (CSBJ) @csbj.org · 27/05/2025
🤖 How resilient are deep learning models to real-world imperfections in microscopy? 🔗 Practical guidelines for cell segmentation models under optical aberrations in microscopy, DOI: doi.org/10.1016/j.cs... 📚 CSBJ Quantum Biology and Biophotonics: www.csbj.org/qbio #CellSegmentation #Microscopy
Practical guidelines for cell segmentation models under optical aberrations in microscopy. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.09.002
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Reposted by Megan Harwig 🔬
Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 21/05/2025
Today is the deadline to apply! Come hang out with our team in Boston and learn to think about bioimage analysis and how to use many fun open source tools!
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Reposted by Megan Harwig 🔬
Rita Strack @ritastrack.bsky.social · 21/05/2025
Did you know that Bioimage Archive has a specific database for people to share AI-ready imaging datasets? I did not until @yanlanmao.bsky.social told me! Please deposit! If people regularly submitted, it would have a huge collective impact on bioimage analysis. www.ebi.ac.uk/bioimage-arc...
ebi.ac.uk
BioImageArchive < The European Bioinformatics Institute < EMBL-EBI
The BioImageArchive – a free, publicly available online resource which stores and distributes biological images
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Reposted by Megan Harwig 🔬
NFDI4BIOIMAGE @nfdi4bioimage.bsky.social · 20/05/2025
Efficient, standards-based #bioimaging data management is essential for research and reuse. Join the presentation about “A Journey to #FAIR Bioimage Data,” a contribution to @ebi.embl.org's STANDFLOW project webinar series. 🗓️ July 2, 2025 | 02:30–03:30 pm 👉 Register: www.ebi.ac.uk/training/eve...
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Reposted by Megan Harwig 🔬
Nikon Microscope Solutions @healthcare.nikon.com · 19/05/2025
📄 A recent review article covers the latest in next-generation #Fluorophores and site-specific labeling strategies for different types of biomolecules, including info on their application in areas such as #SuperResolution #Microscopy: bit.ly/3Fhbeh9 #Fluorescence
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Reposted by Megan Harwig 🔬
Nature Methods @natmethods.nature.com · 19/05/2025
A suite of bridged rhodamine dyes for fluorescence microscopy, named BriDyes, offers excellent brightness, photostability, solubility, cell permeability, and resistance to photoblueing. www.nature.com/articles/s41...
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Reposted by Megan Harwig 🔬
Structural Biology @actacrystd.iucr.org · 20/05/2025
Carlos Oscar S. Sorzano et al.: Image-processing methods for electron microscopy of biological specimens ... #IUCr journals.iucr.org/paper?S2059798325…
journals.iucr.org
Image-processing methods for electron microscopy of biological specimens
The focused issue on Image-processing methods for electron microscopy of biological specimens is introduced. The virtual issue is available at https://journals.iucr.org/special_issues/2025/imageprocessing.
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Reposted by Megan Harwig 🔬
Mapping Ignorance @mappingignorance.org · 15/05/2025
By democratizing bioimage analysis, BiaPy is paving the way for faster, more inclusive scientific breakthroughs, bringing us closer to understanding the building blocks of life. mappingignorance.org/2025/05/15/bia…
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Reposted by Megan Harwig 🔬
brunosbiologs.bsky.social @brunosbiologs.bsky.social · 15/05/2025
Ever wonder which microscopes power today’s life science breakthroughs? 🧬🔬 I put together a quick guide—from brightfield to holography. Check it out 👉 www.linkedin.com/pulse/seeing... #Microscopy #LifeSciences #Biotech #SpatialBiology #ImagingScience #SciComm
linkedin.com
Seeing Is Believing: The Microscopes Powering Modern Life Sciences
As someone who works closely with life science researchers and imaging technologies, I often get a surprisingly common question: "You sell microscopes? Like for high school labs? Or on Amazon? Or for ...
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Reposted by Megan Harwig 🔬
Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈 @aesposito1975.bsky.social · 11/05/2025
Good morning! Today we publish three new #MicroscoPills about #confocal #microscopy. E03 - What is it and why is it useful in #biology E04 - Confocal microscopy history and evolution E05 - The role of the confocal #pinhole Follow us on Spotify open.spotify.com/show/20hJTM4... #science
open.spotify.com
MicroscoPills: your bite-sized dose of microscopy concepts
Podcast · Dr Alessandro Esposito · Unlock the tiny world with short episodes on microscopy and its application to biology and biomedical research. Discover how these tools visualise life at the molecu...
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Reposted by Megan Harwig 🔬
voigtvision.bsky.social @voigtvision.bsky.social · 08/05/2025
Thanks to expansion microscopy, clever labeling, and modern segmentation approaches, doing connectomics with #light #microscopy has become feasible - huge congratulations Mojtaba & the Danzl lab at @istaresearch.bsky.social ! www.nature.com/articles/s41...
nature.com
Light-microscopy-based connectomic reconstruction of mammalian brain tissue - Nature
A technique called LICONN (light-microscopy-based connectomics) allows mapping of brain tissue at synapse level and simultaneous measurement of molecular information, thus enabling quantification of c...
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Reposted by Megan Harwig 🔬
Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 05/05/2025
FREE Help with Bioimage Analysis!
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Reposted by Megan Harwig 🔬
EMBO @embo.org · 06/05/2025
Deadline extended to 19 May! 🧪 Learn about light sheet #microscopy, sample preparation, data processing and #ImageAnalysis. Apply now for EMBO Practical Course on Light sheet microscopy in Dresden, Germany, 11–22 August meetings.embo.org/event/25-lsm #EMBOlsm #imaging #EMBOevents
meetings.embo.org
Light sheet microscopy
Light sheet microscopy is a technology that enables near-isotropic imaging of large biological specimens over time. It opens new avenues to study biological processes with unprecedented imaging speed…
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Reposted by Megan Harwig 🔬
Perrine Paul-Gilloteaux @perrinegil.bsky.social · 05/05/2025
You can now apply until the 4th of June !! #EMBOBioImage www.embl.org/about/info/c...
embl.org
Advanced methods in bioimage analysis
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Reposted by Megan Harwig 🔬
Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 01/05/2025
BIG NEWS - for the first time ever, we're running a Bioimage Analysis Beginnings Bootcamp. Learn #bioimageanalysis from awesome folks, and gain familiarity with some new tools as well as how to pick the right tool in the first place. Aug 4th-8th - apply here (soon!) forms.gle/d2fCXsrWHVP8...
Ad for the Bioimage Analysis Beginnings Bootcamp at the Broad Institute. 

Where & When
Broad Institute, 415 Main Street, Cambridge MA (in-person only)
Monday–Friday, August 4–8, 20259:00 AM – 5:00 PM

About the Bootcamp
Learn core bioimage analysis skills using open-source tools for light
microscopy in this hands-on, in-person course. The Bootcamp
covers annotation, segmentation, and deep learning fundamentals.

Fee: $600 (Academic/Non-Profit) | $1000 (Industry/For-Profit)
For more information email ImagingAdmin@broadinstitute.org
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/05/2025
"I’ve heard a lot of panic in the community as if the support that the federal government has for science has ended and that science is no longer the priority. One of the reasons I was delighted to be able to come here was to assure people that is not true" #NIH www.jsonline.com/story/news/p...
jsonline.com
Trump's NIH director takes questions at Medical College of Wisconsin amid broad research cuts
President Trump's new NIH director took questions from Medical College of Wisconsin researchers, including one whose research grant had been canceled.
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Reposted by Megan Harwig 🔬
Ishier Raote @ishier.bsky.social · 16/04/2025
On April 19, 1898, Camillo Golgi described what we now know as the #Golgi apparatus - a structure so pretty and unusual it took over fifty years for the scientific community to agree it wasn’t just an artefact. April 19 is #GolgiDay! Mark your calendars to honour the best organelle.
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Reposted by Megan Harwig 🔬
Nature @nature.com · 13/04/2025
If you want to understand how cells function, you have to work out what proteins interact with — and where go.nature.com/3RgNXOZ
go.nature.com
Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives
Nature - Spatial proteomics is helping biologists to uncover how cells work by mapping where proteins operate.
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Reposted by Megan Harwig 🔬
Dave Barry @david-j-barry.bsky.social · 13/04/2025
Image Analysis job opportunity in the thoroughly amazing city of Copenhagen! employment.ku.dk/all-vacancie...
employment.ku.dk
Bioimage Analyst and Python programmer at Danish BioImaging Infrastructure Image Analysis Core Facility (DBI-INFRA IACF)
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Reposted by Megan Harwig 🔬
Dave Matus @davematus.bsky.social · 11/04/2025
#hiring! come join us at the Advanced BioImaging Center at UC Berkeley to help us build the #CellObservatory! 1/2 aprecruit.berkeley.edu/JPF04858
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Reposted by Megan Harwig 🔬
Alt CDC (they/them) @altcdc.altgov.info · 12/04/2025
ATTENTION CDC AND ALLIES We have power together. To see our strength and build community, we ask that you wear something 💚green💚 to work on WEDNESDAY to show solidarity and readiness to defend public health Spread the word! TYSM@rndidi.bsky.social #courageiscontagious #wearthecolor #spreadthecolor
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Reposted by Megan Harwig 🔬
Andreas Tolias @andreastolias.bsky.social · 11/04/2025
After 7 years, thrilled to finally share our #MICrONS functional connectomics results! We recorded activity from ~75K neurons in the visual cortex of a single mouse, then mapped its wiring using electron microscopy. nature.com/immersive/d42859-025-00001-w/index.html
nature.com
The MICrONS Project
An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation...
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allen institute @alleninstitute.org · 11/04/2025
Good news, mitochondria fans. Our #CellLineOfTheWeek is is Tom20 - illuminating the powerhouse of the cell! 🧫 Our cell lines & plasmids are available for just the cost of shipping to support discovery. 📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social #FluorescenceFriday
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Global BioImaging @globalbioimaging.bsky.social · 10/04/2025
🎙️Global BioImaging Facility Management 2025 Course is open for applications! 📅 1-3 October 2025 📌 Montreal, Canada For Imaging core facility professionals. Learn facility management, impact, strategic planning & much more. ✈️ Travel grants available Apply here: tinyurl.com/GBI-CA-2025
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Reposted by Megan Harwig 🔬
Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 07/04/2025
Delighted to announce that @erinweisbart.bsky.social and I have teamed up to create a new bioimage analysis video podcast called Ask Erin/Dear Beth - you can check it out at the link below! It will highlight common challenges in #bioimageanalysis, as well as our favorite solutions to them. (1/x)
youtube.com
Ask Erin, Dear Beth
On Ask Erin/Dear Beth, bioimage analysis experts Beth Cimini and Erin Weisbart, of the Imaging Platform at the Broad Institute of MIT and Harvard, answer your image analysis questions! Whether it’s ab...
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Reposted by Megan Harwig 🔬
Denis Wirtz @deniswirtz.bsky.social · 05/04/2025
bioRxiv has partnered with Sciencecast to produce lay summaries of posted preprints. Truly impressive. Here our paper on integrated 3D tissue mapping and nuclear morphology is well summarized and properly placed in the larger context of the field. Hear it here: sciencecast.org/casts/ij1zyh...
sciencecast.org
Science Cast
Increase your recognition in the scientific world with short video-casts
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Megan Harwig 🔬 @mcharwig.bsky.social · 05/04/2025
This was playing in my head the whole time… Clown show indeed.
media.tenor.com
a woman in a hat is standing next to another woman in a closet .
ALT: a woman in a hat is standing next to another woman in a closet .
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Reposted by Megan Harwig 🔬
Science Magazine @science.org · 03/04/2025
Ten principal investigators who were fired from the National Institute of Neurological Disorders and Stroke as part of the massive reduction in force at federal agencies on Tuesday are back at work, at least for now, Science has learned.
scim.ag
After ‘coding error’ triggers firings, top NIH scientists called back to work
Neuroscience institutes tells 10 scientists placed on leave it’s working on a “long-term” solution to officially reinstating them
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Reposted by Megan Harwig 🔬
Marisa Kabas @marisakabas.bsky.social · 03/04/2025
Updated just now. Six pages so far. The breadth of destruction is staggering.
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/04/2025
Just heard NINDS PIs have been reinstated. What a temporary nightmare.
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/04/2025
I hope that is true.
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/04/2025
I spent 6 years working in Richard’s lab while I was earning my PhD. He is an amazing scientist who goes where the science leads him and has significantly impacted so many fields. This is awful and heart wrenching.
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/04/2025
I spent 6 years working in Richard’s lab while I was earning my PhD. He is an amazing scientist who goes where the science leads him and has significantly impacted so many fields. This is awful and heart wrenching.
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Megan Harwig 🔬 @mcharwig.bsky.social · 03/04/2025
Richard Youle is my PhD mentor🤯🤬😭. 40 yrs at NIH, award winning scientist should not end this way.
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 01/04/2025
At least a dozen senior, innovative scientists that run labs at NIH have been pushed out today. They have developed new methods and techniques; some study Alzheimer’s. Where’s that focus on innovation that Bhattacharya insists he’s focused on?
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Megan Harwig 🔬 @mcharwig.bsky.social · 27/03/2025
Mitos are my favorite to image. Some days I miss doing my own experiments and imaging mitochondria. Captured this while gaining confidence on our new system. Green=Fis1 mutant; magenta=Drp1. Captured on our new Dragonfly 620 SR (decon applied). #dragonfly #mitochondria #spinningdiskconfocal #hilllab
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Journal of Cell Biology @jcb.org · 21/03/2025
In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...
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