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MRC MBU postdocs

@mbu-postdocs.bsky.social
94 followers 26 following 4 posts

Highlighting the work and contributions of @MRC_MBU postdocs. Views are our own. www.mrc-mbu.cam.ac.uk/mbu-postdocto…

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Lindsey Van Haute @lindseyvanhaute.bsky.social · 31/03/2026
Study shows that mothers are: - 29% less likely to be employed at a university - 12% reduction in earnings when they left academia - 35% decline in their chance of getting tenure - 31% fewer publications than fathers www.nature.com/articles/d41...
nature.com
Motherhood derails women’s academic careers — these data reveal how and why
Mothers in academia take on considerably more childcare-related responsibilities than do fathers.
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Reposted by MRC MBU postdocs
Alex Whitworth lab @labwhitworth.bsky.social · 05/01/2026
Drosophila models have been highly useful in dissecting the physiological roles of PINK1 and Parkin in #mitophagy Led by 3 talented PhD students, we wrote a review summarising recent exciting discoveries and discussed these in context of current in vitro studies portlandpress.com/biochemj/art...
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Mike Murphy @mitoredox.bsky.social · 06/01/2026
Congrats to Jan whose new paper on persulfide measurement is is out now in Nature Comms
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 13/01/2026
Student mental health is in crisis — here’s how to help www.nature.com/articles/d41...
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Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · 08/12/2025
📝 Online now - the Review "Structural transport and inhibition mechanism of the mitochondrial pyruvate carrier" from Edmund Kunji (@mrc-mbu.bsky.social) and co. #SLC54 #MPC #EnergyMetabolism #MembraneProteinStructure #StructureBasedDrugDesign Read it here 👉 authors.elsevier.com/sd/article/S...
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Cambridge Clinical Mitochondrial Research Group @mitocamb.bsky.social · 08/10/2025
Congratulations to @lucialugut.bsky.social who passed her PhD with flying colours last week; and with no thesis corrections ☺️🎓👏
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Michele Frison @frisophagy.bsky.social · 10/10/2025
Bluesky, I am pleased to present to you the main product of postdoc work, published in @science.org ☝️ As it turns out, the very quality control mechanism that can remove mutant mtDNA copies is the one that maintains high mutant burden, or heteroplasmy levels
High heteroplasmy decreases mitochondrial ubiquitination
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Payam Gammage @mito-oncogene.bsky.social · 03/11/2025
Excited to share our latest work in collaboration with the @edreznik.bsky.social lab @mskcancercenter.bsky.social, where we describe functionally dominant mitochondrial DNA mutations in patient tumors. So, what is functional dominance in mitochondrial genetics, I hear you ask? rdcu.be/eN1jm
rdcu.be
Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer
Nature Genetics - Analysis of 14,106 tumor genomes highlights recurrent mutations in mitochondrial ribosomal RNA encoded within the mitochondrial genome. Mutations occur at hotspot positions and...
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MRC MBU postdocs @mbu-postdocs.bsky.social · 02/09/2025
Congratulations!
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Mike Murphy @mitoredox.bsky.social · 24/05/2025
Congratulations to Abigail Giles who was awarded the "The Richard J. Bing Award for Young Investigators" at the recent World Congress of the International Society For Heart Research in Japan. Well done Abigail!
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MitoCarriers @mitocarriers.bsky.social · 25/04/2025
Trinity Hall covers our discovery www.trinhall.cam.ac.uk/news/unwrapp... Molecular basis of pyruvate transport and inhibition of the human mitochondrial pyruvate carrier | Science Advances www.science.org/doi/10.1126/...
trinhall.cam.ac.uk
Unwrapping the secrets of sugar metabolism - Trinity Hall Cambridge
Ever wondered why eating something sugary gives you such an energy boost? It turns out that the secret lies within our cells, specifically in tiny structures called mitochondria, often dubbed the cell...
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Reposted by MRC MBU postdocs
Lindsey Van Haute @lindseyvanhaute.bsky.social · 15/05/2025
P-hacking Removing outliers, using alternative statistical methods and running extra experiments are some methods that could be used to change the P-value. Be careful not to fall in this trap! Stay sceptical! Null results are a normal part of science. www.nature.com/articles/d41...
nature.com
P hacking — Five ways it could happen to you
Some data practices can lead to statistically dubious findings. Here’s how to avoid them.
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MitoCarriers @mitocarriers.bsky.social · 18/04/2025
Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss | EurekAlert! www.eurekalert.org/news-release...
eurekalert.org
Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss
Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the ‘powerhouses’ of our cells, allows us to make the fuel we need from s...
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Minczuk Lab @mitogene.bsky.social · 09/04/2025
Huge congrats to Pavel Nash on publishing his PhD work! 🎉 We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV. Thanks to the entire team! @mrc-mbu.bsky.social @mbu-postdocs.bsky.social #MitochondrialDisease #mtDNA www.embopress.org/doi/full/10....
embopress.org
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine
imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...
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MRC MBU @mrc-mbu.bsky.social · 24/03/2025
Well done everyone! 😎
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 27/03/2025
Mitochondria differ in type and density in different parts of the brain. For example, the evolutionarily oldest brain regions have a lower density of mitochondria than newer regions. www.nature.com/articles/d41...
nature.com
First map of human brain mitochondria is ‘groundbreaking’ achievement
Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
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Reposted by MRC MBU postdocs
Lindsey Van Haute @lindseyvanhaute.bsky.social · 25/03/2025
Shared first authorship, but who gets to be first? According to this study, there is no disadvantage to sharing credit. Weakness of the study: The test name was a gender-neutral European name. Can someone please repeat this study with female/non-European names? www.nature.com/articles/d41...
nature.com
Does sharing first authorship on a paper carry a penalty? What the research says
Study dispels myth that order of names in a paper’s author list dictates perception of success.
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Alex Whitworth lab @labwhitworth.bsky.social · 22/03/2025
@mrc-mbu.bsky.social all set to entertain the public @cambridgefestival.bsky.social Come and join us at CAST, Cambridge, and learn about our amazing work to understand all things #mitochondria in health and disease
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The EMBO Journal @embojournal.org · 03/03/2025
Thought that only purine nucleotides could inhibit mitochondrial thermogenesis in brown adipose tissue? Edmund Kunji and coworkers @mitocarriers.bsky.social @mrc-mbu.bsky.social show that pyrimidines bind and inhibit UCP1 in similar manner www.embopress.org/doi/full/10....
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Mike Murphy @mitoredox.bsky.social · 09/02/2025
Glad to be a small part on this interesting paper from Milos Filipovic with actual work done by Jan Miljkovic and Alva Casey in my lab. Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation: Cell Metabolism www.cell.com/cell-metabol...
cell.com
Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation
Petrovic et al. demonstrate that ergothioneine acts as an alternative substrate for cystathionine gamma-lyase, an H2S-producing enzyme, leading to an increase of protein persulfidation. The persulfida...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/02/2025
First of two videos I made about vaccines for kids & teens! YouTube promotes videos with engagement, so likes/comments/shares help reach the right audience. Even if you're not the target, your support matters! 💙 Watch & boost? 🔗 youtu.be/KC42D0ZpqtE #SciComm #Vaccines #ScienceForEveryone
youtu.be
Are vaccines safe?
YouTube video by Simple Science
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Reposted by MRC MBU postdocs
Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/02/2025
Second of two videos I made about vaccines for kids & teens! YouTube promotes videos with engagement, so likes/comments/shares help reach the right audience. Even if you're not the target, your support matters! 💙 Watch & boost? 🔗 youtu.be/ScOQ2tt5HQQ #SciComm #Vaccines #ScienceForEveryone
youtu.be
How COVID 19 mRNA Vaccines Are Made and Work
YouTube video by Simple Science
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MRC MBU postdocs @mbu-postdocs.bsky.social · 20/01/2025
Simple science videos for kids and teens. Although you are not the primary target, you can help by liking and subscribing to help these videos reach more kids! Let’s make science fun and easy for everyone!
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RyanLab_TCD @ryanlab.bsky.social · 06/01/2025
📢Preprint alert! Very excited to share the first preprint from the lab spearheaded by stellar postdoc Eloïse Marques. An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo. 1/n www.biorxiv.org/content/10.1...
biorxiv.org
An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo
Impaired mitochondrial bioenergetics in macrophages can drive hyperinflammatory cytokine responses, but whether this may also be caused by inherited mtDNA mutations is unknown. Here, we address this q...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/01/2025
Updated list. As more and more people join bluesky, I want to share this link again. Also, it's difficult to find everyone, so react to this message if you're a (former or current) MBU member and you're not in the list yet. go.bsky.app/9ATZngh
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 18/12/2024
I asked chatGPT to make a video: A 2-minute YouTube video for teenagers explaining what mitochondria are, what they do and why they are special (e.g. own DNA, inherited from mother, bacterial origin). Here is the result: www.nextgenseqanalysis.com/videos-1/v/m... What do you think?
nextgenseqanalysis.com
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 10/12/2024
Are postdocs the overlooked backbone of academia? Despite their vital contributions, postdoctoral researchers are often stuck in precarious, temporary roles with limited stability or recognition. www.linkedin.com/posts/lindse...
linkedin.com
Lindsey Van Haute on LinkedIn: The Case for Permanent Postdocs: Rethinking Academic Career Structures
Are postdocs the overlooked backbone of academia? Despite their vital contributions, postdoctoral researchers are often stuck in precarious, temporary roles…
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 09/12/2024
www.nature.com/articles/d41...
nature.com
A science mega-programme is taking shape in the EU: what it means for researchers
A new research commissioner will help to build the European Union’s next massive science scheme — with a renewed focus on innovation.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 06/12/2024
From a young age, boys are praised for speaking up, girls for staying quiet. Boys believe their views matter more. Girls learn to smile, work quietly, defer to boys, and speak only when asked. No wonder many girls lose their voice, confidence, and ambition. www.theguardian.com/commentisfre...
theguardian.com
Why do some men behave badly? I think I have the answer
From an early age boys are treated as though they are smarter and more talented than girls. It can lead to a damaging overconfidence
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Science Magazine @science.org · 05/12/2024
Can you explain your doctoral research through interpretive dance? The 17th annual #DanceYourPhD competition is open! Submit by 28 March for a chance to win $2000: scim.ag/3BcKi0e
scim.ag
Science’s ‘Dance Your Ph.D.’ contest is open again!
This year’s competition has a special category on artificial intelligence research or quantum science—no Ph.D. needed
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/12/2024
Whether you’re a postdoctoral researcher dreaming of independent research or a seasoned researcher plotting your next move, the tips in this article will strengthen your candidacy. www.nature.com/articles/d41...
nature.com
A step-by-step guide to landing your next job in science
A road map to success based on Nature’s hiring-in-science survey, with advice for every stage from application to offer.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 20/11/2024
Research shows the heavy toll PhD studies take on mental health, with a 40% rise in psychiatric medication by the fifth year. It's time to address the pressure on doctoral students and prioritise their well-being. #PhD,#MentalHealth www.nature.com/articles/d41...
nature.com
The huge toll of PhDs on mental health: data reveal stark effects
PhD students in Sweden accessed mental-health services at increasing rates as their studies went on.
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MRC MBU postdocs @mbu-postdocs.bsky.social · 18/11/2024
Hello, world! We are the MRC MBU Postdoctoral Society, and we are very excited to be here! 👩‍🔬👨‍🔬🧪
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