We’re funding 19 teams of world-leading experts spanning fields from mitochondrial and engineering biology to nanotechnology. Explore the projects we're funding in the Precision Mitochondria programme...

Abstract. Variants in the mitochondrial and nuclear genomes are linked to a wide range of human disorders marked by impaired mitochondrial function. Among

The Medical Research Council (MRC) has invested £50 million into the study of mitochondrial diseases to improve treatments.

For many years, the genetic manipulation of mitochondrial DNA was largely hampered by inefficient delivery of nucleic acids to mitochondria. However, the development of mitoCBEs, such as mitochondrial...

The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge wishes to appoint a post-doctoral Research Associate to join the research group of Prof. Michal Minczuk at th...

The London Mitochondrial Centre is hosting a one-day symposium.

The London Mitochondrial Centre is hosting a one-day symposium.

CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

If our website is MitoWorld, the Mechanisms of Mitochondrial DNA Mutation and Repair conference was the introductory gathering of what could be called “mtDNA World.” The organizers, Patrick Chinnery (...

imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...

First-in-class approach to targeting mitochondrial DNA polymerase (POLG) with disease modifying potential across mitochondrial DNA depletion syndromes

Bioinformatician - disease gene discovery - inherited mitochondrial diseases (Fixed Term) in the Division of Neurology at the University of Cambridge.

This week's blog is written by our CEO, Rick Thompson. He discusses our role in the new LifeArc Translational Centres for Rare Disease.