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Lindsey Van Haute

@lindseyvanhaute.bsky.social
584 followers 88 following 73 posts

Next generation sequencing geek and mitochondria lover www.nextgenseqanalysis.com Check out my YouTube channel: www.youtube.com/@SimpleScienceLVH #RNA,#DNA,#mitochondria,#NGS #RNAseq,#Genomics,#bioinformatics,#equality

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Lindsey Van Haute @lindseyvanhaute.bsky.social · 31/03/2026
Study shows that mothers are: - 29% less likely to be employed at a university - 12% reduction in earnings when they left academia - 35% decline in their chance of getting tenure - 31% fewer publications than fathers www.nature.com/articles/d41...
nature.com
Motherhood derails women’s academic careers — these data reveal how and why
Mothers in academia take on considerably more childcare-related responsibilities than do fathers.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 20/01/2026
Friendly reminder from AI-Lindsey: ChatGPT isn’t ‘smart’, it’s obedient. If your prompt is fuzzy, your result will be… creative.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 13/01/2026
Student mental health is in crisis — here’s how to help www.nature.com/articles/d41...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 26/11/2025
www.nature.com/articles/d41...
nature.com
ADHD diagnoses are growing. What’s going on?
More children and adults are being diagnosed with ADHD in some countries. Science is helping to understand why — and how best to provide support.
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NextGenSeek @nextgenseek.bsky.social · 17/11/2025
www.nature.com/immersive/d4...
nature.com
The future of AI
Artificial intelligence is flying high. Nature asked leading innovators what they think will happen next.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 09/11/2025
www.nature.com/articles/d41...
nature.com
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/11/2025
What factors contribute the most to PhD satisfaction? Stipends that are more than just a living wage? Manageable hours? A supportive team? These all matter, and are often in short supply. Another factor often overlooked is supportive supervision. www.nature.com/articles/d41...
nature.com
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 05/10/2025
Higher education is being reshaped by powerful forces — from AI to mental health to decolonization. Six scholars offer fresh ideas for how universities can truly evolve. www.nature.com/articles/d41...
nature.com
Universities must move with the times: how six scholars tackle AI, mental health and more
Societies are evolving, and so must higher education. Researchers describe initiatives that can help to create stimulating and nurturing environments fit for today’s learning landscape.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 02/09/2025
The rise in applications indicates a “huge increase in the amount and cost of work for academics completing these applications”. “[Researchers] must be spending less time either teaching or doing research, and spending more time on writing these grants”. www.nature.com/articles/d41...
nature.com
The grant lottery: award rates at UK national funding agency fall below 20%
Application volume is outpacing available funding, intensifying competition and worsening pressure on the peer-review system. But those who win grants are now getting more.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 01/08/2025
1 AUG
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 15/05/2025
P-hacking Removing outliers, using alternative statistical methods and running extra experiments are some methods that could be used to change the P-value. Be careful not to fall in this trap! Stay sceptical! Null results are a normal part of science. www.nature.com/articles/d41...
nature.com
P hacking — Five ways it could happen to you
Some data practices can lead to statistically dubious findings. Here’s how to avoid them.
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RyanLab_TCD @ryanlab.bsky.social · 30/04/2025
It was fantastic to have @labliston.bsky.social give a talk at the @mrc-mbu.bsky.social on building a positive research culture. Valuable for all investigators/group leaders regardless of career stage, check out the resources below: listonlab.uk/careers/
listonlab.uk
Translational Immunology - Careers
Becoming a Scientist
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 30/04/2025
The temptation to create beautify images can be a slippery slope. www.nature.com/articles/d41...
nature.com
The do’s and don’ts of scientific image editing
Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies.
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NextGenSeek @nextgenseek.bsky.social · 23/04/2025
www.nature.com/articles/d41...
nature.com
Highly sensitive method captures rare RNAs in blood to search for disease
A method for examining RNAs in blood samples offers a clinical tool to detect and monitor cancer and to assess immune responses to vaccination.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 17/04/2025
Stem cells were initially touted as a cure-all, but aside from a few anecdotal studies, this has not been proven true. Is it finally going to happen? www.nature.com/articles/d41...
nature.com
Japan’s big bet on stem-cell therapies might soon pay off with medical breakthroughs
Induced pluripotent stem cells are being tested to treat blindness, paralysis, Parkinson’s disease and more. Approvals might be around the corner.
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EMBO Molecular Medicine @embomolmed.org · 11/04/2025
Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture. By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social 🗞️ doi.org/10.1038/s443... Read also related N&V by A. Ghifari & M. Ott 👉 doi.org/10.1038/s443...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 09/04/2025
Congratulations, Pavel! Proud to have been involved in this project.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 09/04/2025
www.nature.com/articles/d41...
nature.com
Cells are swapping their mitochondria. What does this mean for our health?
Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 28/03/2025
Reposting since it's been a while since I posted this, and new MBU members might have joined.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 27/03/2025
Mitochondria differ in type and density in different parts of the brain. For example, the evolutionarily oldest brain regions have a lower density of mitochondria than newer regions. www.nature.com/articles/d41...
nature.com
First map of human brain mitochondria is ‘groundbreaking’ achievement
Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 25/03/2025
Shared first authorship, but who gets to be first? According to this study, there is no disadvantage to sharing credit. Weakness of the study: The test name was a gender-neutral European name. Can someone please repeat this study with female/non-European names? www.nature.com/articles/d41...
nature.com
Does sharing first authorship on a paper carry a penalty? What the research says
Study dispels myth that order of names in a paper’s author list dictates perception of success.
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Christian Frezza @frezzalab.bsky.social · 21/03/2025
In-cell architecture of the mitochondrial respiratory chain | Science www.science.org/doi/10.1126/...
science.org
In-cell architecture of the mitochondrial respiratory chain
Mitochondria regenerate adenosine triphosphate (ATP) through oxidative phosphorylation. This process is carried out by five membrane-bound complexes collectively known as the respiratory chain, workin...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 21/03/2025
“These findings will need to be confirmed in vivo.“ Animal research can be extremely valuable, but isn't it time to encourage novel alternative non-animal models if they are available? Shouldn't funders encourage research to establish such alternative models more? www.nature.com/articles/d41...
nature.com
How ‘animal methods bias’ is affecting research careers
Some early-career researchers report feeling pressure to use animal models to meet journal and grant requirements, even in disciplines and projects that don’t require them.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 19/03/2025
It is often said that the first responsibility of any government is the safety and protection of its people. Vaccines save lives, and casting doubt on their safety could have dangerous and far-reaching consequences. www.nature.com/articles/d41...
nature.com
Vaccines save lives. Leaders must champion them
Attacks on vaccines and the cancellation of research into what causes vaccine hesitancy puts people in harm’s way.
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Reposted by Lindsey Van Haute
Science Magazine @science.org · 16/03/2025
Can internet use become addictive? A #SciencePerspective discusses the addictive potential of the #internet and how it can be best conceptualized and evaluated. scim.ag/3R5Npv1 #BrainAwarenessWeek
Neural pathways in addiction: The hypothesized main neural circuits in human addictive behaviors are shown. The “feels better” path includes positive and negative reinforcement experiences and involves the ventral striatum (nucleus accumbens), and the dorsal striatum in later stages. The “must do” path includes primarily compulsive behaviors, involving the dorsal striatum (putamen and caudate nucleus). The “stop now” self-control process mainly involves the dorsolateral prefrontal cortex.
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Alexey Amunts @amunts.bsky.social · 15/03/2025
Conference alert: Machines acting on DNA and RNA Madrid, May 28-30 Abstract deadline: April 24 Organised by @cniostopcancer.bsky.social. Come to share your research with experts in the molecular mechanisms of DNA & RNA machines. See the list of speakers below. Please repost.
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The EMBO Journal @embojournal.org · 03/03/2025
Thought that only purine nucleotides could inhibit mitochondrial thermogenesis in brown adipose tissue? Edmund Kunji and coworkers @mitocarriers.bsky.social @mrc-mbu.bsky.social show that pyrimidines bind and inhibit UCP1 in similar manner www.embopress.org/doi/full/10....
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 13/03/2025
Today is World Kidney Day. Are you sure your kidneys are OK? Do the quick test in the link and read about the risks. www.worldkidneyday.org/2025-campaign/
worldkidneyday.org
2025 campaign - World Kidney Day 2025
World Kidney Day – 13 March 2025 Are Your Kidneys OK?Detect early, protectkidney health Are Your Kidneys OK? Take this quiz! Are Your Kidneys OK? Detect early, protect kidney health Chronic kidney dis...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 12/03/2025
Alcohol raises the risk of at least seven types of cancer, including breast, liver, and esophageal cancer. Yet, many drinkers remain unaware. Is there truly a “safe” amount of alcohol? Would a cancer warning label be helpful? htps://www.nature.com/articles/d41586-025-00729-5
nature.com
Alcohol and cancer risk: what you need to know
Experts weigh in on the risks of moderate drinking — and how people should assess them.
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Reposted by Lindsey Van Haute
Science Magazine @science.org · 10/03/2025
"I had spent half my life working toward my dream of being a scientist. It had given me a sense of purpose. But now it dawned on me that, for the sake of my health, I was going to have to let that dream go." This week's #ScienceWorkingLife. scim.ag/4bCwyth
An illustration of a man pushing away a black mass. Hedline is: Science used to be my safe space. But when I spiraled into depression, I quit my Ph.D.
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www.MitoWorld.org @mitoworld.bsky.social · 10/03/2025
New research from Dr Craig Thompson reveals that mitochondria do more than generate energy - they form specialized subpopulations under stress, playing a key role in cancer cell survival. Will this discovery could reshape our understanding of metabolism and disease treatment?
youtube.com
MitoCast: Craig Thompson
YouTube video by MitochondriaWorld™
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 08/03/2025
www.sciencealert.com/internationa...
sciencealert.com
International Women's Day: Female Science Stars to Follow in 2025
Female science communicators are taking social media by storm in 2025.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 06/03/2025
Transgenic mice. Not to be confused with transgender mice. youtu.be/CAtHupHQSEE?...
youtu.be
What Are Transgenic Mice?
YouTube video by Simple Science
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 06/03/2025
Although women still account for only about 35% of the STEMM workforce, research has shown that they are more likely to excel when given access to mentoring, support and guidance from other women with similar lived experiences www.nature.com/articles/d41...
nature.com
Behind every great woman in science, there’s another great woman in science
To mark International Women’s Day on 8 March, six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others.
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The Lily Foundation @lilyfoundation.bsky.social · 28/02/2025
Today is #RareDiseaseDay Did you know there's still no cure for #mitochondrialdisease? @lilyfoundation.bsky.social are fighting to change this. We've invested over £3 million in research since 2007 Please help us to raise awareness of mito Find out more www.thelilyfoundation.org.uk
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 25/02/2025
A new survey finds the top reason: holding onto their professional identity. But does this limit opportunities for younger researchers? Read more: www.science.org/content/arti... #Science #Academia #Retirement
science.org
Why do so many retirement-age scientists keep working?
Survey reveals a desire to hold onto their professional identity keeps Ph.D.s working beyond their 60s
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 13/02/2025
Studies show that members of over-represented groups are more likely to not notice a lack of diversity, whether deliberately or not, and do not always welcome diversity, equity and inclusion efforts that they think they don’t benefit from. www.nature.com/articles/d41...
nature.com
‘Male-dominated campuses belong to the past’: the University of Tokyo tackles the gender gap
A range of initiatives, from financial-support schemes to awareness campaigns, is already changing the university’s environment.
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NextGenSeek @nextgenseek.bsky.social · 06/02/2025
Do you suffer from digital amnesia? Do you remember phone numbers? Do you know your way without a GPS? "We’re gonna lose our memory because we don’t use it anymore," say scientists. What will AI do to our memory? www.nature.com/articles/d41...
nature.com
Are the Internet and AI affecting our memory? What the science says
Search engines, GPS maps and other tech can alter our ability to learn and remember. Now scientists are working out what AI might do.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/02/2025
Second of two videos I made about vaccines for kids & teens! YouTube promotes videos with engagement, so likes/comments/shares help reach the right audience. Even if you're not the target, your support matters! 💙 Watch & boost? 🔗 youtu.be/ScOQ2tt5HQQ #SciComm #Vaccines #ScienceForEveryone
youtu.be
How COVID 19 mRNA Vaccines Are Made and Work
YouTube video by Simple Science
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/02/2025
First of two videos I made about vaccines for kids & teens! YouTube promotes videos with engagement, so likes/comments/shares help reach the right audience. Even if you're not the target, your support matters! 💙 Watch & boost? 🔗 youtu.be/KC42D0ZpqtE #SciComm #Vaccines #ScienceForEveryone
youtu.be
Are vaccines safe?
YouTube video by Simple Science
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 04/02/2025
Cancer is more than just a medical diagnosis—it’s a deeply personal matter. Men, get tested for PSA; Women, book your cervical screening test today. Quit smoking And if you can, donate to cancer research. Together, we can make a difference. #WorldCancerDay #EarlyDetection #FightCancer
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 31/01/2025
Science has gone digital, but have we lost transparency? Too many papers treat bioinformatics like a black box—vague methods, missing parameters, and no reproducibility. Would we accept "we used PCR" without primer details? #Bioinformatics #ScienceIntegrity www.linkedin.com/pulse/hidden...
linkedin.com
The Hidden Risks of Computational Work in Life Sciences: Are We Losing Scientific Transparency?
For decades, life sciences thrived on tangible, observable experiments—gels, blots, and PCR results captured in photographs. Researchers could visually inspect their findings, and reviewers, having gr...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 31/01/2025
Interesting article from @frezzalab.bsky.social.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 29/01/2025
Are all scientists Star Wars fans? 🤔 At #FoG2025, a Star Wars photo op got me thinking—what's the link between genetics & the galaxy far, far away? Is it just nerdy stereotypes? Confession: I'm a scientist who doesn’t like Star Wars. Am I alone in this?
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 27/01/2025
Bluesky is nicer and kinder than X? Sure, but how active are people here on Bluesky? Am I the only one who thinks that many people who signed up aren't really reacting to posts? www.nature.com/articles/d41...
nature.com
Bluesky’s science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
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Athene Donald @athenedonald.bsky.social · 24/01/2025
OUr universities (and industry, schools....) need technicians and their strategic input. wonkhe.com/blogs/we-nee...
wonkhe.com
We need strategic technical leaders
Technicians and the vital work they do must be represented in university leadership, argue Catrin Harris and Hannah Noke Technicians and the vital work they do must be represented in university leader...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 24/01/2025
If 23andMe folds, the fate of its customers’ genetic information is a major worry. What is 23andMe going to do with the data that they still have possession of? Are they going to try to sell access to it in order to generate funds? www.nature.com/articles/d41...
nature.com
What went wrong at 23andMe? Why the genetic-data giant risks collapse
At-home DNA testing is no longer in high demand — and critics have raised concerns about unreliable tests and privacy.
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NextGenSeek @nextgenseek.bsky.social · 22/01/2025
How to help AI to tell the truth? The particular problem of false scientific references is rife. In one 2024 study, various chatbots made mistakes between about 30% and 90% of the time on references. www.nature.com/articles/d41...
nature.com
AI hallucinations can’t be stopped — but these techniques can limit their damage
Developers have tricks to stop artificial intelligence from making things up, but large language models are still struggling to tell the truth, the whole truth and nothing but the truth.
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 20/01/2025
Exciting news! I’ve recently launched a YouTube channel where I explain science in a simple, fun way—perfect for kids and teens! Watch, like, subscribe and share the link! 👉 www.youtube.com/@SimpleScien... Because science should be easy to understand and fun to explore.
youtube.com
Simple Science
We believe that knowledge is power, and our mission is to break down complex topics into simple, bite-sized explanations that anyone can enjoy. From understanding how your organs work to exploring the...
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Lindsey Van Haute @lindseyvanhaute.bsky.social · 20/01/2025
Plagiarism detection tools are powerful, but they often overlook a critical issue: language bias. Non-native English speakers and multilingual authors face unfair challenges, from false positives to inequitable evaluations. www.linkedin.com/posts/lindse...
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