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Lorenzo Lolli

@lorenzololli.bsky.social
177 followers 243 following 139 posts

Lead Researcher at Aspire Academy | Research Fellow at Manchester Metropolitan University | Views are my own

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Lorenzo Lolli @lorenzololli.bsky.social · 01/10/2026
“We counsel authors to 𝐝𝐢𝐬𝐜𝐨𝐧𝐭𝐢𝐧𝐮𝐞 using 𝐩e𝐫c𝐞n𝐭a𝐠e𝐬 and 𝐬i𝐳e-s𝐩e𝐜i𝐟i𝐜 𝐢n𝐝i𝐜e𝐬 in an attempt to scale data for variation in body size within and among groups. Although 𝗿𝗮𝘁𝗶𝗼𝘀 are simple to form and seemingly simple to interpret, they actually are 𝐞𝐱𝐜𝐞𝐞𝐝𝐢𝐧𝐠𝐥𝐲 𝐝𝐞𝐜𝐞𝐩𝐭𝐢𝐯𝐞 and p𝐨t𝐞n𝐭i𝐚l𝐥y m𝐢s𝐥e𝐚d𝐢n𝐠”
researchgate.net
(PDF) The use of percentages and size-specific indices to normalize physiological data for variation in body size: Wasted time, wasted effort?
PDF | Researchers commonly compute percentages or size-specific indices in an attempt to remove effects of body size from physiological data.... | Find, read and cite all the research you need on Rese...
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Retraction Watch @retractionwatch.com · 24/09/2026
"If medical schools and universities don't want the literature to be overwhelmed with garbage," Oransky said, "then they should probably stop giving every applicant ... an incentive to publish a lot of crap."
medpagetoday.com
Is AI Flooding Medical Journals With 'Meaningless' Research?
'It's not fraudulent, and it's not really slop,' one expert says
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Darren Dahly @statsepi.bsky.social · 24/09/2026
Congrats to @jdwilko.bsky.social and everyone who contributed. www.bmj.com/content/394/...
bmj.com
INSPECT-SR tool for assessing trustworthiness of randomised controlled trials
The integrity of evidence synthesis is threatened by problematic randomised controlled trials, where there are serious concerns about the trustworthiness of the data or findings. Such concerns could b...
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Carl T. Bergstrom @carlbergstrom.com · 23/09/2026
Thinking back to the good old days when publishing a paper every three days required some human to be insecure enough to write up two ideas that didn't deserve to see the light of day every single week.
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Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 22/09/2026
This model and the computation are a qualitative advance in using diverse data to estimate human growth patterns. Unlike most models, this one is biologically parameterized, not just curve fitting. Is cool.
Figure 2. Simulated cross-sectional height data for 100 individuals (black points), where the thick black line is the true population-mean growth trajectory and gray lines are true individual trajectories. Horizontal lines connect each point to the potentially-inaccurate “observed” age for that individual (blue circles), which incorporates uncertainty in the age recorded for each child during height measurement. Note that uncertainty tends to increase with age.
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Lorenzo Lolli @lorenzololli.bsky.social · 22/09/2026
“These intervals are reasonably narrow, reflecting the quite large sample size. They show, 𝐡𝐨𝐰𝐞𝐯𝐞𝐫, that e𝐯e𝐧 𝐨n t𝐡e m𝐨s𝐭 𝐨p𝐭i𝐦i𝐬t𝐢c i𝐧t𝐞r𝐩r𝐞t𝐚t𝐢o𝐧 there can be 𝐜o𝐧s𝐢d𝐞r𝐚b𝐥e d𝐢s𝐜r𝐞p𝐚n𝐜i𝐞s between the two methods of measurement and we would conclude that 𝐭h𝐞 𝐝e𝐠r𝐞e o𝐟 𝐚g𝐫e𝐞m𝐞n𝐭 was 𝗻𝗼𝘁 𝗮𝗰𝗰𝗲𝗽𝘁𝗮𝗯𝗹𝗲.”
pubmed.ncbi.nlm.nih.gov
Measuring agreement in method comparison studies - PubMed
Agreement between two methods of clinical measurement can be quantified using the differences between observations made using the two methods on the same subjects. The 95% limits of agreement, estimated by mean difference +/- 1.96 standard deviation of the differences, provide an interval within whi …
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Lorenzo Lolli @lorenzololli.bsky.social · 21/09/2026
𝗨𝗹𝘁𝗿𝗮𝘀𝗼𝘂𝗻𝗱 𝗺𝗲𝘁𝗵𝗼𝗱𝘀 𝗮𝗿𝗲 𝗶𝗻𝗮𝗽𝗽𝗿𝗼𝗽𝗿𝗶𝗮𝘁𝗲 𝘁𝗼 𝗮𝘀𝘀𝗲𝘀𝘀 𝘀𝗸𝗲𝗹𝗲𝘁𝗮𝗹 𝗮𝗴𝗲
zenodo.org
Ultrasound methods are inappropriate to assess skeletal age: Letter to the editor regarding the article "The influence of biological maturity status on the German talent pathway in youth elite soccer:...
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Retraction Watch @retractionwatch.com · 25/08/2026
Ivan Oransky, one of the experts who spoke with ProPublica for this story, said he has encountered other cases where journals failed to retract a study after a university made such a request. “You have a situation where the fox is guarding the henhouse,” he said.
propublica.org
His Research on Pregnant Opioid Users Was Widely Celebrated. Auditors and Experts Found Major Flaws.
Dr. Craig Towers was hailed as a hero for his research on detoxing pregnant opioid users. After he published a study that found naltrexone could help patients stay off drugs, addiction specialists sta...
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Kit Yates @kityates.bsky.social · 15/08/2026
Imagine if Didier Raoult’s (far more consequential) academic misdemeanours had received any where near the media attention Arday’s did. retractionwatch.com/2024/01/08/j...
retractionwatch.com
Journals retract six Didier Raoult papers for ethics violations
Didier Raoult Two journals of a leading microbiology society have retracted six articles by Didier Raoult after a university investigation found breaches of research ethics in his work.  A sev…
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Darren Dahly @statsepi.bsky.social · 13/08/2026
static.klipy.com
The Simpsons: Stop, He's Already Dead!
ALT: The Simpsons: Stop, He's Already Dead!
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Darren Dahly @statsepi.bsky.social · 04/08/2026
Stop trying to explain what a p-value is in a single sentence (ICYMI) statsepi.substack.com/p/no-you-can...
statsepi.substack.com
No, you can't explain what a p-value is with one sentence (Parts I, II)
But I'm going to try and do it in as few as possible. #fml
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Lorenzo Lolli @lorenzololli.bsky.social · 27/07/2026
“Causal inferential methods require t𝐡e u𝐬e o𝐟 𝐜o𝐮n𝐭e𝐫f𝐚c𝐭u𝐚l𝐬 that are 𝐧𝐨𝐭 𝐢𝐧𝐟𝐨𝐫𝐦𝐞𝐝 𝐛𝐲 𝐚𝐧𝐲 𝐝𝐚𝐭𝐚 (𝗼𝘂𝘁𝘀𝗶𝗱𝗲 𝗼𝗳 𝗰𝗿𝗼𝘀𝘀𝗼𝘃𝗲𝗿 𝘀𝘁𝘂𝗱𝗶𝗲𝘀) and make 𝐚𝐬𝐬𝐮𝐦𝐩𝐭𝐢𝐨𝐧𝐬 that are 𝙪𝒏𝙫𝒆𝙧𝒊𝙛𝒊𝙖𝒃𝙡𝒆, e.g., about the 𝐜o𝐫r𝐞l𝐚t𝐢o𝐧 𝐬t𝐫u𝐜t𝐮r𝐞 𝒐𝙛 𝙥𝒐𝙩𝒆𝙣𝒕𝙞𝒂𝙡 𝙤𝒖𝙩𝒄𝙤𝒎𝙚𝒔.” Excellent read, @f2harrell.bsky.social.
fharrell.com
Statistical Models Answer the Fundamental Clinical Question and Provide Clinical Trial Estimands – Statistical Thinking
Specific goals and estimation targets for randomized clinical trials have still not been well defined for general outcome variables. Proponents of causal inference calculus have claimed to define goal...
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Lorenzo Lolli @lorenzololli.bsky.social · 27/07/2026
“C𝐨u𝐧t𝐞r𝐟a𝐜t𝐮a𝐥-based attempts at ii𝐧d𝐢v𝐢d𝐮a𝐥 𝐩a𝐭i𝐞n𝐭 𝐝e𝐜i𝐬i𝐨n m𝐚k𝐢n𝐠 have led to 𝐧𝐨𝐭𝐡𝐢𝐧𝐠 𝐛𝐮𝐭 𝐜𝐨𝐧𝐟𝐮𝐬𝐢𝐨𝐧” 🔗nice read by @f2harrell.bsky.social: www.fharrell.com/post/rctmod/
fharrell.com
Statistical Models Answer the Fundamental Clinical Question and Provide Clinical Trial Estimands – Statistical Thinking
Specific goals and estimation targets for randomized clinical trials have still not been well defined for general outcome variables. Proponents of causal inference calculus have claimed to define goal...
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George Davey Smith @mendelrandom.bsky.social · 22/07/2026
Does the (live) shingles vaccine protect against dementia? Fergus Hamilton and colleagues provide important evidence in a new preprint using hospital data from the whole of England in a regression discontinuity design from which we *don't* show evidence of a meaningful protective effect /cont
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Lorenzo Lolli @lorenzololli.bsky.social · 21/07/2026
“There are also serious philosophical objections to regarding 𝐩o𝐭e𝐧t𝐢a𝐥 𝐫e𝐬p𝐨n𝐬e𝐬 𝙖𝒔 𝒉𝙖𝒗𝙞𝒏𝙜 𝙧𝒆𝙖𝒍 𝒆𝙭𝒊𝙨𝒕𝙚𝒏𝙘𝒆.” @philipdawid.bsky.social, @stephensenn.bsky.social. 𝐏𝐞𝐫𝐬𝐨𝐧𝐚𝐥𝐢𝐬𝐞𝐝 𝐃𝐞𝐜𝐢𝐬𝐢𝐨𝐧-𝐌𝐚𝐤𝐢𝐧𝐠 𝐰𝐢𝐭𝐡𝐨𝐮𝐭 𝐂𝐨𝐮𝐧𝐭𝐞𝐫𝐟𝐚𝐜𝐭𝐮𝐚𝐥𝐬. arXiv:2301.11976v2 [stat.ME] 2023. lnkd.in/d2hddCKH
arxiv.org
Personalised Decision-Making without Counterfactuals
This article is a response to recent proposals by Pearl and others for a new approach to personalised treatment decisions, in contrast to the traditional one based on statistical decision theory. We a...
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Julia M. Rohrer @dingdingpeng.the100.ci · 21/07/2026
Sobering: initial trials with huge effect, large follow-up trial showing no evidence for an effect. But practice is already locked in and criticism is defused by pointing to random effects meta-analyses which are necessarily dominated by the initial trials. polypharmacy.substack.com/p/we-should-...
polypharmacy.substack.com
We should stop running clinical trials that cannot change practice
The case of prazosin for PTSD nightmares and the PACT trial
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Lorenzo Lolli @lorenzololli.bsky.social · 19/07/2026
“The p𝐨t𝐞n𝐭i𝐚l r𝐞s𝐩o𝐧s𝐞 𝐟r𝐚m𝐞w𝐨r𝐤, introduced by Neyman (1923) and reintroduced and popularised by Rubin (1974), is often taken to be f𝐮n𝐝a𝐦e𝐧t𝐚l t𝐨 𝐭h𝐞 𝐜o𝐧d𝐮c𝐭 𝐨f c𝐚u𝐬a𝐥 𝐢n𝐟e𝐫e𝐧c𝐞. However…” @philipdawid.bsky.social | @stephensenn.bsky.social
arxiv.org
Personalised Decision-Making without Counterfactuals
This article is a response to recent proposals by Pearl and others for a new approach to personalised treatment decisions, in contrast to the traditional one based on statistical decision theory. We a...
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Martin Modrák @modrakm.bsky.social · 17/07/2026
Multiverse analysis, abdication of responsibility and manufacturing of doubt: I have written on some downsides I see with multiverse analysis (which I like in principle): arxiv.org/abs/2607.14623 I was inspired/provoked to write it by @dingdingpeng.the100.ci (thanks!)
Abstract: I argue that multiverse analysis is highly suited to two undesirable uses: abdication of researcher's responsibility for their conclusion and manufacturing of doubt. A review of multiverse analyses published in 2025 provides tentative empirical support that abdication of responsibility is present in the literature and I mention anecdotal evidence that multiverse has been used for manufacturing of doubt about Covid-19 precautions. To mitigate negative effects if multiverse analysis becomes widely used I suggest the community adopts two conventions for evaluating multiverse analyzes: evaluating multiverses by the single worst universe they contain and considering large size of a multiverse as a sign of weakness rather than a praiseworthy achievement.
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Darren Dahly @statsepi.bsky.social · 10/07/2026
Preach on it, amen.
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Lorenzo Lolli @lorenzololli.bsky.social · 10/07/2026
“In the case of a 𝗿𝗮𝘁𝗶𝗼 𝗮𝘀 𝗲𝘅𝗽𝗼𝘀𝘂𝗿𝗲, how do we know whether the 𝐜a𝐮s𝐚l e𝐟f𝐞c𝐭 of c𝐡a𝐧g𝐢n𝐠 𝐚 𝐫a𝐭i𝐨 is d𝐮e t𝐨 changing the 𝗻𝘂𝗺𝗲𝗿𝗮𝘁𝗼𝗿, the 𝒅𝙚𝒏𝙤𝒎𝙞𝒏𝙖𝒕𝙤𝒓, or b𝐨t𝐡?
academic.oup.com
Ratios in regression analyses with causal questions
Ratio measures are often used in medical research. Generally, the reason is to describe a phenomenon with a single number rather than multiple numbers. In
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Retraction Watch @retractionwatch.com · 08/07/2026
Yannick Griep, a former rising star in management research at Radboud University in the Netherlands, is set to lose an undisclosed number of articles from a journal he once edited, Retraction Watch has learned.
retractionwatch.com
Exclusive: Sage to retract multiple articles by dismissed rising star for “compromised” peer-review process
Yannick Griep, a former rising star in management research at Radboud University in the Netherlands, is set to lose an undisclosed number of articles from a journal he once edited, Retraction Watch…
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Retraction Watch @retractionwatch.com · 09/07/2026
Th resigning editors say the publisher’s decision to become fully open access is “irreconcilable with our vision of science.” According to the journal’s homepage, all submissions from July 1 that end up in the journal will be subject to a $2,990 article processing charge (APC).
retractionwatch.com
‘The exploitation still remains’: Stats journal associate editors resign over $3,000 publishing charge
Eighteen associate editors of the journal Statistics and Computing have announced they will resign after Springer Nature announced the journal would require a fee to publish.  In a July 8 stat…
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Lorenzo Lolli @lorenzololli.bsky.social · 30/06/2026
“If an intervention 𝒊𝒏𝒕𝒆𝒓𝒂𝒄𝒕𝒔 𝒘𝒊𝒕𝒉 participant characteristics, some participants will see larger impacts on their outcome than others.” Higgins, J.P.T. and Li, T. (2022). Exploring Heterogeneity. In Systematic Reviews in Health Research (eds M. Egger, J.P.T. Higgins and G. Davey Smith).
onlinelibrary.wiley.com
Exploring Heterogeneity
Studies brought together in a meta-analysis are likely to vary in terms of where, when, why, and how they were undertaken. This diversity across the studies often gives rise to heterogeneity: the sta...
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Daniel Lakens @lakens.bsky.social · 21/06/2026
New preprint: There is only one correct analysis. osf.io/preprints/ps... with @sajedehra.bsky.social and @mntunc.bsky.social We take a critical look at recent proposals for multiverse or many analyst procedures, and strongly argue that epistemic uncertainty should be reduced, not “embraced”. >
osf.io
OSF
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Florian Naudet @floriannaudet.bsky.social · 02/06/2026
Super happy to have contributed to this super important and timely paper, "Using Routinely Collected Data for Research Purposes: Challenges and Mitigation Strategies", led by @sabinehoffmann11.bsky.social and just published in @bmj.com... www.bmj.com/content/393/...
bmj.com
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Lorenzo Lolli @lorenzololli.bsky.social · 02/06/2026
𝗕𝗮𝗰𝗸-𝘁𝗿𝗮𝗻𝘀𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗿𝗮𝗻𝗱𝗼𝗺-𝗲𝗳𝗳𝗲𝗰𝘁𝘀 𝗺𝗲𝘁𝗮-𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀—𝗜𝗺𝗽𝗮𝗰𝘁 𝗮𝗻𝗱 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁𝗮𝘁𝗶𝗼𝗻. Igelmann JB, Pauly M, @wviechtb.bsky.social. Res Synth Methods. 2026 May 15:1-14. doi: 10.1017/rsm.2026.10096.
cambridge.org
Back-transformations in random-effects meta-analysis—Impact and interpretation | Research Synthesis Methods | Cambridge Core
Back-transformations in random-effects meta-analysis—Impact and interpretation
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Lorenzo Lolli @lorenzololli.bsky.social · 25/05/2026
𝗚𝗲𝗻𝗲𝗿𝗮𝗹𝗶𝘇𝗲𝗱 𝗔𝗱𝗱𝗶𝘁𝗶𝘃𝗲 𝗠𝗼𝗱𝗲𝗹𝘀. Wood SN. 𝐀𝐧𝐧𝐮𝐚𝐥 𝐑𝐞𝐯𝐢𝐞𝐰 𝐨𝐟 𝐒𝐭𝐚𝐭𝐢𝐬𝐭𝐢𝐜𝐬 𝐚𝐧𝐝 𝐈𝐭𝐬 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧. 2025;12(Volume 12, 2025):497–526.
annualreviews.org
Generalized Additive Models
Generalized additive models are generalized linear models in which the linear predictor includes a sum of smooth functions of covariates, where the shape of the functions is to be estimated. They have...
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Peter Tennant @pwgtennant.bsky.social · 24/05/2026
Last week, there was widespread indignation at the revelation that some researchers in STEM might not be reading the papers they cite. Here's a recent example of the standard state of affairs in Medicine and Health, published in @bmj.com, one of the world's leading medical journals! 1/5 🧵
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Georgia Tomova @georgiatomova.bsky.social · 24/05/2026
Tell me you don't understand Bland-Altman limits of agreement without telling me. Authors: "93.5% (100/107) of pairs fell within 95% limits of agreement"
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Lorenzo Lolli @lorenzololli.bsky.social · 21/05/2026
“𝐂𝐨𝐫𝐫𝐞𝐥𝐚𝐭𝐢𝐨𝐧 implies specific types of association such as monotone trends or clustering, 𝒃𝙪𝒕 𝒏𝙤𝒕 𝒄𝙖𝒖𝙨𝒂𝙩𝒊𝙤𝒏.” 🔗: moodle2.units.it/pluginfile.p...
pubmed.ncbi.nlm.nih.gov
Association, correlation and causation - PubMed
Association, correlation and causation
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Darren Dahly @statsepi.bsky.social · 20/05/2026
New paper from colleagues in the @hpscireland.bsky.social w/ James Gleeson @unioflimerick.bsky.social Detecting changepoints in dynamical systems: Modeling time-varying transmission of seasonal influenza www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Lorenzo Lolli @lorenzololli.bsky.social · 20/05/2026
“As 𝙩𝙝𝙚 𝙨𝙮𝙨𝙩𝙚𝙢 𝙚𝙣𝙘𝙤𝙪𝙧𝙖𝙜𝙚𝙨 𝙥𝙤𝙤𝙧 𝙧𝙚𝙨𝙚𝙖𝙧𝙘𝙝 it is the system that should be changed. We need less research, better research, and 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐝𝐨𝐧𝐞 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐫𝐢𝐠𝐡𝐭 𝐫𝐞𝐚𝐬𝐨𝐧𝐬. 𝘼𝙗𝙖𝙣𝙙𝙤𝙣𝙞𝙣𝙜 𝙪𝙨𝙞𝙣𝙜 𝙩𝙝𝙚 𝙣𝙪𝙢𝙗𝙚𝙧 𝙤𝙛 𝙥𝙪𝙗𝙡𝙞𝙘𝙖𝙩𝙞𝙤𝙣𝙨 𝙖𝙨 𝙖 𝙢𝙚𝙖𝙨𝙪𝙧𝙚 𝙤𝙛 𝙖𝙗𝙞𝙡𝙞𝙩𝙮 𝙬𝙤𝙪𝙡𝙙 𝙗𝙚 𝙖 𝙨𝙩𝙖𝙧𝙩.”
pubmed.ncbi.nlm.nih.gov
The scandal of poor medical research - PubMed
The scandal of poor medical research
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Peter Tennant @pwgtennant.bsky.social · 17/05/2026
"Standard research practice in medical research" = "Is this research misconduct"?
"Is this a pigeon meme". The man, labelled "academics from other disciplines", is pointing at the butterfly labelled "standard research practice in medical research", he asks "is this research misconduct?"
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Lorenzo Lolli @lorenzololli.bsky.social · 18/05/2026
“The percentage of predicted adult height, whether determined using the Khamis-Roche method or any alternative protocol, is an inconsistent simple ratio statistic for determining the extent of completed growth in adolescent athletes.”
journals.lww.com
The Khamis-Roche Percentage of Predicted Adult Height as a... : Medicine & Science in Sports & Exercise
thletes. Methods: A secondary data analysis of publicly available, de-identified, cross-sectional data relevant to 139 male youth soccer players (age range, 12.2 to 15.2 yr). Assumptions for accura...
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Lorenzo Lolli @lorenzololli.bsky.social · 15/05/2026
“The 𝒍𝙞𝒎𝙞𝒕𝙖𝒕𝙞𝒐𝙣𝒔 𝒐𝙛 𝙧𝒂𝙩𝒊𝙤𝒔 such as the BMI in human growth research have been well known since James Tanner’s 1949 expose on the topic (Tanner 1949a)”…
cambridge.org
Basic Principles of Human Growth (Chapter 2) - Patterns of Human Growth
Patterns of Human Growth - November 2020
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Wolfgang Viechtbauer @wviechtb.bsky.social · 06/05/2026
Ian Hussey (@ianhussey.mmmdata.io) contacted me about the recurring problem of unusually large SMD values appearing in published meta-analyses. Very large SMDs can result from using SEs in place of SDs in their calculation, which is a mistake I have also seen in practice. 1/4
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Wolfgang Viechtbauer @wviechtb.bsky.social · 07/05/2026
Speaking of crazy d values, this reminds me of this feature I was thinking about adding to the forest() function in metafor. #Rstats #MetaAnalysis
A forest plot showing emojis in place of the points.
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Reposted by Lorenzo Lolli
Ketan Joshi @ketanjoshi.co · 04/05/2026
A big study that was cited as evidence that text generators are good for students has been retracted: www.linkedin.com/posts/ben-wi... www.nature.com/articles/s41...
Retraction Note: The effect of ChatGPT on students’ learning performance, learning perception, and higher-order thinking: insights from a meta-analysis
Jin Wang & Wenxiang Fan 
Humanities and Social Sciences Communications volume 13, Article number: 528 (2026) Cite this article

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The Original Article was published on 06 May 2025

Retraction Note to: Humanities and Social Sciences Communications https://doi.org/10.1057/s41599-025-04787-y, published online 06 May 2025

The Editor has decided to retract this paper owing to concerns regarding discrepancies in the meta-analysis. These issues ultimately undermine the confidence the Editor can place in the validity of the analysis and resulting conclusions. The authors have not responded to correspondence regarding this retraction.
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Reposted by Lorenzo Lolli
Andrew Gelman et al. @statmodeling.bsky.social · 02/05/2026
John Carlin says, “‘Identifying variables that independently predict…’ is not a well-defined research task” statmodeling.stat.columbia.edu/2026/05/02/5...
statmodeling.stat.columbia.edu
John Carlin says, “‘Identifying variables that independently predict…’ is not a well-defined research task” | Statistical Modeling, Causal Inference, and Social Science
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Darren Dahly @statsepi.bsky.social · 28/04/2026
🎯So many important points packed into this editorial. ht @maartenvsmeden.bsky.social www.nature.com/articles/s41...
nature.com
Show us the evidence for the value of medical AI - Nature Medicine
Claims that medical AI is improving care must be backed by appropriate evidence.
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Nikos Margaritelis @margaritelis.bsky.social · 28/04/2026
Happy to share our publication in FRBM. We used aggregated sets of n-of-1 trials to study individual oxidative stress & inflammation responses to vit C supplementation. Huge thanks to @lorenzololli.bsky.social @gregatki.bsky.social @mg-nikolaidis.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Individual oxidative stress and inflammation responses to vitamin C supplementation: Aggregated sets of n-of-1 trials
Personalized antioxidant supplementation is promoted to optimize redox balance and inflammation profile.To quantify the short-term effects of vitamin …
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Reposted by Lorenzo Lolli
Martin Plöderl @ploederl.bsky.social · 19/04/2026
1. The paper with the implausibly large effects of Omega-3 fatty acids on mental health was now retracted. A little thread on the process where @ianhussey.mmmdata.io and I was involved. www.sciencedirect.com/science/arti...
sciencedirect.com
RETRACTED: The effects of Omega-3 supplementation on stress, anxiety, depression, sleep quality, and everyday memory in individuals with psychological distress: A randomized, double-blind, placebo-con...
This article has been retracted: please see Elsevier policy on Article Correction, Retraction and Removal (https://www.elsevier.com/about/policies-and…
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Graham Kendall @grahamkendall.bsky.social · 09/04/2026
How AI use in scholarly publishing threatens research integrity, lessens trust, and invites misinformation
thebulletin.org
How AI use in scholarly publishing threatens research integrity, lessens trust, and invites misinformation
Since 2023, a significant number of published scholarly papers show signs of having been edited using AI tools. These tools are also being used to review papers and search and discovery tools, in…
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Reposted by Lorenzo Lolli
Elisabeth Bik @elisabethbik.bsky.social · 07/04/2026
48th #Retraction for Didier Raoult - by @plosone.org - because the IRB approvals did not cover all regions and experiments. PubPeer concerns raised by me in March 2021: pubpeer.com/publications... journals.plos.org/plosone/arti...
pubpeer.com
PubPeer - Eukaryote Culturomics of the Gut Reveals New Species
There are comments on PubPeer for publication: Eukaryote Culturomics of the Gut Reveals New Species (2014)
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Thom Baguley @seriousstats.bsky.social · 06/04/2026
Just saw this new paper by Brauer on how linear models of mean effect can be very misleading for ordinal data link.springer.com/article/10.1...
link.springer.com
When the Mean is Misleading: a Guide to Ordered Regression for Meaningfully Modeling Ordinal Outcomes - Journal of Quantitative Criminology
Journal of Quantitative Criminology - We demonstrate the utility of ordered regression models for analyzing ordinal outcomes frequently encountered in criminology, comparing their predictive...
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Stephen Senn @stephensenn.bsky.social · 30/03/2026
So you carried out a controlled clinical trial? Bravo. Make sure you carry out a controlled analysis. You can bin those within-group standard errors, comparisons back to baselines and dynamite detonator plots for a start. pubmed.ncbi.nlm.nih.gov/2277879/
pubmed.ncbi.nlm.nih.gov
The graphical representation of clinical trials with particular reference to measurements over time - PubMed
Clinical trials are frequently analysed as if they were surveys when they are in fact experiments. In particular the experimental basis of clinical trials is rarely reflected in the graphs which are used to illustrate them. Proposals are made, and illustrated by example, as to how appropriate figure …
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Frank Harrell @f2harrell.bsky.social · 28/03/2026
Nice paper on effective sample size for Kaplan-Meier survival curve estimates: www.tandfonline.com/doi/full/10.... #Statistics #StatsSky
tandfonline.com
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Lorenzo Lolli @lorenzololli.bsky.social · 27/03/2026
𝗦𝗜𝗧𝗔𝗥-𝗱: 𝗲𝘅𝘁𝗲𝗻𝗱𝗶𝗻𝗴 𝘁𝗵𝗲 𝗦𝗜𝗧𝗔𝗥 𝗴𝗿𝗼𝘄𝘁𝗵 𝗰𝘂𝗿𝘃𝗲 𝗺𝗼𝗱𝗲𝗹 𝘁𝗼 𝗮𝗹𝗹𝗼𝘄 𝗳𝗼𝗿 𝘃𝗮𝗿𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗶𝗻 𝗽𝗼𝘀𝘁-𝗽𝘂𝗯𝗲𝗿𝘁𝗮𝗹 𝘃𝗲𝗹𝗼𝗰𝗶𝘁𝘆. Cole, T. J., Sandhu, S., & Elhakeem, A. (2026). @annalshumanbio.bsky.social, 53(1). doi.org/10.1080/0301....
doi.org
SITAR-d: extending the SITAR growth curve model to allow for variability in post-pubertal velocity
The SITAR growth curve model with its three random effects is useful for summarising height growth in individuals and groups. However SITAR performs less well for weight which unlike height continu...
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Elisabeth Bik @elisabethbik.bsky.social · 25/03/2026
I wrote a perspective for Anesthesia & Analgesia - "Seeing Is Believing? Scientific Misconduct and the Detection of Problematic Images" Still trying to make it Open Access. Fingers crossed! journals.lww.com/anesthesia-a...
journals.lww.com
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Laure Wynants @laurewynants.bsky.social · 18/03/2026
✨ New open-access book✨ I’ve seen how powerful prediction models can be, but also how often they fall short. We wrote a book, covering not just development, but also when models are needed, and how to ensure real-world impact. www.maastrichtuniversitypress.nl/cpm
maastrichtuniversitypress.nl
%%title%% %%sep%% Maastricht University Press
Open Access book by Luc Smits, Sander van Kuijk, and Laure Wynants: This open-access textbook offers a practical and comprehensive guide to developing, validating, and implementing clinical prediction...
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